Bifidobacterium longum immune-enhancing composition for increasing igA level

By scientifically combining active probiotics and heat-inactivated biogenerants, along with compound excipients and advanced preparation processes, the problems of easy inactivation and insufficient stability of existing products in the acidic environment of the stomach have been solved, achieving highly efficient immune enhancement effects and wide application.

CN122398869APending Publication Date: 2026-07-17UWORTH (HAINAN) TECHNOLOGY CONSULTING CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
UWORTH (HAINAN) TECHNOLOGY CONSULTING CO LTD
Filing Date
2026-05-15
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing probiotic products for enhancing immunity lack scientifically formulated strains and postbiotic pairings, resulting in poor immune regulation effects. Probiotics are easily inactivated in the acidic environment of the stomach, leading to insufficient product stability and palatability. Traditional preparation processes lack standardization, affecting practical application effects.

Method used

By employing a scientific ratio of active probiotics and heat-inactivated probiotics, and through the combination of compound excipients and a double-layer encapsulation structure, along with anaerobic and aerobic fermentation, low-temperature centrifugation, precise heat inactivation, and vacuum freeze-drying processes, a Bifidobacterium immune-enhancing composition that improves IgA levels was prepared.

Benefits of technology

It achieves the synergistic effect of probiotics and postbiotics, enhances the body's mucosal immune IgA level, and ensures the stability and palatability of the composition in the gastric acid environment, making it suitable for the food and health food industries.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明公开了一种提升IgA水平的两歧双歧杆菌免疫增强组合物,涉及微生态制剂技术领域,该组合物以重量份计,由活性益生菌组分、灭活后生元组分和辅料组分构成;所述活性益生菌组分为两歧双歧杆菌活菌冻干粉、长双歧杆菌活菌冻干粉、鼠李糖乳杆菌活菌冻干粉,其中两歧双歧杆菌活菌冻干粉为10~30份,长双歧杆菌活菌冻干粉为10~30份,鼠李糖乳杆菌活菌冻干粉为10~30份,活性益生菌组分总重量份为30~90份,总活菌数为1×109CFU / g~1×1011 CFU / g;本发明通过复配多种活性益生菌与热灭活后生元形成协同体系,提升IgA水平,双层包埋、科学复配辅料提升生物利用度等;标准化工艺保障活性,从双维度提升肠道健康与免疫,适用场景广。
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