A fully automatic integrated production equipment for single blister dry powder inhaler

Abstract

The application relates to the technical field of medical packaging production equipment, and discloses a full-automatic integrated production equipment for single-bubble dry powder inhalers, which comprises a machine table, a filling assembly, a heat-sealing assembly, a pushing assembly and a cutting assembly are sequentially arranged on the top of the machine table, the cutting assembly comprises a support column, the support column is uniformly arranged on the top of the machine table, a horizontal plate is arranged at the top of the support column, support plates are symmetrically arranged at the top of the horizontal plate, an electric cylinder I is arranged on the side, opposite to each other, of the two support plates, a push rod I is fixedly connected to the output end of the electric cylinder I, a sleeve is arranged at the top of the horizontal plate, and a movable block is slidably connected in the sleeve. The filling, heat-sealing, pushing and cutting processes are integrated in the same machine table, the traditional segmented operation mode is abandoned, multiple equipment cooperation and manual transfer are not needed, the overall production efficiency is greatly improved, the errors caused by manual operation are reduced, and the dry powder pollution and metering loss are reduced.

Description

Technical Field

[0001] This invention relates to the field of pharmaceutical packaging production equipment technology, specifically to a fully automated integrated production equipment for single-blister dry powder inhalers. Background Technology

[0002] As a key dosage form for the treatment of respiratory diseases, dry powder inhalers, with their single blister packaging, are increasingly widely used in the pharmaceutical field due to their advantages such as good sealing, precise dosage, and ease of use. With the rapid development of the pharmaceutical industry, the market has placed higher demands on the production efficiency, product quality, and degree of automation of single blister dry powder inhalers.

[0003] Existing production equipment for single-blister dry powder inhalers is mostly segmented, requiring multiple independent machines to complete processes such as filling, heat sealing, and cutting. This not only results in low overall production efficiency but also makes it prone to errors due to manual operation, leading to uneven powder filling and low filling accuracy. Furthermore, segmented transfer can cause powder contamination and metering losses. In addition, traditional blister production equipment requires segmented completion of filling, heat sealing, and cutting operations, resulting in poor synchronization of multiple workstations and large alignment errors. During the feeding process, the film material is prone to deviation, and during cutting, defects such as "uneven edges" and "blister deformation" can easily occur, directly leading to product scrap. Summary of the Invention

[0004] To address the shortcomings of existing technologies, this invention provides a fully automated integrated production equipment for single-blister dry powder inhalers. This solves the problem that existing single-blister dry powder inhaler production equipment often employs a segmented operation structure, requiring multiple independent machines to complete processes such as filling, heat sealing, and cutting. This not only results in low overall production efficiency but also easily introduces errors due to manual operation, leading to uneven powder filling volume and low filling accuracy. Furthermore, segmented transfer can easily cause powder contamination and metering losses. Additionally, traditional blister production equipment requires segmented completion of filling, heat sealing, and cutting operations, resulting in poor synchronization of multiple workstations, large alignment errors, and the potential for film material misalignment during feeding. Defects such as "uneven edges" and "blister deformation" during cutting can directly lead to product scrap.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a fully automatic integrated production equipment for single-bubble dry powder inhalers, comprising a machine base, on the top of which a filling assembly, a heat-sealing assembly, a pushing assembly, and a cutting assembly are sequentially installed. The cutting assembly includes support columns, which are evenly installed on the top of the machine base. A horizontal plate is installed at the top of each support column, and support plates are symmetrically installed on the top of the horizontal plate. An electric cylinder is installed on one side of each of the two support plates, and a push rod is fixedly connected to the output end of the electric cylinder. A sleeve is installed on the top of the horizontal plate, and a movable block is slidably connected inside the sleeve. The bottom end of the push rod is fixedly connected to the top of the movable block. A rod hole is opened in the middle of the horizontal plate, and a lifting rod is slidably connected inside the rod hole. A fixing plate is installed at the bottom of the lifting rod, and a cutting blade is installed at the bottom of the fixing plate. A rod cap is installed at the top of the lifting rod, and a spring is fixedly connected between the bottom of the rod cap and the bottom inner wall of the sleeve.

[0006] By adopting the above technical solutions, the filling, heat sealing, pushing, and cutting processes are integrated into a single machine, eliminating the traditional segmented operation mode. This eliminates the need for multiple machines and manual transfer, greatly improving overall production efficiency while reducing errors caused by manual operation, and minimizing dry powder contamination and metering losses. It also addresses the technical shortcomings of existing equipment, such as poor synchronization of multiple workstations, insufficient benchmarking and filling accuracy, low mold changing efficiency, weak level of intelligence, and inability to simultaneously meet the high-end demands of energy consumption and compliance. This enables high-precision and high-efficiency production of blister packaging, while meeting the compliance and control requirements of high-end industries such as pharmaceuticals, and improving the convenience of equipment operation and maintenance and market adaptability.

[0007] Through the coordinated operation of the cutting and pushing components, fixed-length pushing and cutting can be achieved, ensuring the stability of the cutting and feeding length. At the same time, the rubber strip at the bottom of the push plate can prevent scratching the packaging, and the spring triple-buffered pushing force ensures the smoothness of pushing. During the pushing process, the limiting cooperation of the feeding trough plate can provide a stable track for the continuous and directional movement of the substrate, effectively avoiding the problem of film material deviation in the traditional feeding process, ensuring the accuracy of the substrate position during each process, and effectively solving the problems of "large and small edges" and blister deformation in traditional equipment cutting.

[0008] Preferably, a feeding trough plate is installed on the top of the machine, and a cutting groove is opened at one end of the feeding trough plate near the cutting blade, and the cutting blade is positioned directly above the cutting groove.

[0009] Preferably, the pushing component includes two long legs, the bottoms of the two long legs are symmetrically fixedly connected to the top of the machine, the top of each of the two long legs is fixedly connected to a fixing block, a fixing frame is fixedly connected to one side of the two fixing blocks, a sleeve is fixedly connected inside the fixing frame, a piston is slidably connected inside the sleeve, a spring is fixedly connected between the top of the piston and the inner wall of the top of the sleeve, and a movable rod is fixedly connected to the bottom of the piston.

[0010] Preferably, a slide rail is fixedly connected to one side of the fixed frame, a movable seat is slidably connected to the outer wall of the slide rail, the bottom end of the movable rod is fixedly connected to the top of the movable seat, a fixed seat is installed on one side of the movable seat, a swing rod is rotatably connected inside the fixed seat, a push plate is installed at the bottom end of the swing rod, a rubber strip is fixedly connected to the bottom of the push plate, a vertical block is fixedly connected to the bottom of the movable seat, and a spring is fixedly connected to the side of the vertical block opposite to the swing rod.

[0011] Preferably, a gas supply pipe is fixedly connected to one side of the sleeve, and the end of the gas supply pipe away from the sleeve is fixedly connected to one side of the sleeve. A solenoid valve is installed on the outer wall of the gas supply pipe, and an air inlet pipe is fixedly connected to the other side of the sleeve. A solenoid valve is installed on the outer wall of the air inlet pipe.

[0012] Preferably, the filling assembly includes two short legs, the bottoms of the two short legs are symmetrically fixedly connected to the top of the machine, the tops of the two short legs are fixedly connected to a connecting block, a tank is fixedly connected to one side of the two connecting blocks, and a discharge pipe is fixedly connected to the bottom of the tank.

[0013] Preferably, a motor is installed on the top of the tank, a rotating rod is fixedly connected to the output end of the motor, and a stirring frame is fixedly connected to the outer wall of the rotating rod.

[0014] Preferably, a thin rod is fixedly connected to the bottom end of the rotating rod, a spiral blade is fixedly connected to the outer wall of the thin rod, the spiral blade is disposed inside the discharge pipe, and a feed hopper is fixedly connected to the top of the tank.

[0015] Preferably, the heat sealing assembly includes two grooves, and the top of the machine base is symmetrically provided with grooves. An electric cylinder II is provided in the groove of the machine base. The output ends of the two electric cylinder IIs are fixedly connected to push rod IIs. The top ends of the two push rod IIs are fixedly connected to fixed ears. A thermoplastic roller is rotatably connected to the opposite side of the two fixed ears.

[0016] Preferably, the top of the machine platform is symmetrically fixedly connected with upright plates, and a drum is rotatably connected to one side of the two upright plates facing each other.

[0017] Working principle: The blister substrate is placed in the feeding trough plate, and the roll releases the plastic sealing aluminum paper. When the blister substrate moves to the bottom of the filling component, the motor is started and the rotating rod is driven to rotate. The rotating rod drives the stirring frame to stir the dry powder in the tank to prevent the dry powder from clumping. At the same time, the thin rod at the bottom of the rotating rod drives the spiral blades in the discharge pipe to rotate, so as to realize the quantitative and uniform feeding of dry powder. The dry powder is accurately filled into the blister cavity of the blister substrate through the discharge pipe.

[0018] After the blister powder is filled, the plastic sealing aluminum paper released from the roll covers the surface of the blister substrate. When the blister substrate moves to the heat sealing assembly, the second electric cylinder is activated, pushing the second push rod downward. The second push rod drives the thermoplastic roller downward through the fixed lug. The thermoplastic roller contacts the surface of the plastic sealing aluminum paper, and the rotation of the thermoplastic roller achieves heat sealing of the blister packaging. The second electric cylinder can flexibly adjust the downward pressure height of the thermoplastic roller to adapt to the sealing requirements of blister substrates of different thicknesses and ensure the sealing performance.

[0019] When the sealed blister pack moves to the bottom of the push assembly, start the electric cylinder one, which causes the push rod one to move the movable block down. At this time, the solenoid valve one opens, and the gas in the sleeve flows into the sleeve through the gas supply pipe. The piston in the sleeve moves down under the action of gas pressure. The piston drives the movable rod down, and the movable rod pushes the movable seat down along the slide rail. During the downward movement of the movable seat, the push plate moves towards the cutting blade. With the cooperation of the rubber strip, the sealed blister pack is pushed towards the cutting position. During the downward movement of the movable block, after the movable block moves down to the position of the gas supply pipe port, the solenoid valve one closes and no longer supplies gas into the sleeve.

[0020] With the cooperation of the subsequent operation of the electric cylinder, the moving block continues to move downward. The moving block pushes the rod cap down, the spring is compressed, and the lifting rod drives the cutting blade down. Together with the cutting groove on the feeding trough plate, the blister packaging is cut. Through the coordinated cooperation of the cutting component and the pushing component, fixed-length pushing and cutting can be achieved, ensuring the stability of the cutting and feeding length.

[0021] After cutting, electric cylinder one drives push rod one to move upward, movable block resets, solenoid valve two opens, air inlet pipe supplies air to sleeve, piston inside sleeve moves upward under the elastic force of spring two, driving movable rod and movable seat to reset, preparing for the next push; cutting blade moves upward with lifting rod under the elastic force of spring one, resetting, preparing for the next cutting.

[0022] This invention provides a fully automated integrated production equipment for single-bubble dry powder inhalers. It has the following beneficial effects:

[0023] 1. This invention integrates filling, heat sealing, pushing, and cutting processes into a single machine, abandoning the traditional segmented operation mode. It eliminates the need for multiple machines and manual transfer, greatly improving overall production efficiency while reducing errors caused by manual operation, and minimizing dry powder contamination and metering losses. It solves the technical defects of existing equipment, such as poor synchronization of multiple workstations, insufficient benchmarking and filling accuracy, low mold changing efficiency, weak level of intelligence, and inability to meet high-end demands in terms of energy consumption and compliance. It achieves high-precision and high-efficiency production of blister packaging, while meeting the compliance management requirements of high-end industries such as pharmaceuticals, and improving the convenience of equipment operation and maintenance and market adaptability.

[0024] 2. This invention, through the coordinated operation of the cutting component and the pushing component, can achieve fixed-length pushing and cutting, ensuring the stability of the cutting and feeding length; at the same time, the rubber strip at the bottom of the push plate can prevent scratching the packaging, and the spring triple-buffered pushing force ensures the smoothness of pushing. During the pushing process, the limiting cooperation of the feeding trough plate can provide a stable track for the continuous and directional movement of the substrate, effectively avoiding the problem of film material deviation in the traditional feeding process, ensuring the positional accuracy of the substrate during each process, and effectively solving the problems of "large and small edges" and blister deformation in traditional equipment cutting.

[0025] 3. This invention, by setting up a filling component, utilizes a stirring rack to continuously stir the dry powder inside the tank, which can prevent the dry powder from clumping. At the same time, the thin rod at the bottom of the rotating rod drives the spiral blades inside the discharge pipe to rotate, so that the dry powder inside the tank is accurately filled into the blister cavity of the blister substrate through the discharge pipe, realizing quantitative and uniform feeding of dry powder, ensuring the accuracy and consistency of the dry powder filling amount in the blister cavity, and effectively solving the problem of clogging at the discharge port of traditional filling components. Attached Figure Description

[0026] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0027] Figure 2 This is a schematic diagram of a partial structure of the machine tool of the present invention;

[0028] Figure 3 This is a partial structural diagram of the roll of the present invention;

[0029] Figure 4 This is a schematic diagram of a partial structure of the sleeve of the present invention;

[0030] Figure 5 This is a schematic diagram of a partial structure of the sleeve of the present invention;

[0031] Figure 6 This is a partial structural diagram of the horizontal plate of the present invention;

[0032] Figure 7 This is a schematic diagram of the internal structure of the tank of the present invention;

[0033] Figure 8 This is a partial structural diagram of the thermoplastic roller of the present invention.

[0034] The components include: 1. Machine base; 2. Cutting assembly; 201. Support column; 202. Horizontal plate; 203. Support plate; 204. Electric cylinder one; 205. Push rod one; 206. Sleeve; 207. Movable block; 208. Lifting rod; 209. Spring one; 210. Rod cap; 211. Fixing plate; 212. Cutting blade; 3. Pushing assembly; 301. Long support leg; 302. Fixing block; 303. Fixing frame; 304. Sleeve; 305. Piston; 306. Spring two; 307. Movable rod; 308. Slide rail; 309. Movable seat; 310. Fixing seat; 311. Swing rod; 312. Push plate; 313. 314. Rubber strip; 315. Vertical block; 316. Spring three; 317. Gas transmission pipe; 318. Solenoid valve one; 319. Air inlet pipe; 310. Solenoid valve two; 4. Filling assembly; 401. Short support leg; 402. Connecting block; 403. Tank body; 404. Discharge pipe; 405. Motor; 406. Rotating rod; 407. Mixing rack; 408. Thin rod; 409. Spiral blade; 410. Feed hopper; 5. Heat sealing assembly; 501. Groove; 502. Electric cylinder two; 503. Push rod two; 504. Fixing ear; 505. Thermoplastic roller; 6. Feeding trough plate; 7. Cutting groove; 8. Vertical plate; 9. Roller. Detailed Implementation

[0035] The technical solution of the present invention will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0036] Please see the appendix Figure 1 - Appendix Figure 8This invention provides a fully automatic integrated production equipment for single-bubble dry powder inhalers, including a machine base 1. A filling assembly 4, a heat-sealing assembly 5, a pushing assembly 3, and a cutting assembly 2 are sequentially installed on the top of the machine base 1. The cutting assembly 2 includes support columns 201. Support columns 201 are evenly installed on the top of the machine base 1. A horizontal plate 202 is installed at the top of each support column 201. Support plates 203 are symmetrically installed on the top of each horizontal plate 202. An electric cylinder 204 is installed on one side of each of the two support plates 203 facing each other. A push rod 205 is fixedly connected to the output end of the electric cylinder 204. A sleeve 206 is installed on the top of the plate 202. A movable block 207 is slidably connected inside the sleeve 206. The bottom end of the push rod 205 is fixedly connected to the top of the movable block 207. A rod hole is opened in the middle of the horizontal plate 202. A lifting rod 208 is slidably connected inside the rod hole of the horizontal plate 202. A fixing plate 211 is installed at the bottom of the lifting rod 208. A cutting blade 212 is installed at the bottom of the fixing plate 211. A rod cap 210 is installed at the top of the lifting rod 208. A spring 209 is fixedly connected between the bottom of the rod cap 210 and the bottom inner wall of the sleeve 206.

[0037] Specifically, when the sealed blister pack moves to below the push assembly 3, the electric cylinder 204 is activated, causing the push rod 205 to move the movable block 207 downward. At this time, the solenoid valve 317 opens, and the gas in the sleeve 206 flows into the sleeve 304 through the gas supply pipe 316. The piston 305 in the sleeve 304 moves downward under the action of air pressure. The piston 305 moves the movable rod 307 downward, and the movable rod 307 pushes the movable seat 309 downward along the slide rail 308. During the downward movement of the movable seat 309, the push plate 312 moves towards the cutting blade 212. With the cooperation of the rubber strip 313, the sealed blister pack is pushed towards the cutting position. During the downward movement of the movable block 207, after the movable block 207 moves to the position of the gas supply pipe 316 port, the solenoid valve 317 closes and no longer supplies air into the sleeve 304.

[0038] With the cooperation of the subsequent electric cylinder 204, the movable block 207 is pushed to continue moving downward. The movable block 207 pushes the rod cap 210 to move down, the spring 209 is compressed, and the lifting rod 208 drives the cutting blade 212 to move down. Together with the cutting groove 7 on the feeding trough plate 6, the blister packaging is cut. Through the coordinated cooperation of the cutting component 2 and the pushing component 3, fixed-length pushing and cutting can be achieved, ensuring the stability of the cutting and feeding length.

[0039] After cutting, electric cylinder 204 drives push rod 205 to move upward, movable block 207 resets, solenoid valve 319 opens, air inlet pipe 318 supplies air to sleeve 206, piston 305 inside sleeve 304 moves upward under the elastic force of spring 306, driving movable rod 307 and movable seat 309 to reset, preparing for the next push; cutting blade 212 moves upward with lifting rod 208 under the elastic force of spring 209, resetting, preparing for the next cutting;

[0040] By integrating filling, heat sealing, pushing, and cutting processes into a single machine, the traditional segmented operation mode is abandoned. This eliminates the need for multiple machines and manual transfer, greatly improving overall production efficiency while reducing errors caused by manual operation, and minimizing dry powder contamination and metering losses. It also addresses the technical shortcomings of existing equipment, such as poor synchronization of multiple workstations, insufficient benchmarking and filling accuracy, low mold changing efficiency, weak level of intelligence, and inability to meet the demands of high-end industries in terms of energy consumption and compliance. This enables high-precision and high-efficiency production of blister packaging, while meeting the compliance and control requirements of high-end industries such as pharmaceuticals, and improving the convenience of equipment operation and maintenance and market adaptability.

[0041] By setting up the filling component 4, the dry powder in the tank 403 is continuously stirred by the stirring rack 407, which can prevent the dry powder from clumping. At the same time, the thin rod 408 at the bottom of the rotating rod 406 drives the spiral blade 409 in the discharge pipe 404 to rotate, so that the dry powder in the tank 403 is accurately filled into the blister cavity of the blister substrate through the discharge pipe 404, realizing the quantitative and uniform feeding of dry powder, ensuring the accuracy and consistency of the dry powder filling amount in the blister cavity, and effectively solving the problem of clogging at the discharge port of the traditional filling component 4.

[0042] Please see the appendix Figure 1 - Appendix Figure 3 Appendix Figure 8 The top of the machine base 1 is equipped with a feeding trough plate 6. A cutting groove 7 is opened at one end of the feeding trough plate 6 near the cutting blade 212. The cutting blade 212 is located directly above the cutting groove 7.

[0043] Specifically, by setting the feeding trough plate 6, a stable track can be provided for the continuous and directional movement of the substrate, effectively avoiding the problem of film material deviation during traditional feeding process, and ensuring the positional accuracy of the substrate during each process.

[0044] A cutting groove 7 is provided at the end of the feeding trough plate 6 near the cutting blade 212, and the cutting blade 212 is precisely positioned above the cutting groove 7. This structural design allows the cutting blade 212 to be embedded in the cutting groove 7 when it moves down to cut, which not only enables the cutting blade 212 to accurately cut the blister substrate and ensures that the cut edges are neat, thus completely solving the problem of "large and small edges" that is easy to occur in traditional cutting, but also avoids the cutting blade 212 from directly contacting the working surface of the machine base 1 or the feeding trough plate 6, effectively preventing blade wear and chipping, and extending the service life of the cutting blade 212.

[0045] Please see the appendix Figure 1 - Appendix Figure 5 The push assembly 3 includes two long legs 301, the bottoms of which are symmetrically fixed to the top of the machine base 1. Each long leg 301 has a fixed block 302 fixed to its top. A fixed frame 303 is fixedly connected to the opposite side of each fixed block 302. A sleeve 304 is fixedly connected inside the fixed frame 303. A piston 305 is slidably connected inside the sleeve 304. A spring 306 is fixedly connected between the top of the piston 305 and the inner wall of the top of the sleeve 304. A movable rod 307 is fixedly connected to the bottom of the piston 305. A slide rail 308 is fixedly connected to one side of the fixed frame 303. A movable seat 309 is slidably connected to the outer wall of the slide rail 308. The bottom end of the movable rod 307 is fixedly connected to the movable seat 309. At the top of 9, a fixed seat 310 is installed on one side of the movable seat 309. A rocker arm 311 is rotatably connected inside the fixed seat 310. A push plate 312 is installed at the bottom of the rocker arm 311. A rubber strip 313 is fixedly connected to the bottom of the push plate 312. A vertical block 314 is fixedly connected to the bottom of the movable seat 309. A spring 315 is fixedly connected to the side of the vertical block 314 opposite to the rocker arm 311. An air supply pipe 316 is fixedly connected to one side of the sleeve 304. The end of the air supply pipe 316 away from the sleeve 304 is fixedly connected to one side of the sleeve 206. A solenoid valve 317 is installed on the outer wall of the air supply pipe 316. An air inlet pipe 318 is fixedly connected to the other side of the sleeve 206. A solenoid valve 319 is installed on the outer wall of the air inlet pipe 318.

[0046] Specifically, when the sealed blister pack moves to below the push assembly 3, the electric cylinder 204 is activated, causing the push rod 205 to move the movable block 207 downward. At this time, the solenoid valve 317 opens, and the gas in the sleeve 206 flows into the sleeve 304 through the gas supply pipe 316. The piston 305 in the sleeve 304 moves downward under the action of air pressure. The piston 305 moves the movable rod 307 downward, and the movable rod 307 pushes the movable seat 309 downward along the slide rail 308. During the downward movement of the movable seat 309, the push plate 312 moves towards the cutting blade 212. With the cooperation of the rubber strip 313, the sealed blister pack is pushed towards the cutting position. During the downward movement of the movable block 207, after the movable block 207 moves to the position of the gas supply pipe 316 port, the solenoid valve 317 closes and no longer supplies air into the sleeve 304.

[0047] With the assistance of the electric cylinder 204, the movable block 207 continues to move downwards. The movable block 207 pushes the rod cap 210 downwards, compressing the spring 209. The lifting rod 208 drives the cutting blade 212 downwards, working with the cutting groove 7 on the feeding trough plate 6 to complete the cutting of the blister packaging. Through the coordinated operation of the cutting component 2 and the pushing component 3, fixed-length pushing and cutting can be achieved, ensuring the stability of the cutting and feeding length. At the same time, the rubber strip 313 at the bottom of the push plate 312 can prevent scratching the packaging, and the spring 315 buffers the pushing force to ensure the smoothness of the pushing. During the pushing process, the limiting cooperation of the feeding trough plate 6 can provide a stable track for the continuous and directional movement of the substrate, effectively avoiding the problem of film material deviation in the traditional feeding process, ensuring the positional accuracy of the substrate during each process, and effectively solving the problems of "large and small edges" and blister deformation in traditional equipment cutting.

[0048] Please see the appendix Figure 1 - Appendix Figure 3 Appendix Figure 7 - Appendix Figure 8 The filling assembly 4 includes two short legs 401. The bottoms of the two short legs 401 are symmetrically fixed to the top of the machine base 1. A connecting block 402 is fixedly connected to the top of each of the two short legs 401. A tank body 403 is fixedly connected to the opposite side of the two connecting blocks 402. A discharge pipe 404 is fixedly connected to the bottom of the tank body 403. A motor 405 is installed on the top of the tank body 403. A rotating rod 406 is fixedly connected to the output end of the motor 405. A stirring frame 407 is fixedly connected to the outer wall of the rotating rod 406. A thin rod 408 is fixedly connected to the bottom end of the rotating rod 406. A spiral blade 409 is fixedly connected to the outer wall of the thin rod 408. The spiral blade 409 is disposed inside the discharge pipe 404. A feed hopper 410 is fixedly connected to the top of the tank body 403.

[0049] Specifically, when the blister substrate moves to the bottom of the filling assembly 4, the motor 405 is started, driving the rotating rod 406 to rotate. The rotating rod 406 drives the stirring frame 407 to stir the dry powder in the tank 403, which can prevent the dry powder from clumping. At the same time, the thin rod 408 at the bottom of the rotating rod 406 drives the spiral blades 409 in the discharge pipe 404 to rotate, so that the dry powder in the tank 403 is accurately filled into the blister cavity of the blister substrate through the discharge pipe 404, realizing the quantitative and uniform feeding of dry powder, ensuring the accuracy and consistency of the dry powder filling amount in the blister cavity, and effectively solving the problem of clogging at the discharge port of the traditional filling assembly 4.

[0050] Please see the appendix Figure 1 - Appendix Figure 3 Appendix Figure 8 The heat sealing assembly 5 includes two grooves 501. The top of the machine base 1 is symmetrically provided with grooves 501. Electric cylinder 2 502 is provided in the groove 501 of the machine base 1. The output ends of the two electric cylinders 2 502 are fixedly connected with push rod 2 503. The top ends of the two push rods 2 503 are fixedly connected with fixing ears 504. Thermoplastic roller 505 is rotatably connected to the opposite side of the two fixing ears 504.

[0051] Specifically, the filled blister powder is released by the roll 9 and covers the surface of the blister substrate with plastic sealing aluminum paper. When the blister substrate moves to the heat sealing assembly 5, the electric cylinder 502 is activated to push the push rod 503 down. The push rod 503 drives the thermoplastic roller 505 down through the fixed ear 504. The thermoplastic roller 505 contacts the surface of the plastic sealing aluminum paper, and the blister packaging is heat-sealed by the rotation of the thermoplastic roller 505.

[0052] The pressure height of the thermoplastic roller 505 can be flexibly adjusted by the electric cylinder 502 to adapt to the sealing requirements of blister substrates of different thicknesses and ensure sealing performance.

[0053] Please see the appendix Figure 1 - Appendix Figure 3 Appendix Figure 8 The top of the machine base 1 is symmetrically fixedly connected with vertical plates 8, and the opposite side of the two vertical plates 8 is rotatably connected with a drum 9.

[0054] Specifically, two upright plates 8 are symmetrically fixed on the top of the machine base 1, providing a symmetrical and sturdy double-sided support structure for the roll 9, avoiding tilting and shaking problems caused by force on one side of the roll 9, making the rotation of the roll 9 more stable, ensuring that there is no jamming or pulling during the unwinding process of the plastic sealing aluminum paper, and ensuring the continuity of packaging film material delivery.

[0055] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A fully automatic integrated production equipment for single-bubble dry powder inhalers, comprising a machine base (1), characterized in that: The top of the machine (1) is sequentially equipped with a filling assembly (4), a heat sealing assembly (5), a pushing assembly (3), and a cutting assembly (2). The cutting assembly (2) includes a support column (201). The support columns (201) are evenly installed on the top of the machine (1). A horizontal plate (202) is installed at the top of the support column (201). Support plates (203) are symmetrically installed on the top of the horizontal plate (202). An electric cylinder (204) is installed on one side opposite to the two support plates (203). A push rod (205) is fixedly connected to the output end of the electric cylinder (204). A sleeve (206) is installed on the top of the horizontal plate (202). The sleeve (206) is slidably connected to a movable block (207). The bottom end of the push rod (205) is fixedly connected to the top of the movable block (207). A rod hole is opened in the middle of the horizontal plate (202). A lifting rod (208) is slidably connected in the rod hole of the horizontal plate (202). A fixing plate (211) is installed at the bottom end of the lifting rod (208). A cutting blade (212) is installed at the bottom of the fixing plate (211). A rod cap (210) is installed at the top end of the lifting rod (208). A spring (209) is fixedly connected between the bottom of the rod cap (210) and the bottom inner wall of the sleeve (206).

2. The fully automatic integrated production equipment for a single-bubble dry powder inhaler according to claim 1, characterized in that: The top of the machine base (1) is equipped with a feeding trough plate (6), and a cutting groove (7) is provided at one end of the feeding trough plate (6) near the cutting blade (212). The cutting blade (212) is located directly above the cutting groove (7).

3. The fully automatic integrated production equipment for a single-bubble dry powder inhaler according to claim 1, characterized in that: The pushing component (3) includes two long legs (301), the bottoms of the two long legs (301) are symmetrically fixed to the top of the machine (1), the tops of the two long legs (301) are fixedly connected to a fixing block (302), a fixing frame (303) is fixedly connected to the opposite side of the two fixing blocks (302), a sleeve (304) is fixedly connected inside the fixing frame (303), a piston (305) is slidably connected inside the sleeve (304), a spring (306) is fixedly connected between the top of the piston (305) and the top inner wall of the sleeve (304), and a movable rod (307) is fixedly connected to the bottom of the piston (305).

4. The fully automatic integrated production equipment for a single-bubble dry powder inhaler according to claim 3, characterized in that: A slide rail (308) is fixedly connected to one side of the fixed frame (303). A movable seat (309) is slidably connected to the outer wall of the slide rail (308). The bottom end of the movable rod (307) is fixedly connected to the top of the movable seat (309). A fixed seat (310) is installed on one side of the movable seat (309). A swing rod (311) is rotatably connected inside the fixed seat (310). A push plate (312) is installed at the bottom end of the swing rod (311). A rubber strip (313) is fixedly connected to the bottom of the push plate (312). A vertical block (314) is fixedly connected to the bottom of the movable seat (309). A spring (315) is fixedly connected to the side opposite to the vertical block (314) and the swing rod (311).

5. The fully automatic integrated production equipment for a single-bubble dry powder inhaler according to claim 3, characterized in that: A gas delivery pipe (316) is fixedly connected to one side of the sleeve (304). The end of the gas delivery pipe (316) away from the sleeve (304) is fixedly connected to one side of the sleeve (206). A solenoid valve one (317) is installed on the outer wall of the gas delivery pipe (316). An air inlet pipe (318) is fixedly connected to the other side of the sleeve (206). A solenoid valve two (319) is installed on the outer wall of the air inlet pipe (318).

6. The fully automatic integrated production equipment for a single-bubble dry powder inhaler according to claim 1, characterized in that: The filling assembly (4) includes two short legs (401), the bottoms of the two short legs (401) are symmetrically fixed to the top of the machine base (1), the tops of the two short legs (401) are fixedly connected to connecting blocks (402), the opposite sides of the two connecting blocks (402) are fixedly connected to a tank body (403), and the bottom of the tank body (403) is fixedly connected to a discharge pipe (404).

7. The fully automatic integrated production equipment for a single-bubble dry powder inhaler according to claim 6, characterized in that: A motor (405) is installed on the top of the tank (403), and a rotating rod (406) is fixedly connected to the output end of the motor (405). A stirring rack (407) is fixedly connected to the outer wall of the rotating rod (406).

8. The fully automatic integrated production equipment for a single-bubble dry powder inhaler according to claim 7, characterized in that: The bottom end of the rotating rod (406) is fixedly connected to a thin rod (408), and the outer wall of the thin rod (408) is fixedly connected to a spiral blade (409). The spiral blade (409) is disposed inside the discharge pipe (404), and the top of the tank (403) is fixedly connected to a feed hopper (410).

9. The fully automatic integrated production equipment for a single-bubble dry powder inhaler according to claim 1, characterized in that: The heat sealing assembly (5) includes two grooves (501). The top of the machine base (1) is symmetrically provided with grooves (501). Electric cylinders (502) are provided in the grooves (501) of the machine base (1). Push rods (503) are fixedly connected to the output ends of the two electric cylinders (502). Fixed ears (504) are fixedly connected to the top ends of the two push rods (503). Thermoplastic rollers (505) are rotatably connected to the opposite side of the two fixed ears (504).

10. The fully automatic integrated production equipment for a single-bubble dry powder inhaler according to claim 1, characterized in that: The top of the machine base (1) is symmetrically fixedly connected with vertical plates (8), and a drum (9) is rotatably connected to one side of the two vertical plates (8) opposite to each other.

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