A flow path of a rapid solvent extractor integrating extraction and concentration

Abstract

The utility model discloses a kind of extraction and concentration integrated fast solvent extraction instrument flow path, it is related to solvent extraction instrument technical field, the flow path includes extraction flow path and concentration flow path, extraction flow path includes gas supply flow path, liquid supply flow path and several extraction branch, any extraction branch includes first pipeline, and first pressure sensor, extraction unit, condenser and lower three-way valve are sequentially arranged on first pipeline, the first end of first pipeline is communicated with upper three-way valve, the tail end of first pipeline is communicated with collection bottle, collection bottle is set on heating block;Liquid supply flow path and gas supply flow path are connected with upper three-way valve pipeline;One end of concentration flow path is communicated with the gas inlet end of gas supply flow path, other end is communicated with first pipeline, the communication of concentration flow path and first pipeline is located between lower three-way valve and collection bottle.The high-pressure extraction flow path is merged with nitrogen blow concentration flow path, can realize the optimized integrated use of instrument, reduce customer purchase concentration instrument, realize the demand of cost reduction.

Description

Technical Field

[0001] This utility model relates to the field of solvent extraction instrument technology, and more specifically, to a flow path for a rapid solvent extraction instrument that integrates extraction and concentration. Background Technology

[0002] Rapid solvent extraction (RFE) is a highly efficient sample pretreatment device that accelerates the solvent extraction process under high temperature and high pressure conditions. Its core principles are: ① High temperature accelerates molecular motion: By increasing the temperature, the mass transfer rate between the target compound and the solvent is accelerated, significantly shortening the extraction time; ② High pressure maintains the solvent in a liquid state: Maintaining the solvent in a liquid state at high temperature enhances its permeability to the sample matrix and its solubility of the target compound; ③ Automated process: Integrating sample loading, extraction, and collection steps reduces human intervention errors. RFEs are widely used in environmental science (such as the detection of polycyclic aromatic hydrocarbons and dioxins in soil), food safety (such as pesticide residue analysis in agricultural products), and pharmaceuticals (drug component extraction) and other fields.

[0003] Nitrogen blowing technology is a processing technique that uses nitrogen gas to purge and heat the sample surface, disrupting the gas-liquid equilibrium and accelerating solvent evaporation to achieve sample concentration. Its core advantages include: ① Rapid concentration: The flow of nitrogen gas reduces the partial pressure of the solvent, and combined with heating (typically 40-60℃), the evaporation rate is increased several times, shortening the concentration time for a single sample to 10-20 minutes; ② Oxygen-free protection: The inert environment of nitrogen prevents oxidation of the target analyte, making it particularly suitable for easily oxidized substances; ③ High-throughput processing: It can process multiple samples simultaneously, significantly improving efficiency; ④ Solvent compatibility: It is suitable for common solvents such as water, methanol, and acetonitrile, and requires no vacuum system, making it easy to operate. Nitrogen blowing technology has been maturely applied in fields such as pesticide residue analysis, environmental monitoring, and pharmaceutical quality control, and seamlessly integrates with analytical instruments such as GC-MS and HPLC.

[0004] Although rapid solvent extraction (XSER) and nitrogen blowing technology each have significant advantages, combining the two (i.e., integrating extraction and concentration into one device) still faces the following technical bottlenecks: ① Process breakpoint problem: The liquid extracted by the XSER needs to be transferred to a separate nitrogen blowing device, increasing the number of operation steps and the risk of contamination; ② Risk of degradation of heat-sensitive compounds: The external nitrogen blowing device needs to be heated for a long time, which may damage the thermally unstable target substances. Utility Model Content

[0005] The purpose of this invention is to overcome the shortcomings of the existing technology and provide a flow path for a rapid solvent extraction instrument that integrates extraction and concentration.

[0006] The objective of this utility model is achieved through the following technical solution:

[0007] A rapid solvent extractor flow path integrating extraction and concentration includes an extraction flow path and a concentration flow path. The extraction flow path includes a gas supply flow path, a liquid supply flow path, and several extraction branches. Each extraction branch includes a first pipeline and a first pressure sensor, an extraction unit, a condenser, and a lower three-way valve sequentially arranged on the first pipeline. The first end of the first pipeline is connected to an upper three-way valve, and the tail end of the first pipeline is connected to a collection bottle, which is mounted on a heating block. The liquid supply flow path and the gas supply flow path are both connected to the upper three-way valve pipeline. One end of the concentration flow path is connected to the gas inlet of the gas supply flow path, and the other end is connected to the first pipeline. The connection point between the concentration flow path and the first pipeline is located between the lower three-way valve and the collection bottle.

[0008] Furthermore, in this utility model, the extraction unit includes an upper sealing seat, a heating unit, and a lower sealing seat arranged in sequence. The heating unit is provided with an extraction tube that is open at both ends. The upper sealing seat and the lower sealing seat are respectively used to seal the top and bottom ends of the extraction tube. The liquid in the first pipeline can flow into the extraction tube through the upper sealing seat, and the liquid in the extraction tube can flow into the condenser through the lower sealing seat.

[0009] Furthermore, in this utility model, the aforementioned gas supply path includes a first proportional valve and a gas multi-channel diversion module. The gas multi-channel diversion module has an inlet and several outlets. The inlet of the first proportional valve is connected to an inlet pipe. The outlet of the first proportional valve and the inlet of the gas multi-channel diversion module are connected through a gas supply pipe. Several outlets of the gas multi-channel diversion module are respectively connected to several of the aforementioned upper three-way valve pipelines.

[0010] Furthermore, in this utility model, the above-mentioned liquid supply flow path includes a mixing valve, a high-pressure pump, a second pressure sensor, and a liquid multi-channel diversion module connected in sequence by pipelines, and several outlets of the above-mentioned liquid multi-channel diversion module are respectively connected to several of the above-mentioned upper three-way valve pipelines.

[0011] Furthermore, in this utility model, the above-mentioned concentration flow path includes a second proportional valve and a nitrogen distribution block. The nitrogen distribution block has an inlet and several outlets. The inlet of the second proportional valve is connected to the inlet pipe through a second pipeline. The outlet of the second proportional valve is connected to the inlet of the nitrogen distribution block through a third pipeline. The several outlets of the nitrogen distribution block are respectively connected to several first pipelines through several fourth pipelines.

[0012] Furthermore, in this utility model, a one-way valve is provided on any of the aforementioned fourth pipelines.

[0013] Furthermore, in this invention, the aforementioned liquid multi-channel diversion module is also connected to an overpressure protection valve via a pipeline.

[0014] Furthermore, in this invention, any of the above-mentioned collection bottles is also connected to an exhaust pipe.

[0015] Furthermore, in this invention, the aforementioned three-way valve is also connected to a waste liquid collection block via a pipeline.

[0016] The beneficial effects of this utility model are:

[0017] This invention provides a flow path for a rapid solvent extractor that integrates extraction and concentration. The high-pressure extraction flow path and the nitrogen blowing concentration flow path are combined, which can realize the optimized integrated use of the instrument, reduce the need for customers to purchase concentrators, and achieve the goal of cost reduction. Attached Figure Description

[0018] Figure 1 This is a structural schematic diagram of an embodiment of the present utility model.

[0019] In the diagram: 1-First pipeline; 2-First pressure sensor; 3-Condenser; 4-Lower three-way valve; 5-Upper three-way valve; 6-Collection bottle; 7-Heating block; 8-Upper sealing seat; 9-Lower sealing seat; 10-Extraction tube; 11-First proportional valve; 12-Gas multi-channel diversion module; 13-Inlet pipe; 14-Gas supply pipe; 15-Mixing valve; 16-High-pressure pump; 17-Second pressure sensor; 18-Liquid multi-channel diversion module; 19-Second proportional valve; 20-Nitrogen diversion block; 21-Second pipeline; 22-Third pipeline; 23-Fourth pipeline; 24-Check valve; 25-Overpressure protection valve; 26-Exhaust pipe; 27-Waste liquid collection block. Detailed Implementation

[0020] The technical solution of this utility model will be clearly and completely described below with reference to the embodiments. Obviously, the described embodiments are only some embodiments of this utility model, and not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.

[0021] Please see Figure 1 This utility model provides a technical solution:

[0022] A rapid solvent extractor flow path integrating extraction and concentration includes an extraction flow path and a concentration flow path. The extraction flow path includes a gas supply flow path, a liquid supply flow path, and several extraction branches (six groups of extraction branches in this embodiment). Each extraction branch includes a first pipeline 1, and a first pressure sensor 2, an extraction unit, a condenser 3, and a lower three-way valve 4 sequentially installed on the first pipeline 1. The first end of the first pipeline 1 is connected to an upper three-way valve 5, and the last end of the first pipeline 1 is connected to a collection bottle 6, which is mounted on a heating block 7. The function of the first pressure sensor 2 is to detect whether the pressure in the extraction branch is normal. Both the liquid supply flow path and the gas supply flow path are connected to the upper three-way valve 5. One end of the concentration flow path is connected to the inlet end of the gas supply flow path, and the other end is connected to the first pipeline 1. The connection point between the concentration flow path and the first pipeline 1 is located between the lower three-way valve 4 and the collection bottle 6.

[0023] In this embodiment, the extraction unit includes an upper sealing seat 8, a heating unit (not shown in the figure), and a lower sealing seat 9 arranged sequentially. The heating unit has an extraction tube 10 with both ends open. The upper sealing seat 8 and the lower sealing seat 9 are used to seal the top and bottom ends of the extraction tube 10, respectively. Liquid in the first pipeline 1 can flow into the extraction tube 10 through the upper sealing seat 8, and liquid in the extraction tube 10 can flow into the condenser 3 through the lower sealing seat 9. The condenser 3 is used to cool the extracted solution.

[0024] In this embodiment, the gas supply path includes a first proportional valve 11 and a gas multi-channel diversion module 12. The gas multi-channel diversion module 12 has one inlet and six outlets. The inlet of the first proportional valve 11 is connected to an inlet pipe 13. The outlet of the first proportional valve 11 and the inlet of the gas multi-channel diversion module 12 are connected through a gas supply pipe 14. The six outlets of the gas multi-channel diversion module 12 are respectively connected to six upper three-way valves 5 pipelines.

[0025] In this embodiment, the liquid supply path includes a mixing valve 15, a high-pressure pump 16, a second pressure sensor 17, and a liquid multi-channel diversion module 18 connected in sequence via pipelines. The liquid multi-channel diversion module 18 has one inlet and six outlets. Its inlet is connected to the high-pressure pump 16, and its six outlets are respectively connected to six upper three-way valves 5 via pipelines. The mixing valve 15 has four reagent inlets, allowing four different reagents to be injected into it. The mixing valve 15 then mixes the different reagents. After mixing, the mixture is pumped into the liquid multi-channel diversion module 18 by the high-pressure pump 16. The second pressure sensor 17 detects whether the pressure value of each first pressure sensor 2 is normal.

[0026] In this embodiment, the concentration flow path includes a second proportional valve 19 and a nitrogen splitter block 20. The nitrogen splitter block 20 has an inlet and several outlets. The inlet of the second proportional valve 19 is connected to the inlet pipe 13 through a second pipe 21. The outlet of the second proportional valve 19 is connected to the inlet of the nitrogen splitter block 20 through a third pipe 22. The several outlets of the nitrogen splitter block 20 are respectively connected to several first pipes 1 through several fourth pipes 23.

[0027] In this embodiment, a one-way valve 24 is provided on any of the fourth pipes 23. The function of the one-way valve 24 here is to prevent the solvent in the first pipe 1 from flowing into the fourth pipe 23, and at the same time allow the gas in the fourth pipe 23 to enter the first pipe 1 through it, and finally enter the collection bottle 6.

[0028] In this embodiment, the liquid multi-channel diversion module 18 is also connected to an overpressure protection valve 25 via a pipeline. The function of the overpressure protection valve 25 is to release pressure when the pressure value in the liquid supply path exceeds a preset value.

[0029] In this embodiment, any collection bottle 6 is also connected to an exhaust pipe 26.

[0030] In this embodiment, the lower three-way valve 4 is also connected to a waste liquid collection block 27 via a pipeline. The solution extracted from each extraction branch can flow into the collection bottle 6 if needed, and into the waste liquid collection block 27 if not needed.

[0031] Working principle:

[0032] During extraction: In this embodiment, the mixing valve 15 can simultaneously input up to four different reagents. In actual use, different reagents are selected according to the situation and then injected into the mixing valve 15 for mixing. The reagents mixed by the mixing valve 15 are delivered to the liquid multi-channel diversion module 18 by the high-pressure pump 16. Here, the second pressure sensor 17 can determine the total pressure value and the pressure values ​​of each branch (the pressure values ​​of the six extraction branches). The mixed solution is diverted to six outlets by the liquid multi-channel diversion block, and then passes through six upper three-way valves 5, through each first pressure sensor 2, through the upper sealing seat 8, the extraction tube 10, the lower sealing seat 9, the condenser 3, and finally to the lower three-way valve 4.

[0033] For any extraction branch, during extraction, the lower three-way valve 4 is closed first, then the upper three-way valve 5 is switched to the solution inlet. The high-pressure pump 16 continuously pumps the solution from the mixing valve 15, filling the first pipeline 1, and then injecting it into the extraction tube 10. When the solvent in the first pipeline 1 is full, the solvent pressure in the first pipeline 1 begins to rise. During extraction in the extraction tube 10, the heating unit heats the extraction tube 10, and the solvent in the extraction tube 10 vaporizes due to the heat, causing the pressure to rise. When the required pressure value is reached, the upper three-way valve 5 closes, and at this time, under the influence of temperature, the sample begins to extract the reagent. After extraction, the lower three-way valve 4 opens, and the solvent has two destinations: one is to flow to the collection bottle 6, and the other is to flow to the waste liquid collection block 27.

[0034] When the reagent cannot be flushed out of the first pipeline 1 (no pressure difference between inside and outside), the upper three-way valve 5 switches to the gas inlet. Gas first enters the first proportional valve 11, which then allows the gas to enter the gas supply pipe 14 and the first pipeline 1 at a certain pressure. The gas, under pressure, flows through these pipelines and flushes out the solution. The function of the first proportional valve 11 is to control the pressure of the gas entering the first pipeline 1, making it easier to purge samples with high viscosity and thus solving the problem of incomplete solution discharge.

[0035] During concentration: After extraction through each extraction branch, the solvent flows into the corresponding collection bottle 6 via the lower three-way valve 4, at which point the collection bottle 6 contains a certain volume of solvent. The lower three-way valve 4 is then switched to the closed state, and the heating block 7 begins to heat the reagent in the collection bottle 6. When the set temperature is reached, the second proportional valve 19 begins to blow nitrogen into the collection bottle 6. In practice, aluminum foil is placed on the top of the collection bottle 6 to prevent the reagent inside from evaporating. The volatile gas generated in the collection bottle 6 is discharged through the gas exhaust pipe 26. After a period of time, the reagent in the collection bottle 6 is concentrated to the required volume, the heating block 7 stops heating, and the nitrogen blowing in the concentration flow path stops.

[0036] The above description is merely a preferred embodiment of this utility model. It should be understood that this utility model is not limited to the forms disclosed herein and should not be construed as excluding other embodiments. It can be used in various other combinations, modifications, and environments, and can be altered within the scope of the concept described herein through the above teachings or related technologies or knowledge. Modifications and variations made by those skilled in the art that do not depart from the spirit and scope of this utility model should be protected within the scope of the appended claims.

Claims

1. A flow path for a rapid solvent extraction apparatus integrating extraction and concentration, characterized in that: It includes an extraction flow path and a concentration flow path. The extraction flow path includes a gas supply flow path, a liquid supply flow path and several extraction branches. Each extraction branch includes a first pipeline (1) and a first pressure sensor (2), an extraction unit, a condenser (3) and a lower three-way valve (4) arranged sequentially on the first pipeline (1). The first end of the first pipeline (1) is connected to an upper three-way valve (5), and the tail end of the first pipeline (1) is connected to a collection bottle (6). The collection bottle (6) is arranged on a heating block (7). The liquid supply flow path and the gas supply flow path are both connected to the upper three-way valve (5) pipeline. One end of the concentration flow path is connected to the air inlet end of the gas supply flow path, and the other end is connected to the first pipeline (1). The connection point between the concentration flow path and the first pipeline (1) is located between the lower three-way valve (4) and the collection bottle (6).

2. The flow path of a rapid solvent extraction instrument integrating extraction and concentration as described in claim 1, characterized in that: The extraction unit includes an upper sealing seat (8), a heating unit, and a lower sealing seat (9) arranged in sequence. The heating unit is provided with an extraction tube (10) with both ends open. The upper sealing seat (8) and the lower sealing seat (9) are used to seal the top and bottom ends of the extraction tube (10), respectively. The liquid in the first pipeline (1) can flow into the extraction tube (10) through the upper sealing seat (8), and the liquid in the extraction tube (10) can flow into the condenser (3) through the lower sealing seat (9).

3. The flow path of a rapid solvent extraction apparatus integrating extraction and concentration according to claim 2, characterized in that: The gas supply path includes a first proportional valve (11) and a gas multi-channel diversion module (12). The gas multi-channel diversion module (12) has an inlet and several outlets. The inlet of the first proportional valve (11) is connected to an inlet pipe (13). The outlet of the first proportional valve (11) and the inlet of the gas multi-channel diversion module (12) are connected through a gas supply pipe (14). Several outlets of the gas multi-channel diversion module (12) are respectively connected to several upper three-way valves (5) pipelines.

4. The flow path of a rapid solvent extraction apparatus integrating extraction and concentration according to claim 2, characterized in that: The liquid supply path includes a mixing valve (15), a high-pressure pump (16), a second pressure sensor (17), and a liquid multi-channel diversion module (18) connected in sequence. Several outlets of the liquid multi-channel diversion module (18) are respectively connected to several of the upper three-way valves (5) in pipeline.

5. The flow path of a rapid solvent extraction apparatus integrating extraction and concentration according to claim 3, characterized in that: The concentration flow path includes a second proportional valve (19) and a nitrogen splitter block (20). The nitrogen splitter block (20) has an inlet and several outlets. The inlet of the second proportional valve (19) is connected to the inlet pipe (13) through a second pipeline (21). The outlet of the second proportional valve (19) is connected to the inlet of the nitrogen splitter block (20) through a third pipeline (22). Several outlets of the nitrogen splitter block (20) are respectively connected to several first pipelines (1) through several fourth pipelines (23).

6. The flow path of a rapid solvent extraction apparatus integrating extraction and concentration as described in claim 5, characterized in that: A check valve (24) is installed on any of the fourth pipelines (23).

7. The flow path of a rapid solvent extraction apparatus integrating extraction and concentration as described in claim 4, characterized in that: The liquid multi-channel diversion module (18) is also connected to an overpressure protection valve (25) via pipeline.

8. The flow path of a rapid solvent extraction apparatus integrating extraction and concentration as described in claim 5, characterized in that: The collection bottle (6) is also connected to an exhaust pipe (26).

9. The flow path of a rapid solvent extraction apparatus integrating extraction and concentration according to claim 2, characterized in that: The lower three-way valve (4) is also connected to a waste liquid collection block (27) via a pipeline.

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