TEVAR branch stent operation branch artery positioning method and device

Abstract

The invention relates to the technical field of medical instruments, and discloses a TEVAR branch stent operation branch artery positioning method and device, and the method comprises the steps: morphologically measuring image data to determine thoracic aorta data, a baseline position and an opening cross section position of at least one branch artery, and measuring the opening cross section diameter of the branch artery; according to the thoracic aorta center line and the opening section position of the branch artery, the opening center point and center line of the branch artery and the opening direction relative to the aorta center line are determined; measuring the shortest distance from the opening center point of the branch artery to the section position of the proximal end of the thoracic aorta; and determining the opening section of the branch artery and the position of the branch artery on the thoracic aorta. According to the invention, information such as aorta data and branch artery data is obtained by using clinical medical image data, and then the positions and the opening diameters of the branch arteries are determined, so that the positions of the branch arteries are accurately positioned before an operation, and a proper branch artery stent is favorably manufactured and mounted.

Description

Technical Field

[0001] This invention relates to the field of medical device technology, specifically to a method and device for locating branch arteries in TEVAR branched stent surgery. Background Technology

[0002] Thoracic aortic diseases mainly include aortic aneurysms and aortic dissections, with a mortality rate as high as 94% to 100% after aortic rupture. For thoracic aortic diseases, open surgery and TEVAR (thoracic endovascular aortic repair) are the main methods for addressing this problem. Compared with traditional open surgery, TEVAR has a relatively lower mortality rate and complication rate. TEVAR is now considered a less invasive method for treating thoracic aortic diseases. However, to obtain a sufficient proximal landing area, TEVAR inevitably involves covering branch arteries to achieve good fixation of the stent graft. However, covering branch arteries can lead to blockage, causing poor blood flow and thus inducing related complications, increasing the risk of stroke, left arm ischemia, and spinal cord ischemia.

[0003] To address the issue of branch artery coverage and the associated risks of complications, three main surgical methods are currently employed: the chimney technique, the fenestration technique, and the branched stent technique. Each method has its advantages and disadvantages. The chimney technique requires the insertion of an additional stent, increasing surgical complexity and the risk of endoleak. The fenestration technique carries two potential risks: firstly, the pre-loaded catheter may become entangled in the scalloped strut; secondly, the use of snares and wires in the dental arch area can lead to the formation of small thrombi. The branched stent technique overcomes the drawbacks of the first two methods, but precise localization of the patient's branch arteries during stent customization is crucial to ensure proper stent placement. Summary of the Invention

[0004] In view of this, the present invention provides a method and device for locating branch arteries in TEVAR branched stent surgery to solve the problems of complex and time-consuming location of branch arteries in branched stent surgery.

[0005] In a first aspect, the present invention provides a method for locating branch arteries in TEVAR branched stent surgery, the method comprising:

[0006] Morphological measurements were performed on the imaging data to determine the thoracic aorta data, baseline position, and the opening cross-sectional position of at least one branch artery. The thoracic aorta data included: the thoracic aorta centerline, aortic segment length, proximal cross-sectional position, and distal cross-sectional position. The opening cross-sectional diameter of the branch artery was measured based on the opening cross-sectional position of the branch artery.

[0007] Based on the central line of the thoracic aorta and the location of the branch arteries' opening sections, determine the center point and central line of the branch arteries' openings, and then determine the opening direction of the branch arteries relative to the aortic central line based on the center point and central line of the branch arteries' openings.

[0008] Measure the shortest distance from the center point of the branch artery's opening to the proximal section of the thoracic aorta;

[0009] The opening section of the branch artery and its position on the thoracic aorta are determined based on the diameter of the branch artery's opening section, the shortest distance from the center point of the opening to the proximal section of the thoracic aorta, and the opening direction relative to the aortic centerline.

[0010] The TEVAR branch stent surgery branch artery localization method provided by this invention uses clinical medical imaging data to obtain information such as aortic data and branch artery data, and then determines the location and opening diameter of the branch arteries, so as to accurately locate the position of each branch artery before surgery, which is beneficial for the fabrication and installation of appropriate branch artery stents.

[0011] In one optional embodiment, the branch artery includes a first branch artery, a second branch artery, and a third branch artery. Determining the opening direction of the branch artery relative to the aortic centerline based on its opening center point and centerline includes:

[0012] The center point and center line of the first branch artery opening are determined based on the location of the central line of the thoracic aorta and the opening section of the first branch artery. The intersection of the center line of the first branch artery and the central line of the thoracic aorta is taken as the origin of the reference line. The direction of the reference line is the direction of the first branch artery center line pointing to the distal end. The section where the center line of the first branch artery is located is the reference plane. The reference plane is perpendicular to the central line of the thoracic aorta. The first angle of the first branch artery is recorded as 0. Within the reference plane, the angle in the clockwise direction is positive and the angle in the counterclockwise direction is negative, based on the reference line direction.

[0013] The center point and center line of the second branch artery opening are determined based on the location of the opening section of the thoracic aorta and the second branch artery. The intersection of the center line of the second branch artery and the center line of the thoracic aorta is taken as the second origin. The direction from the center line of the second branch artery to the distal end is taken as the second direction. The section where the center line of the second branch artery is located is taken as the second plane. The second plane is perpendicular to the center line of the thoracic aorta. The second angle between the center line of the second branch artery and the reference line is measured.

[0014] The center point and center line of the third branch artery are determined based on the location of the opening section of the central line of the thoracic aorta and the opening section of the third branch artery. The intersection of the center line of the third branch artery and the central line of the thoracic aorta is taken as the third origin. The direction from the center line of the third branch artery to the distal end is taken as the third direction. The section where the center line of the third branch artery is located is the third plane. The third plane is perpendicular to the center line of the thoracic aorta. The third angle between the center line of the third branch artery and the reference line is measured.

[0015] The TEVAR branch stent surgery branch artery localization method provided by this invention, by selecting a suitable reference plane and determining the relative position and direction of the three branch arteries according to the reference plane, is conducive to accurately locating the position of each branch artery.

[0016] In one alternative implementation, the baseline is located on the thoracic aorta, at the proximal section of the opening of the first branch artery, and the plane of the baseline is perpendicular to the tangent of the centerline of the thoracic aorta.

[0017] The TEVAR branch stent surgery branch artery localization method provided by the present invention, by selecting a suitable baseline position to determine the aortic segment, is beneficial for determining the stent installation position and the opening position and direction of each branch artery.

[0018] In one alternative implementation, morphological measurements of the imaging data are performed to determine the thoracic aorta data, including:

[0019] Select a reference point on the thoracic aorta to automatically determine the centerline of the thoracic aorta;

[0020] Select a proximal section and a distal section on the thoracic aorta. The distance from the proximal section to the heart is less than the distance from the baseline to the heart. The distance from the proximal section along the centerline of the thoracic aorta to the baseline is the first preset distance. The distance from the distal section to the heart is greater than the distance from the baseline to the heart. The distance from the distal section along the centerline of the thoracic aorta to the baseline is the second preset distance.

[0021] The length of the aortic segment is the sum of the first preset distance and the second preset distance.

[0022] The TEVAR branched stent surgery branch artery localization method provided by this invention determines the thoracic aorta data by performing morphological measurements on imaging data. The determination method is simple and accurate.

[0023] In one optional implementation, measuring the diameter of the branch artery's opening section based on its location includes:

[0024] Measure the maximum and minimum diameters of the branch artery's opening section, and take their average value as the diameter of the branch artery's opening section.

[0025] The TEVAR branch stent surgery branch artery localization method provided by this invention uses the average of the maximum and minimum diameters of the branch artery opening cross-section as the diameter of the branch artery opening cross-section. The calculation is accurate, and the resulting stent opening is neither too large nor too small, ensuring smooth blood flow under the premise of successful stent implantation.

[0026] In one alternative implementation, measuring the shortest distance from the center point of the branch artery's opening to the proximal section of the thoracic aorta includes:

[0027] The thoracic aorta is cut at the proximal and distal sections, and the outer surface of the thoracic aorta is unfolded along the centerline into a planar diagram. A pair of opposite sides of the planar diagram are the perimeter of the proximal and distal sections of the thoracic aorta, respectively.

[0028] The vertical distance from the center point of the branch artery's opening to the perimeter of the proximal section on the plan view is the shortest distance from the center point of the branch artery's opening to the proximal section of the thoracic aorta.

[0029] In one alternative implementation, the perimeter of the proximal section is greater than the perimeter of the distal section, and in a plan view, the vertical distance from the center point of the branch artery's opening to the perimeter of the proximal section is less than the vertical distance from the center point of the branch artery's opening to the perimeter of the distal section.

[0030] The TEVAR branch stent surgery branch artery localization method provided by this invention accurately locates the proximal and distal cross sections, thereby determining the vertical distance from the center point of the branch artery's opening to the perimeter of the proximal cross section, which can accurately locate the opening position of the branch artery on the aorta.

[0031] Secondly, embodiments of the present invention provide a TEVAR branched stent surgical branch artery localization device, the device comprising:

[0032] The data acquisition module is used to perform morphological measurements on the imaging data to determine the thoracic aorta data, baseline position, and the opening section position of at least one branch artery. The thoracic aorta data includes: the thoracic aorta centerline, aortic segment length, proximal section position, and distal section position. The opening section diameter of the branch artery is measured based on the opening section position of the branch artery.

[0033] The opening direction determination module is used to determine the opening center point and centerline of the branch artery based on the centerline of the thoracic aorta and the opening cross-section position of the branch artery, and to determine the opening direction of the branch artery relative to the centerline of the aorta based on the opening center point and centerline of the branch artery.

[0034] The shortest distance measurement module is used to measure the shortest distance from the center point of the branch artery's opening to the proximal section of the thoracic aorta;

[0035] The branch artery location determination module is used to determine the branch artery's opening section and its position on the thoracic aorta based on the branch artery's opening section diameter, the shortest distance from the opening center point to the proximal section of the thoracic aorta, and its opening direction relative to the aortic centerline.

[0036] Thirdly, the present invention provides a computer device, comprising: a memory and a processor, the memory and the processor being communicatively connected to each other, the memory storing computer instructions, and the processor executing the computer instructions to perform the method described in the first aspect or any corresponding embodiment thereof.

[0037] Fourthly, the present invention provides a computer-readable storage medium storing computer instructions for causing a computer to perform the method described in the first aspect or any corresponding embodiment thereof. Attached Figure Description

[0038] To more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0039] Figure 1 This is a schematic flowchart of the TEVAR branched stent surgery branch artery localization method according to an embodiment of the present invention;

[0040] Figure 2 This is a flowchart illustrating another method for locating branch arteries in TEVAR branched stent surgery according to an embodiment of the present invention;

[0041] Figure 3 This is a schematic diagram of the thoracic aorta in the TEVAR branched stent surgery branch artery localization method according to an embodiment of the present invention;

[0042] Figure 4 This is a schematic diagram of the cross-sectional positions of the openings of three branch arteries in the TEVAR branched stent surgery branch artery localization method according to an embodiment of the present invention;

[0043] Figure 5 This is a schematic diagram of the circumferential direction angles of three branch arteries in the TEVAR branched stent surgery branch artery localization method according to an embodiment of the present invention;

[0044] Figure 6This is a plan view of the outer surface of the thoracic aorta along the centerline direction in the TEVAR branched stent surgery branch artery localization method according to an embodiment of the present invention;

[0045] Figure 7 This is a schematic diagram of a three-dimensional cone corresponding to the thoracic aorta in the TEVAR branched stent surgery branch artery localization method according to an embodiment of the present invention;

[0046] Figure 8 This is a two-dimensional sector diagram of the outer surface of the thoracic aorta after it has been unfolded in the TEVAR branched stent surgery branch artery localization method according to an embodiment of the present invention.

[0047] Figure 9 This is a three-dimensional model of the thoracic aorta printed in the verification test of the TEVAR branched stent surgery branch artery localization method according to an embodiment of the present invention;

[0048] Figure 10 This is a structural block diagram of the TEVAR branched stent surgical branch artery positioning device according to an embodiment of the present invention;

[0049] Figure 11 This is a schematic diagram of the hardware structure of a computer device according to an embodiment of the present invention. Detailed Implementation

[0050] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0051] This invention provides a method for locating branch arteries in TEVAR branched stent surgery. By performing morphological measurements on imaging data, the aortic and branch artery data are determined to achieve accurate preoperative location of the branch arteries.

[0052] According to an embodiment of the present invention, a method for locating branch arteries in TEVAR branched stent surgery is provided. It should be noted that the steps shown in the flowchart in the accompanying drawings can be executed in a computer system such as a set of computer-executable instructions. Furthermore, although a logical order is shown in the flowchart, in some cases, the steps shown or described may be executed in a different order than that shown here.

[0053] This embodiment provides a method for locating branch arteries in TEVAR branched stent surgery, which can be used with the aforementioned computer equipment. Figure 1This is a flowchart of the branch artery localization method for TEVAR branched stent surgery according to an embodiment of the present invention, as follows: Figure 1 As shown, the process includes the following steps:

[0054] Step S101: Morphological measurements are performed on the imaging data to determine the thoracic aorta data, baseline position, and the opening section position of at least one branch artery. The thoracic aorta data includes: the thoracic aorta centerline, aortic segment length, proximal section position, and distal section position. The opening section diameter of the branch artery is measured based on the opening section position of the branch artery.

[0055] Specifically, before surgery, imaging data of the corresponding patient is acquired. This data must meet the following requirements: scan slice thickness between 1 and 2 mm, scan slice distance of 1 mm, scan window completely encompassing the chest, selection of the arterial phase, and contrast-enhanced CT. The qualified imaging data is then imported into software specifically designed for vascular simulation and surgical planning (such as 3Mensio WorkstationVascular, this is just one example and not a limitation) for morphological measurement. 3Mensio WorkstationVascular can segment and reconstruct blood vessels from medical imaging data (such as CT and MRI), generating a high-quality 3D vascular model. Surgeons can visually observe the structure and morphological characteristics of the blood vessels and quickly locate the lesion site through rotation, scaling, and magnification. The target thoracic aorta is selected based on the lesion site, and its origin and termination points are marked. The centerline of the thoracic aorta is determined based on these points and can be manually fine-tuned to ensure that the selected target thoracic aorta completely covers the lesion area.

[0056] The aortic information obtained through morphological measurements includes: the proximal diameter of the aorta, the distal diameter of the aorta, and the length of the aortic segment; the branch artery information includes: the circumferential angle, the distance from the proximal end, and the diameter of the branch artery.

[0057] Step S102: Based on the central line of the thoracic aorta and the location of the branch artery's opening section, determine the center point and central line of the branch artery's opening, and determine the opening direction of the branch artery relative to the aortic central line based on the center point and central line of the branch artery's opening.

[0058] Specifically, in a 3D model of a blood vessel, the location of the branch artery's opening cross-section can be visually determined. Based on the centerline of the thoracic aorta, experienced medical personnel select the center point and centerline of the branch artery's opening according to preset standards. A cross-section of the branch artery is then drawn through this center point and centerline, ensuring the cross-section is perpendicular to the centerline of the thoracic aorta. If there are multiple branch arteries, the centerline direction of one branch artery can be used as the twelve o'clock position, meaning the corresponding cross-section is used as a reference plane. The angle between the cross-sections of the remaining branch arteries and the reference plane is then determined, thus determining the relative angle of the centerlines of each branch artery. The opening direction of each branch artery relative to the aortic centerline is the circumferential angle of each branch artery.

[0059] Step S103: Measure the shortest distance from the center point of the branch artery's opening to the proximal section of the thoracic aorta.

[0060] Specifically, the shortest distance from the center point of the branch artery's opening to the proximal section of the thoracic aorta is measured to determine the opening position of the branch artery on the thoracic aorta. The distance from the center point of the branch artery's opening to the proximal section of the thoracic aorta can be the intersection of the extension of the branch artery's centerline and the thoracic aorta's centerline, or the distance along the thoracic aorta to the proximal section of the thoracic aorta. This is just an example, but not a limitation.

[0061] Step S104: Determine the opening section of the branch artery and its position on the thoracic aorta based on the diameter of the branch artery's opening section, the shortest distance from the center point of the opening to the proximal section of the thoracic aorta, and its opening direction relative to the aortic centerline.

[0062] Specifically, the size of the branch artery's opening is determined based on the diameter of its opening section. The location and direction of the branch artery's opening on the thoracic aorta are determined based on the shortest distance from the center point of the opening to the proximal section of the thoracic aorta and its opening direction relative to the aortic centerline, thereby achieving accurate opening of the branch artery on the thoracic aorta.

[0063] The TEVAR branch stent surgery branch artery localization method provided in this embodiment uses clinical medical imaging data to obtain information such as aortic data and branch artery data, and then determines the location and opening diameter of the branch arteries, so as to accurately locate the position of each branch artery before surgery, which is beneficial for the fabrication and installation of appropriate branch artery stents.

[0064] This embodiment provides a method for locating branch arteries in TEVAR branched stent surgery, which can be used with the aforementioned computer equipment. Figure 2 This is a flowchart of the branch artery localization method for TEVAR branched stent surgery according to an embodiment of the present invention, as follows: Figure 2As shown, the process includes the following steps:

[0065] Step S201 involves performing morphological measurements on the imaging data to determine the thoracic aorta data, baseline position, and the opening cross-sectional position of at least one branch artery. The thoracic aorta data includes: the thoracic aorta centerline, aortic segment length, proximal cross-sectional position, and distal cross-sectional position. The opening cross-sectional diameter of the branch artery is measured based on its opening cross-sectional position. Specifically, step S201 includes:

[0066] Step S2011: Select a reference point on the thoracic aorta and automatically determine the centerline of the thoracic aorta.

[0067] Specifically, based on the location of the patient's lesion, the target thoracic aorta is selected, and the starting and ending points of the center line are manually selected on the thoracic aorta. Based on the starting and ending points, the software can automatically generate the center line of the thoracic aorta. The automatically generated center line may have slight deviations, which can be fine-tuned manually to ensure that the selected center line completely covers the lesion area.

[0068] Step S2012: Select a proximal section and a distal section on the thoracic aorta. The distance from the proximal section to the heart is less than the distance from the baseline to the heart. The distance from the proximal section along the centerline of the thoracic aorta to the baseline is the first preset distance. The distance from the distal section to the heart is greater than the distance from the baseline to the heart. The distance from the distal section along the centerline of the thoracic aorta to the baseline is the second preset distance.

[0069] Specifically, determine the location of the proximal section of the branch artery opening (e.g. Figure 3 (The plane where point B is shown is used to establish a baseline, which is perpendicular to the tangent of the thoracic aorta's central line. In actual stent implantation, the stent's initial position must be placed in a healthy aortic segment, with a first or second pre-set distance between the stent and the lesion site. Generally, the first pre-set distance proximally is 20mm, and the second pre-set distance distally is 180mm. This is just an example and not a limitation. Therefore, the proximal section of the thoracic aorta is selected at a section 20mm from the baseline curve (e.g., ...). Figure 3 The plane where point A is shown is selected, and the location of the distal end section is chosen at a distance of 180mm from the baseline curve (e.g., the plane where point A is located). Figure 3 (The plane containing point C shown).

[0070] Once the positions of the proximal and distal cross-sections are determined, the maximum and minimum diameters of the proximal cross-section can be automatically measured, and their average value can be calculated as the diameter of the proximal cross-section. Similarly, the diameter of the distal cross-section can be determined by measuring its maximum and minimum diameters.

[0071] Step S2013: The length of the aortic segment is the sum of the first preset distance and the second preset distance.

[0072] Specifically, the selected aortic segment length is 20mm + 180mm = 200mm.

[0073] Step S2014: Measure the maximum and minimum diameters of the branch artery's opening section, and take their average value as the diameter of the branch artery's opening section.

[0074] Specifically, for the opening cross-section of each branch artery, its maximum and minimum diameters can be automatically measured, and the average of the maximum and minimum diameters can be calculated as the opening cross-section diameter of the corresponding branch artery.

[0075] The TEVAR branch stent surgery branch artery localization method provided in this embodiment determines the thoracic aorta data by performing morphological measurements on imaging data. The determination method is simple and accurate. The average of the maximum and minimum diameters of the branch artery opening section is used as the diameter of the branch artery opening section. The calculation is accurate, and the obtained stent opening is neither too large nor too small, ensuring smooth blood flow under the premise of successful stent implantation.

[0076] Step S202: Based on the central line of the thoracic aorta and the location of the branch artery's opening section, determine the center point and central line of the branch artery's opening, and determine the opening direction of the branch artery relative to the aortic central line based on the center point and central line of the branch artery's opening.

[0077] Specifically, the branch artery includes a first branch artery, a second branch artery, and a third branch artery, and step S202 above includes:

[0078] Step S2021: Determine the center point and centerline of the opening of the first branch artery based on the central line of the thoracic aorta and the location of the opening section of the first branch artery. Take the intersection of the centerline of the first branch artery and the central line of the thoracic aorta as the origin of the reference line, and take the direction of the reference line from the centerline of the first branch artery toward the distal end as the direction of the reference line. The section where the centerline of the first branch artery is located is the reference plane. The reference plane is perpendicular to the central line of the thoracic aorta. Record the first angle of the first branch artery as 0. Within the reference plane, with the direction of the reference line as the reference, the clockwise angle is a positive value, and the counterclockwise angle is a negative value.

[0079] Specifically, the first branch artery is generally the brachiocephalic trunk, the second branch artery is the left common carotid artery, and the third branch artery is the left subclavian artery. Figure 4 The diagram shows the location of the opening sections of the three branch arteries. After determining the location of the opening sections of each branch artery, the diameter of the corresponding opening section can be automatically measured and calculated. Step S2014 has been explained above and will not be repeated here.

[0080] To determine the opening location of each branch artery, it is also necessary to determine the opening direction of each branch artery relative to the thoracic aorta. Since the three branch arteries are all on the same aorta, the relative positions of the opening directions of the three branch arteries can be determined first. Then, during the placement of the stent in the operation, fine adjustments can be made to ensure that the opening position and direction of the three branch arteries match the actual blood vessel.

[0081] Based on the location of the opening sections of the thoracic aorta and brachiocephalic trunk, experienced medical personnel manually select the center point and centerline of the brachiocephalic trunk opening on the software. The origin is the intersection of the brachiocephalic trunk opening centerline and the thoracic aorta centerline. The direction along the brachiocephalic trunk centerline towards the distal end is the reference line direction. The section containing the brachiocephalic trunk centerline is the reference plane, perpendicular to the thoracic aorta centerline. At this point, the reference line direction is recorded as the 12 o'clock direction, meaning the angle of the brachiocephalic trunk centerline is 0 degrees. For example... Figure 5 As shown, the three circles represent the cross-sections of the thoracic aorta at the center points of the openings of the three branch arteries along the central line of the thoracic aorta, and the arrows point in the direction of the central line of the three branch arteries.

[0082] In one alternative implementation, the baseline is located on the thoracic aorta, at the proximal section of the opening of the first branch artery, and the plane of the baseline is perpendicular to the tangent of the centerline of the thoracic aorta.

[0083] The TEVAR branch stent surgery branch artery localization method provided in this embodiment, by selecting a suitable baseline position to determine the aortic segment, is beneficial for determining the stent installation position and the opening position and direction of each branch artery.

[0084] Step S2022: Determine the center point and center line of the opening of the second branch artery based on the position of the opening section of the thoracic aorta and the second branch artery. Take the intersection of the center line of the second branch artery and the center line of the thoracic aorta as the second origin, the direction from the center line of the second branch artery to the distal end as the second direction, the section where the center line of the second branch artery is located as the second plane, the second plane is perpendicular to the center line of the thoracic aorta, and measure the second angle between the center line of the second branch artery and the reference line.

[0085] Specifically, when determining the second included angle, the second plane and the reference plane can be placed in the same plane, so that the second origin coincides with the origin of the reference line, such as... Figure 5 As shown, the second angle of the left common carotid artery can be determined based on the reference line, and is marked as α.

[0086] Step S2023: Determine the center point and center line of the opening of the third branch artery based on the central line of the thoracic aorta and the location of the opening section of the third branch artery. Take the intersection of the center line of the third branch artery and the central line of the thoracic aorta as the third origin, the direction along the center line of the third branch artery pointing to the distal end as the third direction, the section where the center line of the third branch artery is located as the third plane, the third plane is perpendicular to the central line of the thoracic aorta, and measure the third angle between the center line of the third branch artery and the reference line.

[0087] Specifically, when determining the third included angle, the third plane and the reference plane can be placed in the same plane, so that the third origin coincides with the origin of the reference line, such as... Figure 5 As shown, the third angle of the left subclavian artery can be determined based on the reference line, and is marked as β.

[0088] The TEVAR branch stent surgery branch artery localization method provided in this embodiment, by selecting a suitable reference plane and determining the relative position and direction of the three branch arteries based on the reference plane, is conducive to accurately locating the position of each branch artery.

[0089] Step S203: Measure the shortest distance from the center point of the branch artery opening to the proximal section of the thoracic aorta.

[0090] Specifically, step S203 includes:

[0091] Step S2031: The thoracic aorta is cut at the proximal and distal cross-sections, and the outer surface of the thoracic aorta is unfolded along the centerline into a planar diagram. A pair of opposite sides of the planar diagram are the perimeter of the proximal and distal cross-sections of the thoracic aorta, respectively.

[0092] In one alternative implementation, the perimeter of the proximal section is greater than the perimeter of the distal section, and in a plan view, the vertical distance from the center point of the branch artery's opening to the perimeter of the proximal section is less than the vertical distance from the center point of the branch artery's opening to the perimeter of the distal section.

[0093] Step S2032: Measure the vertical distance from the center point of the branch artery's opening to the perimeter of the proximal section on the plan view. This distance is the shortest distance from the center point of the branch artery's opening to the proximal section of the thoracic aorta.

[0094] Specifically, such as Figure 6 The figure shows a planar view of the outer surface of the thoracic aorta unfolded along the centerline. In the planar view, a pair of opposite sides represent the perimeter of the proximal and distal sections of the thoracic aorta, respectively. The three circles represent the opening sections of the three branch arteries. The perpendicular distance from the center of the three circles to the perimeter of the proximal section is the shortest distance from the center point of the opening of the corresponding branch artery to the position of the proximal section of the thoracic aorta.

[0095] The TEVAR branch stent surgery branch artery localization method provided in this embodiment accurately locates the proximal and distal cross sections, thereby determining the vertical distance from the center point of the branch artery's opening to the perimeter of the proximal cross section, which can accurately locate the opening position of the branch artery on the aorta.

[0096] Step S204: Determine the opening section of the branch artery and its position on the thoracic aorta based on the diameter of the branch artery's opening section, the shortest distance from the center point of the opening to the proximal section of the thoracic aorta, and its opening direction relative to the aortic centerline.

[0097] Specifically, after determining the locations of the three branch arteries, the aortic and branch artery information is input into the software. The aortic information includes the proximal diameter, distal diameter, and length of the aortic segment. The branch artery information includes the circumferential angle, distance from the proximal end, and opening diameter of the branch artery. This yields a planar diagram of the aorta and branch arteries. Before stent implantation, the stent is released, and the planar diagram is printed on A4 paper, sterilized, and placed over the aortic stent. According to this embodiment, the branch artery locations, represented by the three small circles in the planar diagram, represent the three branch arteries. Along the edges of the three small circles, three "openings" are made on the aortic stent using a scalpel or similar tool, and the stent is then retracted. During the procedure, the stent is released only after reaching the lesion location. If the "opening" position is not aligned with the branch artery opening, the surgeon adjusts the stent position by translation and rotation until it is aligned. Then, a guidewire is implanted through the "opening," completing the release of the branch artery stent.

[0098] Specifically, based on the difference in blood vessel diameter, a shorter blood vessel (the blood vessel from the proximal end to the distal end of the thoracic aorta in the above embodiment) is assumed to be a frustum model. Then, the three-dimensional frustum is unfolded along its center line onto a two-dimensional plane. The position and size information of the main blood vessel and branch arteries obtained clinically is projected onto the two-dimensional plane, and the position and size information of the main blood vessel and branch arteries on the two-dimensional plane is obtained through mathematical derivation.

[0099] Based on the three-dimensional frustum, its corresponding three-dimensional cone can be obtained, such as... Figure 7 The diagram shows a three-dimensional cone. Given the distal diameter D1, proximal diameter D2, and height H of the blood vessel, we can obtain:

[0100]

[0101] The generatrix lengths R1 and R2 of the cone are respectively:

[0102]

[0103] The central angle of the sector unfolded corresponding to the current cone is:

[0104]

[0105] Figure 8 The diagram shows a two-dimensional sector after the cone has been unfolded. The key geometric information is derived as follows:

[0106] A and B are the endpoints of the distal main blood vessel section unfolded into a two-dimensional circular arc, and C and D are the endpoints of the proximal main blood vessel section unfolded into a two-dimensional circular arc.

[0107] The coordinates of vertices A and B are:

[0108]

[0109] BX = -AX, BY = -AY (6)

[0110] The coordinates of vertices C and D are:

[0111]

[0112] DX = -CX, DY = -CY (8)

[0113] Figure 8 The small circle in the diagram represents the location of the branch artery. In polar coordinates, the radius R3 of this location can be expressed as:

[0114] R3 = R2 - h (9)

[0115] Where h is the input height of the small circle, i.e., the distance from the near end. The angle of the small circle in the circumferential direction... It can be represented as:

[0116]

[0117] Therefore, the coordinates of the small circle in the rectangular coordinate system can be expressed as:

[0118]

[0119]

[0120] To further verify the effectiveness of the embodiments of the present invention, the thoracic aorta in the above embodiments was reconstructed in three dimensions and then 3D printed to obtain a three-dimensional model of the thoracic aorta (e.g., Figure 9 (as shown), and then the above embodiment obtained Figure 6 The PDF file shown was printed and then fitted onto the inner wall of the 3D model of the thoracic aorta. The results showed that the brachiocephalic trunk, left common carotid artery, and left subclavian artery were all aligned with the inner wall of the model. Figure 6 The three branch arteries marked in the image are in the same position.

[0121] This embodiment also provides a TEVAR branched stent surgery branch artery positioning device, which is used to implement the above embodiments and preferred embodiments, and will not be repeated as already described. As used below, the term "module" can be a combination of software and / or hardware that implements a predetermined function. Although the device described in the following embodiments is preferably implemented in software, hardware implementation, or a combination of software and hardware, is also possible and contemplated.

[0122] This embodiment provides a TEVAR branched stent surgery branch artery positioning device, such as... Figure 10 As shown, it includes:

[0123] The data acquisition module 1001 is used to perform morphological measurements on the image data to determine the thoracic aorta data, baseline position, and the opening section position of at least one branch artery. The thoracic aorta data includes: the thoracic aorta centerline, aortic segment length, proximal section position, and distal section position. The opening section diameter of the branch artery is measured based on the opening section position of the branch artery.

[0124] The opening direction determination module 1002 is used to determine the opening center point and centerline of the branch artery based on the centerline of the thoracic aorta and the opening section position of the branch artery, and to determine the opening direction of the branch artery relative to the centerline of the aorta based on the opening center point and centerline of the branch artery.

[0125] The shortest distance measurement module 1003 is used to measure the shortest distance from the center point of the branch artery opening to the proximal section of the thoracic aorta.

[0126] The branch artery location determination module 1004 is used to determine the opening section of the branch artery and its position on the thoracic aorta based on the diameter of the branch artery's opening section, the shortest distance from the center point of the opening to the proximal section of the thoracic aorta, and its opening direction relative to the aortic centerline.

[0127] In some optional implementations, the data acquisition module 1001 includes:

[0128] The aortic centerline determination unit is used to select a reference point on the thoracic aorta and automatically determine the centerline of the thoracic aorta.

[0129] The distance determination unit is used to select a proximal section and a distal section on the thoracic aorta. The distance from the proximal section to the heart is less than the distance from the baseline position to the heart. The distance from the proximal section along the centerline of the thoracic aorta to the baseline position is the first preset distance. The distance from the distal section to the heart is greater than the distance from the baseline position to the heart. The distance from the distal section along the centerline of the thoracic aorta to the baseline position is the second preset distance.

[0130] The length calculation unit is used to calculate the aortic segment length as the sum of a first preset distance and a second preset distance.

[0131] In some alternative implementations, the opening direction determination module 1002 includes:

[0132] The reference determination unit is used to determine the center point and centerline of the opening of the first branch artery based on the centerline of the thoracic aorta and the location of the opening section of the first branch artery. The intersection of the centerline of the first branch artery and the centerline of the thoracic aorta is taken as the origin of the reference line, and the direction from the centerline of the first branch artery to the distal end is taken as the direction of the reference line. The section where the centerline of the first branch artery is located is the reference plane. The reference plane is perpendicular to the centerline of the thoracic aorta. The first included angle of the first branch artery is recorded as 0. Within the reference plane, with the direction of the reference line as the reference, the included angle in the clockwise direction is a positive value, and the included angle in the counterclockwise direction is a negative value.

[0133] The second angle determination unit is used to determine the center point and center line of the opening of the second branch artery based on the position of the opening section of the thoracic aorta center line and the second branch artery. The intersection of the center line of the second branch artery and the center line of the thoracic aorta is taken as the second origin, the direction from the center line of the second branch artery to the distal end is taken as the second direction, the section where the center line of the second branch artery is located is taken as the second plane, the second plane is perpendicular to the center line of the thoracic aorta, and the second angle between the center line of the second branch artery and the reference line is measured.

[0134] The third angle determination unit is used to determine the center point and center line of the opening of the third branch artery based on the center line of the thoracic aorta and the opening section position of the third branch artery. The intersection of the center line of the third branch artery and the center line of the thoracic aorta is taken as the third origin, the direction from the center line of the third branch artery to the distal end is taken as the third direction, the section where the center line of the third branch artery is located is taken as the third plane, the third plane is perpendicular to the center line of the thoracic aorta, and the third angle between the center line of the third branch artery and the reference line is measured.

[0135] In some alternative implementations, the shortest distance measurement module 1003 includes:

[0136] The artery unfolding unit is used to cut the thoracic aorta at the proximal and distal cross-sectional positions and unfold the outer surface of the thoracic aorta along the centerline into a planar diagram. A pair of opposite sides of the planar diagram are the perimeter of the proximal and distal cross-sections of the thoracic aorta, respectively.

[0137] The distance measurement unit is used to measure the vertical distance from the center point of the branch artery's opening to the perimeter of the proximal section on the plan view, which is the shortest distance from the center point of the branch artery's opening to the proximal section of the thoracic aorta.

[0138] Further functional descriptions of the above modules and units are the same as those in the corresponding embodiments described above, and will not be repeated here.

[0139] In this embodiment, the TEVAR branch stent surgical branch artery positioning device is presented in the form of a functional unit. Here, a unit refers to an ASIC (Application Specific Integrated Circuit) circuit, a processor and memory that execute one or more software or fixed programs, and / or other devices that can provide the above functions.

[0140] This invention also provides a computer device having the above-described features. Figure 10 The TEVAR branched stent surgical branch artery positioning device shown.

[0141] Please see Figure 11 , Figure 11 This is a schematic diagram of the structure of a computer device provided in an optional embodiment of the present invention, such as... Figure 11 As shown, the computer device includes one or more processors 10, memory 20, and interfaces for connecting the components, including high-speed interfaces and low-speed interfaces. The components communicate with each other via different buses and can be mounted on a common motherboard or otherwise installed as needed. The processors can process instructions executed within the computer device, including instructions stored in or on memory to display graphical information of a GUI on external input / output devices (such as display devices coupled to the interfaces). In some alternative implementations, multiple processors and / or multiple buses can be used with multiple memories and multiple memory modules, if desired. Similarly, multiple computer devices can be connected, each providing some of the necessary operations (e.g., as a server array, a group of blade servers, or a multiprocessor system). Figure 11 Take a processor 10 as an example.

[0142] Processor 10 may be a central processing unit, a network processor, or a combination thereof. Processor 10 may further include a hardware chip. The hardware chip may be an application-specific integrated circuit (ASIC), a programmable logic device (PLD), or a combination thereof. The programmable logic device may be a complex programmable logic device (CAMP), a field-programmable gate array (FPGA), a general-purpose array logic (GDA), or any combination thereof.

[0143] The memory 20 stores instructions executable by at least one processor 10 to cause the at least one processor 10 to perform the method shown in the above embodiments.

[0144] The memory 20 may include a program storage area and a data storage area. The program storage area may store the operating system and applications required for at least one function; the data storage area may store data created based on the use of the computer device. Furthermore, the memory 20 may include high-speed random access memory and may also include non-transitory memory, such as at least one disk storage device, flash memory device, or other non-transitory solid-state storage device. In some alternative embodiments, the memory 20 may optionally include memory remotely located relative to the processor 10, and these remote memories may be connected to the computer device via a network. Examples of such networks include, but are not limited to, the Internet, intranets, local area networks, mobile communication networks, and combinations thereof.

[0145] The memory 20 may include volatile memory, such as random access memory; the memory may also include non-volatile memory, such as flash memory, hard disk or solid-state drive; the memory 20 may also include a combination of the above types of memory.

[0146] The computer device also includes a communication interface 30 for communicating with other devices or communication networks.

[0147] This invention also provides a computer-readable storage medium. The methods described above according to embodiments of the invention can be implemented in hardware or firmware, or implemented as computer code that can be recorded on a storage medium, or implemented as computer code downloaded via a network and originally stored on a remote storage medium or a non-transitory machine-readable storage medium and then stored on a local storage medium. Thus, the methods described herein can be processed by software stored on a storage medium using a general-purpose computer, a dedicated processor, or programmable or dedicated hardware. The storage medium can be a magnetic disk, optical disk, read-only memory, random access memory, flash memory, hard disk, or solid-state drive, etc.; further, the storage medium can also include combinations of the above types of memory. It is understood that computers, processors, microprocessor controllers, or programmable hardware include storage components capable of storing or receiving software or computer code, which, when accessed and executed by the computer, processor, or hardware, implements the methods shown in the above embodiments.

[0148] Although embodiments of the invention have been described in conjunction with the accompanying drawings, those skilled in the art can make various modifications and variations without departing from the spirit and scope of the invention, and such modifications and variations all fall within the scope defined by the appended claims.

Claims

1. A method for locating branch arteries in TEVAR branched stent surgery, characterized in that, The method includes: Morphological measurements of imaging data are performed to determine the data of the thoracic aorta, baseline position, and the opening cross-sectional position of at least one branch artery. The thoracic aorta data includes: the thoracic aorta centerline, aortic segment length, proximal cross-sectional position, and distal cross-sectional position. The opening cross-sectional diameter of the branch artery is measured based on the opening cross-sectional position of the branch artery. Based on the central line of the thoracic aorta and the location of the opening section of the branch artery, determine the opening center point and central line of the branch artery, and determine the opening direction of the branch artery relative to the central line of the aorta based on the opening center point and central line of the branch artery. Measure the shortest distance from the center point of the branch artery's opening to the proximal section of the thoracic aorta; The opening section of the branch artery and its position on the thoracic aorta are determined based on the diameter of the branch artery's opening section, the shortest distance from the center point of the opening to the proximal section of the thoracic aorta, and the opening direction relative to the aortic centerline.

2. The method according to claim 1, characterized in that, The branch artery includes a first branch artery, a second branch artery, and a third branch artery. The opening direction of the branch artery relative to the aortic centerline is determined based on the center point and centerline of its opening, including: The center point and center line of the opening of the first branch artery are determined based on the position of the opening cross section of the central line of the thoracic aorta and the opening of the first branch artery. The intersection of the center line of the first branch artery and the central line of the thoracic aorta is taken as the origin of the reference line. The direction of the reference line is the direction of the first branch artery from the center line to the distal end. The cross section where the center line of the first branch artery is located is the reference plane. The reference plane is perpendicular to the central line of the thoracic aorta. The first angle of the first branch artery is recorded as 0. Within the reference plane, the angle in the clockwise direction is positive and the angle in the counterclockwise direction is negative, based on the direction of the reference line. The center point and center line of the second branch artery opening are determined based on the location of the opening section of the thoracic aorta center line and the second branch artery opening section. The intersection of the center line of the second branch artery and the thoracic aorta center line is taken as the second origin. The direction from the center line of the second branch artery to the distal end is taken as the second direction. The section where the center line of the second branch artery is located is taken as the second plane. The second plane is perpendicular to the center line of the thoracic aorta. The second angle between the center line of the second branch artery and the reference line is measured. The center point and center line of the opening of the third branch artery are determined based on the central line of the thoracic aorta and the location of the opening section of the third branch artery. The intersection of the center line of the third branch artery and the central line of the thoracic aorta is taken as the third origin. The direction from the center line of the third branch artery to the distal end is taken as the third direction. The section where the center line of the third branch artery is located is the third plane. The third plane is perpendicular to the center line of the thoracic aorta. The third angle between the center line of the third branch artery and the reference line is measured.

3. The method according to claim 2, characterized in that, The baseline is located on the thoracic aorta, at the proximal section of the opening of the first branch artery, and the plane of the baseline is perpendicular to the tangent of the center line of the thoracic aorta.

4. The method according to claim 3, characterized in that, The steps for determining thoracic aortic data through morphological measurements of imaging data include: Select a reference point on the thoracic aorta to automatically determine the centerline of the thoracic aorta; A proximal section and a distal section are selected on the thoracic aorta. The distance from the proximal section to the heart is less than the distance from the baseline position to the heart. The distance from the proximal section along the centerline of the thoracic aorta to the baseline position is a first preset distance. The distance from the distal section to the heart is greater than the distance from the baseline position to the heart. The distance from the distal section along the centerline of the thoracic aorta to the baseline position is a second preset distance. The length of the aortic segment is the sum of a first preset distance and a second preset distance.

5. The method according to claim 1, characterized in that, Measuring the diameter of the opening section of the branch artery based on its opening section location includes: Measure the maximum and minimum diameters of the opening section of the branch artery, and take their average value as the opening section diameter of the branch artery.

6. The method according to claim 1, characterized in that, The measurement of the shortest distance from the center point of the branch artery's opening to the proximal section of the thoracic aorta includes: The thoracic aorta is cut at the proximal and distal cross-sections, and the outer surface of the thoracic aorta is unfolded along the centerline into a planar diagram. A pair of opposite sides of the planar diagram are the perimeter of the proximal and distal cross-sections of the thoracic aorta, respectively. The vertical distance from the center point of the branch artery's opening on the plan view to the perimeter of the proximal section is the shortest distance from the center point of the branch artery's opening to the proximal section of the thoracic aorta.

7. The method according to claim 6, characterized in that, The perimeter of the proximal section is greater than the perimeter of the distal section, and on the plan view, the vertical distance from the center point of the branch artery's opening to the perimeter of the proximal section is less than the vertical distance from the center point of the branch artery's opening to the perimeter of the distal section.

8. A TEVAR branched stent surgical branch artery positioning device, characterized in that, The device includes: The data acquisition module is used to perform morphological measurements on image data to determine the thoracic aorta data, baseline position, and the opening cross-sectional position of at least one branch artery. The thoracic aorta data includes: the thoracic aorta centerline, aortic segment length, proximal cross-sectional position, and distal cross-sectional position. The opening cross-sectional diameter of the branch artery is measured based on the opening cross-sectional position of the branch artery. The opening direction determination module is used to determine the opening center point and center line of the branch artery based on the center line of the thoracic aorta and the opening cross-section position of the branch artery, and to determine the opening direction of the branch artery relative to the center line of the aorta based on the opening center point and center line of the branch artery. The shortest distance measurement module is used to measure the shortest distance from the center point of the branch artery's opening to the proximal section of the thoracic aorta; The branch artery location determination module is used to determine the opening section of the branch artery and its position on the thoracic aorta based on the diameter of the opening section, the shortest distance from the center point of the opening to the proximal section of the thoracic aorta, and the opening direction relative to the aortic centerline.

9. A computer device, characterized in that, include: A memory and a processor, the memory and the processor being communicatively connected to each other, the memory storing computer instructions, the processor executing the computer instructions to perform the method of any one of claims 1 to 7.

10. A computer-readable storage medium, characterized in that, The computer-readable storage medium stores computer instructions for causing the computer to perform the method of any one of claims 1 to 7.

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