Phytobacterium plantarum LPU3 and application thereof in relieving hyperuricemia

By developing a combination of Lactobacillus plantarum LPU3 and its inactivated, dead, and postbiotic cells, the problems of single function and stability of existing strains have been solved, achieving multiple effects of uric acid regulation and intestinal improvement, and enhancing the stability and safety of the product.

CN122168473APending Publication Date: 2026-06-09SHENZHEN DUNXING HEALTH TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202610320537.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-03-17
Publication Date
2026-06-09

AI Technical Summary

Technical Problem

Existing strains of *Lactobacillus plantarum* have single functional targets for uric acid regulation, poor storage stability, weak tolerance to gastric acid, pose an infection risk, and have insufficient development of stable products.

Method used

We developed a strain of Lactobacillus plantarum LPU3 and its inactivated, dead, and postbiotic forms, which, through various combinations, achieve multiple functions such as uric acid degradation, metabolic enzyme inhibition, intestinal flora improvement, and reduction of renal oxidative stress.

Benefits of technology

It provides multiple functions of uric acid degradation and metabolic enzyme inhibition, improves gut microbiota balance, reduces kidney oxidative stress induced by hyperuricemia, and enhances the storage stability and applicability of the strain.

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Abstract

The invention belongs to the technical field of plant lactobacillus, and particularly relates to plant lactobacillus LPU3 and application thereof in relieving hyperuricemia. The plant lactobacillus LPU3 has the capacity of degrading uric acid in vitro, the capacity of inhibiting xanthine oxidase in vitro, the intervention effect on hyperuricemia and the inhibiting effect on metabolic enzymes, and has the functions of improving kidney injury caused by the hyperuricemia, improving kidney inflammation and oxidative stress caused by the hyperuricemia and improving intestinal flora disorder caused by the hyperuricemia.
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