A human-like fibronectin and its dermal filling composition

By preparing human-like fibronectin and its dermal filler composition, the biocompatibility and durability issues of traditional dermal fillers have been solved, achieving a highly effective improvement in skin wrinkles and demonstrating significant medical and cosmetic applications.

CN121673396BActive Publication Date: 2026-06-19JILIN PROVINCE LANPU HAOYE TECH CO LTD +1

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
JILIN PROVINCE LANPU HAOYE TECH CO LTD
Filing Date
2026-02-12
Publication Date
2026-06-19

AI Technical Summary

Technical Problem

Traditional dermal fillers have limitations in terms of biocompatibility, durability, and ability to promote tissue regeneration, making them difficult to effectively improve skin wrinkles.

Method used

Human-derived fibronectin and its dermal filler composition are used, including human-derived fibronectin, human-derived collagen, sodium hyaluronate and pharmaceutical excipients. Human-derived fibronectin is prepared by genetic engineering and combined with other ingredients to form a dermal filler with high biocompatibility and long-term support.

Benefits of technology

It provides long-term support to skin tissue, significantly improves skin wrinkles caused by external environmental factors and age, and has important medical and cosmetic application value.

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Abstract

This invention relates to the field of protein engineering technology, specifically disclosing a human-like fibronectin and its skin-filling composition. The invention provides a recombinant human-like fibronectin with the amino acid sequence shown in SEQ ID No. 1, which can promote the adhesion or migration of dermal fibroblasts and maintain the long-term stability of its molecular structure in subcutaneous tissue. The skin-filling composition containing this recombinant human-like fibronectin can provide a supporting and filling function through subcutaneous injection, thereby achieving the purpose of correcting wrinkles.
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