Fish skin bleaching solution and its use

CN122912184APending Publication Date: 2026-10-16BEIJING MEICUI BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202611044732.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-07-14
Publication Date
2026-10-16

AI Technical Summary

Technical Problem

[0003]然而,传统的ECM来源主要依赖于哺乳动物皮肤或肌腱,与人类亲缘较近,其使用过程中可能受某些宗教文化限制且有传染相关人畜共患疾病(如疯牛病、蓝耳病等)的风险,逐渐难以满足日益增长的临床需求

Benefits of technology

[0071]This invention, without significantly affecting the properties of the extracellular matrix, adds decolorization and virus inactivation steps suitable for fish skin tissue to reduce the risk of immune rejection and inflammation after implantation, and cuts off the route of viral transmission to the user via the product, thus meeting the requirements for the safety and effectiveness of implantable medical devices. The resulting material has good biocompatibility, biodegradability, and tissue regeneration promotion capabilities, and can be processed into sponges, powders, gels, etc., with wide applications in hemostasis, wound repair, and tissue engineering. This invention features a simple, safe, environmentally friendly, and low-cost process, and has broad prospects for clinical translation.

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Abstract

The application belongs to the technical field of biological materials, and relates to a fish skin bleaching solution and application thereof.The fish skin bleaching solution comprises persulfate, sodium metasilicate, a bleaching accelerator and a solvent.In view of the problem of deep color of fish skin, the fish skin bleaching solution is provided, the components cooperate with each other and synergistically act, the dosage of the persulfate is reduced under the premise of ensuring the decolorization effect, the fish skin bleaching solution is safer and easier to remove.The decellularized extracellular matrix prepared by using the fish skin bleaching solution has good biocompatibility and can be widely applied to the fields of medical instruments, medical materials, medical and aesthetic injection filling materials and the like.
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