Liquid raw material mixing device for heparin sodium production

Abstract

The utility model discloses a kind of liquid raw material mixing devices for heparin sodium production, including mixing chamber, fixed platform and stirring assembly, mixing chamber is set on fixed platform, stirring assembly is set on mixing chamber, the inside of mixing chamber is provided with scraper, scraper is provided with driving rod, driving rod is extended to the outside of mixing chamber after passing through mixing chamber from the end of scraper, the end of driving rod located outside mixing chamber is provided with fixed frame;The surface of fixed platform is provided with infusion assembly at the position of staggered with mixing chamber.The utility model is through setting infusion assembly and first flushing component, infusion assembly is conveyed flushing fluid into first flushing component by driving rod, then flushing fluid is sprayed by first flushing component to flush stirring assembly and scraper, make stirring assembly and scraper be cleaned thoroughly, solve the problem that heparin sodium raw material stirring chamber is not cleaned thoroughly by scraper in prior art and affect heparin sodium next time raw material mixing.

Description

Technical Field

[0001] This utility model relates to the technical field of heparin sodium production equipment, and in particular to a liquid raw material mixing device for heparin sodium production. Background Technology

[0002] Sodium heparin is a very important coagulant in the medical field. It mainly exerts its anticoagulant effect by enhancing the activity of antithrombin III and inhibiting the activity of coagulation factors IIa (thrombin) and Xa. In the production of sodium heparin, a mixing device is used to stir the liquid sodium heparin raw material. The mixing operation of the mixing device can ensure the high efficiency and safety of the mixing process of sodium heparin raw material.

[0003] A search revealed a Chinese patent, CN21743518U, entitled "A Raw Material Mixing Device for Heparin Sodium Production." Its background section states that "a raw material mixing device is needed in the production of heparin sodium; however, existing raw material mixing devices for heparin sodium production are inconvenient to clean internally and lack adjustable discharge angles, making collection difficult." The patent further explains that "through the cooperation of a second motor, a bevel gear set, a first connecting rod, a second connecting rod, a third connecting rod, and a moving block, the second motor is started. The output of the second motor drives the bevel gear set to rotate, which in turn drives the first connecting rod to rotate. The first connecting rod then moves the second connecting rod through a sliding groove..." The rod rotates along the shaft on the housing, while the second connecting rod drives the third connecting rod to rotate slightly and move downwards. The third connecting rod drives the moving block to move downwards, the moving block drives the frame to move, and the frame drives the scraper to move downwards. The scraper cleans the inner wall of the mixing chamber, solving the problem of inconvenient internal cleaning of the raw material mixing device for heparin sodium production. However, we found that in actual use, because heparin sodium adheres to the inner wall of the mixing chamber, it is difficult to clean it thoroughly by scraper alone. Some still adheres to the mixing chamber, and heparin sodium raw material remains on the mixing components and scraper in the mixing chamber, which will affect the mixing of heparin sodium raw material in the next batch.

[0004] Therefore, how to provide a liquid raw material mixing device for the production of heparin sodium is a problem that urgently needs to be solved by those skilled in the art. Utility Model Content

[0005] One objective of this invention is to provide a liquid raw material mixing device for heparin sodium production. This invention solves the problem in the prior art where the cleaning of the heparin sodium raw material mixing chamber by scraper is incomplete, thus affecting the mixing of the next batch of heparin sodium raw materials.

[0006] A liquid raw material mixing device for heparin sodium production according to an embodiment of the present invention includes a mixing chamber, a fixed platform, and a stirring assembly. The mixing chamber is disposed on the fixed platform, and the stirring assembly is disposed on the mixing chamber. A scraper is disposed inside the mixing chamber, and a driving rod is disposed on the scraper. The end of the driving rod away from the scraper passes through the mixing chamber and extends to the outside of the mixing chamber. A fixing frame is disposed at the end of the driving rod located outside the mixing chamber. An infusion assembly is disposed at a position offset from the mixing chamber on the surface of the fixed platform. One end of the infusion assembly is fixed to the fixing frame. A cavity is disposed inside the fixing frame and the driving rod. A first rinsing assembly is disposed at the end face of the driving rod located inside the mixing chamber.

[0007] The infusion assembly includes a storage tank for storing flushing fluid, a water pump, and an infusion tube. The storage tank is fixed on the surface of the fixed platform at a position offset from the stirring assembly. The water pump is located at the top of the storage tank. The inlet end of the water pump passes through the storage tank and extends into the interior of the storage tank. The infusion tube is located on the infusion end of the water pump. The end of the infusion tube away from the water pump is fixed to the side surface of the fixed frame and communicates with the cavity.

[0008] The first flushing assembly includes a first flushing annular tube, a first flushing nozzle, and a second flushing nozzle. The first flushing annular tube is fixed on the side of the drive rod near the scraper and away from the inner wall of the mixing chamber. The first flushing nozzle is disposed on the inner side of the first flushing annular tube, and the second flushing nozzle is disposed on the outer side of the first flushing annular tube.

[0009] The outlet of the second flushing nozzle faces the scraper.

[0010] The bottom of the first flushing annular pipe is provided with a second flushing assembly for flushing the inner wall of the mixing chamber.

[0011] The second flushing assembly includes a connecting pipe, a second flushing annular pipe, and a third flushing nozzle. The connecting pipe is fixed to the bottom of the first flushing annular pipe, the second flushing annular pipe is fixed to the end of the connecting pipe away from the first flushing annular pipe, and the third flushing nozzle is disposed on the side of the second flushing annular pipe and faces the direction of the mixing chamber.

[0012] The infusion tube is a flexible tube.

[0013] The beneficial effects of this utility model are:

[0014] By setting up an infusion assembly and a first flushing assembly, the infusion assembly delivers flushing fluid into the first flushing assembly via a drive rod. The flushing fluid is then sprayed out through the first flushing assembly to flush the mixing assembly and the scraper, ensuring that the mixing assembly and the scraper are thoroughly cleaned. This solves the problem in the prior art where the scraper does not thoroughly clean the mixing chamber of heparin sodium raw material, thus affecting the mixing of heparin sodium raw material in the next batch.

[0015] By setting up a second flushing component, which pre-flushes the mixing chamber wall before the scraper scrapes downwards, some easily washed-away materials are removed. Then, the scraper performs the scraping operation, which not only reduces the amount of heparin sodium material remaining on the scraper but also improves the scraping effect. This prevents the scraper from scraping away too much heparin sodium material at once, thus avoiding the problem of incomplete scraping. Attached Figure Description

[0016] The accompanying drawings are provided to further illustrate the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention, but do not constitute a limitation thereof. In the drawings:

[0017] Figure 1 This is a schematic diagram of the overall three-dimensional structure of a liquid raw material mixing device for the production of heparin sodium proposed in this utility model.

[0018] Figure 2 This is a cross-sectional three-dimensional structural diagram of the position of the first rinsing component in a liquid raw material mixing device for heparin sodium production proposed in this utility model.

[0019] Figure 3 This is a cross-sectional three-dimensional structural diagram showing the positions of the infusion component and the stirring component in a liquid raw material mixing device for heparin sodium production proposed in this utility model.

[0020] Figure 4 This is a cross-sectional three-dimensional structural diagram showing the positions of the first rinsing component and the second rinsing component in a liquid raw material mixing device for heparin sodium production proposed in this utility model.

[0021] The attached diagram shows: 1. Mixing chamber; 2. Fixed platform; 3. Stirring assembly; 4. Scraper; 5. Drive rod; 6. Fixture; 7. Cavity; 8. First flushing assembly; 9. Storage tank; 10. Water pump; 11. Infusion tube; 12. First flushing annular tube; 13. First flushing nozzle; 14. Second flushing nozzle; 15. Second flushing assembly; 16. Connecting pipe; 17. Second flushing annular tube; 18. Third flushing nozzle. Detailed Implementation

[0022] The present invention will now be described in further detail with reference to the accompanying drawings. These drawings are simplified schematic diagrams, illustrating only the basic structure of the present invention, and therefore only show the components relevant to the present invention.

[0023] Example 1

[0024] refer to Figure 1 , Figure 2 , Figure 3 and Figure 4The system includes a mixing chamber 1, a fixed platform 2, and a stirring assembly 3. The mixing chamber 1 is mounted on the fixed platform 2, and the stirring assembly 3 is mounted on the mixing chamber 1. The stirring assembly 3 is an existing assembly used to stir and mix the heparin sodium raw material in the mixing chamber 1. A scraper 4 is installed inside the mixing chamber 1, adhering to the inner wall of the mixing chamber 1. The scraper 4 moves along the inner wall of the mixing chamber 1 to effectively scrape and clean the heparin sodium raw material. Two driving rods 5 are installed on the scraper 4, ensuring balanced force when the scraper 4 moves. One end of the driving rod 5, away from the scraper 4, passes through the mixing chamber 1 and extends to the outside of the mixing chamber 1. A fixing frame 6 is installed at the end of the driving rod 5 located outside the mixing chamber 1. An infusion assembly is installed at a position offset from the mixing chamber 1 on the surface of the fixed platform 2. The infusion assembly includes a storage tank 9 for storing flushing fluid, a water pump 10, and an infusion tube 11. 9 is fixed on the surface of the fixed platform 2 at a position offset from the stirring assembly 3. The top of the storage tank 9 is provided with an opening for adding rinsing liquid. A cover is provided on the opening to cover the opening. In order to maintain the pressure inside the storage tank 9, no sealing operation is required when the cover is closed. The water pump 10 is located at the top of the storage tank 9. The liquid inlet end of the water pump 10 passes through the storage tank 9 and extends into the interior of the storage tank 9. The infusion pipe 11 is a flexible pipe that can deform. When the driving rod 5 and the fixed frame 6 move up and down, the infusion pipe 11 moves without affecting the liquid flow inside the infusion pipe 11. The infusion pipe 11 is located on the infusion end of the water pump 10. The end of the infusion pipe 11 away from the water pump 10 is fixed to the side surface of the fixed frame 6 and the infusion pipe 11 communicates with the cavity 7. When the scraper 4 is operated, the water pump 10 needs to be started first. The water pump 10 pumps the rinsing liquid in the storage tank 9 through the infusion pipe 11 into the cavity 7 of the fixed frame 6 and the driving rod 5.

[0025] refer to Figure 1 , Figure 2 , Figure 3 and Figure 4One end of the infusion assembly is fixed to the fixing frame 6. The fixing frame 6 and the drive rod 5 have a cavity 7 inside. A first flushing assembly 8 is located on one end face of the drive rod 5 inside the mixing chamber 1. The first flushing assembly 8 includes a first flushing annular tube 12, a first flushing nozzle 13, and a second flushing nozzle 14. The first flushing annular tube 12 is fixed to the drive rod 5 near the scraper 4 and away from the inner wall of the mixing chamber 1. The first flushing nozzle 13 is located inside the first flushing annular tube 12, and the second flushing nozzle 14 is located on the outer side of the first flushing annular tube 12. The outlet of the second flushing nozzle 14 faces the scraper 4. During operation, the flushing fluid inside the cavity 7 enters... The flushing liquid enters the first flushing annular pipe 12, and then is distributed to the first flushing nozzle 13 and the second flushing nozzle 14 through the first flushing annular pipe 12. The flushing liquid sprayed by the first flushing nozzle 13 reaches the surface of the stirring assembly 3 and flushes the stirring assembly 3. The flushing liquid sprayed by the second flushing nozzle 14 flushes the scraper 4. Since the number of the first flushing nozzle 13 and the second flushing nozzle 14 is greater than one, and the first flushing nozzle 13 and the second flushing nozzle 14 are arranged in a ring array with the center of the first flushing annular pipe 12 as the array center, this design makes the first flushing nozzle 13 and the second flushing nozzle 14 flush evenly and achieve the purpose of efficient flushing.

[0026] Example 2

[0027] refer to Figure 1 , Figure 2 , Figure 3 and Figure 4 In this embodiment, a second flushing assembly 15 for flushing the inner wall of the mixing chamber 1 is provided at the bottom of the first flushing annular pipe 12. The second flushing assembly 15 includes a connecting pipe 16, a second flushing annular pipe 17, and a third flushing nozzle 18. The connecting pipe 16 is fixed at the bottom of the first flushing annular pipe 12, and the second flushing annular pipe 17 is fixed at the end of the connecting pipe 16 away from the first flushing annular pipe 12. The third flushing nozzle 18 is disposed on the side of the second flushing annular pipe 17 and faces the inside of the mixing chamber 1. During operation, the flushing liquid in the first flushing annular pipe 12 enters the second flushing annular pipe 17 in the second flushing assembly 15 through the connecting pipe 16. Then, after the flushing liquid is diverted through the second flushing annular pipe 17, it is sprayed out through the third flushing nozzle 18 to flush the inner wall of the mixing chamber 1. In this way, the cleaning efficiency of the scraper 4 is improved by spraying the inner wall of the mixing chamber 1 once through the third flushing nozzle 18 before the scraper 4 scrapes down along the inner wall of the mixing chamber 1. It also avoids the scraper 4 from having too much heparin sodium material attached to it, which would affect the cleaning effect.

[0028] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A liquid raw material mixing device for the production of heparin sodium, characterized in that, It includes a mixing chamber (1), a fixed platform (2) and a stirring assembly (3). The mixing chamber (1) is set on the fixed platform (2), and the stirring assembly (3) is set on the mixing chamber (1). A scraper (4) is set inside the mixing chamber (1), and a driving rod (5) is set on the scraper (4). The end of the driving rod (5) away from the scraper (4) passes through the mixing chamber (1) and extends to the outside of the mixing chamber (1). A fixed frame (6) is set at the end of the driving rod (5) located outside the mixing chamber (1). An infusion assembly is provided at a position offset from the mixing chamber (1) on the surface of the fixed platform (2). One end of the infusion assembly is fixed on the fixed frame (6). A cavity (7) is provided inside the fixed frame (6) and the drive rod (5). A first flushing assembly (8) is provided on one end face of the drive rod (5) inside the mixing chamber (1). The first flushing assembly (8) includes a first flushing annular tube (12), a first flushing nozzle (13), and a second flushing nozzle (14). The first flushing annular tube (12) is fixed on the drive rod (5) near the scraper (4) and away from the inner wall of the mixing chamber (1). The first flushing nozzle (13) is located on the inner side of the first flushing annular tube (12), and the second flushing nozzle (14) is located on the outer side of the first flushing annular tube (12).

2. The liquid raw material mixing device for heparin sodium production according to claim 1, characterized in that, The infusion assembly includes a storage tank (9) for storing flushing fluid, a water pump (10) and an infusion tube (11). The storage tank (9) is fixed on the surface of the fixed platform (2) at a position offset from the stirring assembly (3). The water pump (10) is located at the top of the storage tank (9). The inlet end of the water pump (10) passes through the storage tank (9) and extends into the interior of the storage tank (9). The infusion tube (11) is located on the infusion end of the water pump (10). The end of the infusion tube (11) away from the water pump (10) is fixed to the side surface of the fixed frame (6) and the infusion tube (11) communicates with the cavity (7).

3. The liquid raw material mixing device for heparin sodium production according to claim 2, characterized in that, The outlet of the second flushing nozzle (14) faces the scraper (4).

4. The liquid raw material mixing device for heparin sodium production according to claim 3, characterized in that, The bottom of the first flushing annular pipe (12) is provided with a second flushing assembly (15) for flushing the inner wall of the mixing chamber (1).

5. A liquid raw material mixing device for heparin sodium production according to claim 4, characterized in that, The second flushing assembly (15) includes a connecting pipe (16), a second flushing annular pipe (17), and a third flushing nozzle (18). The connecting pipe (16) is fixed to the bottom of the first flushing annular pipe (12), the second flushing annular pipe (17) is fixed to the end of the connecting pipe (16) away from the first flushing annular pipe (12), and the third flushing nozzle (18) is disposed on the side of the second flushing annular pipe (17) and faces the inside of the mixing chamber (1).

6. A liquid raw material mixing device for heparin sodium production according to claim 5, characterized in that, The infusion tube (11) is a flexible tube.

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