Detection device for production of human-derived recombinant triple-helix collagen

Abstract

The utility model discloses a detection device for production of human-derived recombinant triple-helix collagen. The detection device comprises a box body, a mounting seat, a mounting cavity, a filter screen cylinder and a scraping plate, according to the detection device for production of the human-derived recombinant triple-helix collagen, a crushing cavity, a protection cavity and a collection cavity are sequentially formed in a box body from top to bottom, a mounting seat matched with the protection cavity is slidably connected into the protection cavity, and a transversely-arranged filter screen cylinder is rotatably mounted in the mounting seat; a mounting cavity for rotationally mounting the filter screen cylinder is formed in the mounting base, a scraper plate attached to the filter screen cylinder is fixedly connected to one side of the mounting cavity, a collecting groove is formed in the position, corresponding to the scraper plate, of the mounting base, a first motor is fixedly mounted at the position, corresponding to the filter screen cylinder, of the box body, and the first motor and the filter screen cylinder are mounted in an assembled mode; the first motor drives the filter screen cylinder to rotate, and then the surface of the filter screen cylinder is cleaned through the scraping plate, so that the problem that the filtering efficiency is influenced by impurity accumulation can be effectively avoided.

Description

Technical Field

[0001] This utility model relates to the field of separation and detection devices, specifically a detection device for the production of human recombinant triple helix collagen. Background Technology

[0002] Type III collagen has been widely used in food, medicine, tissue engineering, cosmetics and other fields due to its good biocompatibility, biodegradability and bioactivity. Type III collagen separation and detection device is used to extract and separate type III collagen through a certain process.

[0003] A search revealed a patent document with publication number CN 220819579 U, which discloses a recombinant human type III collagen separation and detection device. The device includes a grinding chamber, a protective chamber fixedly connected to the bottom of the grinding chamber, a storage chamber fixedly connected to the bottom of the protective chamber, a baffle movably connected to the inner cavity of the protective chamber, and a first through groove on the top of the baffle. A filter body is fixedly connected to the inner cavity of the first through groove. This invention, by setting up a baffle, a first through groove, and a filter body, with the baffle supporting and fixing the filter body, improves the stability of the filter body during operation. The filter body is used to filter collagen. By pulling out the baffle, it can be removed from the protective chamber for cleaning. This solves the problem that if the filter is not cleaned for a long time, culture medium, various minerals, and other impurities will generate a large number of bacteria on the filter, which is not only unhygienic but also contaminates the collagen and reduces the quality of collagen extraction.

[0004] In the aforementioned prior art, although filtration can be performed using a filter screen, impurities accumulate on the surface of the filter screen during use, causing the mesh of the filter screen to become blocked and affecting the filtration efficiency. Therefore, a new detection device for the production of human recombinant triple helix collagen is proposed to optimize the aforementioned prior art. Utility Model Content

[0005] The purpose of this invention is to provide a detection device for the production of human recombinant triple helix collagen, so as to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] A testing device for the production of human recombinant triple-helix collagen includes a housing. The housing contains, from top to bottom, a crushing chamber, a protective chamber, and a collecting chamber. A mounting base adapted to the protective chamber is slidably connected to it. A horizontally arranged filter cylinder is rotatably mounted inside the mounting base. The mounting base has a mounting cavity for rotating the filter cylinder. A scraper that fits against the filter cylinder is fixedly connected to one side of the mounting cavity. A collecting groove is provided on the mounting base corresponding to the scraper. A first motor is fixedly mounted on the housing corresponding to the filter cylinder. The first motor and the filter cylinder are assembled together. A crushing mechanism is provided in the crushing chamber. A storage cabinet adapted to the collecting chamber is slidably connected to it. Guide strips are provided on both sides of the storage cabinet and the mounting base. Guide grooves are provided on the housing corresponding to the guide strips. The storage cabinet and the mounting base are slidably connected to the housing through the cooperation of the guide grooves and guide strips. A feeding port is provided on the top of the housing.

[0008] As a further embodiment of this utility model: the output end of the first motor is inserted into the housing and fixedly connected with an external hexagonal connector, and both ends of the filter screen are fixedly connected with internal hexagonal connectors. The internal hexagonal connectors correspond to and are compatible with the external hexagonal connectors, and the internal hexagonal connectors are rotatably and throughly connected to the mounting base.

[0009] As a further embodiment of this utility model: one side of the mounting base and the storage cabinet both protrude from the box body and are fixedly connected to a sealing plate. The outer side of the sealing plate is symmetrically provided with a pressure plate. Both ends of the pressure plate are provided with positioning grooves that are fixedly connected to the outer wall of the box body. The positioning groove is threadedly connected with a mating bolt. The positioning groove is an open groove and has a threaded hole for threaded connection of the mating bolt.

[0010] As a further embodiment of this utility model: the clamping bolt abuts against the pressure plate, and the pressure plate has a groove for the clamping bolt to abut against.

[0011] As a further improvement of this utility model, handles are fixedly connected to the front surface of each sealing plate.

[0012] As a further embodiment of this utility model: the crushing mechanism includes a crushing roller and a second motor. The crushing roller is rotatably installed in the crushing chamber inside the housing. The second motor is fixedly connected to the outer wall of the housing at a position corresponding to the end of the crushing roller. The output end of the second motor is fixedly connected to the crushing roller.

[0013] As a further improvement of this utility model: both the first motor and the second motor are externally connected to a power supply and a switch.

[0014] Compared with the prior art, the beneficial effects of this utility model are:

[0015] 1. This utility model uses a first motor to drive the filter cylinder to rotate, and then uses a scraper to clean the surface of the filter cylinder, thereby effectively avoiding the problem of impurities accumulating and affecting the filtration efficiency.

[0016] 2. The first motor of this utility model is assembled with the filter screen cylinder through an external hexagonal connector and an internal hexagonal connector, which facilitates the formation of a transmission connection after the mounting base is inserted into the box.

[0017] 3. This utility model uses a pressure plate inserted into a positioning groove, and further uses a tightening bolt to press into the groove, thereby pressing and fixing the sealing plate by the pressure plate, so that the mounting base and storage cabinet are fixed after being inserted into the box.

[0018] 4. This utility model can drive the crushing roller to rotate through the second motor, thereby crushing and stirring the cell fluid put into the box, thus facilitating the separation of collagen. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of a detection device for the production of human recombinant triple-helix collagen.

[0020] Figure 2 This is a front view of a detection device for the production of human recombinant triple helix collagen.

[0021] Figure 3 This is a front cross-sectional view of a detection device for the production of human recombinant triple helix collagen.

[0022] Figure 4 This is a diagram showing the mounting base in a testing device for the production of human recombinant triple-helix collagen.

[0023] Figure 5 This is a diagram illustrating the positioning groove in a testing device for the production of human recombinant triple-helix collagen.

[0024] In the diagram: 1. Housing; 2. Mounting base; 3. Filter screen cylinder; 4. Mounting cavity; 5. Scraper; 6. Collection trough; 7. First motor; 8. Storage cabinet; 9. External hexagonal connector; 10. Internal hexagonal connector; 11. Sealing plate; 12. Pressure plate; 13. Second motor; 14. Positioning groove; 15. Tightening bolt; 16. Support groove; 17. Handle; 18. Crushing roller. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0026] Please see Figures 1-5 In this embodiment of the present invention, a detection device for the production of human recombinant triple helix collagen includes a housing 1. The housing 1 has a crushing chamber, a protective chamber, and a collection chamber arranged sequentially from top to bottom inside. A mounting base 2 adapted to the protective chamber is slidably connected inside the protective chamber. A horizontally arranged filter cylinder 3 is rotatably installed inside the mounting base 2. The mounting base 2 has a mounting cavity 4 for rotatably installing the filter cylinder 3. A scraper 5 that fits against the filter cylinder 3 is fixedly connected to one side of the mounting cavity 4. A collection groove 6 is opened on the mounting base 2 corresponding to the scraper 5. A first motor 7 is fixedly installed on the housing 1 corresponding to the filter cylinder 3. The first motor 7 and the filter cylinder 3 are assembled. A crushing mechanism is provided in the crushing chamber. A storage cabinet 8 adapted to the collection chamber is slidably connected inside the collection chamber. Guide strips are provided on both sides of the storage cabinet 8 and the mounting base 2. Guide grooves are opened on the housing 1 corresponding to the guide strips. The storage cabinet 8 and the mounting base 2 are slidably connected inside the housing 1 through the cooperation of the guide grooves and guide strips. A feeding port is provided on the top of the housing 1.

[0027] The first motor 7 drives the filter cylinder 3 to rotate, and the scraper 5 cleans the surface of the filter cylinder 3, thereby effectively avoiding the problem of impurities accumulating and affecting the filtration efficiency.

[0028] The output end of the first motor 7 is inserted into the housing 1 and fixedly connected to an external hexagonal connector 9. Both ends of the filter cylinder 3 are fixedly connected to internal hexagonal connectors 10. The internal hexagonal connectors 10 correspond to and fit with the external hexagonal connectors 9. The internal hexagonal connectors 10 are rotatably connected to the mounting base 2. Internal hexagonal connectors 10 are provided on both sides, allowing the filter cylinder 3 to be manually rotated, facilitating the alignment of the internal hexagonal connectors 10 and external hexagonal connectors 9 for easy insertion.

[0029] The first motor 7 is assembled with the filter cylinder 3 via an external hexagonal connector 9 and an internal hexagonal connector 10, thus facilitating the formation of a transmission connection after the mounting base 2 is inserted into the housing 1.

[0030] Both the mounting base 2 and the storage cabinet 8 extend out of the box body 1 on one side and are fixedly connected to the sealing plate 11. The outer side of the sealing plate 11 is symmetrically provided with pressure plate 12. Both ends of the pressure plate 12 are provided with positioning grooves 14 that are fixedly connected to the outer wall of the box body 1. The positioning groove 14 is threaded with a matching tightening bolt 15. The positioning groove 14 is an open groove, and the positioning groove 14 is provided with threaded holes for threaded connection of the tightening bolt 15.

[0031] The clamping bolt 15 abuts against the pressure plate 12, and the pressure plate 12 has a groove 16 for clamping the clamping bolt 15.

[0032] Handles 17 are fixedly connected to the front surface of the sealing plate 11. The mounting base 2 and storage cabinet 8 can be pulled out after the pressure plate 12 is removed by using the handles 17.

[0033] The pressure plate 12 is inserted into the positioning groove 14, and the clamping bolt 15 is further inserted into the groove 16, thereby pressing and fixing the sealing plate 11 by the pressure plate 12, so that the mounting base 2 and the storage cabinet 8 are fixed after being inserted into the box body 1.

[0034] The crushing mechanism includes a crushing roller 18 and a second motor 13. The crushing roller 18 is rotatably installed in the crushing chamber inside the housing 1. The second motor 13 is fixedly connected to the outer wall of the housing 1 at the end corresponding to the end of the crushing roller 18. The output end of the second motor 13 is fixedly connected to the crushing roller 18.

[0035] The second motor 13 can drive the crushing roller 18 to rotate, thereby crushing and stirring the cell fluid put into the box 1, thus facilitating the separation of collagen.

[0036] Both the first motor 7 and the second motor 13 are externally connected to a power supply and a switch.

[0037] The working principle of this utility model is as follows:

[0038] In use, cell fluid is added through the feeding port. The second motor 13 drives the pulverizing roller 18 to rotate. When the pulverizing roller 18 rotates, the cell fluid is stirred, creating a pulverizing environment that allows collagen to be extracted from the cell fluid. The collagen is then filtered through the filter cylinder 3, passes through the mounting cavity 4 on the mounting base 2, and flows into the inner cavity of the storage cabinet 8 for collection, thus achieving collagen extraction. At this time, the first motor 7 drives the filter cylinder 3 through the cooperation of the external hexagonal connector 9 and the internal hexagonal connector 10. The filter cylinder 3 rotates slowly, and the surface of the rotating filter cylinder 3 is cleaned by the scraper 5 to prevent impurities from accumulating on the filter cylinder 3 and affecting the filtration efficiency of the filter cylinder 3. At this time, the clamping bolt 15 can be loosened, and the pressure plate 12 can be removed. Then, the mounting base 2 and the storage cabinet 8 can be pulled out by the handle 17, and the mounting base 2 and the filter cylinder 3 installed in it can be completely tilted. At the same time, the collagen collected in the storage cabinet 8 can be collected. The collected collagen can be weighed and compared to detect the collagen yield of the raw material.

[0039] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A detection device for the production of human recombinant triple-helix collagen, comprising a housing (1), characterized in that: The interior of the box (1) is provided with a crushing chamber, a protective chamber and a collecting chamber from top to bottom. A mounting base (2) adapted to it is slidably connected in the protective chamber. A horizontally arranged filter cylinder (3) is rotatably installed in the mounting base (2). The mounting base (2) is provided with a mounting cavity (4) for the rotating installation of the filter cylinder (3). A scraper (5) that fits against the filter cylinder (3) is fixedly connected to one side of the mounting cavity (4). A collecting groove (6) is opened in the mounting base (2) corresponding to the scraper (5). A first motor (7) is fixedly installed in the box (1) corresponding to the filter cylinder (3). The first motor (7) and the filter cylinder (3) are assembled. A crushing mechanism is provided in the crushing chamber. A storage cabinet (8) adapted to it is slidably connected in the collecting chamber. A feeding port is provided on the top of the box (1).

2. The detection device for the production of human recombinant triple-helix collagen according to claim 1, characterized in that: The output end of the first motor (7) is inserted into the housing (1) and fixedly connected to an external hexagonal connector (9). Both ends of the filter screen cylinder (3) are fixedly connected to internal hexagonal connectors (10). The internal hexagonal connectors (10) correspond to and are compatible with the external hexagonal connectors (9). The internal hexagonal connectors (10) are rotatably connected to the mounting base (2).

3. The detection device for the production of human recombinant triple-helix collagen according to claim 1, characterized in that: The mounting base (2) and the storage cabinet (8) both extend out of the box body (1) and are fixedly connected to a sealing plate (11). The outer side of the sealing plate (11) is symmetrically provided with a pressure plate (12). Both ends of the pressure plate (12) are provided with positioning grooves (14) that are fixedly connected to the outer wall of the box body (1). The positioning grooves (14) are threaded with a matching tightening bolt (15).

4. The detection device for the production of human recombinant triple-helix collagen according to claim 3, characterized in that: The clamping bolt (15) abuts against the pressure plate (12), and the pressure plate (12) has a groove (16) for clamping the clamping bolt (15).

5. The detection device for the production of human recombinant triple-helix collagen according to claim 3, characterized in that: Each of the sealing plates (11) has a handle (17) fixedly connected to its front surface.

6. The detection device for the production of human recombinant triple-helix collagen according to claim 1, characterized in that: The crushing mechanism includes a crushing roller (18) and a second motor (13). The crushing roller (18) is rotatably installed in the crushing chamber inside the housing (1). The second motor (13) is fixedly connected to the outer wall of the housing (1) at the end corresponding to the end of the crushing roller (18). The output end of the second motor (13) is fixedly connected to the crushing roller (18).

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