A compound traditional Chinese medicine composition for treating chronic atrophic gastritis and a preparation method thereof

This compound Chinese medicine composition, consisting of cinnamon twig, codonopsis, and other herbs, employs the "promoting yang and dispelling turbidity" treatment method. It solves the problem of spleen deficiency and yang stagnation in the treatment of chronic atrophic gastritis by traditional Chinese medicine, achieving the effects of reversing gastric mucosal atrophy and intestinal metaplasia, and blocking the transformation of gastric cancer. It is suitable for primary healthcare institutions.

CN122681963APending Publication Date: 2026-09-04GUANGDONG SECOND TRADITIONAL CHINESE MEDICINE HOSPITAL (GUANGDONG PROVINCE ENG TECH RES INST OF TCM)
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Patent Information

Application Number
CN202611155593.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-07-31
Publication Date
2026-09-04

AI Technical Summary

Technical Problem

Current TCM treatments for chronic atrophic gastritis (CAG) lack effective methods targeting the pathogenesis of "spleen deficiency and yang stagnation," making it difficult to reverse intestinal metaplasia and block the transformation process of gastric cancer. Furthermore, traditional prescriptions are prone to damaging the spleen and stomach yang or causing imbalances in cold and heat.

Method used

A compound traditional Chinese medicine composition is provided, comprising cinnamon twig, codonopsis, poria, immature bitter orange, ginger-processed pinellia, evodia, ophiopogon, dandelion, and prepared licorice. It adopts the treatment method of "promoting yang and resolving turbidity". Cinnamon twig warms and unblocks the meridians, poria promotes diuresis and eliminates dampness, immature bitter orange breaks up qi and eliminates stagnation, evodia opens up and descends with its pungent and bitter properties, and ophiopogon nourishes yin and protects the stomach, thereby restraining the warming and dryness, so as to achieve both symptomatic and root-cause treatment.

Benefits of technology

It significantly improves the clinical symptoms of patients with spleen deficiency and yang stagnation type CAG, reverses gastric mucosal atrophy and intestinal metaplasia, blocks "inflammation-cancer transformation", has high safety and few side effects, and is suitable for promotion in primary medical institutions.

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Abstract

The application discloses a compound traditional Chinese medicine composition for treating chronic atrophic gastritis and a preparation method thereof, and particularly relates to the technical field of traditional Chinese medicine.The composition comprises guizhi, dangshen, fuling, jujube, Jiangbanxia, wuzhuyu, maidong, dandelion and zhigancao.The application reconstructs monarch, minister and assistant, and constructs three core synergistic drug pairs: the guizhi, the dangshen and the zhigancao are used as monarch drugs, the guizhi is used again to stimulate meridian qi and warm and pass yang qi;the guizhi and the fuling practice the purpose of 'passing yang is not in warming, but in benefiting urination', and help to pass yang and strengthen the function of resolving turbidity through water benefitting and dampness eliminating;the guizhi and the jujube comply with the principle of 'the stomach is supplemented by passing', one warms and passes chest yang, one moves qi and eliminates stagnation, and the effect of passing yang and moving qi is achieved;the wuzhuyu and the dandelion skillfully use the method of 'acrid opening and bitter descending', balance cold and heat, clear and resolve heat toxin caused by yang depression, avoid bitter cold damaging yang or acrid heat assisting fire, realize the balance of 'clearing without damaging yang', and the maidong is used to nourish yin and protect the stomach and restrict warm dryness, the whole prescription is well matched, and the composition can treat both symptoms and root causes.
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