A method for detecting components of a traditional Chinese medicine composition for treating abnormal uterine bleeding
By using UHPLC-MS technology to detect the components of traditional Chinese medicine compositions, the problem of incomplete detection in existing technologies has been solved, enabling systematic identification of the components of traditional Chinese medicine compositions and improving the reliability of quality control and clinical application.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- HEBEI PING AN HEALTH GRP CO LTD
- Filing Date
- 2026-04-30
- Publication Date
- 2026-06-19
AI Technical Summary
Existing technologies cannot systematically and comprehensively detect the chemical composition of traditional Chinese medicine compositions for treating abnormal uterine bleeding, making it difficult to guarantee their process stability, batch consistency, and clinical efficacy consistency, and thus failing to meet the requirements of modern traditional Chinese medicine quality evaluation and registration application.
A rapid and sensitive detection method was established using ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS) combined with gradient elution and positive and negative ion modes. The test solution was prepared by ultrasonic extraction and filtration, and the qualitative identification of various compounds was achieved by combining database and software analysis.
It enables systematic and accurate detection of components in traditional Chinese medicine compositions, supports pharmacokinetic and pharmacodynamic material basis research, lays a theoretical foundation for clinical application, and improves quality control and safety.
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