Deep learning based coronary cta automatic segmentation method

By using a deep learning framework based on nnU-Net, automatic segmentation of coronary CTA images was achieved, solving the problems of high workload and inaccurate segmentation caused by manual image reading. This improved the accuracy and consistency of segmentation, reduced the complexity of model training and deployment, and met the needs of rapid clinical application.

CN122415646APending Publication Date: 2026-07-17THE FIRST AFFILIATED HOSPITAL OF ANHUI MEDICAL UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
THE FIRST AFFILIATED HOSPITAL OF ANHUI MEDICAL UNIV
Filing Date
2026-04-22
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

In existing coronary CTA technology, manual image segmentation and identification are labor-intensive and experience-dependent. Furthermore, existing methods are difficult to accurately segment vascular branches and small vessels, resulting in poor consistency and accuracy of results. Deep learning models are complex to train and difficult to deploy.

Method used

An automatic coronary artery CTA segmentation method based on the nnU-Net adaptive deep learning framework is adopted, including data preprocessing, model building and training, prediction and post-processing. The segmentation results are optimized by using the 3DU-Net architecture, a hybrid loss function and five-fold cross-validation, combined with morphological operations.

Benefits of technology

It enables automatic segmentation of coronary CTA images, reducing the workload of doctors, improving the accuracy and consistency of segmentation, reducing reliance on experience, enhancing the model's generalization ability and deployment efficiency, and meeting the needs of rapid clinical application.

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Abstract

本发明公开了基于深度学习的冠脉CTA自动分割方法,属于医学影像处理与人工智能交叉领域,包括以下步骤:获取冠脉CTA图像数据集;对冠脉CTA图像进行统一分辨率重采样、归一化与空间配准,基于nnU‑Net自适应深度学习框架构建分割模型,并采用五折交叉验证策略训练模型,其中模型采用3DU‑Net架构,使用训练好的模型对输入的冠脉CTA图像进行分割,生成冠脉分割mask;对冠脉分割mask进行形态学操作;将分割结果集成到临床决策辅助系统;本方法通过构建基于深度学习的自动分割模型,实现了冠脉CTA图像的自动分割,无需人工逐一阅片进行分段与识别,减轻了临床医生的工作负担,同时降低了对人工经验的依赖程度,使分割过程更加客观、标准化。
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