Device and method for medical Raman spectrum detection

By using a single fiber and a collection fiber with a fiber Bragg grating in a Raman probe device, combined with a spectroscopic beam lens set, the existing Raman probe signal crosstalk and complex operation problems are solved, achieving high-accuracy Raman signal acquisition and simplified detection operations.

CN119915793APending Publication Date: 2025-05-02奥谱天成(湖南)信息科技有限公司
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Patent Information

Application Number
CN202510099619.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-21
Publication Date
2025-05-02

AI Technical Summary

Technical Problem

The existing Raman probes have severe signal crosstalk during in vitro detection, and are complex in vivo detection and costly, making it difficult to achieve fast, real-time, lightweight and pollution-free detection.

Method used

The excitation and signal collection are carried out using a single optical fiber, combined with the spectrosynthetic beam lens set and the collection fiber with the optical fiber Bragg grating, to achieve the purity and singularity of the Raman signal and improve the signal-to-noise ratio.

Benefits of technology

It realizes the purity and singularity of Raman signal acquisition, improves the accuracy and reliability of data analysis, simplifies optical fiber operation and replacement, and is suitable for in vivo detection of living humans or animals.

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Abstract

The invention provides a device and a method for medical Raman spectrum detection, and belongs to the technical field of Raman spectrum detection. The device comprises a laser used for emitting laser to a sample; the Raman probe device is configured to comprise a laser excitation light path and a Raman signal collection light path, the laser excitation light path is used for transmitting the laser emitted by the laser to the sample, and the Raman signal collection light path is used for collecting Raman signal light generated after the laser excites the sample; and the spectrograph is used for receiving the Raman signal light from the Raman signal collection light path and carrying out spectrogram collection and analysis on the Raman signal light. According to the device for medical Raman spectrum detection, the position consistency of Raman signal light of an excitation sample and a collection sample can be ensured, signal crosstalk is effectively blocked, the purity and the singleness of Raman signal collection are realized, and the accuracy and the reliability of data analysis are improved.
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