A composite rotator cuff patch and methods of making and using the same

By using a composite rotator cuff patch design with alternating structural and biological layers, the shortcomings of existing materials in terms of mechanical properties, degradation cycle, and biocompatibility are solved, achieving a highly efficient rotator cuff repair effect, promoting cell migration and healing, and reducing the risk of inflammation.

CN121129494BActive Publication Date: 2026-04-17SHANGHAI POLLAGEN MEDICAL MATERIALS CO LTD
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Patent Information

Application Number
CN202511666661.2
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-11-14
Publication Date
2026-04-17
Estimated Expiration
2045-11-14

AI Technical Summary

Technical Problem

Existing rotator cuff patch materials have shortcomings in terms of mechanical properties, degradation cycle, pore structure and biocompatibility, resulting in poor rotator cuff repair effects, slow postoperative recovery and the possibility of secondary damage.

Method used

The design employs alternating structural and biological layers. The structural layers are made of materials such as collagen, gelatin, collagen fibers, or silk fibroin, while the biological layers are made of materials such as collagen, gelatin, chitosan, or silk fibroin. A porous structure is formed through hot pressing, avoiding the use of chemical cross-linking agents and ensuring the biocompatibility and safety of the material.

Benefits of technology

It provides good mechanical support, promotes cell migration and healing, has a controllable degradation cycle, reduces the risk of inflammatory response, improves the biocompatibility and safety of the patch, and enhances tear resistance and mechanical support.

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Abstract

The present application relates to a kind of composite rotator cuff patch and its preparation method and application, belong to the field of biomaterials technology.The structure layer and biological layer are all biological medical materials, do not need to introduce crosslinking agent, and by the structure layer and biological layer alternate composite design, avoid the problem that traditional synthetic material is not degradable or short degradation period, with controllable degradation period, improve the tear resistance and mechanical support of patch, effectively reduce the risk of inflammatory response, improve the biocompatibility and safety of patch, finally realize the applicability and effect of improving composite rotator cuff patch in clinical application.
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