Nasal spray device

Abstract

The invention relates to a nasal spray device. The nasal spray device comprises a regulation and control shell, a movable element and a spray unit. The regulation and control shell comprises an air blowing structure, a nose socket and an airflow channel communicating the air blowing structure with the nose socket. The movable element is movably arranged on the regulation and control shell, the movable element is matched with the inner wall of the regulation and control shell to open or close the airflow channel, and the movable element closes the airflow channel under the action of airflow input by the blowing structure; the spraying unit can be mounted on the regulation and control shell in a manner of being close to or far away from the nose bell mouth, and the spraying unit is driven to spray medicine to the nose bell mouth and trigger the movable element to open the airflow channel in the process of moving towards the nose bell mouth. Through the arrangement, when the nasal spray device sprays atomized medicine to a user through the nose bell mouth, auxiliary airflow flowing to the airflow channel is introduced through the air blowing structure, the auxiliary airflow flows into the nasal cavity of the user through the nose bell mouth of the airflow channel, and the initial speed and the movement track of the atomized medicine are effectively regulated and controlled; the medicine is promoted to be transported and deposited to a target area at the deep part of the nasal cavity.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, and in particular to a nasal spray device. Background Technology

[0002] Nasal spray devices are used for intranasal drug delivery. Nasal delivery leverages the rich blood supply and thin epithelial barrier of the nasal mucosa, allowing for rapid drug absorption into the systemic circulation. This effectively avoids gastrointestinal degradation and the first-pass effect in the liver, thus improving bioavailability. It offers advantages such as rapid onset of action, non-invasiveness, and high patient compliance. Furthermore, nasal delivery can achieve centrally targeted delivery of some drugs through the olfactory and trigeminal nerve pathways, bypassing the blood-brain barrier. In addition, the relatively small dosage required for nasal delivery helps reduce systemic adverse reactions. Therefore, nasal delivery is widely used in the medical field.

[0003] Nasal medication is typically administered via a nasal spray device that produces atomized particles that act on the user's nasal cavity. The particle size D of the atomized particles produced by the nasal spray device is... 50 Typically larger than 20 μm, these particles exhibit extremely strong motion inertia. Due to the complex anatomical structure and narrow nasal valve area within the nasal cavity, these high-inertia particles are mainly deposited through inertial impaction. Their trajectory is highly dependent on the initial jet vector, which makes it easy for the drug to be impacted and trapped in a straight line when passing through the nasal vestibule. This makes it difficult for the drug to cross the anterior end of the nasal turbinate and enter the deep target area, severely limiting the effective distribution range and systemic absorption efficiency of the drug. Summary of the Invention

[0004] Therefore, it is necessary to provide a nasal spray device to address the problem that current nasal spray devices result in a large amount of drug deposition in the nasal vestibule and anterior segment of the inferior turbinate, leading to low effective deposition in the target area.

[0005] A nasal spray device, the nasal spray device comprising a control shell, a movable element, and a spray unit, wherein: The control shell includes an air blowing structure, a nose inlet, and an airflow channel connecting the air blowing structure and the nose inlet. The movable element is movably disposed on the control shell, and the movable element cooperates with the inner wall of the control shell to open or close the airflow channel. The movable element is used to close the airflow channel under the action of the airflow input by the blowing structure. The spray unit can be installed on the control housing near or away from the nasal inlet. The process of driving the spray unit to move toward the nasal inlet is used to spray medicine into the nasal inlet and trigger the active element to open the airflow channel.

[0006] In one embodiment, the inner wall of the airflow channel has a stop surface that is adapted to fit the outer surface of the movable element. Under the action of the airflow input by the blowing structure, the movable element moves to the stop surface to close the airflow channel.

[0007] In one embodiment, the active element has a smooth outer surface.

[0008] In one embodiment, the control shell includes a shell with an inner cavity, a mouthpiece disposed in the shell, and a movable channel connecting the mouthpiece and the inner cavity, wherein the end of the mouthpiece facing away from the shell forms an air blowing structure connected to the movable channel; The movable element is movably disposed in the movable channel, and the inner wall of the movable channel includes a stop surface adapted to the outer surface of the movable element.

[0009] In one embodiment, the inner wall of the active channel further includes a guide surface that extends from the air blowing structure toward the stop surface; Under the action of the airflow input by the blowing structure, the movable element moves along the guide surface to the stop surface.

[0010] In one embodiment, the mouth holder has a first channel extending through its opposite ends, and the housing has a second channel connecting the outside and the inner cavity, the first channel and the second channel forming the movable channel; The inner wall of the first channel near the side of the second channel, and / or the inner wall of the second channel near the side of the first channel, form the stop surface.

[0011] In one embodiment, the control shell includes a shell having an inner cavity and an air blowing structure and a nose port communicating with the inner cavity; The spray unit can be installed in the inner cavity closer to or further away from the nose socket. During the process of driving the spray unit to move toward the nose socket, the outer wall of the spray unit is used to push the movable element away from the stop surface to open the airflow channel.

[0012] In one embodiment, when the movable element is at the stop surface, a portion of the movable element is located in the inner cavity, and the movable element is on the movement path of the spray unit.

[0013] In one embodiment, the control housing further includes a limiting drive member disposed in the inner cavity, the limiting drive member being used to limit the travel of the spray unit and trigger the spray unit to spray the drug.

[0014] In one embodiment, the limiting drive has a limiting cavity, and the spray unit has a docking member that extends at least partially into the limiting cavity. The cavity wall of the limiting cavity is used to restrict the movement of the docking member, thereby limiting the travel distance of the spray unit.

[0015] In one embodiment, the arrangement direction of the spray unit and the nose port is a first direction, the cavity wall of the limiting cavity has a first limiting wall and a second limiting wall disposed opposite to each other along the first direction, and the docking member has a first docking surface and a second docking surface connected to each other. The spray unit has a first position and a second position. When the spray unit is in the first position, the second mating surface is supported by the second limiting wall. When the spray unit is in the second position, the first mating surface abuts against the first limiting wall.

[0016] In one embodiment, the spray unit includes a liquid supply module and a nozzle connected to the liquid supply module, wherein: The liquid supply module is used to store the drug and, when moving relative to the nozzle, allows the drug to flow to the nozzle; The nozzle is used to spray the drug onto the nasal inlet. The nozzle is provided with the docking member. When the docking member abuts against the cavity wall of the limiting cavity as the spray unit moves, the liquid supply module and the nozzle move relative to each other.

[0017] The aforementioned nasal spray device, by setting up a drive spray unit to move towards the nasal inlet, sprays medication into the inlet and also triggers a moving element to open the airflow channel. This achieves simultaneous spraying of atomized medication to the user through the nasal inlet and the introduction of auxiliary airflow into the airflow channel through the blowing structure. As the auxiliary airflow flows into the nasal cavity of different users through the nasal inlet of the airflow channel, it effectively regulates the initial velocity and trajectory of the atomized medication, reducing deposition in the anterior nasal region caused by inertial impact, thereby significantly promoting the transport and deposition of medication to the target area deep within the nasal cavity. Furthermore, it helps reduce the impact of individual nasal cavity structural differences on the drug delivery effect, thus achieving a more stable and controllable drug delivery effect. Attached Figure Description

[0018] The accompanying drawings, which form part of this application, are used to provide a further understanding of this application. The illustrative embodiments of this application and their descriptions are used to explain this application and do not constitute an undue limitation of this application.

[0019] To more clearly illustrate the technical solutions in the embodiments of this application, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0020] Figure 1 This is a schematic diagram of the structure of a nasal spray device provided in an embodiment of this application, in which a movable element closes the airflow channel under the action of airflow.

[0021] Figure 2 for Figure 1 A schematic diagram of the external structure of the nasal spray device.

[0022] Figure 3 for Figure 2 A cross-sectional view of the nasal spray device along the C-plane.

[0023] Figure 4 for Figure 3 A magnified schematic diagram of the structure at point A in the middle.

[0024] Figure 5 This is a schematic diagram of the movement of a movable element along a guide surface in a nasal spray device provided in an embodiment of this application.

[0025] Figure 6 This is an exploded view of the structure of a nasal spray device provided in an embodiment of this application.

[0026] Figure 7 This is an exploded view of the nasal spray device provided in one embodiment of this application.

[0027] Figure 8 This is a schematic diagram of the structure of a nasal spray device provided in an embodiment of this application, showing the movement of the moving element engaging with the stop surface.

[0028] Figure 9 This is a schematic diagram of the structure of the nasal spray device provided in an embodiment of this application, showing the cooperation between the docking member and the limiting cavity.

[0029] Figure 10 for Figure 9 Enlarged schematic diagram of the structure at point B.

[0030] Figure 11 This is a schematic diagram of the structure of a nasal spray device provided in an embodiment of this application, in which the spray unit sprays the drug and triggers an active element to open the airflow channel.

[0031] Figure 12 for Figure 11 A magnified schematic diagram of the structure at point C.

[0032] Explanation of reference numerals in the attached figures 10. Nasal spray device; 100. Control shell; 110. Mouth support; 111. First channel; 112. Air blowing structure; 120. Nose support; 121. Nose support opening; 130. Airflow channel; 131. Movable channel; 132. Stop surface; 133. Guide surface; 140. Shell; 141. Inner cavity; 142. Second channel; 143. First body; 144. Second body; 145. Insert; 146. Slot; 150. Protrusion; 160. Groove; 170. Limiting drive component; 171. Limiting cavity; 172. First limiting wall; 173. Second limiting wall; 200, Moving element; 200a, First moving element; 200b, Second moving element; 210, Outer surface; 300, Spray unit; 310, Liquid supply module; 311, Medicine bottle; 312, Pump assembly; 3121, Suction tube; 3122, First guide surface; 3123, Second guide surface; 313, Actuator; 313a, First actuator; 313b, Second actuator; 320, Connecting part; 321, First connecting surface; 322, Second connecting surface; 330, Nozzle; 331, Drain port; 331a, First drain port; 331b, Second drain port; 340, Seal. Detailed Implementation

[0033] To make the above-mentioned objectives, features, and advantages of this application more apparent and understandable, the specific embodiments of this application are described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of this application. However, this application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this application. Therefore, this application is not limited to the specific embodiments disclosed below.

[0034] In the description of this application, it should be understood that if terms such as "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential" appear, these terms indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.

[0035] Furthermore, where the terms "first" and "second" appear, these terms are for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined with "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, where the term "multiple" appears, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0036] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0037] The technical solutions provided by the embodiments of the present invention are described below with reference to the accompanying drawings.

[0038] like Figure 1 As shown, one embodiment of this application provides a nasal spray device 10 for nasal drug delivery. The nasal spray device 10 includes a control shell 100, a moving element 200, and a spray unit 300.

[0039] The control housing 100 includes an air blowing structure 112, a nose port 121, and an airflow channel 130 connecting the air blowing structure 112 and the nose port 121. A movable element 200 is movably disposed within the control housing 100. The movable element 200 cooperates with the inner wall of the control housing 100 to open or close the airflow channel 130. The movable element 200 is used to close the airflow channel 130 under the action of the airflow input from the air blowing structure 112. In actual use, the user blows air through the air blowing structure 112. The blown airflow acts on the movable element 200, causing the movable element 200 to move within the control housing 100 to a position that matches its inner wall, thereby sealing the airflow channel 130.

[0040] The spray unit 300 can be mounted on the control housing 100 either close to or away from the nose port 121. During the process of driving the spray unit 300 towards the nose port 121, the spray unit 300 sprays medication into the nose port 121 and triggers the movable element 200 to open the airflow channel 130. In actual use, as the spray unit 300 moves towards the nose port 121, it pushes the movable element 200 away from the inner wall of the control housing 100 that is adapted to the movable element 200, thereby opening the airflow channel 130.

[0041] In the aforementioned nasal spray device 10, the spray unit 300 is driven to move towards the nasal inlet 121. During this process, the spray unit 300 sprays medication into the nasal inlet 121, and the spray unit 300 also triggers the active element 200 to open the airflow channel 130. This achieves the simultaneous spraying of atomized medication to the user through the nasal inlet 121 and the introduction of auxiliary airflow into the airflow channel 130 via the blowing structure 112. As the auxiliary airflow flows into the nasal cavity of different users through the nasal inlet 121 of the airflow channel 130, on the one hand, the auxiliary airflow can effectively regulate the initial speed and trajectory of the atomized medication, reducing deposition in the anterior nasal cavity region caused by inertial impact, thereby significantly promoting the transport and deposition of medication to the target area deep within the nasal cavity; on the other hand, it helps to reduce the impact of individual differences in nasal cavity structure on the drug delivery effect, thereby achieving a more stable and controllable drug delivery effect.

[0042] Combination Figure 2 , Figure 3 and Figure 4 As shown, in order to achieve the engagement of the movable element 200 with the inner wall of the control housing 100 to close the airflow channel 130, in some embodiments, the inner wall of the airflow channel 130 has a stop surface 132, which is adapted to fit the outer surface 210 of the movable element 200. It should be understood that, in the initial state, the movable element 200 and the stop surface 132 of the airflow channel 130 have a certain travel distance, and airflow can flow within the airflow channel 130.

[0043] When a user inputs airflow into the airflow channel 130 through the air blowing structure 112, the movable element 200 moves to the stop surface 132 under the action of the airflow input through the air blowing structure 112. The outer surface 210 of the movable element 200 and the stop surface 132 come into contact to form a sealing fit, cutting off the path for the airflow to continue entering the airflow channel 130, thereby closing the airflow channel 130. At this time, the movable element 200 is the first movable element 200a whose movement is restricted.

[0044] In a preferred embodiment, the movable element 200 is one of a movable sphere or a movable cylinder, that is, the movable element 200 has a smooth outer surface 210. However, it should be noted that the movable element 200 is not limited to the movable sphere or movable cylinder mentioned above, and can also be any geometric shape such as a movable polyhedron.

[0045] That is, the outer surface 210 of the moving element 200 is not limited to a smooth plane or a smooth curved surface. The outer surface 210 of the moving element 200 can also be a rough surface with unevenness. The shape of the stop surface 132 can match the outer surface 210 of the moving element 200 so that the moving element 200 and the stop surface 132 form a continuous sealing line or sealing surface to close the airflow channel 130.

[0046] Preferably, the movable element 200 has a smooth outer surface 210 to prevent the movable element 200 from damaging the inner wall of the airflow channel 130.

[0047] In order for the movable element 200 to move smoothly to the stop surface 132 under the action of the airflow input by the blowing structure 112, in some embodiments, the control shell 100 includes a shell 140 having an inner cavity 141, a mouthpiece 110 disposed in the shell 140, and a movable channel 131 connecting the mouthpiece 110 and the inner cavity 141. The end of the mouthpiece 110 away from the shell 140 forms a blowing structure 112 that communicates with the movable channel 131. In actual use, the user places the mouthpiece 110 in the mouth and blows air into the movable channel 131 through the blowing structure 112 of the mouthpiece 110.

[0048] The movable element 200 is movably disposed in the movable channel 131, and the inner wall of the movable channel 131 includes a stop surface 132 adapted to the outer surface 210 of the movable element 200. In a specific configuration, the nose port 121 is connected to the movable channel 131 and the blowing structure 112 through the communicating cavity 141 to form an airflow channel 130.

[0049] With the above settings, when the user blows air into the active channel 131 through the blowing structure 112, the active element 200 moves to the stop surface 132 of the active channel 131 under the action of the airflow input by the blowing structure 112, cutting off the path of the airflow to continue entering the airflow channel 130 through the active channel 131, thereby closing the airflow channel 130.

[0050] It should also be noted that in this state, due to the obstruction of the user's exhaled airflow, the airflow pressure in the nasopharynx increases, and the airflow channel connecting the nasal cavity and oral cavity will be closed by the soft palate, thereby blocking the drug sprayed by the spray unit 300 from entering the lower respiratory tract.

[0051] In one embodiment, to facilitate the design of the nasal inlet 121, the control shell 100 further includes a nasal inlet 120 disposed on the shell 140. The nasal inlet 120 has a hollow structure communicating with the inner cavity 141, and the end of the nasal inlet 120 away from the shell 140 forms the nasal inlet 121. In actual use, the nasal inlet 120 is placed in the user's nasal cavity, and the nasal inlet 120 forms an airtight connection with the nasal cavity.

[0052] With the above settings, during the process of driving the spray unit 300 to move toward the nasal inlet 121, the spray unit 300 sprays the drug toward the nasal inlet 121 and triggers the active element 200 to leave the stop surface 132 to open the airflow channel 130. The auxiliary airflow in the airflow channel 130 enters the nasal cavity through the nasal inlet 120. The airflow carries the drug to adapt to the nasal cavity of different users, so that the drug is transported and deposited in the target area deep in the nasal cavity. This helps to reduce the impact of individual differences in nasal cavity structure on the drug delivery effect, thereby achieving a more stable and controllable drug delivery effect.

[0053] In some embodiments, the inner wall of the active channel 131 further includes a guide surface 133, which extends from the blowing structure 112 toward the stop surface 132. The guide surface 133 is used to guide the movement of the active element 200. Under the action of the airflow input by the blowing structure 112, the active element 200 moves along the guide surface 133 to the stop surface 132.

[0054] Combination Figure 5 As shown, it should be noted that when the user does not input airflow into the active channel 131 through the blowing structure 112, the active element 200 can reciprocate on the guide surface 133. At this time, the active element 200 is the second active element 200b that can move freely. At this time, the active channel 131 allows airflow to enter, and the airflow channel 130 connecting the blowing structure 112 and the nose port 121 also remains unobstructed.

[0055] It is important to emphasize that even when the user does not input airflow into the active channel 131 through the blowing structure 112, the active element 200 can still move freely from the guide surface 133 into the stop surface 132. During the user's blowing operation, to ensure that the active element 200 moves to the stop surface 132 under the action of airflow, the outer surface of the active element 200 engages with the stop surface 132 in a self-locking manner, thereby closing the airflow channel 130 to maintain intranasal pressure.

[0056] It is easy to understand that the structure jointly constructed by the moving element 200 and the stop surface 132 forms a simplified valve structure. This valve structure has self-actuating characteristics; it does not rely on external power components such as springs or electronic actuators, but only on the airflow generated by the user's exhalation to create a pneumatic self-locking structure between the moving element 200 and the stop surface 132. This design simplifies mechanical complexity while ensuring the synchronization of the valve structure's opening and closing with the user's breathing actions.

[0057] To prevent the movable element 200 from falling out of the nasal spray device 10 from the blowing structure 112, the blowing structure 112 is hollow, and the inner diameter of the hollow blowing structure 112 is smaller than the size of the movable element 200.

[0058] Based on this, combined Figure 6 and Figure 7 As shown, to facilitate the installation of the movable element 200 into the movable channel 131, the bearing 110 and the housing 140 are detachably connected, allowing the movable element 200 to be smoothly installed onto the stop surface 132 of the movable channel 131. In a specific configuration, one of the protrusion 150 and the groove 160 is installed in the bearing 110, and the other is installed in the housing 140.

[0059] Combination Figure 8 As shown, in order to facilitate the use of the spray unit 300 to trigger the movable element 200 to open the airflow channel 130, in some embodiments, the control housing 100 includes a housing 140 having an inner cavity 141 and an air blowing structure 112 and a nose port 121 communicating with the inner cavity 141. The spray unit 300 can be installed in the inner cavity 141 closer to or further away from the nose port 121. During the process of driving the spray unit 300 to move toward the nose port 121, the outer wall of the spray unit 300 is used to push the movable element 200 away from the stop surface 132 to open the airflow channel 130.

[0060] With the above configuration, the process of the movable element 200 opening the airflow channel 130 is controlled by the guidance of the outer wall of the spray unit 300. Specifically, during the process of driving the spray unit 300 to move towards the nose port 121, the movable element 200 is mechanically guided by the characteristic contour of the spray unit 300 itself. Without the introduction of additional components, this integrated design achieves precise valve linkage control without increasing the number of parts.

[0061] It should be noted that the outer wall of the spray unit 300 is used to push the movable element 200 toward the blowing structure 112, so that the movable element 200 leaves the stop surface 132 and the movable element 200 will return to the guide surface 133, making it convenient for the movable element 200 to be used again.

[0062] In order to facilitate the outer wall of the spray unit 300 to push the movable element 200 away from the stop surface 132, in some embodiments, when the movable element 200 is at the stop surface 132, part of the movable element 200 is located in the inner cavity 141 and the movable element 200 is on the moving path of the spray unit 300.

[0063] See again Figure 7In order to allow a portion of the movable element 200 located on the stop surface 132 to be situated within the inner cavity 141, in some embodiments, the bearing 110 has a first channel 111 extending through its opposite ends, and the housing 140 has a second channel 142 connecting the outside and the inner cavity 141. The first channel 111 and the second channel 142 form the movable channel 131. The inner wall of the first channel 111 near the side of the second channel 142, and / or the inner wall of the second channel 142 near the side of the first channel 111, form the stop surface 132.

[0064] With the above configuration, the stop surface 132 is formed on the inner wall of the movable channel 131 near the inner cavity 141. When the movable component moves to the stop surface 132, it is advantageous for part of the movable component to be located in the inner cavity 141.

[0065] See again Figure 8 In order to facilitate the movement of the spray unit 300 toward the nose socket 121, in some embodiments, the spray unit 300 has an actuating part 313 extending beyond the inner cavity 141. The user applies a force to the actuating part 313 toward the nose socket 121, thereby moving the spray unit 300 toward the nose socket 121. Specifically, the nose socket 121 and the spray unit 300 are aligned in a straight line. In actual use, the user applies an upward force to the bottom of the spray unit 300, causing the entire spray unit 300 to move toward the nose socket 121.

[0066] Combination Figure 7 , Figure 9 and Figure 10 As shown, in order to ensure that the spray unit 300 can be triggered to spray drugs during the process of the spray unit 300 moving towards the nose port 121, in some embodiments, the control shell 100 also includes a limiting drive member 170 disposed in the inner cavity 141. The limiting drive member 170 is used to limit the movement stroke of the spray unit 300 and trigger the spray unit 300 to spray drugs.

[0067] To facilitate the use of the limiting drive 170 to restrict the travel of the spray unit 300, the limiting drive 170 is specifically configured to have a limiting cavity 171. The spray unit 300 has a docking member 320, which at least partially extends into the limiting cavity 171. When the user drives the spray unit 300 toward the nose socket 121 via the actuation part 313, the docking member 320 moves within the limiting cavity 171 along the arrangement direction of the spray unit 300 and the nose socket 121. The cavity wall of the limiting cavity 171 is used to restrict the movement of the docking member 320, thereby limiting the travel of the spray unit 300.

[0068] More specifically, the arrangement direction of the spray unit 300 and the nose port 121 is a first direction, which is specifically a vertical direction in this application. The cavity wall of the limiting cavity 171 has a first limiting wall 172 and a second limiting wall 173 that are arranged opposite to each other along the first direction. The docking member 320 has a first docking surface 321 and a second docking surface 322 that are connected to each other. In a specific arrangement, the first docking surface 321 and the second docking surface 322 are arranged opposite to each other along the first direction.

[0069] The spray unit 300, which can move closer to or further away from the nose port 121, has a first position and a second position. When the spray unit 300 is in the first position, that is, the initial position, the second mating surface 322 is supported by the second limiting wall 173. When the user drives the spray unit 300 toward the nose port 121 through the actuation part 313, the second mating surface 322 leaves the second limiting wall 173, and the first mating surface 321 of the mating member 320 moves to abut against the first limiting wall 172. At this time, the spray unit 300 is in the second position.

[0070] With the above settings, as the spray unit 300 moves toward the nasal inlet 121, the spray unit 300 moves from the first position to the second position in the control shell 100, reducing the axial distance between the spray unit 300 and the target area in the nasal cavity. This physically increases the insertion depth of the spray unit 300 in the nasal cavity, which is beneficial for the precise spray distribution of the medicine in the target area of ​​the nasal cavity during subsequent spraying.

[0071] It should also be noted that the spray unit 300 falls back due to the gravity of the spray unit 300, that is, the spray unit 300 returns from the second position to the first position under the action of gravity.

[0072] See again Figure 7 , Figure 8 To facilitate the triggering of the spray unit 300 to spray medication by the limit drive 170, in some embodiments, the spray unit 300 includes a liquid supply module 310 and a nozzle 330 connected to the liquid supply module 310. The liquid supply module 310 has an actuating part 313 extending beyond the inner cavity 141. The liquid supply module 310 also stores medication, and when the liquid supply module 310 moves relative to the nozzle 330, it directs the medication towards the nozzle 330, which sprays the medication towards the nasal conduit 121. In a specific configuration, the nozzle 330 has a spray channel leading to the nasal conduit 121, with a drain port 331 at the end of the spray channel away from the liquid supply module 310. The medication is sprayed towards the nasal conduit 121 through the drain port 331 of the spray channel.

[0073] The nozzle 330 is provided with a docking member 320. When the docking member 320 moves with the spray unit 300, it abuts against the cavity wall of the limiting cavity 171. Specifically, when the spray unit 300 moves to the second position, the first limiting wall 172 of the limiting cavity 171 abuts against the first docking surface 321 of the docking member 320. That is, the first limiting wall 172 restricts the movement of the nozzle 330 by restricting the movement of the docking member 320. At this time, the user continuously applies a force toward the nose socket 121 through the actuating part 313, so that the liquid supply module 310 and the nozzle 330 move relative to each other, so that the medicine of the liquid supply module 310 is sprayed toward the nose socket 121 through the nozzle 330.

[0074] It should also be noted that during the relative movement between the liquid supply module 310 and the nozzle 330, the outer wall of the liquid supply module 310 is used to push the movable element 200 away from the stop surface 132 to open the airflow channel 130. Through the above arrangement, the drug delivery and airflow channel 130 of this application can operate simultaneously, which facilitates the hydrodynamic effect of the auxiliary airflow in the airflow channel 130, enhancing the carrying and deposition efficiency of atomized drug particles deep within the nasal cavity.

[0075] Combination Figure 11 and Figure 12 As shown, the specific process of using the nasal spray device 10 is as follows: The mouthpiece 110 is placed in the user's mouth, and the nosepiece 120 is placed in the user's nasal cavity. At this time, the movable element 200 is the first movable element 200a located in the movable channel 131. The user blows air into the movable channel 131 through the blowing structure 112 of the mouthpiece 110. The first movable element 200a in the movable channel 131 moves to the stop surface 132 under the action of airflow. At this time, the movable element 200b is the second movable element 200b that is tightly attached to the stop surface 132 to cut off the path of airflow to continue entering the movable channel 131, so that the airflow pressure in the nasopharynx increases. The airflow channel 130 connecting the nasal cavity and the oral cavity will be closed by the soft palate, thereby blocking the drug sprayed by the spray unit 300 from entering the lower respiratory tract. By applying a force toward the nasal inlet 121 to the actuator 313, the entire spray unit 300 moves from the first position to the second position. The discharge port 331 in the spray unit 300 changes from the first discharge port 331a in the initial position to the second discharge port 331b, which is closer to the nasal inlet 121. This reduces the axial distance between the discharge port 331 and the target area in the nasal cavity, thereby increasing the insertion depth of the discharge port 331 in the nasal cavity, which is beneficial for the delivery and deposition of drugs into the target area deep in the nasal cavity. When the spray unit 300 is in the second position, the first limiting wall 172 of the limiting cavity 171 in the housing 140 abuts against the first mating surface 321 of the mating member 320 in the nozzle 330 to restrict the movement of the nozzle 330. At this time, the actuator 313 applies a force toward the nose port 121, causing the liquid supply module 310 and the nozzle 330 to move relative to each other. Specifically, the actuator 313 of the liquid supply module 310 changes from the first actuator 313a in the first actuation position to the second actuator 313b in the second actuation position. During the movement of the liquid supply module 310, on the one hand, the outer wall of the liquid supply module 310 pushes the first movable element 200a away from the stop surface 132, so that the movable element 200 moves from the braking position located on the stop surface 132 to the movable position located on the guide surface 133, thereby opening the airflow channel 130; on the other hand, the drug inlet nozzle 330 of the liquid supply module 310 sprays the drug out in an atomized form through the discharge port 331 of the nozzle 330 under the action of airflow.

[0076] See again Figure 7 To facilitate the delivery of medication from the supply module 310 to the nozzle 330 when the supply module 310 and the nozzle 330 move relative to each other, in some embodiments, the supply module 310 includes a medicine bottle 311 for containing the medication and a pump assembly 312 installed on the medicine bottle 311. The pump assembly 312 is also connected to the nozzle 330. When the pump assembly 312 drives the medicine bottle 311 to move relative to the nozzle 330, the pump assembly 312 inputs the medication from the medicine bottle 311 into the nozzle 330. This is a mature prior art and will not be elaborated on here.

[0077] For ease of understanding, the pump assembly 312 is briefly described below. The pump assembly 312 includes a suction tube 3121, a metering valve, and a check valve. Under the action of the check valve, the suction tube 3121 can only draw the liquid from the medicine bottle 311 into the metering valve, preventing it from flowing back into the medicine bottle 311. When the pump assembly 312 moves upward relative to the nozzle 330, the spring of the metering valve is compressed, and the liquid in the metering valve is compressed into the swirling chamber of the nozzle 330. The inner wall of the swirling chamber is a swirling groove. According to the principle of swirling atomization, the liquid moves radially outward under the action of centrifugal force, extending into a liquid film on the rotating surface of the swirling groove. Centrifugal force overcomes the surface tension and viscosity of the liquid, causing the liquid film to continuously thin, detaching from the surface at the rotating edge to form a filamentous or ribbon-like structure. High-speed airflow or ambient gas interacts with the liquid filaments and ribbons, further breaking them into micron-sized droplets through gas-liquid shear force.

[0078] The outer wall of the pump assembly 312 is also used to trigger the movable element 200 to open the airflow passage 130. In one specific embodiment, the outer wall of the pump assembly 312 includes a first guide surface 3122 and a second guide surface 3123 connected to the first guide surface 3122. The first guide surface 3122 and / or the second guide surface 3123 are used to push the movable element 200 away from the stop surface 132 to open the airflow passage 130.

[0079] Specifically, in the initial state, the first guide surface 3122 and the second guide surface 3123 of the pump assembly 312 are spaced apart from the movable element 200. When the pump assembly 312 moves relative to the nozzle 330, the first guide surface 3122 and / or the second guide surface 3123 come into contact with the movable element 200. Guided by the characteristic contours of the first guide surface 3122 and / or the second guide surface 3123, the movable element 200 moves from the stop surface 132 to the guide surface 133.

[0080] To prevent airflow from entering the inner cavity 141 of the housing 140 from outside the airflow channel 130, a sealing element 340 is provided around the outer periphery of the medicine bottle 311. The sealing element 340 is used to seal the gap between the medicine bottle 311 and the cavity wall of the inner cavity 141. In a specific configuration, the sealing element 340 is preferably a sealing ring.

[0081] For ease of manufacture and installation, the housing 140 includes a first body 143 and a second body 144 that engages with the first body 143. Specifically, one of the insert 145 and the slot 146 is mounted on the first body 143, and the other is mounted on the second body 144. Preferably, a sealing element is also installed at the connection between the first body 143 and the second body 144 to prevent airflow from entering from there.

[0082] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0083] The embodiments described above are merely illustrative of several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this patent application should be determined by the appended claims.

Claims

1. A nasal spray device, characterized in that, The nasal spray device comprises a control shell, a movable element and a spray unit, wherein: The control shell comprises a blowing structure, a nose nozzle and an air flow channel connecting the blowing structure and the nose nozzle; The movable element is movably arranged in the control shell, and the movable element cooperates with the inner wall of the control shell to open or close the air flow channel, and the movable element is used to close the air flow channel under the action of the air flow input by the blowing structure; The spray unit can be installed in the control shell close to or away from the nose nozzle, and during the process of driving the spray unit to move towards the nose nozzle, the spray unit is used to spray the drug to the nose nozzle and trigger the movable element to open the air flow channel.

2. The nasal spray device of claim 1, wherein, The inner wall of the air flow channel has a stop surface which is adapted to the outer surface of the movable element, and under the action of the air flow input by the blowing structure, the movable element moves to the stop surface to close the air flow channel.

3. The nasal spray device of claim 1, wherein, The movable element has a smooth outer surface.

4. The nasal spray device of claim 1, wherein, The control shell comprises a shell having an inner cavity, a mouth nozzle arranged on the shell, and a movable channel connecting the mouth nozzle and the inner cavity, and the end of the mouth nozzle away from the shell forms a blowing structure connected with the movable channel; The movable element is movably arranged in the movable channel, and the inner wall of the movable channel comprises a stop surface adapted to the outer surface of the movable element.

5. The nasal spray device of claim 4, wherein, The inner wall of the movable channel further comprises a guide surface extending from the blowing structure to the stop surface; Under the action of the air flow input by the blowing structure, the movable element moves along the guide surface to the stop surface.

6. The nasal spray device of claim 5, wherein, The mouth nozzle is provided with a first channel penetrating through the opposite ends thereof, and the shell is provided with a second channel connecting the outside and the inner cavity, and the first channel and the second channel form the movable channel; The inner wall of the first channel close to the second channel, and / or the inner wall of the second channel close to the first channel form the stop surface.

7. The nasal spray device of claim 2, wherein, The control shell comprises a shell having an inner cavity, and a blowing structure and a nose nozzle connected with the inner cavity; The spray unit can be installed in the inner cavity close to or away from the nose nozzle, and during the process of driving the spray unit to move towards the nose nozzle, the outer wall of the spray unit is used to push the movable element away from the stop surface to open the air flow channel.

8. The nasal spray device of claim 7, wherein, When the movable element is in the stop surface, part of the movable element is located in the inner cavity, and the movable element is in the moving path of the spray unit.

9. The nasal spray device of claim 7, wherein, The control shell further comprises a limiting driving element arranged in the inner cavity, and the limiting driving element is used to limit the moving stroke of the spray unit and trigger the spray unit to spray the drug.

10. The nasal spray device of claim 9, wherein, The limiting driving element has a limiting cavity, and the spray unit has an interfacing element at least partially extending into the limiting cavity, and the cavity wall of the limiting cavity is used to limit the movement of the interfacing element to limit the moving stroke of the spray unit.

11. The nasal spray device of claim 10, wherein, The arrangement direction of the spray unit and the nosepiece is a first direction, the cavity wall of the limiting cavity has oppositely arranged first and second limiting walls along the first direction, and the abutting member has first and second abutting surfaces connected to each other; The spray unit has first and second positions, when the spray unit is located at the first position, the second abutting surface is carried on the second limiting wall, and when the spray unit is located at the second position, the first abutting surface abuts against the first limiting wall.

12. The nasal spray device of claim 10, wherein, The spray unit comprises a liquid supply module and a nozzle connected to the liquid supply module, wherein: The liquid supply module is used to store the medicine and make the medicine flow to the nozzle when the liquid supply module moves relative to the nozzle; The nozzle is used to spray the medicine to the nosepiece, and the abutting member is arranged on the nozzle, when the abutting member abuts against the cavity wall of the limiting cavity with the movement of the spray unit, the liquid supply module moves relative to the nozzle.

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