A sampling device for the preparation of tetanus human immunoglobulin
By introducing a low-temperature temporary storage and automatic sampling mechanism into the sampling device, the problem of sample deterioration in the sampling device is solved, and low-temperature storage and automated operation of samples are realized, ensuring the accuracy of biochemical analysis and the convenience of operation.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- BANGHE PHARMA CO LTD
- Filing Date
- 2024-12-20
- Publication Date
- 2026-06-02
AI Technical Summary
Existing sampling devices do not have low-temperature storage capabilities, which makes samples susceptible to deterioration due to ambient temperature when temporarily stored inside the sampling device, thus affecting the accuracy of biochemical analysis.
A sampling device was designed, which includes a low-temperature temporary storage mechanism and an automatic sampling mechanism. The low-temperature temporary storage mechanism consists of a first support ring, a support outer cylinder, a second support ring, and a copper inner cylinder, and uses a low-temperature medium to cool and store the sample. The automatic sampling mechanism consists of an air suction pump, an air filling pump, and a movable cover, and realizes automatic sampling and sample release functions.
This method enables low-temperature storage of samples, avoids deterioration, ensures the accuracy of biochemical analysis, and reduces the workload of operators.
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Figure CN224317353U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the technical field of human immunoglobulin preparation devices, specifically to a sampling device for preparing tetanus human immunoglobulin. Background Technology
[0002] Tetanus immunoglobulin is a specific immune plasma obtained after immunizing healthy blood donors with adsorbed tetanus vaccine. This product contains specific tetanus antibodies, which neutralize tetanus toxin. Once in the human body, it provides patients with a timely and rapid supply of high-titer tetanus antibodies, thus playing a role in emergency treatment and passive immunization. The preparation of tetanus immunoglobulin requires biochemical analysis. This analysis involves collecting samples using a sampling device and then transporting them to the detection instrument for testing.
[0003] Existing sampling devices do not have the function of low-temperature storage. When samples are temporarily stored inside the sampling device, they are affected by the ambient temperature, which can easily lead to sample deterioration and affect the accuracy of biochemical analysis. Utility Model Content
[0004] The purpose of this invention is to provide a sampling device for the preparation of tetanus human immunoglobulin, which solves the problem that samples are easily deteriorated by ambient temperature when temporarily stored inside the sampling device in the prior art.
[0005] This utility model provides the following technical solution: a sampling device for preparing tetanus human immunoglobulin, including a sampling tube, a low-temperature temporary storage mechanism provided on the outer wall of the sampling tube, and an automatic sampling mechanism provided on the sampling tube.
[0006] The low-temperature temporary storage mechanism includes a first support ring, a support outer cylinder fixedly installed at the bottom of the first support ring, a second support ring fixedly installed at the bottom of the support outer cylinder, a copper inner cylinder located in the inner cavity of the support leg fixedly installed between the first and second support rings on adjacent sides, the copper inner cylinder being fixedly connected to the outer wall of the sampling cylinder, and a support leg fixedly installed on the outer wall of the support outer cylinder.
[0007] As a preferred embodiment of the above technical solution, both the first support ring and the second support ring are provided with through holes, and a rubber cone plug is movably inserted into the inner cavity of the through hole.
[0008] The above technical solution, through the design of the through hole and rubber cone plug, makes it easy for operators to add and replace the cryogenic medium.
[0009] As a preferred embodiment of the above technical solution, a digital thermometer is fixedly installed on the front of the outer support cylinder, and the measuring end of the digital thermometer extends into the inner cavity of the outer support cylinder.
[0010] The above technical solution, through the design of a digital thermometer, facilitates the operator's monitoring of the temperature of low-temperature media.
[0011] As a preferred embodiment of the above technical solution, the automatic sampling mechanism includes an air suction pump, an air inflation pump, a movable cover, and a top plate. The top plate is fixedly installed on the top of the sampling cylinder. The working pipe of the air suction pump is threadedly connected to the top of the top plate, and the working pipe of the air inflation pump is also threadedly connected to the top of the top plate.
[0012] Through the above technical solution, the design of the suction pump and the inflation pump can realize the function of automatic sampling or release.
[0013] As a preferred embodiment of the above technical solution, a protruding pipe opening is fixedly connected to the top of the top plate, and a flexible tube is movably inserted into the top of the protruding pipe opening.
[0014] The above technical solution, through the design of the flexible tube, makes it easy for the operator to adjust the sampling or placement position.
[0015] As a preferred embodiment of the above technical solution, the bottom of the top plate is fixedly connected to an extension tube located in the inner cavity of the sampling cylinder, the inner cavity of the extension tube is connected to the inner cavity of the protruding tube opening, the movable cover is movably inserted into the bottom of the sampling cylinder, a rubber ring is fixedly sleeved on the outer wall of the movable cover, the outer wall of the rubber ring is movably connected to the inner wall of the sampling cylinder, and a groove is provided on the top of the movable cover.
[0016] The above technical solution, through the design of the rubber ring, can seal the movable cover after insertion.
[0017] As a preferred embodiment of the above technical solution, a protrusion is fixedly installed on the outer wall of the movable cover, and a positioning bolt is threadedly connected to the protrusion, the threaded end of the positioning bolt being movably connected to the outer wall of the sampling cylinder.
[0018] The above technical solution, through the design of protrusions and positioning bolts, can lock the position of the movable cover after insertion.
[0019] Compared with the prior art, the beneficial effects of this utility model are:
[0020] This invention, through the design of a low-temperature temporary storage mechanism, can store a low-temperature medium in the cavity formed by the first support ring, the outer support cylinder, the second support ring, and the copper inner cylinder. The low-temperature medium can pass through the copper inner cylinder to cool the inner cavity of the sampling cylinder, thus realizing the function of low-temperature storage of the sample inside the sampling cylinder. This avoids the problem that the sample inside the sampling cylinder is prone to deterioration during the temporary storage process due to high ambient temperature, ensuring the accuracy of biochemical analysis. Through the design of the automatic sampling mechanism, it can realize the function of automatic sample extraction and output, reducing the labor intensity of the operator and increasing the practicality of this structure. Attached Figure Description
[0021] Figure 1 This is a perspective view of the present utility model;
[0022] Figure 2 This is a schematic diagram of the low-temperature temporary storage mechanism of this utility model;
[0023] Figure 3 This is a schematic diagram of the overall exploded structure of the outer support cylinder of this utility model;
[0024] Figure 4 This is a cross-sectional structural diagram of the sampling cylinder of this utility model.
[0025] In the diagram: 1. Sampling cylinder; 2. Low-temperature storage mechanism; 21. Support ring 1; 22. Support outer cylinder; 23. Support ring 2; 24. Support leg; 25. Through hole; 26. Rubber cone plug; 27. Copper inner cylinder; 28. Digital thermometer; 3. Automatic sampling mechanism; 31. Suction pump; 32. Inflation pump; 33. Extension tube; 34. Movable cover; 35. Groove; 36. Flexible hose. Detailed Implementation
[0026] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention.
[0027] like Figures 1-4As shown, this utility model provides a technical solution: a sampling device for preparing tetanus human immunoglobulin, including a sampling cylinder 1, a low-temperature temporary storage mechanism 2 provided on the outer wall of the sampling cylinder 1, an automatic sampling mechanism 3 provided on the sampling cylinder 1, the low-temperature temporary storage mechanism 2 including a first support ring 21, a support outer cylinder 22 fixedly installed at the bottom of the first support ring 21, a second support ring 23 fixedly installed at the bottom of the support outer cylinder 22, and a support ring 23 fixedly installed between adjacent sides of the first support ring 21 and the second support ring 23. The inner copper cylinder 27 is fixedly connected to the outer wall of the sampling cylinder 1. The support leg 24 is fixedly installed on the outer wall of the support outer cylinder 22. Before sampling, a low-temperature medium is added to the cavity formed by the first support ring 21, the support outer cylinder 22, the second support ring 23 and the inner copper cylinder 27. The low-temperature medium is water at near zero degrees. The low-temperature medium can pass through the inner copper cylinder 27 to cool the inner cavity of the sampling cylinder 1, thus realizing the function of low-temperature storage of the sample inside the sampling cylinder 1.
[0028] As one implementation method in this embodiment, such as Figure 3 As shown, both the first support ring 21 and the second support ring 23 have through holes 25. A rubber cone plug 26 is movably inserted into the inner cavity of the through hole 25. A digital thermometer 28 is fixedly installed on the front of the outer support cylinder 22. The temperature measuring end of the digital thermometer 28 extends into the inner cavity of the outer support cylinder 22. After the rubber cone plug 26 on the first support ring 21 is pulled out, it is easy to add a low-temperature medium into the inner cavity of the outer support cylinder 22 through the through hole 25 on the first support ring 21. After the rubber cone plug 26 on the second support ring 23 is pulled out, it is easy to discharge the low-temperature medium inside the outer support cylinder 22 through the through hole 25 on the second support ring 23. Through the design of the digital thermometer 28, the temperature of the low-temperature medium inside the outer support cylinder 22 can be monitored and displayed, which is convenient for the operator to observe. When the low-temperature medium cannot effectively cool the sample, it can be replaced in time to ensure the low-temperature storage effect of this structure on the sample.
[0029] As one implementation method in this embodiment, such as Figure 1 , Figure 4As shown, the automatic sampling mechanism 3 includes an air intake pump 31, an air inflation pump 32, a movable cover 34, and a top plate. The top plate is fixedly installed on the top of the sampling cylinder 1. The working pipe of the air intake pump 31 is threadedly connected to the top of the top plate, and the working pipe of the air inflation pump 32 is also threadedly connected to the top of the top plate. A protruding pipe opening is fixedly connected to the top of the top plate, and a flexible tube 36 is movably inserted into the top of the protruding pipe opening. An extension tube 33 located in the inner cavity of the sampling cylinder 1 is fixedly connected to the bottom of the top plate. The inner cavity of the extension tube 33 communicates with the inner cavity of the protruding pipe opening. The movable cover 34 is movably inserted into the bottom of the sampling cylinder 1. A rubber ring is fixedly fitted on the outer wall of the movable cover 34, and the outer wall of the rubber ring is movably connected to the inner wall of the sampling cylinder 1. A groove 35 is provided on the top of the movable cover 34, and a protruding pipe opening is fixedly installed on the outer wall of the movable cover 34. The sampling cylinder 1 has a raised block with a threaded positioning bolt. The threaded end of the positioning bolt is movably connected to the outer wall of the sampling cylinder 1. When sampling, the needle is inserted into the end of the flexible tube 36 and then inserted into the sampling point. The suction pump 31 is controlled to work, so that a negative pressure is generated in the inner cavity of the sampling cylinder 1. The sample can then be drawn into the inner cavity of the sampling cylinder 1 through the flexible tube 36 for storage. When the sample is output, the inflation pump 32 is controlled to work, so that the air pressure in the inner cavity of the sampling cylinder 1 is increased. The sample can then be discharged through the extension tube 33 and the flexible tube 36, realizing the automatic suction and discharge function and reducing the labor intensity of the operator. If it is necessary to clean the inner cavity of the sampling cylinder 1, the positioning bolt on the raised block is loosened, and the movable cover 34 is pulled out from the bottom of the sampling cylinder 1. Then the inner cavity of the sampling cylinder 1 can be cleaned.
[0030] Working principle: Before sampling, the rubber cone plug 26 on the first support ring 21 is pulled out, and then a low-temperature medium is added to the inside of the outer support cylinder 22 through the through hole 25 on the first support ring 21. During sampling, the needle is inserted into the end of the hose 36 and then inserted into the sampling point. The suction pump 31 is controlled to work, so that a negative pressure is generated in the inner cavity of the sampling cylinder 1. The sample can then be drawn into the inner cavity of the sampling cylinder 1 through the hose 36 for storage. When the sample is output, the inflation pump 32 is controlled to work, so that the air pressure in the inner cavity of the sampling cylinder 1 increases, and the sample can be discharged through the extension tube 33 and the hose 36. When the sample is temporarily stored in the inner cavity of the sampling cylinder 1, the low-temperature medium can pass through the copper inner cylinder 27 to cool the inner cavity of the sampling cylinder 1, thus realizing the function of low-temperature storage of the sample inside the sampling cylinder 1.
[0031] The above embodiments are only used to illustrate the technical solution of this utility model, and are not intended to limit it.
Claims
1. A sampling device for preparing tetanus human immunoglobulin, comprising a sampling tube (1), characterized in that: The sampling tube (1) is provided with a low temperature temporary storage mechanism (2) on its outer wall and an automatic sampling mechanism (3) on its surface. The low-temperature temporary storage mechanism (2) includes a first support ring (21), a support outer cylinder (22) is fixedly installed at the bottom of the first support ring (21), a second support ring (23) is fixedly installed at the bottom of the support outer cylinder (22), a copper inner cylinder (27) located in the inner cavity of the support leg (24) is fixedly installed between the first support ring (21) and the second support ring (23) on adjacent sides, the copper inner cylinder (27) is fixedly connected to the outer wall of the sampling cylinder (1), and the support leg (24) is fixedly installed on the outer wall of the support outer cylinder (22).
2. The sampling device for preparing tetanus human immunoglobulin according to claim 1, characterized in that: Both the first support ring (21) and the second support ring (23) have through holes (25), and a rubber cone plug (26) is movably inserted into the inner cavity of the through hole (25).
3. The sampling device for preparing tetanus human immunoglobulin according to claim 1, characterized in that: A digital thermometer (28) is fixedly installed on the front of the outer support cylinder (22), and the measuring end of the digital thermometer (28) extends into the inner cavity of the outer support cylinder (22).
4. The sampling device for preparing tetanus human immunoglobulin according to claim 1, characterized in that: The automatic sampling mechanism (3) includes an air intake pump (31), an air filling pump (32), a movable cover (34), and a top plate. The top plate is fixedly installed on the top of the sampling cylinder (1). The working pipe of the air intake pump (31) is threadedly connected to the top of the top plate, and the working pipe of the air filling pump (32) is threadedly connected to the top of the top plate.
5. The sampling device for preparing tetanus human immunoglobulin according to claim 4, characterized in that: The top of the top plate is fixedly connected to a protruding pipe opening, and a flexible tube (36) is movably inserted into the top of the protruding pipe opening.
6. The sampling device for preparing tetanus human immunoglobulin according to claim 5, characterized in that: The bottom of the top plate is fixedly connected to an extension tube (33) located in the inner cavity of the sampling cylinder (1). The inner cavity of the extension tube (33) is connected to the inner cavity of the protruding tube opening. The movable cover (34) is movably inserted into the bottom of the sampling cylinder (1). A rubber ring is fixedly sleeved on the outer wall of the movable cover (34). The outer wall of the rubber ring is movably connected to the inner wall of the sampling cylinder (1). A groove (35) is provided on the top of the movable cover (34).
7. The sampling device for preparing tetanus human immunoglobulin according to claim 6, characterized in that: A protrusion is fixedly installed on the outer wall of the movable cover (34), and a positioning bolt is threadedly connected to the protrusion. The threaded end of the positioning bolt is movably connected to the outer wall of the sampling cylinder (1).