Glasses lens supply system, glasses lens supply method, glasses lens design method, glasses lens manufacturing method, and program for glasses lens supply system

Abstract

The present invention provides an eyeglasses lens supply system and a technique related thereto, the eyeglasses lens supply system being provided with: a spectral transmittance setting unit that sets the spectral transmittance of an eyeglasses lens on the basis of a relationship selected from at least one of relationships 1-3; and a share content determination unit that shares the task to achieve the selected relationship by a material A that reduces the transmittance in a predetermined wavelength range S and a material B that reduces the transmittance in another predetermined wavelength range T.

Description

Technical Field

[0001] This invention relates to a supply system for eyeglass lenses, a method for supplying eyeglass lenses, a method for designing eyeglass lenses, a method for manufacturing eyeglass lenses, and a procedure for a supply system for eyeglass lenses. Background Technology

[0002] Non-patent literature 1 discloses research results on symptoms and diseases caused by abnormalities in lens epithelial cells, such as secondary cataracts. It should be noted that secondary cataracts refer to the following:

[0003] Treatment for patients with cataracts after the onset of the disease includes cataract surgery. Generally, the cloudy lens is removed from the incisional lens capsule (ultrasound phacoemulsification), and instead, an intraocular lens is inserted into the lens capsule. The intraocular lens is covered by the partially incisional lens capsule.

[0004] Postoperative complications can occur. One such complication is the proliferation of residual lens epithelial cells and other remnants in the lens capsule, particularly in the space between the posterior surface of the lens (the inner surface of the eye, the surface opposite to the side facing the object in front of the eye) and the lens capsule. This proliferation leads to lens capsule opacification (posterior capsule opacification), which further reduces light transmission into the eye and causes visual impairment; this is known as secondary cataract. In this case, a representative treatment is the removal of the opacity using a YAG laser.

[0005] In Japan, around 2020, approximately 30% of cataract surgeries (lens repair surgeries) were for treating secondary cataracts, which was considered a problem. Furthermore, it was believed that abnormalities in the lens epithelial cells were also related to other lens-related symptoms and diseases.

[0006] Regarding the lens epithelial cells, which are a cause of secondary cataracts, Non-Patent Literature 1 suggests that it is very important to understand what kind of light characteristics are incident on the eyes of an individual (hereinafter referred to as the Subject) in their living environment and whether or how the lens epithelial cells change.

[0007] Based on the above viewpoints, non-patent literature 1 discloses the results of an investigation into the effects of light wavelength and irradiance on lens epithelial cells. The results show that, depending on the wavelength and irradiance of light, lens epithelial cells undergo morphological changes and become irregularly morphological, which in turn reduces their migration ability.

[0008] This survey result is cited as part of non-patent document 1. Figure 1The irradiance (vertical axis: unit W / m²) of each light source (10nm half-width) used in the experiment 2 The graph shows the relationship between wavelength (horizontal axis: unit is nm) and morphological changes and migration abilities of lens epithelial cells. Sunlight is also included as a reference in this graph.

[0009] In non-patent literature 1, it is believed that... Figure 1 In the diagram, a dashed line defines the boundary between small and medium effects, a dashed line defines the boundary between medium and large effects, and a solid line defines the boundary between the presence and absence of cell morphological abnormalities. From... Figure 1 As can be seen, compared with sunlight, light with low irradiance tends to significantly reduce mobility in the 400–520 nm range. Furthermore, the decrease in mobility is more pronounced under short wavelength and high irradiance conditions, thus it is appropriate to design filters that exhibit an exponential correlation.

[0010] Figure 2 From Figure 1 The graph derived from the boundary line represents the shielding characteristics of optical filters that suppress large and middle effects. It is a graph showing the relationship between transmittance (vertical axis: in %) and wavelength (horizontal axis: in nm).

[0011] Existing technical documents

[0012] Non-patent literature

[0013] Non-patent literature 1: Evaluation of the effect of light irradiation in a trauma healing model for the prevention of secondary cataracts (Akira Nishida, Masafumi Otomo, Yuki Tani, Hiromi Miyoshi) (33rd Biological Frontiers Conference of the Japanese Society of Mechanical Engineers (December 17-18, 2022) 1C-09) Summary of the Invention

[0014] The technical problem that the invention aims to solve

[0015] The inventors of this invention have carefully studied Non-Patent Literature 1 and have clarified the following points.

[0016] In non-patent literature 1 disclosed Figure 1 and Figure 2 In this study, the range of irradiance is set only based on the approximate irradiance of sunlight (AM1.5) at the anterior surface of the lens. For the approximate irradiance, the half-width of each bandpass filter is calculated as the wavelength width based on the spectroscopic irradiance of sunlight (AM1.5) at the anterior surface of the lens.

[0017] AM, or air quality, is the ratio of the path of sunlight to that of sunlight incident perpendicularly to the Earth's surface (AM1). For latitudes in Japan, AM1.5 is usually used.

[0018] On the other hand, the intensity of light radiation (irradiance) varies greatly depending on the region on Earth. For example, simply put, as shown on the following website (https: / / documents1.worldbank.org / curated / en / 529431592893043403 / pdf / Global-Solar-Atlas-2-0-Technical-Report.pdf), solar irradiance varies greatly around the world.

[0019] Furthermore, for example, even within the United States of America, Florida's annual average solar radiation is 1.25 times that of Massachusetts (https: / / www.nrel.gov / gis / solar-resource-maps.html).

[0020] In addition, in areas with abundant snow, the reflection of short-wavelength light caused by snow is about 2 to 3 times that caused by soil (https: / / pdfs.semanticscholar.org / 5fa8 / 86d72e792fdd0c5e8818e3025b3354db4372.pdf).

[0021] Another new perspective obtained by the inventors of this invention is that the spectral transmittance of the wearer's eye varies greatly depending on the wearer. For example, when an intraocular lens has already been implanted within the wearer's lens capsule, the spectral transmittance of the intraocular lens needs to be considered when reconstructing the aforementioned structure. Figure 2 .

[0022] It should be noted that the following content is also recorded in Non-Patent Document 1.

[0023] • It was reported that when porcine retinal pigment epithelial cells were exposed to light at irradiances of 415–455 nm, similar to sunlight, cell viability decreased.

[0024] • This region corresponds to the range of the large effect obtained in this study.

[0025] Therefore, it is believed that the wavelength-irradiance band with a large effect has an adverse effect on retinal pigment epithelial cells and is an area that should be shielded.

[0026] Based on the above, it is also newly known that this view can be applied to other eye-related cells besides lens epithelial cells (hereinafter referred to as ocular cells, and specific examples of ocular cells will be explained).

[0027] The inventors of this invention have set the following as a first-stage objective in an embodiment of this invention: that is, to set the supply of spectacle lenses that have been pre-designed to counteract phototoxicity to eye cells as a first-stage objective.

[0028] The inventors of this invention further investigated the issues described above as the first stage. As a result, the following issues were discovered as the second stage.

[0029] Although eyeglass lenses that take precautions against phototoxicity to eye cells are being supplied, there is still room for research into how to supply such lenses, as a practical issue.

[0030] Specifically, it is necessary to address the inventory of lens substrates or functional film materials. For example, when supplying eyeglass lenses that have been designed to counteract phototoxicity to customers residing in certain areas, if there is no stock of the material for the functional film that provides the filtering properties required for the countermeasures, such eyeglass lenses cannot be supplied to those customers.

[0031] Of course, while having sufficient inventory of lens substrates and functional film materials can prevent such unpredictable situations, it increases the inventory management burden for the suppliers (manufacturers) of eyeglass lenses.

[0032] An embodiment of the present invention aims to provide a technology related to eyeglass lenses that preemptively address phototoxicity to eye cells while appropriately managing the inventory of lens substrates or functional film materials.

[0033] Technical methods for solving technical problems

[0034] The first embodiment of the present invention is a supply system for eyeglass lenses, comprising:

[0035] The spectral transmittance setting unit sets the spectral transmittance of the eyeglass lens based on a relation selected from at least one of the following:

[0036] (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused.

[0037] (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered.

[0038] (3) The relationship between the wavelength of light and the irradiance that distinguishes whether the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells in the wearer of the eyeglass lens;

[0039] The task of determining the content of the task is shared by material A, which reduces the transmittance of a specified wavelength range S, and material B, which reduces the transmittance of another specified wavelength range T.

[0040] The second embodiment of the present invention is a spectacle lens supply system according to the first embodiment.

[0041] The spectral transmittance setting unit sets the spectral transmittance of the eyeglass lens based on the relationships 1 to 3.

[0042] Material A is a lens substrate, and material B is a dye.

[0043] The lens substrate satisfies ranges 1 and 2, and the dye satisfies range 3.

[0044] The third embodiment of the present invention is a spectacle lens supply system according to the first embodiment, wherein the spectral transmittance setting unit sets the spectral transmittance of the spectacle lens according to the attributes of the wearer of the spectacle lens.

[0045] The fourth embodiment of the present invention is a spectacle lens supply system according to the first or second embodiment, wherein the spectral transmittance setting unit sets the spectral transmittance of the spectacle lens based on the solar radiation intensity of the region where the spectacle lens is used and the spectral transmittance of the wearer's eye.

[0046] The fifth embodiment of the present invention is a spectacle lens supply system according to any one of the first to fourth embodiments, wherein the spectral transmittance setting unit sets the spectral transmittance of the spectacle lens based on the relationships 1 to 3.

[0047] The above embodiments can be combined in the following embodiments.

[0048] The sixth embodiment of the present invention is a method for supplying spectacle lenses, comprising:

[0049] The spectral transmittance setting process sets the spectral transmittance of the eyeglass lens based on a relation selected from at least one of the following relationships.

[0050] (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused.

[0051] (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered.

[0052] (3) The relationship between the wavelength of light and the irradiance that distinguishes whether the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells in the wearer of the eyeglass lens;

[0053] The task of determining the content of the task is shared by material A, which reduces the transmittance of a specified wavelength range S, and material B, which reduces the transmittance of other specified wavelength ranges T.

[0054] The seventh embodiment of the present invention is a design method for eyeglass lenses.

[0055] have:

[0056] The spectral transmittance setting process sets the spectral transmittance of the eyeglass lens based on a relation selected from at least one of the following relationships.

[0057] (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused.

[0058] (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered.

[0059] (3) The relationship between the wavelength of light and the irradiance that distinguishes whether the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells in the wearer of the eyeglass lens;

[0060] The task of determining the content of the task is shared by material A, which reduces the transmittance of a specified wavelength range S, and material B, which reduces the transmittance of other specified wavelength ranges T.

[0061] The eighth embodiment of the present invention is a method for manufacturing an eyeglass lens, comprising:

[0062] The spectral transmittance setting process sets the spectral transmittance of the eyeglass lens based on a relation selected from at least one of the following relationships.

[0063] (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused.

[0064] (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered.

[0065] (3) The relationship between the wavelength of light and the irradiance that distinguishes whether the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells in the wearer of the eyeglass lens;

[0066] The task of determining the content of the task is shared by material A, which reduces the transmittance of a specified wavelength range S, and material B, which reduces the transmittance of other specified wavelength ranges T.

[0067] In the manufacturing process, materials A and B are determined using the aforementioned content to manufacture eyeglass lenses with a transmittance set by the aforementioned spectral transmittance setting process.

[0068] The ninth embodiment of the present invention is a program for a supply system of eyeglass lenses, in which a computer functions as a spectral transmittance setting unit and a content determination unit. The spectral transmittance setting unit sets the spectral transmittance of the eyeglass lenses based on a relation selected from at least one of the following relations.

[0069] (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused.

[0070] (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered.

[0071] (3) The relationship between wavelength of light and irradiance that corresponds to the range of infiltration required for the eye cells of the wearer of the spectacle lens, and whether or not it changes the infiltration of the eye cells.

[0072] The task of achieving the selected relationship is shared by material A, which reduces the transmittance of a specified range S, and material B, which reduces the transmittance of other specified ranges T.

[0073] The effects of the invention

[0074] According to one embodiment of the present invention, it is possible to provide, while simultaneously supplying a stock of materials for lens substrates or functional films, technologies related to spectacle lenses that have been preemptively countered to phototoxicity to eye cells. Attached Figure Description

[0075] Figure 1 The irradiance at the location of the object illuminated by each light source (10nm half-width) used in the experiment (vertical axis: unit W / m²) 2 The graph shows the relationship between wavelength (horizontal axis: unit is nm) and lens epithelial cells, along with changes in their morphology and migration ability. Sunlight is also included as a reference in this graph.

[0076] Figure 2 From Figure 1 The graph derived from the boundary line represents the shielding characteristics of optical filters that suppress large and middle effects. It is a graph showing the relationship between transmittance (vertical axis: in %) and wavelength (horizontal axis: in nm).

[0077] Figure 3A This is a graph showing the relationship between transmittance (vertical axis: in %) and wavelength (horizontal axis: in nm) with FT11(λ) (left), FT21(λ) (middle), and FT31(λ) (right).

[0078] Figure 3B This is a graph showing the relationship between transmittance (vertical axis: in %) and wavelength (horizontal axis: in nm) with curves for FT11(λ), ​​FT21(λ), ​​FT31(λ), ​​FT32(λ), FT22´(λ), and FT21(λ).

[0079] Figure 4 In Example 1, the graph with the horizontal axis (unit: nm) as wavelength and the vertical axis as the "relative value of individual user data relative to the reference value" is a graph where, as individual data, the double-dotted line represents the relative illuminance of the user's environment relative to the reference solar illuminance, and the single-dotted line represents the relative transmittance of the intraocular lens transplant eye relative to the standard eye for wearer J.

[0080] Figure 5 In Example 1, the graph is plotted with spectral transmittance (in %) as the vertical axis and wavelength (in nm) as the horizontal axis. The dotted line represents the upper limit of spectral transmittance suitable for wearer J under the baseline condition (AM1.5), the dashed line represents the upper limit of spectral transmittance suitable for wearer J within the area where the eyeglass lens is used, and the solid line represents the spectral transmittance of the eyeglass lens.

[0081] Figure 6 In Example 1, the graph is plotted with spectral transmittance (in %) as the vertical axis and wavelength (in nm) as the horizontal axis. The dashed line represents the spectral transmittance of the lens substrate, the dotted line represents the spectral transmittance of the functional film, and the solid line represents the spectral transmittance of the eyeglass lens.

[0082] Figure 7 In Example 2, the graph with wavelength (unit: nm) on the horizontal axis and "relative value of individual user data relative to the reference value" on the vertical axis is a graph where, as individual data, the relative illuminance in the user's environment relative to the reference solar illuminance is represented by a double-dotted line, and the relative transmittance of the intraocular lens transplant eye relative to the standard eye for wearer K is represented by a single-dotted line.

[0083] Figure 8 In Example 2, the graph is plotted with spectral transmittance (in %) as the vertical axis and wavelength (in nm) as the horizontal axis. The dotted line represents the upper limit of spectral transmittance suitable for wearer K under the baseline condition (AM1.5), the dashed line represents the upper limit of spectral transmittance suitable for wearer K within the area where the eyeglass lens is used, and the solid line represents the spectral transmittance of the eyeglass lens.

[0084] Figure 9 In Example 2, the graph is plotted with spectral transmittance (in %) as the vertical axis and wavelength (in nm) as the horizontal axis. The dashed line represents the spectral transmittance of the lens substrate, the dotted line represents the spectral transmittance of the functional film, and the solid line represents the spectral transmittance of the eyeglass lens.

[0085] Figure 10 This is a schematic diagram of the constituent modules of a spectacle lens supply system according to one embodiment of the present invention.

[0086] Figure 11 This is a schematic flowchart of a spectacle lens supply system as one embodiment of the present invention. Detailed Implementation

[0087] Hereinafter, one embodiment of the present invention will be described. In this specification, "~" means above and below a specified value. All content not described below may be quoted from Non-Patent Document 1. When discussing the reception of light (where there is an object irradiated by light), the expression irradiance is used; otherwise, the expression radiant intensity is used.

[0088] In spectacle lenses, the "object-side surface" refers to the surface of the eyeglasses with the lens that is located on the object side when the wearer is wearing them, while the "eye-side surface" refers to the opposite, that is, the surface of the eyeglasses with the lens that is located on the eye side when the wearer is wearing them. This relationship also applies to the lens substrate that forms the basis of the spectacle lens. That is, the lens substrate also has an object-side surface and an eye-side surface.

[0089] In this specification, "spectral transmittance" refers to the spectral transmittance at or near the center of the eyeglass lens when light is incident perpendicularly from the object-side surface relative to that surface. It should be noted that when the thickness of the peripheral portion of the eyeglass lens is small, the spectral transmittance at this peripheral portion can be managed in the same manner as in the case of the lens center, as described later in one embodiment of the invention, to further suppress the risk of phototoxicity.

[0090] "Transmittance" varies depending on the position of the glasses and the angle of incidence towards the glasses, but for safety reasons, the value with the highest transmittance, when the light is incident perpendicularly to the eye point, is managed.

[0091] "Eye point" refers to the point through which the line of sight passes when looking towards a designated location (e.g., directly in front) while wearing eyeglasses with lenses. In the case of progressive refractive power lenses that provide refractive power from far to near, the eye point can be used at the designated far eye point for each lens. In the case of intermediate near lenses, the eye point can be the point through which the line of sight passes when looking towards an object located at an intermediate distance (1m to 40cm).

[0092] In cases where the transmittance is high when light passes through a location other than the eyepoint, or where the illuminance after transmission is high (e.g., when the sun is at a high position), the transmittance at that location can be managed.

[0093] Furthermore, the transmittance can be reduced in areas such as the lower part of the lens where sunlight is less likely to enter the eye. This can lead to effects such as making it easier to read from below and improving the appearance through a gradual transition.

[0094] One embodiment of the present invention provides an eyeglass lens that can be a single-focus lens or a progressive refractive power lens. In the case of a progressive refractive power lens, it can be an intermediate-near lens for objects at intermediate distances (1m to 40cm) or near distances (40cm to 10cm), a near-near lens for objects at such near distances, or a far-near lens for objects at far distances (e.g., 2m to infinity) and the aforementioned near distances.

[0095] <The principle of setting the spectral transmittance of eyeglass lenses>

[0096] One embodiment of the present invention provides a lens supply system for eyeglasses that may have the following configuration.

[0097] "A spectacle lens supply system includes a spectral transmittance setting unit, which sets the spectral transmittance of the spectacle lens based on a relation selected from at least one of the following: the solar radiation intensity of the region where the spectacle lens is used and the spectral transmittance of the eye of the wearer of the spectacle lens."

[0098] (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused.

[0099] (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered.

[0100] (3) The relationship between wavelength of light and irradiance that distinguishes whether or not the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells by the wearer of the eyeglass lens.

[0101] The relationship between the wavelength of light and irradiance can be used to distinguish whether changes in the morphology of the eye cells (lens epithelial cells in the following example) of the eyeglass lens wearer cause morphological changes. This relationship can be represented by a curve that differentiates between light wavelength and irradiance to determine whether changes in the morphology of eye cells occur. Figure 1 ( Figure 1 , Figure 2 (solid line).

[0102] The relationship between light wavelength and irradiance can be used to differentiate whether the migration ability of eye cells changes in the wearer of eyeglass lenses. A curve representing the relationship between light wavelength and irradiance can be used to distinguish whether the migration ability of eye cells changes (e.g., decreases). Figure 2 .

[0103] curve Figure 2 One of them (represented as "curve") Figure 2 ")for Figure 1 , Figure 2 The dotted line distinguishes between migration speed decreases exceeding 75% (left side of the line) and decreases less than 75% (right side of the line). Curve Figure 2 The other one (represented as "Graph 3") is Figure 1 , Figure 2 The single-dot dashed line is used to distinguish between migration speed decreases of more than 35% (left side of the line) and less than 35% (right side of the line).

[0104] The relationship between the wavelength of light and irradiance, which distinguishes whether it changes the infiltration of the eye cells of the wearer of the eyeglass lens, can be a graph 3 that distinguishes whether the infiltration of the eye cells changes (e.g., increases) in the relationship between the wavelength of light and irradiance. Considering that the possibility of secondary cataracts due to infiltration of lens epithelial cells is increased, similar to the relationships 1 and 2 above, in one aspect of the present invention, the change in infiltration is defined as relationship 3.

[0105] Relationships 1, 2, and 3 are not limited to being represented by curves; they can also be used for data acquisition.

[0106] "Solar irradiance in areas where eyeglass lenses are used" can be expressed as the annual average solar irradiance in those areas. In addition to the annual average solar irradiance, in Japan, the total daily solar radiation (monthly average, annual average, etc.) provided by the Japan Meteorological Agency can also be used. "Solar irradiance" refers to the amount of radiant energy received by a unit area from the sun per unit time (irradiance), and the unit is usually kilowatts per square meter (kW / m²). 2 ) or watts per square meter (W / m 2 In particular, solar radiation from all directions of the sky is called total solar radiation, and the total solar radiation energy received per unit area on a horizontal surface is called total solar radiation amount. Solar radiation refers to the radiation in the wavelength range of 0.29 to 3 μm, which accounts for approximately 97% of all energy in solar radiation originating from the high-temperature sun with a surface temperature of approximately 6000 K.

[0107] "Spectral transmittance of the wearer's eye for spectacle lenses" refers to the overall spectral transmittance of the eye, including the intraocular lens, when the wearer is using an intraocular lens. In this specification, "spectral transmittance" refers to the spectrum (or graph) with transmittance (%) on the vertical axis and wavelength (nm) on the horizontal axis. Spectral transmittance is also known as spectral transmittance.

[0108] It should be noted that when the wearer is not using an intraocular lens, the term refers to the spectral transmittance of the eye. The spectral transmittance of the eye can be measured for each individual wearer, or typical spectral transmittance values ​​corresponding to different eras, ethnicities, etc., can be prepared in advance and selected based on the wearer's characteristics. In the case of intraocular lens wearers, estimated values ​​based on catalog values ​​of intraocular lenses can be used.

[0109] The following example illustrates how the spectral transmittance of a spectacle lens is set based on the solar radiation intensity of the region where the lens is used and the spectral transmittance of the wearer's eye, according to a relation selected from at least one of relations 1, 2, and 3 above. For ease of explanation, in the following examples, secondary cataracts are assumed to be a factor hindering health, and the eye cells are assumed to be lens epithelial cells.

[0110] The database is used in relation to the following relationship disclosed in Non-Patent Document 1.

[0111] • The relationship between the threshold of radiation that causes morphological changes in lens epithelial cells and wavelength 1 (ACTI1(λ))

[0112] • The relationship between the threshold of radiation that alters the migration ability of lens epithelial cells and wavelength 2 (ACTI2(λ), ACTI3(λ)).

[0113] ACTI2 refers to a slight reduction in migration ability (a reduction rate of 30% or more but less than 70%), while ACTI3 refers to a significant reduction in migration ability (a reduction rate of 70% or more).

[0114] It should be noted that a database relating the threshold of radiation intensity that alters the infiltration of lens epithelial cells to wavelength can be used, but this is omitted from the following text.

[0115] It should be noted that morphological changes in lens epithelial cells can be a significant cause of secondary cataracts. Therefore, regarding relation 1, preferably, a relation (curve) that does not lead to morphological changes in lens epithelial cells should be selected. Figure 1 (on the right side).

[0116] As the spectral transmittance required for the spectacle lens to not exceed each threshold, the required spectral transmittance FTx, when using solar irradiance ATOM, is as follows. In the following formula, x corresponds to numbers 1 to 3 in ACTI1 to 3.

[0117] FTx(λ)×ATOM(λ)×P(λ)≤ACTIx(λ)・・・(Formula 1)

[0118] P(λ) is a coefficient representing the degree to which the intensity (irradiance) of light incident on the eye decreases, based on physiological characteristics. P(λ) can also be related to the area of ​​the pupil diameter (unit: mm). 2 The coefficients corresponding to this are given. In this case, the pupil size also changes depending on the wavelength of the incident light, so the wavelength λ is set as a variable.

[0119] P(λ) can also use other known data. Considering the different physiological characteristics of each person, a certain characteristic benchmark is specified, and the coefficient and benchmark P(λ) under this condition are determined based on the measurement data of the human body. Furthermore, the characteristic measurement of each person is a relative value relative to the benchmark, and each person's P(λ) can be determined by multiplying the relative value with the benchmark P(λ).

[0120] It should be noted that P(λ) can also be a function related to the pupil diameter and the spectral transmittance of the iris. This function may also be referred to as the "pupil diameter function" in this specification. It should be noted that P(λ) can be a number between 0 and 1. The pupil diameter typically varies due to important reasons described at the following URL (https: / / acuvuevision.jp / eyelife / vol18), and also due to the spectral shape.

[0121] ATOM(λ) represents the spectral irradiance of the environment, specifically the irradiance at various wavelengths. ACTI(λ) here represents the transmission spectrum of the cell when its properties change due to phototoxicity, equivalent to... Figure 1 , Figure 2 Solid lines, dotted lines, and dashed lines.

[0122] When the equality in Equation 1 above holds, FTx(λ) reaches its maximum value. The maximum spectral transmittance results in a brighter external view for the wearer of the eyeglass lens, which is therefore preferred. On the other hand, the inequality in Equation 1 above should also be allowed. It is meaningful to ensure sufficient margins for other filters, considering factors that significantly affect phototoxicity to the wearer's eyes, such as spectral irradiance and exposure time.

[0123] Therefore, Equation 1 above can also be adjusted by the coefficient B(λ) to form Equation 2 below.

[0124] FTx(λ)×ATOM(λ)×P(λ)=ACTIx(λ)×B(λ)・・・(Formula 2)

[0125] B(λ) is used when adjustments are needed based on the aforementioned important reasons and / or necessary conditions. As a specific value, it can be determined between 0 and 1, depending on the degree of the aforementioned important reasons and / or necessary conditions. B can be a value based on wavelength or a simple constant. For example, in individuals with a tendency to ptosis, light is blocked above the narrowest point of the pupil diameter, thus the risk is low, and they tend to be difficult to see; therefore, it is multiplied by 0.7 to match the degree of ptosis.

[0126] Furthermore, if ACTI1 to 3 mentioned above do not exist in the database, one aspect of the present invention can also be implemented. For example, if the upper limit of spectral transmittance FTx(λ)' exists in the database, the reference irradiance ATOM'(λ) and the reference pupil diameter P'(λ) can be used instead of ATOM(λ). The reference irradiance ATOM'(λ) refers to the ratio of the area where the eyeglass lens is used to the reference solar irradiance of, for example, an AM1.5 area (e.g., Tokyo). The reference pupil diameter P'(λ) refers to the ratio of the area where the eyeglass lens is used to the reference pupil diameter P0(λ) of, for example, an AM1.5 area (e.g., Tokyo). In this case, the following formula can be used.

[0127] FTx(λ)≤{FTx(λ)´×ATOM(λ)´×P(λ)´}÷{ATOM(λ)×P(λ)}・・・(Formula 3)

[0128] Equation 3 is modified as follows.

[0129] FTx(λ)≤[FTx(λ)´÷{ATOM(λ) / ATOM(λ)´}]÷{P(λ) / P(λ)´}・・・ (Formula 4)

[0130] The first square bracket on the right side of Equation 4 is equivalent to ACTIx ÷ ATOM.

[0131] Preparing for the disclosure of non-patent document 1

[0132] • Through continuous light irradiation experiments of 24 to 30 hours, ACTI1 showed relatively severe phototoxicity (here, "phototoxicity" refers to a condition where more than 20% of all cells undergo abnormal changes in cell morphology).

[0133] • Changes in cell migration ability were observed (a significant decrease in migration speed), but the extent was approximately 30-70% of the decrease in ACTI2.

[0134] • ATCTI3, which exhibits strong phototoxicity relative to its migration ability, reduces its migration rate to below 30%.

[0135] The database.

[0136] Using this database and by employing either Equation 1 or Equation 2 above, ACTI1 (the aforementioned curve) is obtained. Figure 1 ), ACTI2 (the above curve) Figure 2 ), ACTI3 (as shown in Figure 3 above), through which the spectral transmission characteristics of the spectacle lens relative to the ambient light (ATOM1(λ)) of the region where the spectacle lens is used are obtained. These are referred to as FT11(λ), ​​FT21(λ), ​​and FT31(λ).

[0137] Regarding ATOM1(λ), ​​to compare irradiance, the irradiance of each wavelength of AM1.5 sunlight incident on the eye and reaching the lens is converted to a half-width of 10 nm to become a point value. ACTx(λ) is the value when using light with a half-width of approximately 10 nm relative to its respective center wavelength.

[0138] To take into account the characteristics of ambient light in the area where the eyeglass lens is used, the following implementation method can be adopted. As a transmission characteristic of the eyeglass lens provided by one embodiment of the present invention, firstly, the characteristic with the lowest transmittance (also called the filtering characteristic) can be calculated by assuming the ambient light with the highest intensity. Then, if there is an intensity of ambient light, the desired filtering characteristic is obtained by multiplying it by the ratio r(λ) = ATOM1(λ) / ATOMy(λ) of the spectral irradiance 1 (ATOM1) of the reference environment to the spectral irradiance y (ATOMy) of the living environment in the area where the eyeglass lens is used. This ratio r(λ), when considering the irradiation time, becomes the aforementioned adjustment coefficient B1(λ).

[0139] FT31(λ) represents the filtering property with the lowest transmittance among FT11(λ), ​​FT21(λ), ​​and FT31(λ). Light passing through a spectacle lens with FT31(λ) filtering properties will not alter the migration ability of lens epithelial cells, making it the safest for the cells of the eye.

[0140] On the other hand, as a basic function of the eye, it becomes difficult to see objects and to recognize their colors. Seeing objects is called "object recognition," and recognizing their colors is called "color discrimination."

[0141] Furthermore, when the ambient light intensity is low, excessive filtering of light makes object recognition and color discrimination even more difficult.

[0142] In contrast, we also consider multiplying FT31(λ) by the aforementioned r(λ) to reduce the filtering characteristics by taking into account the ambient light level. In this case, recognition and color discrimination become easier. However, if the ambient light is not suppressed to the assumed level, the safety for the cells decreases.

[0143] Therefore, the ambient light irradiance and exposure time to light can also be considered to determine the final filtering characteristics. It should be noted that it is not necessary to make the transmittance lower than FT31(λ), ​​and from the point of view of recognition, it is not desirable to reduce the transmittance. Therefore, FT31(λ) can also be used as the lower limit of transmittance.

[0144] FT21(λ) among FT11(λ), ​​FT21(λ), ​​and FT31(λ) is a filtering property designed to prevent abnormalities caused by impaired migration ability of lens epithelial cells.

[0145] With a lower transmittance than FT21(λ) in terms of filtering properties, the reduction in migration velocity, an indicator of changes in migration ability, was suppressed to below 30%. Furthermore, even under light weaker than sunlight, the reduction was suppressed to below the same rate. In reality, many people do not spend a significant amount of time in direct sunlight; therefore, the impact on migration ability is considered minimal. Considering the cells of the lens, from the perspective of recognition and color discrimination, this is a practically useful characteristic for many people.

[0146] FT11(λ), ​​one of the three filter properties (FT11(λ), ​​FT21(λ), ​​and FT31(λ), ​​is a filtering property used to prevent morphological abnormalities of lens epithelial cells. Among the three filtering properties, FT11(λ) has the highest transmittance. Therefore, when using FT11(λ), ​​object recognition and color discrimination, fundamental functions of the eye, become easier. On the other hand, exposure to high-intensity ambient light may have adverse effects on eye cells. However, during periods of reduced ambient light, such as when using eyeglass lenses, even the filtering properties of FT11(λ) may have their impact on migration ability suppressed within a limited range.

[0147] In contrast, multiplying FT11(λ) by the aforementioned r(λ) is also considered to enhance the filtering properties by taking into account the level of light environment. In this case, the safety for cells is improved. However, under low light environment conditions, recognition and color discrimination become difficult.

[0148] Therefore, the final filtering characteristics can be determined by considering the ambient light irradiance of the eye and the duration of exposure to light. It should be noted that if there are no problems with object recognition and color discrimination, it is not necessary to make the transmittance higher than FT11(λ). Furthermore, from the perspective of the effect on cells, it is not desirable to increase the transmittance. Therefore, FT11(λ) can be the upper limit of the transmittance.

[0149] Figure 3A The graphs show the relationship between transmittance (vertical axis: in %) and wavelength (horizontal axis: in nm), specifically FT11(λ) (left side, legend 〇), FT21(λ) (middle side, legend △), and FT31(λ) (right side, legend ◇).

[0150] As a practically effective range of transmittance for filters, the values ​​between FT31(λ) and FT11(λ) can be considered, with FT21(λ) as the reference and set as the boundary.

[0151] More specifically, the boundary on the side with lower transmittance sets the transmittance of FT31(λ) to twice that of FT32(λ). In the life of a wearer of eyeglass lenses, under sunlight, the amount of irradiance is reduced due to pupil constriction; therefore, it is considered that assuming the average irradiance is halved would affect the migration ability.

[0152] Furthermore, the boundary of the side with high transmittance is compared with each wavelength using FT11(λ) and FT22(λ), which sets the transmittance of FT21(λ) to twice that of FT22(λ), and the side with low transmittance is set as FT22´(λ).

[0153] Figure 3B This is a graph showing the relationship between transmittance (vertical axis: in %) and wavelength (horizontal axis: in nm) with curves for FT11(λ), ​​FT21(λ), ​​FT31(λ), ​​FT32(λ), FT22´(λ), and FT21(λ).

[0154] Considering the achieved effect (suppression of phototoxicity expression) and the manufacturing cost of the filter, providing a filter with... Figure 3B In this context, the filter properties of the eyeglass lens with transmittance between FT22´(λ) and FT32(λ) are realistic and therefore preferred.

[0155] Furthermore, since cells exposed to direct sunlight become unable to migrate within the pupil, the idea of ​​averaging the irradiation in FT11(λ) is not applicable in one embodiment of the present invention.

[0156] As conditions for filtering characteristics that minimize the impact on cells while ensuring a good field of vision for the wearer of the eyeglass lenses, firstly, the range of transmittance of practically effective filters that meets the above-mentioned requirements is listed. In addition, the following conditions are listed.

[0157] That is, the range of the spectroradiant irradiance IRRA(λ) on the lens surface is set to a minimum between the wavelength integrals of visible light for IRRA1(λ) and -IRRA2(λ), and the wavelength integral of the spectroradiant irradiance IRRA(λ) with the standard spectroscopic visual efficiency V(λ) (photopic vision) is set to a maximum. For more information, please refer to JIS Z 8785:2019 "ISO 23539:2005 (CIES 010:2004) Photometry – CIE Physical Photometric Systems".

[0158] It should be noted that the following formula is obtained by considering AM1.5 sunlight as the reference.

[0159] IRRA1(λ)=ATOM1×FT(λ)22´・・・(Formula 5)

[0160] IRRA2(λ)=ATOM1×FT(λ)32・・・(Formula 6)

[0161] The integral value of IRRA(λ)×V(λ) is maximized in the visible light region (390nm~720nm), and the range of IRRA(λ) with the smallest integral value of IRRA(λ) is suitable for use in eyeglass lenses.

[0162] <The specific structure of the eyeglass lens used to implement this principle>

[0163] For those with in Figure 3A , Figure 3B The specific means of achieving the spectacle lens with the spectral transmittance illustrated in the example are not limited.

[0164] For example, light filtering properties can be achieved by mixing a colorant into the lens substrate, which is the main component of an eyeglass lens. Multiple types of colorants can also be mixed into the lens substrate. Examples of multiple types of colorants include material A, which reduces the transmittance over a specified wavelength range S, and material B, which reduces the transmittance over another specified wavelength range T.

[0165] There are no limitations on the composition of the lens substrate; it can be resin or glass. The resin can be a thermosetting resin, a photosetting resin, or other resins.

[0166] Furthermore, the spectral transmittance of the eyeglass lens can be achieved using functional films disposed on the main surfaces of the lens substrate, both on the object side and the eyeball side. These functional films may include a primer film disposed directly above the lens substrate, and a hard coating film, anti-reflective film, anti-fouling film, etc., disposed thereon. The term "functional film" can also be described as material A, which reduces the transmittance over a specified wavelength range S, and material B, which reduces the transmittance over another specified wavelength range T.

[0167] Furthermore, a light-switching material can be used in at least one of the lens substrate and the functional film. By utilizing the function of the light-switching material, the amount of sunlight incident on the wearer's eye through the eyeglass lens can be set to approximately a constant, regardless of variations in the intensity of solar radiation (sunlight).

[0168] In one embodiment of the present invention, the task of achieving the spectral transmittance of the eyeglass lens can be shared by the lens substrate and the functional film. In this case, the lens substrate corresponds to material A described above, and the functional film corresponds to material B described above. This configuration is preferred due to the following points, which will be described in detail below.

[0169] The range of morphological changes and migration capabilities of the lens epithelial cells are defined. Based on this, the required spectral transmittance of the spectacle lens is set in relation to at least one of the following: the region of use of the spectacle lens, the environment of use of the spectacle lens, and the condition of the wearer's eye (e.g., the presence or absence of an intraocular lens, and its color if a lens is present). (Preferably, the condition of the eye and the region of use of the spectacle lens and / or the environment of use of the spectacle lens). It should be noted that the region of use and the environment of use of the spectacle lens are also described later (specific examples and preferred examples of the spectacle lens supply system).

[0170] To determine the required spectral transmittance for eyeglass lenses, it is preferable to construct a structure that allows for easy customization of the required spectral transmittance. The spectral transmittance can be easily customized using a lens substrate or a functional film.

[0171] For example, while making the functional film of the eyeglass lenses provided to various wearers universal, the spectral transmittance of the eyeglass lenses required by each wearer can be customized using the lens substrate. The lens substrate can be dyed (usually dyed) by immersing it in dye. Thus, if various lens substrates can be prepared, the film formation process of the functional film can be carried out simultaneously with each of these lens substrates, resulting in good work efficiency.

[0172] Conversely, while standardizing the lens substrate for eyeglass lenses supplied to various wearers, the spectral transmittance of eyeglass lenses required by each wearer can be customized using functional films. More specifically, in the case of a hard coating film, a specified dye can be mixed into the raw material solution of the hard coating film and combined with the lens substrate to achieve the spectral transmittance of the eyeglass lens. Alternatively, the lens pair with the hard coating film attached can be immersed in dye to perform a dyeing process on the hard coating of the lens with the hard coating film (dyeable hard coating).

[0173] When the functional film is an anti-reflective film, the composition of the raw materials for the anti-reflective film and its multilayer structure (a stacked structure of low-reflection film and high-reflection film) can be combined with the lens substrate to achieve the spectral transmittance of the eyeglass lens.

[0174] Furthermore, functional films, besides those with static transmission characteristics such as anti-reflective films and bandpass films, can also include films with dynamic transmission characteristics, such as dimming films and electronic dimming films. By offering both types in a series, the former can be recommended to users who wear glasses during the day and outdoors, while the latter can be recommended to users who use them both at night and indoors. When choosing from multiple dimming films, factors such as transmittance, color rendering index, and response time can be considered.

[0175] Generally, the formation of functional films is efficient because it allows for simultaneous formation on many lens substrates. However, in one embodiment of the present invention, each lens substrate (or at least a portion of the lens substrates with functional films) is dyed using a dye specified according to the desired spectral transmittance for each wearer's eyeglass lenses. This is a different process from current functional film formation methods.

[0176] Customizing the spectral transmittance using the above-mentioned dyeing method has the following advantages.

[0177] First, when defining the range of morphological changes and migration capabilities of lens epithelial cells, such as... Figure 1 as well as Figure 2 As shown, it is preferred to achieve a minimum level of light filtering properties (FT31(λ)) that does not cause morphological changes in the lens epithelial cells. Therefore, light of a wavelength that should be blocked, as commonly defined by the eyeglass lens provided by one embodiment of the present invention, is blocked using a hard coating film, an anti-reflective film, or the like.

[0178] Based on this, corresponding to the filtering characteristics (between FT31(λ) and FT11(λ)) that reduce the migration ability of lens epithelial cells, each lens substrate (or at least a portion of the lens substrates with functional films) is stained to satisfy the filtering characteristics while ensuring sufficiently high spectral transmittance.

[0179] For example, each lens substrate (or at least a portion of a lens substrate with a functional film formed thereon) can be endowed with the ability to realize Figure 3A The FT21(λ) transmission spectrum exhibits sufficiently high spectral transmittance at one of the wavelengths (e.g., a maximum value near 440 nm). Conversely, staining can be performed to achieve an absorption spectrum that avoids at least one of these wavelengths.

[0180] As another sample, while satisfying the filtering characteristics of the lens substrate to achieve the range of morphological changes and migration ability of lens epithelial cells (range 1, 2), the filtering characteristics of the functional membrane or the lens substrate and / or the functional membrane can be satisfied to achieve the range of infiltration of lens epithelial cells (range 3).

[0181] For example, morphological changes only occur under high-intensity light. Similarly, large changes in migration ability also only occur under high-intensity light. On the other hand, changes in wettability and small changes in migration ability occur under non-high-intensity light. In view of this, while large changes in morphological changes and migration ability can be achieved through the formation of functional films to avoid the necessary minimum risks, small changes in wettability and migration ability can be achieved through small-batch, highly flexible dyeing processes.

[0182] If the above dyeing method is used, it is also possible to insert a dyeing process into each lens substrate (or at least a portion of lens substrates with functional films) during the gaps in the mass production of many eyeglass lenses. As a result, it is possible to customize the spectral transmittance at low cost and also improve work efficiency.

[0183] Alternatively, a light-adjusting material can be used instead of dyeing. For example, it can be set to have at least one absorption spectrum that avoids the wavelength at which the transmission spectrum reaches its maximum.

[0184] At the wavelength where the spectral transmittance of the spectacle lens reaches its maximum, the spectral transmittance of the dyed material and functional film reaches its minimum, or the shape of the spectral transmittance curve bulges downward. Thus, under the condition that the shielding effect caused by the suitable dyed material and functional film is fully utilized, the shielding effect at the aforementioned wavelength is further enhanced, while the maximum value is eliminated.

[0185] For example, when the dyeing material of the lens substrate meets the aforementioned conditions, the blocking effect is enhanced at the upper and lower parts of the lens where the lens thickness increases, corresponding to the increased light transmission length, especially at the aforementioned wavelengths. In this way, the risks of sunlight from above and reflections from the ground can be effectively prevented, while maintaining a maximum value at the center of the lens to ensure brightness and chroma.

[0186] Furthermore, since the downward-protruding wavelength bands and upward-protruding wavelength bands of the element are different from each other, it is advantageous that a configuration with arbitrary spectral transmittance distribution can be easily formed. In particular, it can reduce the risk of lenses that unexpectedly give the wearer transmittance exceeding the threshold due to errors in adjusting transmittance during manufacturing.

[0187]

[0188] This concludes the description of the principle for setting the spectral transmittance of eyeglass lenses and the specific means for achieving this principle. A specific example of these principles is given below. This invention is not limited to this specific example.

[0189] First, prepare a database of ACTI1 to 3 as described above. Assume the wearer is ACTI2. In the following examples, Equations 3 and 4 will be used.

[0190] As an example 1, the environment in which wearer J uses glasses lenses is assumed to be an environment where the radiation intensity is 20% stronger than the reference solar radiation intensity.

[0191] As in Example 2, the environment is the same as in Example 1, but it is assumed that the wearer K has already had a yellow transparent intraocular lens implanted.

[0192] Figure 4 In Example 1, the graph with the horizontal axis (unit: nm) as wavelength and the vertical axis as the "relative value of individual user data relative to the reference value" is a graph where, as individual data, the double-dotted line represents the relative illuminance of the user's environment relative to the reference solar illuminance, and the single-dotted line represents the relative transmittance of the intraocular lens transplant eye relative to the standard eye for wearer J.

[0193] Figure 5 In Example 1, the graph is plotted with spectral transmittance (in %) as the vertical axis and wavelength (in nm) as the horizontal axis. The dotted line represents the upper limit of spectral transmittance suitable for wearer J under the baseline condition (AM1.5), the dashed line represents the upper limit of spectral transmittance suitable for wearer J within the area where the eyeglass lens is used, and the solid line represents the spectral transmittance of the eyeglass lens.

[0194] Figure 6 In Example 1, the graph is plotted with spectral transmittance (in %) as the vertical axis and wavelength (in nm) as the horizontal axis. The dashed line represents the spectral transmittance of the lens substrate, the dotted line represents the spectral transmittance of the functional film, and the solid line represents the spectral transmittance of the eyeglass lens.

[0195] Figure 7 In Example 2, the graph with wavelength (unit: nm) on the horizontal axis and "relative value of individual user data relative to the reference value" on the vertical axis is a graph where, as individual data, the relative illuminance in the user's environment relative to the reference solar illuminance is represented by a double-dotted line, and the relative transmittance of the intraocular lens transplant eye relative to the standard eye for wearer K is represented by a single-dotted line.

[0196] Figure 8 In Example 2, the graph is plotted with spectral transmittance (in %) as the vertical axis and wavelength (in nm) as the horizontal axis. The dotted line represents the upper limit of spectral transmittance suitable for wearer K under the baseline condition (AM1.5), the dashed line represents the upper limit of spectral transmittance suitable for wearer K within the area where the eyeglass lens is used, and the solid line represents the spectral transmittance of the eyeglass lens.

[0197] Figure 9 In Example 2, the graph is plotted with spectral transmittance (in %) as the vertical axis and wavelength (in nm) as the horizontal axis. The dashed line represents the spectral transmittance of the lens substrate, the dotted line represents the spectral transmittance of the functional film, and the solid line represents the spectral transmittance of the eyeglass lens.

[0198] In this specific example, the lens substrate contains a colorant, and the functional film is also dyed.

[0199] The above details the process of obtaining eyeglass lenses or eyeglasses from the database based on relations 1 and 2. The system implementing the above description is as follows.

[0200] <Eyeglass Lens Supply System>

[0201] Figure 10 This is a schematic diagram of the constituent modules of a spectacle lens supply system as one embodiment of the present invention.

[0202] Figure 11 This is a schematic flowchart of a spectacle lens supply system as one embodiment of the present invention.

[0203] One aspect of the present invention provides a lens supply system for eyeglasses with the following configuration.

[0204] "A lens supply system for eyeglasses, comprising:"

[0205] The spectral transmittance setting unit sets the spectral transmittance of the eyeglass lens based on a relation selected from at least one of the following relations.

[0206] (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused.

[0207] (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered.

[0208] (3) The relationship between the wavelength of light and the irradiance that distinguishes whether the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells in the wearer of the eyeglass lens;

[0209] The task of determining the content of the task is shared by material A, which reduces the transmittance of a specified wavelength range S, and material B, which reduces the transmittance of another specified wavelength range T.

[0210] According to one embodiment of the present invention, a spectacle lens can be supplied with appropriate inventory of lens substrate materials or functional film materials, while taking measures against phototoxicity to eye cells in advance. With this configuration, the problems of the present invention can be solved even without considering the solar radiation intensity of the area where the spectacle lens is used or the spectral transmittance of the wearer's eye.

[0211] (Regarding databases with relational properties 1 and 2)

[0212] In one embodiment of the present invention, the database includes the relationship between morphological changes and migration abilities of eye cells described in Non-Patent Document 1 and the wavelength of light (i.e., relationships 1 and 2, for example: Figure 1 (Transmission spectroscopy) and Figure 2 (Spectroscopic transmittance), also known as big data. Of course, we can also prepare big data with relational type 3.

[0213] (Specific examples and preferred examples of eyeglass lens supply systems)

[0214] Hereinafter, specific examples and preferred examples of a spectacle lens supply system according to one embodiment of the present invention will be described. As an example, the spectacle lens supply system according to one embodiment of the present invention has the following configuration.

[0215] The computer system of an optical shop can also have the following configuration.

[0216] • Input Section

[0217] Display Department

[0218] The control computer on the control side can also have the following configuration.

[0219] • The database recording section is related to the relationship between changes in the morphology, migration ability, and infiltrative properties of eye cells and the wavelength of light.

[0220] • Spectroscopic transmittance setting unit

[0221] • The content determination unit and the control computer unit share the task of determining the relationship between material A, which reduces the transmittance of a specified wavelength range S, and material B, which reduces the transmittance of other specified wavelength ranges T.

[0222] The controlling party can also act as the manufacturer of eyeglass lenses. Examples will be given later.

[0223] The input section has the function of inputting the characteristics of the purchaser of the eyeglasses (the future wearer of the eyeglass lenses). These characteristics include the prescribed usage area of ​​the eyeglass lenses (generally the purchaser's residence). In addition, it lists the season of use, intended use (use in snowy mountains, use during summer mountain climbing, use on the street, etc.). It also lists the usage time (the duration of outdoor use after sunrise, before sunset, and the time of daytime outdoor work). In this specification, the expression "usage environment (also known as living environment)" is used as a description including at least one of the prescribed usage area, season of use, intended use, and usage time of the eyeglass lenses. That is, this characteristic may include both the usage area and the usage environment of the eyeglass lenses. Furthermore, if color perception is important due to the presence or absence of color vision abnormalities, occupation, hobbies, preferences, etc., such information may also be included in this characteristic.

[0224] Furthermore, as information related to this characteristic based on specific cases, the following is listed: Patients who have undergone ophthalmic surgery have an increased risk of phototoxicity. Therefore, the approaching surgery date can also be input as information. Furthermore, the proximity of the surgery date to the date from which the spectral transmittance is set according to an embodiment of the present invention can ensure a safety margin regarding transmittance.

[0225] It should be noted that the intended use can also be automatically determined by corresponding to the lens's product number. For example, in the case of a mid-to-near lens, it is assumed that it will be used less outdoors during the day.

[0226] The "characteristic" may include at least one of the various pieces of information listed in this paragraph, and the various pieces of information may be combined appropriately according to the situation. Preferably, the characteristic includes at least the usage environment.

[0227] In summary, preferably, the aforementioned spectral transmittance setting unit sets the spectral transmittance of the eyeglass lens not only based on the solar radiation intensity of the region where the eyeglass lens is used and the spectral transmittance of the eye of the eyeglass lens wearer, but also based on the characteristics of the eyeglass lens wearer.

[0228] Input using the input section ( Figure 11 The content of S1 is sent to the control computer of the controller. At the controller, based on this content, while referring to the database recording unit (S2), the spectral transmittance is set using the spectral transmittance setting unit (S3). Here, the term "set" is used for good reason.

[0229] Based on the information input using the input unit, and while referring to the database record unit, the most suitable spectral transmittance for the buyer is determined, which is also included in the "Settings" section of this manual. However, in this case, the color of the eyeglass lens with this determined spectral transmittance is naturally one. Thus, when the eyeglass lens manufactured (dyed) by the factory is delivered to an optical shop, the buyer may be dissatisfied with the color of the eyeglass lens when they see it at the optical shop.

[0230] Therefore, in the spectral transmittance setting unit of the control computer, it is preferable to set multiple spectral transmittances of different colors of eyeglass lenses as selection options within the range 1 of morphological changes in eye cells and the range 2 of migration ability changes required by the buyer. For the sake of including this situation, it is referred to as "setting" of spectral transmittance in this specification. In the embodiment described in this paragraph, in an optical shop, multiple eyeglass lenses of different colors are displayed on a display unit (S4). The buyer selects one of these eyeglass lenses (S5). The input of this selection result and its transmission to the manufacturer via network X can be performed through the aforementioned input unit.

[0231] Based on the structure described in the above paragraph, it is possible to prevent buyers from being dissatisfied with the color of eyeglass lenses when they see them in an optician's store, thereby increasing customer satisfaction.

[0232] In addition to this configuration, the preferred spectacle lens supply system includes the aforementioned input section. This spectacle lens supply system does not require a spectral transmittance setting section; the color data of the spectacle lens corresponding to each of the multiple spectral transmittances set by the spectral transmittance setting section is provided by the spectacle lens supply system itself.

[0233] The selected relational task can be accomplished by using the content determination unit of the control computer to divide the task of material A (e.g., lens substrate) that reduces the transmittance of a specified wavelength range S and material B (e.g., other than the lens substrate, i.e., functional film) that reduces the transmittance of other specified wavelength ranges T (S6).

[0234] As described in the preceding paragraph, while effectively utilizing the function of the content determination unit, even when multiple spectral transmittance settings are configured in the spectral transmittance setting unit of the control computer, it is preferable to display eyeglass lenses of different colors corresponding to each spectral transmittance on the display unit of the optical shop computer (S4). Furthermore, it is preferable that the purchaser pre-selects a preferred color of eyeglass lens and inputs their selection using the aforementioned input unit of the optical shop computer (S5).

[0235] It should be noted that the display unit can show simulated images such as the visual effect of the appearance as seen from a third party and the field of vision through the lens as seen from the wearer. It can also have a drawing function for displaying the visual effect of the appearance from any angle and an angle-changing interface. It can also display changes in color vision taken into account when wearing the intraocular lens and the wearer's color vision abnormalities. By adopting this configuration, a third party other than the person with color vision abnormalities (e.g., a person with normal color vision who acts as an assistant to the person with color vision abnormalities) can, when purchasing the spectacle lenses according to one embodiment of the present invention, grasp changes in color vision and play an assistive role.

[0236] A tablet terminal that integrates the input unit and the display unit (described later) can also be used as a computer for an eyeglasses shop.

[0237] The database recording unit may or may not be included in the mold management system. For example, the database recording unit may be equipped in the control computer, the factory computer, or a server on a network.

[0238] The control computer unit functions as a computer device that performs information processing as instructed by a prescribed program. Specifically, it is composed of a combination of a CPU (Central Processing Unit), HDD (Hard Disk Drive), ROM (Read Only Memory), RAM (Random Access Memory), and external interface (I / F).

[0239] Based on the content selected and assigned by the buyer, spectacle lenses are manufactured (S7). The specific operations for manufacturing the spectacle lenses can employ known procedures. As a method for realizing the aforementioned selection, as described above in <The Principle for Setting the Spectacle Lens's Spectral Transmittance> and <The Specific Structure of the Spectacle Lens for Realizing the Principle>, the lens substrate material can contain a colorant, and the lens substrate and / or functional film can be dyed. The spectacle lenses manufactured in this way are then transported to an optical shop and delivered to the buyer there (S8).

[0240] <Design methods, manufacturing methods, and procedures for spectacle lens supply systems>

[0241] The technical concept of the spectacle lens supply system according to one embodiment of the present invention can be applied to spectacle lens design methods, spectacle lens manufacturing methods, and spectacle lens supply system procedures. The specific configurations of each invention are described below.

[0242] A method for designing eyeglass lenses, comprising:

[0243] The spectral transmittance setting process sets the spectral transmittance of the eyeglass lens based on a relation selected from at least one of the following relationships.

[0244] (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused.

[0245] (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered.

[0246] (3) The relationship between the wavelength of light and the irradiance that distinguishes whether the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells in the wearer of the eyeglass lens;

[0247] The task of sharing the workload is determined by material A, which reduces the transmittance of a specified wavelength range S, and material B, which reduces the transmittance of other specified wavelength ranges T.

[0248] A method for manufacturing eyeglass lenses, comprising:

[0249] The spectral transmittance setting process sets the spectral transmittance of the eyeglass lens based on a relation selected from at least one of the following relationships.

[0250] (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused.

[0251] (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered.

[0252] (3) The relationship between the wavelength of light and the irradiance that distinguishes whether the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells in the wearer of the eyeglass lens;

[0253] The task of sharing the responsibilities is determined by dividing the work into two parts: material A, which reduces the transmittance of a specified wavelength range S, and material B, which reduces the transmittance of other specified wavelength ranges T.

[0254] In the manufacturing process, materials A and B are determined using the aforementioned content to manufacture eyeglass lenses, giving them a transmittance set by the aforementioned spectral transmittance setting process.

[0255] "A program for a supply system of eyeglass lenses enables a computer to function as a spectral transmittance setting unit and a content determination unit. The spectral transmittance setting unit sets the spectral transmittance of the eyeglass lenses based on a relation selected from at least one of the following relations."

[0256] (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused.

[0257] (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered.

[0258] (3) The relationship between the wavelength of light and the irradiance that distinguishes whether the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells in the wearer of the eyeglass lens;

[0259] The task of achieving the selected relational relationship is shared by material A, which reduces the transmittance of a specified range S, and material B, which reduces the transmittance of other specified ranges T.

[0260] <Other>

[0261] The technical scope of the present invention is not limited to the above-described embodiments. It also includes forms with various modifications and improvements, within the scope within which the specific effects obtained by utilizing the constituent elements of the invention and their combinations can be deduced.

[0262] The aforementioned eye cells can be lens epithelial cells, retinal pigment epithelial cells, corneal endothelial cells, corneal epithelial stem cells, or subconjunctival fibroblasts. Among these, lens epithelial cells have a high phototoxicity sensitivity, resulting in a particularly pronounced effect of the present invention.

Claims

1. A supply system for eyeglass lenses, characterized in that, have: The spectral transmittance setting unit sets the spectral transmittance of the eyeglass lens based on a relation selected from at least one of the following: (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused. (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered. (3) The relationship between the wavelength of light and the irradiance that distinguishes whether the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells in the wearer of the eyeglass lens; The task of determining the content of the task is shared by material A, which reduces the transmittance of a specified wavelength range S, and material B, which reduces the transmittance of another specified wavelength range T.

2. The eyeglass lens supply system according to claim 1, characterized in that, The spectral transmittance setting unit sets the spectral transmittance of the eyeglass lens based on the relationships 1 to 3. Material A is a lens substrate, and material B is a dye. The lens substrate satisfies ranges 1 and 2, and the dye satisfies range 3.

3. The spectacle lens supply system according to claim 1, characterized in that, The spectral transmittance setting unit sets the spectral transmittance of the eyeglass lens according to the attributes of the wearer of the eyeglass lens.

4. The spectacle lens supply system according to claim 3, characterized in that, The spectral transmittance setting unit sets the spectral transmittance of the eyeglass lens based on the solar radiation intensity of the region where the eyeglass lens is used and the spectral transmittance of the wearer's eye.

5. The eyeglass lens supply system according to claim 3 or 4, characterized in that, The spectral transmittance setting unit sets the spectral transmittance of the eyeglass lens based on the relationships 1 to 3.

6. A method for supplying spectacle lenses, characterized in that, have: The spectral transmittance setting process sets the spectral transmittance of the eyeglass lens based on a relation selected from at least one of the following relationships. (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused. (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered. (3) The relationship between the wavelength of light and the irradiance that distinguishes whether the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells in the wearer of the eyeglass lens; The task of determining the content of the task is shared by material A, which reduces the transmittance of a specified wavelength range S, and material B, which reduces the transmittance of other specified wavelength ranges T.

7. A method for designing an eyeglass lens, characterized in that, have: The spectral transmittance setting process sets the spectral transmittance of the eyeglass lens based on a relation selected from at least one of the following relationships. (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused. (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered. (3) The relationship between the wavelength of light and the irradiance that distinguishes whether the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells in the wearer of the eyeglass lens; The task of determining the content of the task is shared by material A, which reduces the transmittance of a specified wavelength range S, and material B, which reduces the transmittance of other specified wavelength ranges T.

8. A method for manufacturing a spectacle lens, characterized in that, have: The spectral transmittance setting process sets the spectral transmittance of the eyeglass lens based on a relation selected from at least one of the following relationships. (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused. (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered. (3) The relationship between the wavelength of light and the irradiance that distinguishes whether the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells in the wearer of the eyeglass lens; The task of determining the content of the task is shared by material A, which reduces the transmittance of a specified wavelength range S, and material B, which reduces the transmittance of other specified wavelength ranges T. In the manufacturing process, materials A and B are determined using the aforementioned content to manufacture eyeglass lenses with a transmittance set by the aforementioned spectral transmittance setting process.

9. A program for a supply system of eyeglass lenses, wherein a computer functions as a spectral transmittance setting unit and a content determination unit, the spectral transmittance setting unit setting the spectral transmittance of the eyeglass lens based on a relation selected from at least one of the following relations: (1) The relationship between wavelength of light and irradiance that corresponds to the range of morphological changes in the eye cells of the wearer of the spectacle lens, and whether or not the changes in the morphology of the eye cells are caused. (2) The relationship between wavelength of light and irradiance that corresponds to the range 2 required for the migration ability of eye cells in the wearer of the spectacle lens, distinguishing whether the migration ability of eye cells is altered. (3) The relationship between the wavelength of light and the irradiance that distinguishes whether the infiltration of eye cells changes, corresponding to the range required for the infiltration of eye cells in the wearer of the eyeglass lens; The task of achieving the selected relationship is shared by material A, which reduces the transmittance of a specified range S, and material B, which reduces the transmittance of other specified ranges T.

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