Medical defoaming agent and preparation method thereof

By using a special emulsification process to prepare medical defoamers, and combining the synergistic effects of multiple components, the problems of single function and poor stability of existing defoamers are solved. This achieves efficient defoaming, long-lasting lubrication and anesthetic effects, improving the effectiveness of gastroscopy and patient comfort.

CN122124289APending Publication Date: 2026-06-02ANHUI ZHONGKE MEDICAL INSTR CO LTD
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Patent Information

Application Number
CN202610164093.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-02-05
Publication Date
2026-06-02

AI Technical Summary

Technical Problem

Existing medical defoamers have limited functions, poor lubrication and anesthetic effects, insufficient defoaming efficiency, and poor system stability, which affect the effectiveness of gastroscopy and patient comfort.

Method used

A combination of dimethicone, Span 60, Span 80, Tween 80, glycerin, lidocaine hydrochloride, potassium sorbate, and mono-fatty acid glycerides is used to prepare a uniform and delicate paste-like oil phase and aqueous phase through a special emulsification process, forming a stable emulsion that achieves synergistic effects of lubrication, anesthesia, and defoaming.

Benefits of technology

It achieves efficient defoaming, long-lasting lubrication, and reliable anesthetic effects, improving the clarity of gastroscopy and patient comfort, while ensuring the physical and chemical stability of the formulation.

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Abstract

The invention relates to the field of medical instruments, and particularly discloses a medical defoaming agent and a preparation method thereof. The existing medical defoaming agent has the main functions of lubricating and eliminating gastrointestinal foam, but has a single function or a poor synergistic effect, so that the definition of gastroscopy, the comfort of a patient and the operation efficiency are influenced. The medical defoaming agent disclosed by the invention is prepared from the following components in percentage by weight: 1 to 5 percent of dimethyl silicone oil, 0 to 1 percent of span 60, 0 to 0.5 percent of span 80, 5 to 10 percent of Tween 80, 5 to 10 percent of glycerol, 0.5 to 1 percent of lidocaine hydrochloride, 0 to 0.5 percent of potassium sorbate, 0.2 to 1 percent of fatty acid monoglyceride and the balance of purified water. According to the formula, simethicone with different viscosities and a specific proportion is compounded to serve as a core lubricating and defoaming matrix; a non-ionic composite emulsification system of span and Tween is adopted, so that stable emulsification of an oil phase and a water phase is ensured; fatty acid monoglyceride is introduced as a physical defoaming aid and a system stabilizer; and lidocaine hydrochloride is used for realizing surface anesthesia.
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