Metal organic framework chiral separation membrane as well as preparation method and application thereof
By laying an aqueous solution of a specific component on a PVDF-based membrane to form a metal-organic framework structure, the problem of poor stability in the chiral separation of naproxen in existing membrane separation methods is solved, and a highly efficient and stable chiral separation effect is achieved.
Patent Information
- Application Number
- CN202511184979.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-08-22
- Publication Date
- 2025-11-28
AI Technical Summary
Existing membrane separation methods have poor stability in the chiral separation of naproxen, and are easily contaminated and aged, leading to a decline in separation performance.
A method for preparing chiral separation membranes using metal-organic frameworks was employed. This method involved laying an aqueous solution containing hydroxypropyl-β-cyclodextrin, sulfobutyl-β-cyclodextrin, N-ethylaniline, diphenyl sulfoxide, and alkali metal hydroxides onto a PVDF-based membrane to form a metal-organic framework structure. The high specific surface area and chiral control capability of the metal-organic framework, combined with the modification of hydroxypropyl and sulfobutyl groups, improved the membrane's stability and separation performance.
It achieves good separation performance and stability during the chiral resolution of naproxen, with a separation efficiency of 100% within 4 hours and maintaining high efficiency even after long-term use.