A compound probiotic for preparing and preventing ketosis of dairy cows and application thereof

By using compound probiotics to optimize the rumen microbiota structure of dairy cows and increase the content of VFAs and propionic acid, the problem of prevention and treatment of ketosis in dairy cows has been solved. This has resulted in improved energy metabolism and reduced blood indicators, avoiding the inconvenience of traditional treatments and the risks of hormone drugs.

CN122542425BActive Publication Date: 2026-09-08JILIN UNIVERSITY
2 Cites 0 Cited by

Patent Information

Application Number
CN202611039482.0
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2026-07-14
Publication Date
2026-09-08
Estimated Expiration
2046-07-14

AI Technical Summary

Technical Problem

Existing technologies are insufficient to effectively prevent and treat ketosis in dairy cows, leading to decreased production performance, reduced milk quality, and increased risk of infectious diseases. Furthermore, traditional treatment methods are inconvenient to implement and pose a risk of metabolic interference with hormonal drugs.

Method used

A compound probiotic consisting of Weissella L5, Pediococcus pentosus G41, and Lactobacillus paracasei S1 is administered orally to the rumen of dairy cows to optimize the rumen microbiota structure, increase the content of VFAs and propionic acid in rumen fluid, reduce the acetic acid/propionic acid ratio, and improve energy metabolism.

Benefits of technology

It significantly increases the content of VFAs and propionic acid in the rumen fluid of dairy cows, reduces the levels of NEFA, BHBA, ALT and AST in the blood, improves energy metabolism, reduces the burden on the liver, and achieves effective prevention and treatment of ketosis in dairy cows, avoiding the inconvenience of traditional treatments and the side effects of hormone drugs.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

The application provides a kind of for preparing the complex probiotics for preventing and treating ketosis of dairy cow and application thereof, belongs to the field of microbial technology, Weissella L5, Pediococcus pentosaceus G41 and Paracasei S1 are compounded as active ingredients to form. Through the mutual synergistic effect of three kinds of probiotics, the energy metabolism state of ketosis dairy cow is significantly improved, which is specifically manifested as follows: the total volatile fatty acid and propionic acid content in rumen fluid is increased, the non-esterified fatty acid, beta-hydroxybutyric acid, glutamic-pyruvic transaminase and glutamic-oxalacetic transaminase level in blood is reduced, and the blood glucose level is increased. By supplementing the complex probiotics into the rumen of dairy cow, the rumen flora structure is optimized, the production of glycolysis precursor substances such as propionic acid is increased, the energy metabolism state of dairy cow is improved, the energy negative balance is relieved, and finally the effective prevention and treatment of ketosis of dairy cow is realized.
Need to check novelty before this filing date? Find Prior Art