Evaluation system for neurogenic bladder function state of spinal cord injury patient

Abstract

The invention relates to the technical field of medical analysis and evaluation, in particular to a spinal cord injury patient neurogenic bladder function state evaluation system which comprises a basic information acquisition module, a bladder function dynamics examination and evaluation module, a bladder tissue detection and analysis module and a bladder function state evaluation module. Basic information of a spinal cord injury patient is obtained based on a basic information acquisition module; urodynamic examination information of a spinal cord injury patient is obtained by using a bladder function dynamic examination and evaluation module, and the above modules are combined with the urodynamic examination information and basic information to obtain a bladder dynamic evaluation result; the bladder tissue detection and analysis module obtains tissue detection information of a spinal cord injury patient, and the module obtains a bladder tissue analysis result according to the tissue detection information and basic information; and the bladder function state evaluation module comprehensively evaluates the neurogenic bladder function state of the patient according to the basic information, the bladder dynamics evaluation result and the bladder tissue analysis result.

Description

Technical Field

[0001] The present invention relates to the technical field of medical analysis and evaluation, and in particular to an evaluation system for the functional state of neurogenic bladder in patients with spinal cord injury. Background Art

[0002] Spinal cord injury is a severe neurological injury that can cause functional abnormalities in the bladder, bladder neck, or sphincter, a condition known as neurogenic bladder. The clinical manifestations of this condition depend on the exact location and extent of the nerve damage, and can be extremely distressing for patients. Furthermore, patients can suffer from bowel dysfunction, sexual dysfunction, and psychological issues, all of which threaten their mental health and severely impact their quality of life.

[0003] Currently, existing assessment systems do not provide a comprehensive reference scale for evaluating neurogenic bladder symptoms. Although existing assessment means and methods are diverse, there are still significant deficiencies in data processing and optimization, resulting in inaccurate symptom assessment results. Therefore, it is necessary to design an assessment system for the functional status of neurogenic bladder in patients with spinal cord injury that can monitor and obtain relevant patient data in real time, and test, analyze, and process the relevant data to help the system achieve accurate assessment and analysis of patient symptoms. At the same time, based on the target assessment data and reference system, a comprehensive analysis of the patient's symptoms can be conducted, thereby providing advice and guidance for adjusting the treatment plan. Summary of the Invention

[0004] In view of the shortcomings of existing methods and the needs of practical applications, in order to comprehensively evaluate the patient's bladder function, accurately grasp its functional status, and then customize accurate and efficient treatment plans for patients, and make necessary adjustments and optimizations to the treatment plans based on the feedback from functional evaluation to achieve the best treatment effect. The present invention proposes an evaluation system for the neurogenic bladder function status of patients with spinal cord injury. The system optimizes patient data and obtains data analysis results. Based on the analysis results, monitoring indicators are provided for treatment effects to ensure the effectiveness and feasibility of the patient's treatment plan. The system includes: a basic information acquisition module, a bladder function dynamics examination and evaluation module, a bladder tissue detection and analysis module, and a bladder function status evaluation module. Basic information of the spinal cord injury patient is obtained based on the basic information acquisition module; urodynamic examination information of the spinal cord injury patient is obtained using the bladder function dynamics examination and evaluation module, and the bladder function dynamics examination and evaluation module combines the urodynamic examination information and the basic information to obtain a bladder dynamics evaluation result of the spinal cord injury patient; tissue detection information of the spinal cord injury patient is obtained through the bladder tissue detection and analysis module, and the bladder tissue detection and analysis module obtains a bladder tissue analysis result of the spinal cord injury patient based on the tissue detection information and the basic information; and the bladder function status evaluation module comprehensively evaluates the neurogenic bladder function status of the spinal cord injury patient based on the basic information, the bladder dynamics evaluation result, and the bladder tissue analysis result. The system of the present invention integrates multiple modules to comprehensively collect and analyze patient information, ensuring the comprehensiveness and accuracy of the evaluation information. The bladder dynamics evaluation results and bladder tissue analysis results complement each other, providing more comprehensive and accurate information on bladder function status.

[0005] Optionally, obtaining urodynamic examination information of a patient with spinal cord injury using the bladder function dynamics examination and evaluation module includes: obtaining detrusor electromyography (EMG) information of the patient using the bladder function dynamics examination and evaluation module; and analyzing the urodynamic examination information of the patient with spinal cord injury based on the detrusor EMG information and the basic information, the urodynamic examination information including leak point pressure data, urination bladder capacity data, and urination interval data. The detrusor EMG information of the present invention can directly reflect the functional status of the detrusor muscle, helping to accurately determine the contractility and coordination of the bladder, thereby improving the accuracy of the system's evaluation results.

[0006] Optionally, obtaining the patient's detrusor electromyogram information using the bladder function dynamics examination and evaluation module includes: providing a monitoring image processing model in the bladder function dynamics examination and evaluation module; and the bladder function dynamics examination and evaluation module using the monitoring image processing model to process the initial detrusor electromyogram to obtain the patient's detrusor electromyogram information. The monitoring image processing model of the present invention can process the initial detrusor electromyogram, shortening data processing time, reducing errors caused by human factors, and improving the accuracy of monitoring information.

[0007] Optionally, the bladder function dynamics examination and evaluation module processes the initial detrusor electromyogram using the monitoring image processing model and obtains the patient's detrusor electromyogram information, including: setting a monitoring image processing model based on the basic information and the initial detrusor electromyogram, the monitoring image processing model including a signal waveform analysis model and a vibration amplitude analysis model; and the bladder function dynamics examination and evaluation module processes the initial detrusor electromyogram using the signal waveform analysis model and the vibration amplitude analysis model to obtain the patient's detrusor electromyogram information. The present invention utilizes a monitoring image processing model to process the initial detrusor electromyogram, thereby improving the accuracy and objectivity of the evaluation results and having important clinical significance and practical application value.

[0008] Optionally, the signal waveform analysis model satisfies the following relationship:

[0009] in, Represents the signal waveforms of different sub-time periods, Indicates the center frequency of the signal waveform, Indicates the sampling time corresponding to different sub-time periods, Indicates the signal frequency modulation slope in different sub-time periods, Indicates the pulse width of a single signal, Parameters indicating the effect of needle electrode treatment on signal pulse width, express The signal waveform analysis model of the present invention introduces multiple parameters, which not only improves the accuracy of signal analysis, but also helps to more accurately evaluate the functional status of the bladder and discover potential abnormal changes.

[0010] Optionally, the vibration amplitude analysis model satisfies the following relationship:

[0011] in, Indicates the vibration amplitude corresponding to the monitoring time, Indicates the number of sub-time periods within the monitoring time. express The vibration peak value of the electrical signal in the sub-time period, Indicates the influence coefficient of needle electrode treatment program on electrical signals, express The average angular frequency of the electrical signal in the sub-time period, express The weight coefficient of the electrical signal in the sub-time period, express The initial phase angle of the sub-time period. The model of the present invention divides the monitoring time into different sub-time periods for analysis, which can capture subtle changes in vibration characteristics in different time periods, which is helpful for subsequent evaluation of bladder function.

[0012] Optionally, the bladder function dynamics examination and evaluation module combines the urodynamic examination information and the basic information to obtain a bladder dynamics evaluation result for the spinal cord injury patient, including: the bladder function dynamics examination and evaluation module analyzes the leak point pressure data, the urination bladder capacity data, the urination interval data, and the basic information to obtain a bladder dynamics evaluation result for the spinal cord injury patient. The present invention combines leak point pressure data, urination bladder capacity data, urination interval data, and other information to comprehensively assess the bladder function status of spinal cord injury patients. This comprehensive evaluation method can more accurately reflect the dynamic characteristics of the bladder.

[0013] Optionally, obtaining tissue detection information of a spinal cord injury patient through the bladder tissue detection and analysis module includes obtaining tissue detection information of a spinal cord injury patient through the bladder tissue detection and analysis module, wherein the tissue detection information includes detrusor muscle cell apoptosis data, fibrosis information, and detrusor M receptor mRNA expression information of the spinal cord injury patient. The module of the present invention can generate personalized patient evaluation results, which helps to more accurately understand the bladder function status of different patients and provide a basis for formulating personalized treatment plans.

[0014] Optionally, the bladder tissue detection and analysis module obtains bladder tissue analysis results of spinal cord injury patients based on the tissue detection information and the basic information, including: analyzing the degree of apoptosis of detrusor muscle cells based on the detrusor muscle cell apoptosis data and the basic information; analyzing the proportion of collagen fibers in the detrusor muscle tissue based on the fibrosis information and the basic information; analyzing the relative expression level of M receptor mRNA based on the detrusor muscle M receptor mRNA expression information and the basic information; and obtaining bladder tissue analysis results of spinal cord injury patients in combination with the apoptosis degree, the proportion, and the relative expression level. The present invention analyzes the degree of apoptosis of detrusor muscle cells, the proportion of collagen fibers, and the relative expression level of M receptor mRNA, thereby accurately locating the lesion site of bladder tissue and analyzing the degree of lesion.

[0015] Optionally, the bladder function status assessment module comprehensively assesses the neurogenic bladder function status of the spinal cord injury patient based on the basic information, the bladder dynamics evaluation results, and the bladder tissue analysis results, including: introducing historical assessment record information of the neurogenic bladder function status; the bladder function status assessment module comprehensively assesses the neurogenic bladder function status of the spinal cord injury patient based on the basic information, the leak point pressure data, the urination bladder capacity data, the urination time interval data, the apoptosis degree, the proportion, and the relative expression level, and obtains a comprehensive assessment result; the comprehensive assessment result is compared with the historical assessment record information, and the treatment plan for the patient's neurogenic bladder after spinal cord injury is adjusted and optimized based on the comparison result. The present invention introduces historical assessment record information to further conduct a longitudinal comparison of the patient's bladder function status and observe its changing trend, which helps to more accurately judge the treatment effect of different patients and optimize the treatment plan. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a flow chart of the system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury according to the present invention; Figure 2 Schematic diagram of the processed detrusor electromyogram vibration waveform in the system for evaluating the neurogenic bladder function status of spinal cord injury patients of the present invention; Figure 3 Schematic diagram of the detrusor electromyogram vibration waveform before treatment in the system for evaluating the neurogenic bladder function status of spinal cord injury patients of the present invention; Figure 4 This is a graph showing the changing trend of urine leakage point pressure in different electroacupuncture treatment groups in the evaluation system for neurogenic bladder function in patients with spinal cord injury of the present invention; Figure 5This is a graph showing the changing trend of the maximum bladder capacity of different electroacupuncture treatment groups in the evaluation system for the neurogenic bladder function status of spinal cord injury patients of the present invention; Figure 6 A graph showing a trend of changes in urination time intervals in different electroacupuncture treatment groups in the evaluation system for neurogenic bladder function in patients with spinal cord injury according to the present invention; Figure 7 This is a structural diagram of the evaluation system for the functional status of neurogenic bladder in patients with spinal cord injury according to the present invention. DETAILED DESCRIPTION

[0017] Specific embodiments of the present invention will be described in detail below. It should be noted that the embodiments described herein are for illustrative purposes only and are not intended to limit the present invention. In the following description, numerous specific details are set forth to provide a thorough understanding of the present invention. However, it will be apparent to one of ordinary skill in the art that these specific details are not necessarily required to practice the present invention. In other instances, well-known circuits, software, or methods are not specifically described to avoid obscuring the present invention.

[0018] Throughout this specification, references to "one embodiment," "an embodiment," "an example," or "an example" mean that a particular feature, structure, or characteristic described in connection with the embodiment or example is included in at least one embodiment of the present invention. Therefore, appearances of the phrases "in one embodiment," "in an embodiment," "an example," or "an example" in various places throughout this specification are not necessarily all referring to the same embodiment or example. Furthermore, the particular features, structures, or characteristics may be combined in any suitable combinations and / or subcombinations in one or more embodiments or examples. Furthermore, those of ordinary skill in the art will appreciate that the figures provided herein are for illustrative purposes only and are not necessarily drawn to scale.

[0019] See Figure 1 In order to accurately assess the bladder function of patients with spinal cord injury and develop more scientific and efficient treatment plans for different patients, the present invention proposes a system for assessing the functional status of neurogenic bladder. The system can optimize the processing of relevant test data of patients and output dynamic evaluation results and tissue analysis results. Based on the above results, it provides reference and analysis indicators for the treatment effect, thereby ensuring the effectiveness and pertinence of the patient's treatment plan. The present invention provides an assessment system for the functional status of neurogenic bladder in patients with spinal cord injury. The above-mentioned assessment system for the functional status of neurogenic bladder in patients with spinal cord injury mainly includes the following steps: A system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury includes: a basic information acquisition module, a bladder function dynamics examination and evaluation module, a bladder tissue detection and analysis module, and a bladder function status evaluation module.

[0020] S1. Obtain basic information of patients with spinal cord injury based on the basic information collection module. The specific implementation steps and related contents are as follows: To obtain basic information about spinal cord injury patients, this embodiment uses a basic information collection module to collect basic information about the patients. This module system can comprehensively collect and analyze information such as the patient's medical history, physical condition, and bladder log, laying a solid data foundation for subsequent neurogenic bladder function assessment.

[0021] 1. Collecting the patient's medical history: To fully understand the patient's history of genetic and congenital diseases, as well as whether they have diabetes or infectious diseases, the examples provide a detailed understanding of the patient's trauma and surgical history. Attention is also paid to whether the patient has unhealthy lifestyle habits such as smoking and excessive drinking. Further information on whether the patient experiences constipation, fecal incontinence, and sexual dysfunction is collected to facilitate subsequent understanding and analysis of the onset of the patient's bladder disorder, the specific type, and the urination method used.

[0022] 2. Physical examination of the patient: In this embodiment, a comprehensive physical examination is performed on the patient, including but not limited to basic conditions such as the patient's mental state, clarity of consciousness, cognitive ability, and vital signs. At the same time, a urinary and reproductive system examination is performed, including but not limited to a comprehensive assessment of the abdomen, waist, pelvis, and reproductive organs. In addition, a further neurological examination is required to record the patient's sensory and motor function status in detail, and to test the sensory function and nerve reflexes of the damaged area.

[0023] 3. Create a bladder log: A bladder log is set up in the basic information collection module to record the daily urination of different patients, including but not limited to key information such as the patient's urination time, urine volume, and urination method. The above bladder log not only helps to accurately evaluate the patient's bladder dysfunction in the future, but also provides objective and reliable information for the assessment of neurogenic bladder function.

[0024] Furthermore, the method for obtaining the patient's basic information in this embodiment is merely an optional condition of the present invention. In one or more other embodiments, the method for obtaining the basic information may be replaced according to the patient's actual situation and the evaluation requirements of the bladder function status. In this embodiment, adjusting the method for obtaining the basic information according to the patient's actual situation can ensure that the collected information is more consistent with the patient's individual characteristics, thereby more accurately reflecting the patient's bladder function status, improving the pertinence and practicality of the evaluation system, and helping to formulate personalized treatment plans for different patients.

[0025] S2. Obtain urodynamic examination information of the patient with spinal cord injury using the bladder function dynamics examination and evaluation module. The bladder function dynamics examination and evaluation module combines the urodynamic examination information and basic information to obtain bladder dynamics evaluation results of the patient with spinal cord injury. The specific implementation content is as follows: In an optional embodiment, the bladder function dynamics examination and evaluation module is provided with advanced medical means to obtain the patient's initial detrusor electromyography information.

[0026] The methods for obtaining initial detrusor electromyography information include ultrasound, CT, MRI and other technologies. The above technologies can comprehensively and deeply evaluate the morphology and functional status of the upper urinary tract, such as the kidneys and ureters. Through relevant examination processes, the structural information of the patient's urinary tract system can be obtained, providing technical support for functional status evaluation and treatment plan optimization.

[0027] In addition, surface electromyography technology is used to measure the coordination between the patient's detrusor muscle and urethral sphincter during urine storage and urination. The above detection technology can monitor and record the electrical activity information of the muscles in real time, providing more and more accurate information for bladder function analysis.

[0028] The detrusor electromyography (EMG) procedure requires a series of patient preparations. First, the patient should avoid substances that may affect urination, such as diuretics and caffeine, to ensure accurate test results. Second, the patient should maintain adequate hydration the night before the test to ensure a full bladder during the test. Furthermore, the patient should thoroughly cleanse their skin and empty their bladder before the test.

[0029] During the examination, electrodes, which may be needle electrodes, are placed in the patient's detrusor muscle area to capture the electrical activity information during detrusor contraction. At the same time, the changing trends of the muscle's electrical activity during relaxation and contraction are observed and recorded, including but not limited to time limit, amplitude, number and other related information. The above information will be converted into a visual waveform graph through the instrument, and then the functional status and coordination of the detrusor muscle will be deeply analyzed based on the waveform graph.

[0030] In order to ensure the accuracy and effectiveness of the patient's waveform diagram, it is necessary to set up a monitoring image processing model in the bladder function dynamics examination and evaluation module.

[0031] In the embodiment, a monitoring image processing model is set based on the basic information and the initial detrusor electromyogram. The monitoring image processing model mainly includes a signal waveform analysis model and a vibration amplitude analysis model. The specific implementation content is as follows: Based on the above basic information and the initial detrusor electromyogram, the electrical signal monitoring time is divided into multiple continuous sub-time intervals, namely the sub-time periods of the embodiment. The above sub-time periods are arranged in chronological order to form a set T and satisfy the following relationship: Where N represents the number of all sub-time periods in the set, which means that a total of N sub-time periods are divided in the entire monitoring time.

[0032] In this embodiment, a signal bandwidth is set for the signal waveform of the sub-time period, represented by h, and a maximum bandwidth value is set for it. Next, we will determine a suitable minimum bandwidth value based on the Doppler sensitivity of the signal under various minimum bandwidth limits. .

[0033] The frequency modulation slope of each sub-time period is calculated based on the signal bandwidth of each sub-time period and the pulse width of a single signal. The above frequency modulation slope needs to follow certain mathematical and physical relationships and satisfy the following relationship:

[0034] in, Indicates the signal frequency modulation slope in different sub-time periods, Indicates the signal bandwidth of different sub-time periods, Indicates the pulse width of a single signal.

[0035] Based on this, the signal waveforms of different sub-time periods can be further analyzed, and the above signal waveform analysis model satisfies the following relationship:

[0036] in, Represents the signal waveforms of different sub-time periods, Indicates the center frequency of the signal waveform, Indicates the sampling time corresponding to different sub-time periods, Indicates the signal frequency modulation slope in different sub-time periods, Indicates the pulse width of a single signal, Parameters indicating the effect of needle electrode treatment on signal pulse width, express The initial phase angle of the sub-time period.

[0037] The signal waveforms in different sub-time periods refer to the specific signal waveforms exhibited within each sub-time period after the entire monitoring time is divided into multiple consecutive sub-time periods. The signal waveforms in different time intervals vary due to parameters such as time, frequency, and amplitude, reflecting the dynamic characteristics of the signal within different time periods. Dividing a continuous signal into multiple sub-time periods for analysis and processing during the signal processing process can better capture the signal's detailed characteristics, improve signal processing efficiency, and facilitate the visualization and analysis of subsequent waveform graphs.

[0038] The center frequency of a signal waveform usually refers to the frequency at which the signal energy is strongest in the spectrum graph and represents the main characteristics of the signal.

[0039] The sampling time corresponding to different sub-time periods refers to the specific time point or time length of signal sampling in each sub-time period after the monitoring time is divided into multiple consecutive sub-time periods. During signal processing or data acquisition, the sampling time determines the frequency of signal acquisition, thereby affecting the accuracy of subsequent signal analysis and processing. To ensure the effectiveness of signal sampling, it is necessary to set the appropriate sampling time point and time length in each sub-time period based on the characteristics and requirements of the signal.

[0040] The signal FM slope in different sub-time periods refers to the rate or degree of change of the signal frequency over time in each sub-time period after the signal is divided into multiple consecutive sub-time periods during the monitoring time. The above FM slope describes how the signal frequency increases or decreases linearly within a specific time period and is an important parameter in signal characteristic analysis.

[0041] The pulse width of a single signal refers to the duration of a specific state in the pulse signal, which plays an important role in system performance and stability.

[0042] The parameters affecting the signal pulse width of the needle electrode treatment plan refer to the various factors or conditions that affect the signal pulse width when using needle electrodes for electrical stimulation treatment, including but not limited to waveform, amplitude, frequency, duration, electrode configuration, and treatment position. Relevant factors need to be comprehensively considered based on the patient's specific situation and treatment needs to select appropriate pulse width and treatment parameters.

[0043] The initial phase angle for each sub-time period refers to the phase angle of the electrical signal or vibration waveform at the beginning of each consecutive sub-time period after the monitoring time is divided into multiple sub-time periods. The initial phase angle, also known as the initial phase or initial phase angle, determines the waveform's subsequent behavior and characteristics. It describes the phase offset of the signal or waveform at a specific point in time, such as the start of each sub-time period, relative to a reference point. This reference point can be the zero point of a sine wave or a specific phase point.

[0044] Based on this analysis of the corresponding vibration amplitude within the monitoring time, the above vibration amplitude analysis model satisfies the following relationship:

[0045] in, Indicates the vibration amplitude corresponding to the monitoring time, Indicates the number of sub-time periods within the monitoring time. express The vibration peak value of the electrical signal in the sub-time period, Indicates the influence coefficient of needle electrode treatment program on electrical signals, express The average angular frequency of the electrical signal in the sub-time period, express The weight coefficient of the electrical signal in the sub-time period, express The initial phase angle of the sub-time period.

[0046] The vibration amplitude corresponding to the monitoring time refers to the maximum distance that the vibrating body deviates from its equilibrium position within a specific monitoring period. The above distance is usually expressed as a peak value or peak-to-peak value. The vibration amplitude is an important parameter that describes the vibration intensity or vibration energy. It reflects the magnitude of the signal vibration amplitude within a given time. By monitoring the vibration amplitude in different time periods, vibration anomalies can be discovered in a timely manner, providing an important basis for equipment maintenance and management.

[0047] The peak vibration value of an electrical signal in different sub-time periods refers to the maximum positive or negative value that the electrical signal can reach within each sub-time period after the entire monitoring time is divided into multiple consecutive sub-time periods. This peak value reflects the amplitude of the electrical signal within each time period and is an important parameter for describing the dynamic characteristics of electrical signals. During electrical signal processing, the peak vibration value (or peak value) can be used to describe the signal's strength, amplitude, and changes within a specific time period. This helps to gain a deeper understanding of the dynamic behavior of electrical signals and provides a reference for subsequent signal processing and fault diagnosis.

[0048] In practical applications, the impact of needle electrode treatment on electrical signals is a relatively complex and multi-dimensional concept involving multiple parameters and factors. When using needle electrodes for electrical stimulation therapy, the treatment plan affects factors such as the amplitude, frequency, and phase of the electrical signal, which are quantitatively described by coefficients or parameters in the embodiments.

[0049] The average angular frequency of the electrical signal in different sub-time periods refers to the average value of the angular frequency of the electrical signal in each sub-time period after the monitoring time is divided into multiple consecutive sub-time periods. Angular frequency, also known as angular velocity, is a physical quantity that describes the speed of signal change. In a sinusoidal signal, there is a direct relationship between angular frequency and frequency, that is, angular frequency is equal to the frequency. times, the specific relationship is as follows: .

[0050] The weight coefficient of the electrical signals in different sub-time periods refers to a numerical value assigned to each sub-time period after the entire monitoring time is divided into multiple consecutive sub-time periods in order to reflect the importance or influence of the electrical signals in different sub-time periods. The above weight coefficient can be used in subsequent signal processing, data analysis or decision-making processes to perform weighted processing on the electrical signals in the sub-time periods, which can more accurately reflect the overall characteristics and changing trends of the signals.

[0051] Then, the bladder function dynamics examination and evaluation module processes the initial detrusor electromyogram using the monitoring image processing model and obtains the patient's detrusor electromyogram information.

[0052] In the embodiment, the bladder function dynamics examination and evaluation module processes the initial detrusor electromyogram through a signal waveform analysis model and a vibration amplitude analysis model, and obtains the patient's detrusor electromyogram information.

[0053] The signal waveform is adjusted and optimized based on the signal waveforms of different sub-time periods and the vibration amplitude corresponding to the monitoring time to obtain the target signal waveform result of the embodiment.

[0054] During the entire time period of electrical signal monitoring, the time is divided into several sub-time periods, and the signal waveform is adjusted and optimized for each sub-time period. After the adjustment, a signal waveform matrix can be obtained, that is, the sub-time period signal waveform matrix of the embodiment, which corresponds to the monitoring segment information of different time intervals.

[0055] Specifically, for the sub-time periods, there is a signal waveform matrix ; For the sub-time periods, we have a signal waveform matrix ; and so on, until the sub-time periods, and obtain the signal waveform matrix The above sub-time period signal waveform matrices together constitute the signal waveform matrix set within the monitoring time, and the signal waveform matrix set is expressed as .

[0056] Therefore, a set composed of multiple sub-time period signal waveform matrices comprehensively reflects the changes in the signal waveform over time during the monitoring time. By adjusting and optimizing the signal waveform of each sub-time period, the desired target signal waveform result can be obtained, that is, the patient's detrusor electromyography information can be obtained.

[0057] The signal waveform matrix composed of signal waveform matrices of different sub-time periods satisfies the following relationship:

[0058] in, Represents the signal waveform matrix set within the electrical signal monitoring time, express The signal waveform matrix corresponding to the sub-time period, express The signal waveform matrix corresponding to the sub-time period, express Signal waveform matrix corresponding to the sub-time period.

[0059] Furthermore, the target vibration waveform is compared and analyzed with the actual vibration signal waveform, and the specific contents are as follows: Target vibration waveform see Figure 2 , which presents an ideal and regular vibration form, in which parameters such as amplitude, frequency and phase are constant, so the waveform presents a simple and smooth change curve.

[0060] However, in actual applications, the waveform of the vibration signal is more chaotic and complex than the target vibration waveform. By analyzing the initial detrusor EMG based on signal waveform analysis models, vibration amplitude analysis models, and related basic concepts, and selecting a specific point as a phase reference, we can determine the relative positional relationship between each transient value on the vibration waveform and each point on the rotor. This allows for a deeper understanding of the characteristics and patterns of the actual vibration signal. Furthermore, this approach further reveals the intrinsic connections and influencing relationships between the various components of the detrusor EMG signal and frequency.

[0061] When processing the initial detrusor EMG vibration amplitude, the peak-to-peak value can be used. The peak-to-peak value refers to the difference between the maximum and minimum values in the vibration waveform, which can effectively represent the maximum amplitude of the vibration. For the detrusor EMG vibration waveform before processing, please refer to Figure 3 .

[0062] In an optional embodiment, urodynamic examination information of a spinal cord injury patient is analyzed based on detrusor electromyography information and basic information. The urodynamic examination information of this embodiment mainly includes leak point pressure data, urination bladder capacity data, and urination time interval data.

[0063] The urodynamic examination results of the spinal cord injury patient after treatment are obtained by analyzing the detrusor electromyography information and the patient's basic information. In the embodiment, the urodynamic data includes the leak point pressure, the bladder capacity during urination, and the time interval between urination.

[0064] In order to obtain the above urodynamic data, an IV urodynamic meter was used as the main detection tool. During the specific operation, an 8F double-lumen catheter was used, which was inserted through the urethra and connected to the bladder. The pressure measuring medium of the catheter was isotonic saline, and the temperature was maintained at approximately 37°C. Saline was injected at a rate of 60ml / min. During this process, the patient's residual urine volume, bladder pressure, detrusor electromyography, detrusor pressure, and urine flow rate, etc. were measured and recorded in a timely manner. The interpretation and analysis of the above indicators strictly followed the relevant standards of the International Continence Association.

[0065] In the analysis of bladder pressure, the effects of electrical stimulation of different frequencies on the leak point pressure, maximum bladder capacity and urination time interval of rats were analyzed in particular, and the relevant data were used as key evaluation indicators for dynamic examination and analysis.

[0066] During the index detection process, a TSD 104A pressure sensor was used, and an experimental rat model was set up as the experimental detection object. Specifically, the pressure sensor was connected to the bladder of the rat model, and a 0.9% sterile methylene blue sodium chloride solution was injected at a rate of 12mL / h through a microinjection pump and a dural medical catheter. At the same time, the experimental animal physiological data acquisition system AcqKnowledge 5.0-DA 100C channel was used to collect the bladder urodynamic data of the rat model. During the experiment, the rat model was anesthetized to ensure that its bladder reflex was normal and its urine was emptied. Then, the dural catheter was inserted into the bladder of the rat model, and the data acquisition system was started to record the corresponding urodynamic data.

[0067] Based on statistical analysis methods, the mean and standard deviation were used in the examples. To represent the kinetic examination data, SPSS26.0 software was used for statistical analysis. The kinetic examination data were analyzed by paired Test method: One-way analysis of variance was used to compare the examination data among multiple groups. When the P value was less than 0.05, the difference was considered statistically significant.

[0068] Finally, based on the monitoring image processing model, data monitoring technology and rat model, leak point pressure data, bladder capacity data during urination, urination time interval data and detrusor electromyography information were obtained. The above data provided data support for further analysis and evaluation of the urodynamic performance of patients with spinal cord injury.

[0069] Next, the bladder function dynamics examination and evaluation module combines the leak point pressure data, urination bladder capacity data, urination time interval data and basic information for analysis to obtain the bladder dynamics evaluation results of patients with spinal cord injury.

[0070] In an optional embodiment, in order to analyze the effects of different electroacupuncture treatment regimens on bladder urodynamic parameters in rats with stress urinary incontinence, a rat model, a normal control group and electroacupuncture treatment groups of different frequencies were set up, wherein the treatment groups included Group A, Group B and Group C.

[0071] Comparison of bladder function dynamics data before and after electroacupuncture treatment revealed no statistically significant differences in baseline bladder pressure between the rat models (P>0.05). However, before electroacupuncture treatment, the leak point pressure, maximum bladder capacity, and urination interval of the control group rats were significantly lower than those of the treated group (P<0.01). These results strongly confirm the success, feasibility, and scientific validity of the rat model.

[0072] Furthermore, after electroacupuncture treatment, urodynamic parameters in the rat models in the electroacupuncture treatment group maintained a significant downward trend compared to the normal control group (P<0.01). Further comparison of the data from rat models in groups A, B, and C, which received different frequencies of electroacupuncture within the electrode treatment group, revealed that leak point pressure, maximum bladder capacity, and urination interval in the rat models in these treatment groups all showed a significant upward trend (P<0.05 or P<0.01), indicating that electroacupuncture treatment has a positive effect on improving urodynamic parameters.

[0073] In addition, data comparisons were conducted between different treatment groups. The results showed that after electroacupuncture treatment, the leak point pressure, maximum bladder capacity, and urination interval of the rat models in Groups A, B, and C were significantly improved compared with those before treatment (P<0.05). For relevant comparative data, please see Table 1.

[0074] Table 1 Comparison of urodynamic examination information

[0075] The urodynamic examination data in Table 1 reveal the effects of different frequency electroacupuncture treatment regimens on rat bladder urodynamic parameters, providing a strong experimental basis for further exploring the potential mechanism and practical application of electroacupuncture treatment regimens.

[0076] The leakage point pressure of rat models in different electroacupuncture schemes was analyzed based on urodynamic examination data.

[0077] Urodynamic examination data after electroacupuncture showed significant changes in the rat model's leak point pressure. Specifically, compared with the low-frequency electroacupuncture group A, the rat models in groups B and C, which received medium- and high-frequency electroacupuncture, showed significant increases in leak point pressure (P<0.01), indicating that medium- and high-frequency electroacupuncture is effective in increasing the leak point pressure in rat models.

[0078] Furthermore, a comparison of the rat models of EA Group B (medium-frequency EA treatment) and EA Group C (high-frequency EA treatment) revealed that the leak point pressure of the rat model in EA Group C was significantly higher than that in EA Group B (P<0.05). The above results further confirmed that the effect of increasing the EA frequency during treatment was more significant. In addition, based on the above information, a graph showing the change trend of leak point pressure after EA treatment of different frequencies is depicted. For details, please see Figure 4 .

[0079] The maximum bladder capacity of the rat model in different electroacupuncture schemes was analyzed based on urodynamic examination data.

[0080] The researchers further compared the effects of different electroacupuncture treatment regimens on the maximum bladder capacity of the rat model. The results showed that compared with the low-frequency electroacupuncture group A, the high-frequency electroacupuncture group C showed a significant increase in maximum bladder capacity (P<0.01), indicating that the high-frequency electroacupuncture regimen is significantly effective in increasing maximum bladder capacity.

[0081] However, a comparison between electroacupuncture group A and electroacupuncture group B showed that the maximum bladder capacity of the rat model did not show a statistically significant difference (P>0.05), which means that the effect of medium-frequency electroacupuncture treatment (electroacupuncture group B) in improving the maximum bladder capacity was not as obvious as that of high-frequency electroacupuncture treatment (electroacupuncture group C).

[0082] Furthermore, a comparison of the rat models in EA Group B and EA Group C revealed that the maximum bladder capacity of the rat model in EA Group C also increased significantly compared with that in EA Group B (P<0.05), further reinforcing the advantage of high-frequency EA in increasing maximum bladder capacity. A schematic diagram of the changing trend of maximum bladder capacity in different EA treatment regimens is also presented. For details, please refer to Figure 5 .

[0083] The urination time intervals of rat models in different electroacupuncture schemes were analyzed based on urodynamic examination data.

[0084] Further evaluation of the effects of different EA treatment regimens on the urination interval in rat models revealed a significant trend toward longer urination intervals in both EA Group B (medium-frequency EA) and EA Group C (high-frequency EA) compared to low-frequency EA Group A (P < 0.05). Further findings indicate that both medium-frequency and high-frequency EA treatments effectively increase the urination interval in rats.

[0085] Further comparison of the rat models in EA Group B and EA Group C revealed that the urination interval of the rat model in EA Group C was significantly prolonged compared to that in EA Group B (P<0.01). This significant difference indicates that high-frequency EA treatment is more effective than medium-frequency EA treatment in improving the urination interval of the rat model. To visually compare the urination interval of the rat model after EA treatment, the following examples show the changing trend of urination interval in different EA treatment regimens. For details, please refer to Figure 6 .

[0086] Based on the detrusor electromyography information, the patient's basic information, and the urodynamic examination results including detailed data such as leak point pressure, urination bladder capacity, and urination interval, the bladder dynamics evaluation results of patients with spinal cord injury can be comprehensively obtained, which is helpful for the subsequent comprehensive assessment of the bladder dynamics status of patients with spinal cord injury.

[0087] Furthermore, the analysis steps and related methods of the bladder dynamics evaluation results in this embodiment are merely optional conditions of the present invention. In one or more other embodiments, the analysis steps and methods of the dynamics evaluation results can be adjusted and optimized based on the evaluation requirements of the neurogenic bladder functional status and the actual conditions of the experimental model. Adjusting and optimizing the analysis steps and methods of the dynamics evaluation results in the embodiments will help promote the continuous deepening and optimization of the neurogenic bladder functional status evaluation system and provide more scientific basis and technical support for clinical treatment and rehabilitation.

[0088] S3. Obtain tissue detection information of the spinal cord injury patient through the bladder tissue detection and analysis module. The bladder tissue detection and analysis module obtains bladder tissue analysis results of the spinal cord injury patient based on the tissue detection information and basic information. The specific implementation content is as follows: First, spinal cord injury tissue detection data can be obtained from the bladder tissue of the rat model, which mainly includes the apoptosis status of detrusor muscle cells, fibrosis details including collagen fiber content and type I / III collagen ratio, and the expression of detrusor M receptor mRNA.

[0089] Then, the apoptosis status of detrusor muscle cells was deeply analyzed using the apoptosis data and its basic information. At the same time, the composition ratio of collagen fibers in the detrusor muscle tissue was investigated based on the fibrosis information and its basic data. In addition, the relative expression level of detrusor M receptor mRNA was further evaluated in combination with the expression information of detrusor M receptor mRNA and its basic data.

[0090] By comprehensively organizing and analyzing the above-mentioned apoptosis status, collagen fiber ratio and M receptor mRNA expression level, we can obtain the bladder tissue analysis results of patients with spinal cord injury.

[0091] In an optional embodiment, the degree of apoptosis and fibrosis of detrusor muscle cells are evaluated using a series of biological and medical experimental procedures, as follows: Sample acquisition: Detrusor muscle tissue samples were collected from rat models as the basis for the study.

[0092] The TUNEL method, an in situ apoptosis detection method based on terminal deoxynucleotidyl transferase activity, was used to detect apoptotic cells. Flow cytometry or immunohistochemistry analysis was combined with this method to further identify and quantify apoptotic cells in the detrusor muscle tissue of the rat model.

[0093] In the data analysis phase, the test results are analyzed and interpreted to calculate the proportion of apoptotic cells in the total number of cells, thereby accurately evaluating the degree of apoptosis of detrusor muscle cells.

[0094] In the embodiment, the fibrosis assessment mainly analyzes the collagen fiber content. The degree of fibrosis can be evaluated by measuring the collagen fiber content in the tissue sample. For detrusor muscle tissue, the specific steps for evaluating the collagen fiber content are as follows: Sample pretreatment involves sectioning, staining, and other necessary processing steps on rat model detrusor muscle tissue samples to facilitate detailed observation under a microscope.

[0095] The collagen fibers can be stained using Masson trichrome staining or picrosirius red staining to make the collagen fibers clearly visible in the tissue.

[0096] The image analysis process mainly relies on computer image processing technology and related systems to analyze the stained tissue sections, so as to accurately calculate the area or proportion occupied by collagen fibers.

[0097] The data interpretation stage is mainly based on the image analysis results to determine the exact content of collagen fibers in the detrusor muscle tissue.

[0098] The calculation of type I / III collagen ratio is as follows: Type I and type III collagen are important types of collagen that constitute tissues. Their ratio has a crucial impact on the structure and function of tissues. The specific steps for calculating the type I / III collagen ratio are as follows.

[0099] The sample processing and staining process also requires appropriate processing and staining of the detrusor muscle tissue samples to clearly distinguish type I and type III collagen under a microscope.

[0100] Collagen type identification technology mainly uses a polarized light microscope to observe stained tissue sections and accurately distinguish type I and type III collagen based on the refractive index and color characteristics of collagen fibers.

[0101] In the counting and ratio determination stage, the identified type I and type III collagens are accurately counted, and the ratio of type I and type III collagen is calculated accordingly.

[0102] On the other hand, changes in indicators such as detrusor cell apoptosis, fibrosis degree, and type I / III collagen ratio are closely related to other disease conditions of the patient, including but not limited to prostate hyperplasia, bladder dysfunction, etc. Therefore, when conducting relevant tests, the patient's clinical symptoms and other examination results should be comprehensively considered to make a more accurate diagnosis and judgment.

[0103] In another optional embodiment, the steps for obtaining the detrusor M receptor mRNA expression information and related implementation contents are as follows: 1. Preparation Stage Sample acquisition: Detrusor muscle tissue samples are collected from rat models or clinical patients to ensure the integrity of the sample and maintain its freshness, which can effectively prevent RNA degradation.

[0104] Reagent and equipment preparation: Prepare all kinds of reagents required for RNA extraction, reverse transcription, and PCR reaction, as well as core experimental equipment such as fluorescence quantitative PCR instrument and electrophoresis device.

[0105] 2. RNA Extraction and Purification Tissue disruption: Use a homogenizer or tissue grinding device to break the detrusor muscle tissue sample into a homogenate, laying the foundation for the subsequent efficient extraction of RNA.

[0106] RNA extraction: Total RNA is extracted from tissue using RNA extraction reagents such as Trizol. During this process, a strict RNase-free environment must be maintained to ensure the integrity of the RNA.

[0107] RNA purification: Using an RNA purification kit to further remove impurities such as DNA and protein from RNA helps improve the purity of the RNA and provide a high-quality template for subsequent reverse transcription reactions.

[0108] 3. Reverse Transcription Process Reverse transcription reaction: Use the purified RNA as a template and reverse transcribe it using reverse transcriptase and specific primers to generate the corresponding cDNA.

[0109] cDNA amplification: During reverse transcription, the cDNA amplification step can be performed to provide sufficient template for subsequent PCR reactions.

[0110] IV. PCR Amplification and Product Detection Primer design: Based on the gene sequence of the M receptor, highly specific PCR primers were designed.

[0111] PCR amplification: Using the cDNA obtained by reverse transcription as a template, primers, dNTPs, PCR buffer and other necessary components are added to carry out the PCR amplification reaction. The reaction conditions need to be fine-tuned according to the characteristics of the primers and experimental requirements.

[0112] Product verification: Detect PCR products by electrophoresis to observe whether the expected specific bands appear to verify the success of PCR amplification and the expression of M receptor mRNA.

[0113] 5. Fluorescence quantitative PCR analysis Fluorescent labeling: Add fluorescently labeled primers or probes to the PCR reaction system to achieve real-time monitoring of PCR product generation.

[0114] Fluorescence quantitative PCR: PCR reactions are performed on a fluorescence quantitative PCR instrument, and changes in the fluorescence signal are recorded in real time. This change is directly related to the amount of PCR product generated.

[0115] Data analysis: The data analysis software provided with the fluorescence quantitative PCR instrument was used to deeply analyze the experimental results and obtain the absolute and relative expression levels of M receptor mRNA.

[0116] Based on the above implementation process, the expression level of M receptor mRNA in the detrusor muscle can be detected, which is of great significance for subsequently revealing the physiological function of the detrusor muscle, exploring the pathogenesis and treatment strategies of related diseases.

[0117] Furthermore, the method for obtaining the bladder tissue analysis results in this embodiment is merely an optional condition of the present invention. In one or more other embodiments, the method for obtaining the bladder tissue analysis results can be changed according to the actual situation of the spinal cord injury patient and the specific condition of the bladder tissue. Based on this, more accurate and personalized bladder tissue analysis results can be provided, thereby obtaining more accurate bladder function status assessment results.

[0118] S4. The bladder function status assessment module comprehensively evaluates the neurogenic bladder function status of patients with spinal cord injury based on basic information, bladder dynamics evaluation results, and bladder tissue analysis results. The specific implementation content is as follows: First, it is necessary to introduce historical assessment records of the functional status of neurogenic bladder.

[0119] The bladder function status assessment module comprehensively evaluates the neurogenic bladder function status of patients with spinal cord injury based on basic information, leak point pressure data, urination bladder capacity data, urination interval data, apoptosis degree, proportion and relative expression level, and obtains comprehensive assessment results; Next, the above comprehensive evaluation results are compared with the historical evaluation record information, and the treatment plan for the patient's neurogenic bladder after spinal cord injury is adjusted and optimized based on the comparison results.

[0120] In an optional embodiment, a comprehensive evaluation system is constructed in the bladder function status evaluation module, which aims to comprehensively evaluate the neurogenic bladder function status of patients with spinal cord injury based on basic information, bladder dynamics evaluation results, and bladder tissue analysis results. The specific implementation content of the above module is as follows: First, to more scientifically assess patients' bladder function, we introduced historical assessment records of neurogenic bladder function. This information records bladder function status for different patients at different time points, providing a reference basis and evaluation standard for the assessment system of neurogenic bladder function in patients with spinal cord injury.

[0121] Next, the bladder function status assessment module makes full use of multiple data sources, including basic information such as the patient's age, gender, and degree of spinal cord injury, key indicators for bladder dynamics evaluation, such as leak point pressure data, urination bladder capacity data, urination time interval data, etc., and detailed results of bladder tissue analysis, such as the degree of apoptosis of detrusor muscle cells, the proportion of collagen fibers, and the relative expression level of M receptor mRNA. Based on the above multi-dimensional data, a comprehensive analysis and accurate assessment of the patient's bladder function status are carried out.

[0122] On this basis, the bladder function status assessment module uses advanced algorithms and models to conduct a comprehensive analysis of relevant data, thereby obtaining a comprehensive assessment of the neurogenic bladder function status of patients with spinal cord injury. The above assessment results not only reflect the patient's current bladder function status, but also reveal its potential development trends.

[0123] Finally, the comprehensive assessment results are compared with the patient's historical assessment records. By comparing the patient's bladder function status at different time points, we can accurately analyze the impact of the current electrode treatment plan on the patient's bladder function and the direction of improvement or deterioration of bladder function in the future. Based on the comparison results and analysis information, the patient's neurogenic bladder treatment plan after spinal cord injury can be further adjusted and optimized to ensure the targeted and effective treatment plan, thereby helping the patient better restore bladder function and improving the feasibility and effectiveness of the disease treatment plan.

[0124] See Figure 7 In an optional embodiment, the present invention further provides a system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury. The system comprises a basic information acquisition module, a bladder function dynamics examination and evaluation module, a bladder tissue detection and analysis module, and a bladder function status evaluation module. These basic information acquisition module, bladder function dynamics examination and evaluation module, bladder tissue detection and analysis module, and bladder function status evaluation module are interconnected to implement the specific steps of the embodiments of the system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury provided by the present invention. The system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury of the present invention is structurally complete, objective, and stable, enhancing the overall applicability and practical application capabilities of the present invention.

[0125] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the above embodiments, or make equivalent replacements for some or all of the technical features therein. These modifications or replacements do not deviate the essence of the corresponding technical solutions from the scope of the technical solutions of the embodiments of the present invention, and they should all be included in the scope of the claims and description of the present invention.

Claims

1. A system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury, characterized in that: The evaluation system for the neurogenic bladder function status of patients with spinal cord injury includes: a basic information acquisition module, a bladder function dynamics examination and evaluation module, a bladder tissue detection and analysis module, and a bladder function status evaluation module; Obtaining basic information of the spinal cord injury patient based on the basic information acquisition module; The bladder function dynamics examination and evaluation module is used to obtain urodynamic examination information of the patient with spinal cord injury, and the bladder function dynamics examination and evaluation module combines the urodynamic examination information and the basic information to obtain a bladder dynamics evaluation result of the patient with spinal cord injury; The bladder tissue detection and analysis module obtains tissue detection information of the patient with spinal cord injury, and the bladder tissue detection and analysis module obtains bladder tissue analysis results of the patient with spinal cord injury based on the tissue detection information and the basic information; The bladder function status assessment module comprehensively assesses the neurogenic bladder function status of the spinal cord injury patient based on the basic information, the bladder dynamics evaluation results, and the bladder tissue analysis results.

2. The system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury according to claim 1, characterized in that: The method of obtaining urodynamic examination information of a patient with spinal cord injury by using the bladder function dynamics examination and evaluation module includes: Obtaining the patient's detrusor electromyogram information using the bladder function dynamics examination and evaluation module; The urodynamic examination information of the spinal cord injury patient is analyzed based on the detrusor electromyography information and the basic information, where the urodynamic examination information includes leak point pressure data, urination bladder capacity data, and urination time interval data.

3. The system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury according to claim 2, characterized in that: The method of obtaining the patient's detrusor electromyogram information by using the bladder function dynamics examination and evaluation module includes: Setting a monitoring image processing model in the bladder function dynamics examination and evaluation module; The bladder function dynamics examination and evaluation module processes the initial detrusor electromyogram using the monitoring image processing model and obtains the patient's detrusor electromyogram information.

4. The system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury according to claim 3, characterized in that: The bladder function dynamics examination and evaluation module processes the initial detrusor electromyogram using the monitoring image processing model, and obtains the patient's detrusor electromyogram information including: Setting a monitoring image processing model based on the basic information and the initial detrusor electromyogram, wherein the monitoring image processing model includes a signal waveform analysis model and a vibration amplitude analysis model; The bladder function dynamics examination and evaluation module processes the initial detrusor electromyogram through the signal waveform analysis model and the vibration amplitude analysis model, and obtains the patient's detrusor electromyogram information.

5. The system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury according to claim 4, characterized in that: The signal waveform analysis model satisfies the following relationship: ， in, Represents the signal waveforms of different sub-time periods, Indicates the center frequency of the signal waveform, Indicates the sampling time corresponding to different sub-time periods, Indicates the signal frequency modulation slope in different sub-time periods, Indicates the pulse width of a single signal, Parameters indicating the effect of needle electrode treatment on signal pulse width, express The initial phase angle of the sub-time period.

6. The system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury according to claim 4, characterized in that: The vibration amplitude analysis model satisfies the following relationship: ， in, Indicates the vibration amplitude corresponding to the monitoring time, Indicates the number of sub-time periods within the monitoring time. express The vibration peak value of the electrical signal in the sub-time period, Indicates the influence coefficient of needle electrode treatment program on electrical signals, express The average angular frequency of the electrical signal in the sub-time period, express The weight coefficient of the electrical signal in the sub-time period, express The initial phase angle of the sub-time period.

7. The system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury according to claim 4, characterized in that: The bladder function dynamics examination and evaluation module combines the urodynamic examination information and the basic information to obtain the bladder dynamics evaluation results of the spinal cord injury patient, including: The bladder function dynamics examination and evaluation module combines the leak point pressure data, the urination bladder capacity data, the urination time interval data and the basic information for analysis to obtain a bladder dynamics evaluation result for the spinal cord injury patient.

8. The system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury according to claim 1, characterized in that: The obtaining of tissue detection information of a spinal cord injury patient by the bladder tissue detection and analysis module includes: The tissue detection information of the spinal cord injury patient is obtained through the bladder tissue detection and analysis module, and the tissue detection information includes detrusor muscle cell apoptosis data, fibrosis information and detrusor M receptor mRNA expression information of the spinal cord injury patient.

9. The system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury according to claim 8, characterized in that: The bladder tissue detection and analysis module obtains the bladder tissue analysis results of the spinal cord injury patient based on the tissue detection information and the basic information, including: Analyzing the degree of apoptosis of detrusor muscle cells based on the detrusor muscle cell apoptosis data and the basic information; Analyzing the proportion of collagen fibers in the detrusor muscle tissue based on the fibrosis information and the basic information; Analyzing the relative expression level of M receptor mRNA based on the detrusor M receptor mRNA expression information and the basic information; The bladder tissue analysis results of patients with spinal cord injury are obtained by combining the apoptosis degree, the ratio and the relative expression level.

10. The system for evaluating the functional status of neurogenic bladder in patients with spinal cord injury according to claim 9, characterized in that: The bladder function status assessment module comprehensively assesses the neurogenic bladder function status of the spinal cord injury patient based on the basic information, the bladder dynamics evaluation results, and the bladder tissue analysis results, including: Introducing historical assessment and recording of neurogenic bladder functional status; The bladder function status assessment module comprehensively assesses the neurogenic bladder function status of the spinal cord injury patient based on the basic information, the leak point pressure data, the urination bladder capacity data, the urination time interval data, the apoptosis degree, the ratio and the relative expression level, and obtains a comprehensive assessment result; The comprehensive assessment result is compared with the historical assessment record information, and the treatment plan for the patient's neurogenic bladder after spinal cord injury is adjusted and optimized based on the comparison result.

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