Film scratching instrument

Abstract

The utility model relates to a film scratching instrument which comprises a film scratching platform which comprises a tray and a first movement assembly connected with the tray, the tray bears paper with a film to be scratched, and the first movement assembly controls the tray to move in the horizontal direction; the liquid adding mechanism comprises a liquid adding needle and a second movement assembly, the liquid adding needle is connected to the second movement assembly and used for allowing the reagent to pass through and sliding on the paper, and the second movement assembly controls the liquid adding needle to move in the vertical direction and the vertical direction; the liquid injection mechanism comprises a microsyringe and a micro-motion mechanism, one end of the microsyringe is communicated with the liquid adding needle, the other end of the microsyringe is connected with the micro-motion mechanism, and the microsyringe is used for containing a reagent; the micro-motion mechanism is used for controlling the microsyringe to suck or release a reagent; and the control box is used for controlling the first motion assembly, the second motion assembly and / or the micro-motion mechanism to act. The film scratching instrument disclosed by the utility model is controlled by the micro-motion mechanism and is matched with the microsyringe for use, so that trace liquid adding can be realized, and the film scratching lines are uniform.

Description

Technical Field

[0001] The utility model relates to the technical field of medical equipment, in particular to a membrane scratching instrument. Background Art

[0002] The streaking instrument is an important instrument currently used to make test kits. Generally speaking, during the process of making test kits, the streaking instrument streaks the test reagents on paper. However, the current streaking instrument cannot achieve uniform micro-amount liquid addition during the process of streaking the reagents onto paper, resulting in intermittent liquid addition and discontinuous liquid discharge defects. It is also difficult to control the thickness of the liquid addition line, or the structure for achieving micro-amount liquid addition is complex, resulting in high product costs. Utility Model Content

[0003] In view of the technical problems existing in the prior art, the utility model proposes a film stripping instrument, comprising: a film stripping platform, which comprises a tray and a first motion component connected to the tray, the tray carries the paper to be stripped, and the first motion component controls the movement of the tray in the horizontal direction; a liquid adding mechanism, which comprises a liquid adding needle and a second motion component, the liquid adding needle is connected to the second motion component and is used to accommodate the reagent to pass through and stripe on the paper, and the second motion component controls the movement of the liquid adding needle in the vertical direction and the vertical direction; a liquid injection mechanism, which comprises a micro-injector and a micro-motion mechanism, one end of the micro-injector is connected to the liquid adding needle, and the other end is connected to the micro-motion mechanism and is used to accommodate the reagent; the micro-motion mechanism is used to control the micro-injector to absorb or release the reagent; and a control box, which is used to control the action of the first motion component, the second motion component and / or the micro-motion mechanism; wherein the micro-motion mechanism comprises a reduction motor and a ball screw, and the nut on the ball screw is connected to the micro-injector.

[0004] In the film scratching instrument as described above, the lead of the ball screw is not greater than 1 mm.

[0005] As described above, the film scratching instrument, the micro-injector includes a cylinder and a piston, the cylinder includes a cylindrical cavity, which is used to accommodate reagents, the cylinder includes an opening at one end away from the piston, the opening connects the cavity and the liquid adding needle, and is used to accommodate the reagent to enter and exit the cavity; the piston is arranged in the cavity and is connected to the micro-motion mechanism to reciprocate in the cavity.

[0006] In the film scratching instrument as described above, the diameter of the cavity is not greater than 2.3 mm.

[0007] In the membrane scratching instrument as described above, the outer diameter of the liquid adding needle is less than 0.5 mm, and the inner diameter is not greater than 0.2 mm.

[0008] The film stripping instrument as described above further comprises: a solenoid valve, which comprises one or more inlets and one or more outlets, the micro-injector and the liquid adding needle are connected to the outlets, and the inlet is connected to one or more reagent bottles containing reagents.

[0009] The film scribing instrument as described above further comprises: a reagent rack for carrying the reagent bottles.

[0010] The film scratching instrument as described above further comprises a bracket connected to the second motion component, and the liquid adding needle is arranged on the bracket.

[0011] As described above, the membrane scratcher comprises a connecting hole on the bracket, which is used for connecting the bracket to the liquid adding needle.

[0012] As described above, the film scratching instrument, the connection hole is in the shape of an elongated strip and includes a plurality of connection positions thereon.

[0013] The film-scratching instrument of the present application is controlled by a micro-motion mechanism and can achieve micro-liquid addition when used in conjunction with a micro-injector, and the lines of the film-scratching are uniform. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Below, the preferred embodiments of the present invention will be further described in detail with reference to the accompanying drawings, wherein:

[0015] Figure 1 A schematic diagram of a film scratching instrument according to an embodiment of the present application;

[0016] Figure 2 is a schematic diagram of a liquid adding mechanism according to an embodiment of the present application; and

[0017] Figure 3 Schematic diagram of a liquid pumping mechanism according to one embodiment of the present application. DETAILED DESCRIPTION

[0018] In order to make the purpose, technical solution and advantages of the embodiment of the utility model clearer, the technical solution in the embodiment of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiment of the utility model. Obviously, the described embodiment is a part of the embodiment of the utility model, not all of the embodiments. Based on the embodiment of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0019] In the following detailed description, reference may be made to the various specification drawings that are part of the present application and are used to illustrate specific embodiments of the present application. In the accompanying drawings, similar reference numerals describe substantially similar components in different figures. The various specific embodiments of the present application are described below in sufficient detail so that a person of ordinary skill in the art with relevant knowledge and skills in the art can implement the technical solutions of the present application. It should be understood that other embodiments may also be used or structural, logical or electrical changes may be made to the embodiments of the present application.

[0020] The "reagents" mentioned herein include all possible liquids, including but not limited to: diluents, washing solutions, water, blocking solutions, staining solutions, solvents containing active substances, secondary antibodies, substrates, etc.

[0021] The present application proposes a film stripping instrument, which includes: a film stripping platform, which includes a tray and a first motion component connected to the tray, the tray carries the paper to be stripped, and the first motion component controls the tray to move in the horizontal direction; a liquid adding mechanism, which includes a liquid adding needle and a second motion component, the liquid adding needle is connected to the second motion component, and is used to accommodate the reagent to pass through and stripe on the paper, and the second motion component controls the liquid adding needle to move in the vertical direction and vertical direction; a liquid injection mechanism, which includes a micro-injector and a micro-motion mechanism, one end of the micro-injector is connected to the liquid adding needle, and the other end is connected to the micro-motion mechanism, and is used to accommodate the reagent; the micro-motion mechanism is used to control the micro-injector to absorb or release the reagent; and a control box, which is used to control the first motion component, the second motion component and / or the micro-motion mechanism to move; wherein the micro-motion mechanism includes a reduction motor and a ball screw, and the nut on the ball screw is connected to the micro-injector. Thus, micro-liquid addition can be achieved, and the liquid addition is continuous and uniform.

[0022] In some embodiments, the lead of the ball screw is no greater than 1 mm, so that 0.5 μl / cm of liquid addition can be achieved, greatly improving the accuracy of micro-liquid addition.

[0023] In some embodiments, the micro-injector includes a cylinder and a piston, the cylinder includes a cylindrical cavity for accommodating a reagent, the end of the cylinder away from the piston includes an opening, the opening connects the cavity and the liquid-filling needle, and is used to accommodate the reagent in and out of the cavity; the piston is disposed in the cavity and is connected to the micro-motion mechanism to reciprocate in the cavity.

[0024] In some embodiments, the diameter of the cavity is no greater than 2.3 mm. The accuracy of micro-liquid addition can be further improved by using a micro-injector.

[0025] In some embodiments, the outer diameter of the liquid adding needle is less than 0.5 mm, and the inner diameter is not greater than 0.2 mm. By controlling the movement speed of the film-scratching platform and the movement speed of the micro-motion mechanism, uniform film-scratching lines can be achieved.

[0026] In some embodiments, the film scanning instrument further includes: a solenoid valve, which includes one or more inlets and one or more outlets, the microinjector and the liquid adding needle are connected to the outlet, and the inlet is connected to one or more reagent bottles containing reagents.

[0027] In some embodiments, the film scribing instrument further includes: a reagent rack for holding the reagent bottle.

[0028] In some embodiments, the film stripping instrument further includes a bracket, which is connected to the second motion component, and the liquid-adding needle is arranged on the bracket. In some embodiments, the bracket includes a connecting hole, which is used for the bracket to connect the liquid-adding needle. In some embodiments, the connecting hole is long and includes a plurality of connecting positions. Thus, the position of the liquid-adding needle can be adjusted to adapt to a variety of different film stripping situations, thereby improving the scope of application of the film stripping instrument.

[0029] The technical solution of the present application is further described below through specific embodiments. Those skilled in the art should understand that the following description is only for the convenience of understanding the technical solution of the application and should not be used to limit the protection scope of the present application.

[0030] Figure 1 Schematic diagram of a film scratching instrument according to one embodiment of the present application.

[0031] As shown in the figure, the film stripping instrument 100 includes a film stripping platform 110, a liquid adding mechanism 120, a liquid pumping mechanism 130 and a control box (not shown in the figure). Among them, the liquid adding mechanism 120 is arranged on one side of the film stripping platform 110 and extends to the film stripping platform 110, the liquid pumping mechanism 130 and the liquid adding mechanism 120 are arranged on the same side of the film stripping platform 110 and are connected to the liquid adding mechanism 120, and the control box is respectively connected to the film stripping platform 110, the liquid adding mechanism 120 and the liquid pumping mechanism 130, and can be used to control the movement of the film stripping platform 110, the liquid adding mechanism 120 and the liquid pumping mechanism 130.

[0032] In some embodiments, the film stripping instrument 100 may further include a housing 150, which may be disposed below the film stripping platform 110, the liquid adding mechanism 120, and the liquid pumping mechanism 130, and may be used to carry components such as the film stripping platform 110, the liquid adding mechanism 120, the liquid pumping mechanism 130, and a control box. In some embodiments, the housing 150 may be in the form of a frame plus a cover plate, which may improve the structural strength of the housing. In some embodiments, the control box may be disposed inside the housing, so that the control box may be protected. In some embodiments, at least part of the cover plate may be openable relative to the frame, so as to facilitate the later maintenance of the film stripping instrument. In some embodiments, the upper surface of the housing may be the working surface of the film stripping instrument, wherein the film stripping platform 110, the liquid adding mechanism 120, and the liquid pumping mechanism 130 are all disposed on the upper surface of the housing. In some embodiments, the control box may be disposed inside the housing, so that the control box may be protected.

[0033] In some embodiments, the film stripping instrument 100 may further include a protective cover (not shown in the figure), which may be disposed above the housing 150 and connected to one side of the housing 150, and may cover the structure disposed on the upper surface of the housing. In some embodiments, the protective cover or at least a portion of the protective cover is openable to facilitate the staff to operate the film stripping instrument. In some embodiments, the protective cover is at least partially transparent to facilitate the staff to observe the film stripping process.

[0034] In some embodiments, the film stripping platform 110 is arranged parallel to the side of the housing 150 and occupies about half of the area of ​​the upper surface of the housing. The film stripping platform 110 includes a tray 111 and a first motion component (not shown in the figure), wherein the tray 111 can be used to carry the paper to be stripped; the first motion component is arranged below the tray and can be used to control the tray to reciprocate in the horizontal direction, so as to facilitate the stripping of multiple stripes on the paper. In some embodiments, the first motion component may include a guide rail and a power source, wherein the guide rail is arranged above the horizontal and connected to the tray, so that the tray can reciprocate on the guide rail, and the power source can control the movement of the tray on the guide rail. In some embodiments, the power source can be a motor-driven gear rack structure, the rack is installed on the back of the tray, and the film stripping platform is driven to move linearly by controlling the rotation of a motor equipped with a gear meshing with the rack. In some embodiments, the power source can also be other structures. For example: a motor drives a worm gear structure, a cylinder, a hydraulic cylinder or a linear motor, etc.

[0035] In some embodiments, the liquid adding mechanism 120 and the liquid pumping mechanism 130 are disposed on the side of the upper surface of the housing 150 not occupied by the film stripping platform, and can be used to stripe the paper on the film stripping platform. In some embodiments, the liquid adding mechanism 120 is disposed near the center line of the housing 150 .

[0036] The specific structures of the liquid adding mechanism 120 and the liquid pumping mechanism 130 will be described in detail below.

[0037] Figure 2 Schematic diagram of a liquid adding mechanism according to an embodiment of the present application.

[0038] As shown in the figure, the liquid adding mechanism 120 includes a liquid adding needle 210 and a second moving component 220. The liquid adding needle 210 is connected to the second moving component 220, and can be used to accommodate the reagent to pass through and move on the paper of the film-scraping platform. The second moving component 220 can control the liquid adding needle 210 to move in the vertical direction and the vertical direction, and drive the liquid adding needle to scratch the paper.

[0039] In some embodiments, the outer diameter of the liquid adding needle is less than 0.5 mm, and the inner diameter is not greater than 0.2 mm. By controlling the movement speed of the film drawing platform and the movement speed of the micro-motion mechanism, the width of the film drawing line can be about 0.7 mm, which is conducive to the uniformity of the film drawing line, and can also make the film drawing line narrower, which is convenient for the preparation of the reagent kit. In some embodiments, the liquid adding needle may include an inlet 211, which may be connected to the liquid injection mechanism and may be used to accommodate the reagent into the liquid adding needle.

[0040] In some embodiments, the liquid adding mechanism 120 further includes a bracket 230, which connects the liquid adding needle 210 and the second moving assembly 220, and the liquid adding needle can be connected to the second moving assembly. In some embodiments, the bracket includes a connecting hole 231, which can be used to connect the liquid adding needle. The liquid adding needle is provided with a connector 211 that matches the connecting hole, and the liquid adding needle can be conveniently connected to the bracket. In some embodiments, the connecting hole 231 is in the shape of an elongated strip, and a plurality of connecting positions can be included thereon. The connector 211 can be connected to different connecting positions, which is convenient for adjusting the position of the liquid adding needle and can be adapted to the production of films of different specifications.

[0041] In some embodiments, the second motion assembly includes a lifting structure 221 and a linear structure 222. The lifting structure is a motor-driven worm gear structure. For example, the bracket 230 is connected to the turbine, the motor drives the worm to rotate, and the turbine meshing with the worm moves up and down, thereby driving the bracket to lift. In some embodiments, the lifting structure can also be in other forms. In some embodiments, the second motion assembly can also include a bracket 223, which can be used to support the lifting structure 221, so that the liquid addition needle can be driven to move in the vertical direction.

[0042] In some embodiments, the linear structure 222 is a chain drive. For example, a chain is connected to the bracket 223, and the motor drives the sprocket to rotate, and the chain meshed with the sprocket rotates, driving the bracket 223 to move. In some embodiments, the second motion component may also include a slide rail 224, which is disposed on the upper surface of the housing, and the bracket 223 is disposed on the slide rail 224. When the chain drives the bracket to move, the bracket moves along the slide rail 224, thereby driving the liquid-adding needle to move in the vertical direction.

[0043] Figure 3 Schematic diagram of a liquid pumping mechanism according to one embodiment of the present application.

[0044] As shown in the figure, the liquid injection mechanism 130 includes a micro-injector 310 and a micro-motion mechanism 320, wherein the first end of the micro-injector 310 is connected to the inlet of the liquid injection needle, and the second end is connected to the micro-motion mechanism 320 and can be used to accommodate the reagent; the micro-motion mechanism 320 is connected to the micro-injector and can be used to control the micro-injector to absorb or release the reagent. In some embodiments, the micro-injector 310 can be connected to the liquid injection needle through a connecting tube.

[0045] In some embodiments, the micro-injector 310 may include a cylinder 311 and a piston 312, wherein the cylinder 311 is hollow inside and includes a cylindrical cavity that can be used to accommodate reagents, and an opening 313 is included at one end of the cylinder 312 away from the piston 312, the opening 313 connects the cavity and the liquid adding needle, and can be used to connect with the connecting tube to accommodate the reagent in and out of the cavity; the piston 312 can be set in the cavity, and extend out of the cavity to connect to the micro-motion mechanism 320, and can reciprocate in the cavity under the control of the micro-motion mechanism. In some embodiments, the diameter of the cavity is not greater than 2,3mm, and the accuracy of micro-addition can be improved by reducing the inner diameter of the micro-injector.

[0046] In some embodiments, the micro-motion mechanism 320 includes a reduction motor 321 and a ball screw 322, wherein the nut on the ball screw 322 is connected to the portion of the piston 312 extending out of the cavity, and the ball screw is driven to rotate by the reduction motor, thereby driving the nut on the screw to move up and down at a uniform speed, and further driving the piston to reciprocate in the cavity, so as to achieve the micro-injector to absorb or release the reagent. In some embodiments, the lead of the ball screw is not greater than 1 mm, and the inner diameter of the micro-injector can be reduced by the precision screw, so that 0.5 microliters / cm of film can be achieved, thereby achieving the purpose of micro-addition.

[0047] In some embodiments, the liquid-dispensing mechanism 130 may further include a fixing frame 330, which may fix the micro-injector 310 and the micro-motion mechanism 320, and fix the two on the housing 150. In some further embodiments, the fixing frame 330 may be inserted into the upper surface of the housing 150, so that the reduction motor 321 may be disposed inside the housing.

[0048] In some embodiments, the film stripping instrument 100 may further include a solenoid valve 160, which may be disposed on a fixed frame 330 of the liquid injection mechanism 130, and may be connected to the liquid injection mechanism 120, the liquid injection mechanism 130, and a reagent bottle containing a reagent. In some embodiments, the solenoid valve 160 may include one or more inlets (not shown) and one or more outlets 161, wherein the opening 313 of the microinjector and the inlet 211 of the liquid injection needle are connected to the outlet 161 of the solenoid valve, and the inlet of the solenoid valve is connected to the reagent bottle containing the reagent. In some embodiments, different inlets may be connected to reagent bottles containing different reagents. In some embodiments, the film stripping instrument 100 may further include: a reagent rack 170, which is disposed on the upper surface of the casing and is close to the liquid injection mechanism, and may be used to carry a reagent bottle containing a reagent.

[0049] The film scratcher of this application can be used in different scenarios.

[0050] Scenario 1: Make a small-scale film, such as for experimental use. By connecting the micro-injector with the injection needle, the operator can place the reagent at the injection needle, and control the micro-injector to inhale the reagent through the injection needle. When film drawing is required, the reagent is removed, and the micro-injector is controlled to draw the film through the injection needle.

[0051] Scenario 2: Large-scale film production is controlled by solenoid valves. When the reagent needs to be drawn, the solenoid valve controls the reagent bottle to be connected to the micro-injector; when the film needs to be scratched, the solenoid valve controls the micro-injector to be connected to the injection needle.

[0052] The film drawing instrument of the present application is controlled by a micro-motion mechanism and can achieve micro-liquid addition when used in conjunction with a micro-injector. The lines drawn on the film are uniform, and a thinner liquid-adding needle can be used to make the lines drawn on the film narrower, which is beneficial to the preparation of the test kit.

[0053] The above embodiments are only used to illustrate the present invention, but not to limit the present invention. Ordinary technicians in the relevant technical field can make various changes and modifications without departing from the scope of the present invention. Therefore, all equivalent technical solutions should also fall within the scope of the present invention.

Claims

1. A film scratching instrument, characterized in that: include: The film stripping platform comprises a tray and a first motion component connected to the tray, the tray carries the paper to be stripped, and the first motion component controls the tray to move in a horizontal direction; A liquid adding mechanism, comprising a liquid adding needle and a second moving assembly, wherein the liquid adding needle is connected to the second moving assembly and is used to receive the reagent and pass through and slide on the paper, and the second moving assembly controls the liquid adding needle to move in a vertical direction and a vertical direction; The liquid injection mechanism comprises a micro-injector and a micro-motion mechanism, wherein one end of the micro-injector is connected to the liquid injection needle, and the other end is connected to the micro-motion mechanism and is used to contain the reagent; the micro-motion mechanism is used to control the micro-injector to absorb or release the reagent; and A control box, used for controlling the movement of the first motion assembly, the second motion assembly and / or the micro-motion mechanism; Wherein, the micro-motion mechanism includes a reduction motor and a ball screw, and the nut on the ball screw is connected to the micro-injector.

2. The film scratching instrument according to claim 1, characterized in that: The lead of the ball screw is no more than 1 mm.

3. The film scratching instrument according to claim 1, characterized in that: The micro-injector includes a cylinder and a piston. The cylinder includes a cylindrical cavity for accommodating reagents. The end of the cylinder away from the piston includes an opening, and the opening connects the cavity and the liquid-filling needle to accommodate the reagent in and out of the cavity. The piston is arranged in the cavity and is connected to the micro-motion mechanism to reciprocate in the cavity.

4. The film scratching instrument according to claim 3, characterized in that: The diameter of the cavity is no greater than 2.3 mm.

5. The film scratching instrument according to claim 1, characterized in that: The outer diameter of the liquid adding needle is less than 0.5 mm, and the inner diameter is not more than 0.2 mm.

6. The film scratching instrument according to claim 1, characterized in that: Further including: The solenoid valve comprises one or more inlets and one or more outlets, the micro-injector and the liquid adding needle are connected to the outlets, and the inlet is connected to one or more reagent bottles containing reagents.

7. The film scratching instrument according to claim 6, characterized in that: Further including: A reagent rack is used to carry the reagent bottles.

8. The film scratching instrument according to claim 1, characterized in that: It further comprises a bracket connected to the second motion component, and the liquid adding needle is arranged on the bracket.

9. The film scratching instrument according to claim 8, characterized in that: The bracket includes a connecting hole, which is used for the bracket to connect to the liquid adding needle.

10. The film scratching instrument according to claim 9, characterized in that: The connection hole is in the shape of an elongated strip and includes a plurality of connection positions thereon.

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