Nanobody constant temperature shaker capable of fixing multiple types of containers
By designing a nano-antibody constant-temperature shaker that can fix multiple types of containers, and adopting an innovative structure of clamping and locking components, the problem of inconvenient container fixing in the prior art has been solved. This enables rapid fixing and reliable clamping of different types of containers, improving ease of use and reliability.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- SHANGCHUN BIOTECHNOLOGY (WUHAN) CO LTD
- Filing Date
- 2024-12-30
- Publication Date
- 2026-06-16
AI Technical Summary
Existing constant temperature shakers are inconvenient for fixing various types of nanobody storage containers, resulting in inconvenience in use.
A nanoantibody thermostatic shaker capable of securing various types of containers was designed. It employs two sets of clamping and locking components. The combination of clamping blocks and handwheels enables rapid securing of containers of different diameters, while the cooperation of springs and locking pins ensures the reliability of the clamping.
It enables rapid fixation and reliable clamping of different types of containers, improving the adaptability and reliability of the thermostatic shaker.
Smart Images

Figure CN224358313U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of constant temperature shaker technology, specifically a nano-antibody constant temperature shaker that can fix various types of containers. Background Technology
[0002] Nanobodies are widely used in the development of therapeutic antibody drugs, diagnostic reagents, affinity purification matrices, and scientific research. Nanobodies should be stored at 4°C or -20°C. Therefore, most nanobodies are stored in a constant temperature shaker. When using a constant temperature shaker, it is necessary to first select a clamp that matches the storage container containing the nanobodies, then fix the clamp to the shaking table of the constant temperature shaker, and then fix the storage container to the constant temperature shaker using the clamp. When there are many storage containers, they need to be fixed one by one, which makes the use of the constant temperature shaker inconvenient. To address the above issues, technological innovations are made based on the existing constant temperature shakers. Utility Model Content
[0003] The purpose of this invention is to provide a nanobody constant temperature shaker that can fix various types of containers, so as to solve the problems mentioned in the background art.
[0004] To achieve the above objectives, this utility model provides the following technical solution: a nano-antibody isothermal shaker capable of fixing various types of containers, comprising:
[0005] A constant-temperature shaker has two sets of clamping assemblies evenly placed on its shaking table. The two sets of clamping assemblies have identical structures and are placed side-by-side horizontally. A locking component is mounted on the top of each clamping assembly. Each clamping assembly includes a support frame, with support columns evenly distributed at the bottom. A set of guide grooves is formed on both the left and right sides of the inner sidewall of the support frame. A set of second clamping blocks is provided on both the front and rear sides of the inner sidewall of the support frame. Two sets of first clamping blocks are placed between the two sets of second clamping blocks. A set of second guide blocks is provided on both the left and right sides of each second clamping block. An internally threaded slider is provided on the left side of each first clamping block, and a first guide block is provided on the right side of each first clamping block. A bidirectional lead screw is screwed internally into each of the two sets of internally threaded sliders. The lead screw is rotatably mounted in a guide groove on the left side of the inner wall of the support frame. A through hole is provided on the front side of the support frame. A first handwheel is connected to the through hole on the front side of the bidirectional lead screw. The second guide block on the left side of the internal threaded slider and the second clamping block is slidably mounted in the guide groove on the left side of the inner wall of the support frame. The second guide block on the right side of the first guide block and the second clamping block is slidably mounted in the guide groove on the right side of the inner wall of the support frame. A set of mounting holes is provided on the opposite sides of the two sets of second clamping blocks. A bearing is installed in the mounting hole. A set of threaded holes is provided on both the front and rear sides of the support frame. A screw is screwed into the threaded hole. A second handwheel is provided on the outer side of the screw. The end of the screw away from the second handwheel is located on the inner ring of the bearing.
[0006] Preferably, the support columns are evenly arranged on the shaking table of the constant temperature shaker, and the support frame is located between the two sets of second handwheels.
[0007] Preferably, the locking assembly includes a concave pull plate, the bottom of which is uniformly provided with springs and locking posts, and the bottom of the locking posts is provided with anti-slip pads.
[0008] Preferably, the top of the support frame is provided with grooves evenly distributed, and the top of the support frame is provided with guide holes evenly distributed, the guide holes being connected to the through holes and threaded holes of the support frame.
[0009] Preferably, the concave pull plate is located at the top of the support frame, the spring is disposed in the groove of the support frame, the locking post is disposed in the guide hole of the support frame, and the bottom of the anti-slip pad is in contact with the top of the bidirectional lead screw and the screw rod.
[0010] Compared with the prior art, the beneficial effects of this utility model are as follows:
[0011] This invention allows for the quick fixation of two sets of containers by rotating a first handwheel to move two sets of first clamping blocks outwards and closer to two sets of second clamping blocks. When the two sets of containers are of different types, the second handwheel on the second clamping block on the outer side of the container with the smaller diameter can be rotated to move the second clamping block to slide, thereby making the second clamping block fit against the outer side of the container with the smaller diameter. This allows the device to fix two sets of containers of different types, thus improving the adaptability of the device.
[0012] After the container containing the nano-antibody is clamped and fixed by the first clamping block and the second clamping block, the concave pull plate is released. The spring rebound force drives the concave pull plate to move downward and reset. In this way, the locking pin drives the anti-slip pad to fit tightly with the screw and the double-acting screw. This can prevent the screw and the double-acting screw from rotating and causing the container to loosen when the constant temperature shaker shakes, thus ensuring the reliability of the device. Attached Figure Description
[0013] Figure 1 This is a schematic diagram of the structure of a nano-antibody constant temperature shaker that can fix multiple types of containers according to the present invention;
[0014] Figure 2 This is a schematic diagram of the clamping and locking components in a nano-antibody constant temperature shaker that can fix multiple types of containers according to the present invention.
[0015] Figure 3 This utility model Figure 2 First top sectional view;
[0016] Figure 4 This utility model Figure 2 The second top section view;
[0017] Figure 5 This utility model Figure 2 Front sectional view.
[0018] In the diagram: 1. Thermostatic shaking table; 11. Support column; 12. Support frame; 13. First clamping block; 131. Internal threaded slider; 132. Two-way lead screw; 133. First guide block; 14. Second clamping block; 141. Second guide block; 15. Concave pull plate; 151. Spring; 152. Locking column; 153. Anti-slip pad; 16. First handwheel; 17. Second handwheel; 18. Screw; 19. Bearing. Detailed Implementation
[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0020] Please see Figures 1-5 A nano-antibody constant temperature shaker that can fix multiple types of containers includes a constant temperature shaker 1. Two sets of clamping components are evenly placed on the shaking table of the constant temperature shaker 1. The two sets of clamping components have the same structure and are placed side by side in a horizontal direction. A locking component is placed on the top of the clamping components.
[0021] The clamping assembly includes a support frame 12, with support columns 11 evenly fixed at the bottom of the support frame 12. A set of guide grooves is provided on both the left and right sides of the inner sidewall of the support frame 12. A set of second clamping blocks 14 is slidably arranged on both the front and rear sides of the inner sidewall of the support frame 12. Two sets of first clamping blocks 13 are placed between the two sets of second clamping blocks 14. A set of second guide blocks 141 is fixedly arranged on both the left and right sides of the second clamping blocks 14. An internally threaded slider 131 is fixedly arranged on the left side of the first clamping block 13, and a first guide block 133 is fixedly arranged on the right side of the first clamping block 13. A bidirectional lead screw 13 is screwed into the interior of the two sets of internally threaded sliders 131. 2. The bidirectional lead screw 132 is rotatably mounted in a guide groove on the left side of the inner wall of the support frame 12. A through hole is provided on the front side of the support frame 12, and a first handwheel 16 is connected to the through hole on the front side of the bidirectional lead screw 132. The internal thread slider 131 and the second guide block 141 on the left side of the second clamping block 14 are both slidably mounted in the guide groove on the left side of the inner wall of the support frame 12. The first guide block 133 and the second guide block 141 on the right side of the second clamping block 14 are both slidably mounted in the guide groove on the right side of the inner wall of the support frame 12. A set of mounting holes is provided on the opposite sides of the two sets of second clamping blocks 14, and a bearing 19 is fixedly mounted in the mounting holes. A set of threaded holes is provided on both the front and rear sides of the support frame 12. A screw 18 is screwed into the threaded hole. A second handwheel 17 is fixedly installed on the outer side of the screw 18. The end of the screw 18 away from the second handwheel 17 is fixedly installed on the inner ring of the bearing 19. The support columns 11 are evenly arranged on the shaking table of the constant temperature shaker 1. The support frame 12 is located between the two sets of second handwheels 17. After opening the cover of the constant temperature shaker 1, the container containing the nano-antibody is placed between the first clamping block 13 and the second clamping block 14. By rotating the first handwheel 16, the bidirectional lead screw 132 is driven to rotate. The bidirectional lead screw 132 drives the two sets of internally threaded sliders 131 to move outward. The movement causes the two sets of first clamping blocks 13 to move outward and closer to the two sets of second clamping blocks 14 with the assistance of the first guide block 133. This allows for the quick fixation of the two sets of containers. When the two sets of containers are of different types, the second handwheel 17 on the second clamping block 14 on the outside of the container with the smaller diameter can be rotated to drive the screw 18 to rotate. The screw 18, through the bearing 19, causes the second clamping block 14 to slide with the assistance of the second guide block 141, so that the second clamping block 14 fits against the outside of the container with the smaller diameter. This allows the device to fix two sets of containers of different types, thereby improving the adaptability of the device.
[0022] The locking assembly includes a concave pull plate 15. Springs 151 and locking posts 152 are evenly fixedly disposed on the bottom of the concave pull plate 15. An anti-slip pad 153 is fixedly disposed on the bottom of the locking post 152. Grooves are evenly distributed on the top of the support frame 12, and guide holes are evenly distributed on the top of the support frame 12. The guide holes communicate with the through holes and threaded holes of the support frame 12. The concave pull plate 15 is located on the top of the support frame 12. Springs 151 are fixedly disposed within the grooves of the support frame 12. Locking posts 152 are slidably disposed within the guide holes of the support frame 12. The bottom of the anti-slip pad 153 is in contact with the top of the bidirectional lead screw 132 and the screw 18. Pulling the concave pull plate upwards... 15. The locking pin 152 causes the anti-slip pad 153 to separate from the screw 18 and the bidirectional lead screw 132. At this time, the screw 18 and the bidirectional lead screw 132 can be rotated. After the container containing the nano-antibody is clamped and fixed by the first clamping block 13 and the second clamping block 14, the concave pull plate 15 is released. At this time, the spring force 151 is used to drive the concave pull plate 15 to move downward and reset. In this way, the locking pin 152 causes the anti-slip pad 153 to fit tightly with the screw 18 and the bidirectional lead screw 132. This can prevent the screw 18 and the bidirectional lead screw 132 from rotating and causing the container to loosen when the constant temperature shaker 1 shakes, thus ensuring the reliability of the device.
[0023] Working principle: After opening the lid of the constant temperature shaker 1, place the container containing the nano-antibody between the first clamping block 13 and the second clamping block 14. Pull the concave pull plate 15 upwards, which, through the locking pin 152, causes the anti-slip pad 153 to separate from the screw 18 and the double-acting screw 132. By rotating the first handwheel 16, the double-acting screw 132 is rotated, which in turn causes the two sets of internal threaded sliders 131 to move outwards. This, in turn, causes the two sets of first clamping blocks 13 to move outwards and closer to the two sets of second clamping blocks 14 with the assistance of the first guide block 133. This quickly fixes the two sets of containers. When the two sets of containers are of different types, the second handwheel 17 on the second clamping block 14 on the outside of the container with the smaller diameter can be rotated to rotate the screw 18. The screw 18, through the bearing 19, causes the second clamping block 14 to slide with the assistance of the second guide block 141, thereby allowing the second clamping block 14 to fit against the outside of the container with a smaller diameter. This allows the device to fix two different types of containers, thus improving the adaptability of the device. After the container containing nano-antibodies is clamped and fixed by the first clamping block 13 and the second clamping block 14, the concave pull plate 15 is released. At this time, the spring 151's rebound force drives the concave pull plate 15 to move downward and reset. This causes the anti-slip pad 153 to fit tightly against the screw 18 and the bidirectional lead screw 132 through the locking pin 152. This prevents the screw 18 and the bidirectional lead screw 132 from rotating and causing the container to loosen when the constant temperature shaker 1 shakes, thus ensuring the reliability of the device.
Claims
1. A nanobody isothermal shaker capable of fixing various types of containers, characterized in that, include: A constant temperature shaker (1) has two sets of clamping components evenly placed on its shaking table. The two sets of clamping components have the same structure and are placed side by side in a horizontal direction. A locking component is placed on the top of each clamping component. Each clamping component includes a support frame (12). Support columns (11) are evenly arranged at the bottom of the support frame (12). A set of guide grooves is opened on both the left and right sides of the inner sidewall of the support frame (12). A set of second clamps is arranged on both the front and rear sides of the inner sidewall of the support frame (12). Two sets of first clamping blocks (13) are placed between the two sets of second clamping blocks (14). A set of second guide blocks (141) is provided on both the left and right sides of the second clamping blocks (14). An internal threaded slider (131) is provided on the left side of the first clamping block (13), and a first guide block (133) is provided on the right side of the first clamping block (13). A bidirectional screw (132) is screwed into the interior of the two sets of internal threaded sliders (131). The bidirectional screw (132) rotates. The support frame (12) is provided with a guide groove on the left side of the inner wall of the support frame (12). A through hole is provided on the front side of the support frame (12). The first handwheel (16) is connected to the through hole on the front side of the bidirectional lead screw (132). The internal thread slider (131) and the second guide block (141) on the left side of the second clamping block (14) are both slidably provided in the guide groove on the left side of the inner wall of the support frame (12). The first guide block (133) and the second guide block (141) on the right side of the second clamping block (14) are also provided. Both are slidably set in the guide groove opened on the right side of the inner wall of the support frame (12). Each of the two sets of second clamping blocks (14) has a set of mounting holes on the opposite side. A bearing (19) is set in the mounting hole. A set of threaded holes is opened through the front and rear sides of the support frame (12). A screw (18) is screwed into the threaded hole. A second handwheel (17) is set on the outside of the screw (18). The end of the screw (18) away from the second handwheel (17) is set in the inner ring of the bearing (19).
2. The nanobody isothermal shaker capable of fixing multiple types of containers according to claim 1, characterized in that: The support columns (11) are evenly arranged on the shaking table of the constant temperature shaker (1), and the support frame (12) is located between the two sets of second handwheels (17).
3. The nanobody isothermal shaker capable of fixing multiple types of containers according to claim 2, characterized in that: The locking assembly includes a concave pull plate (15), on the bottom of which springs (151) and locking posts (152) are evenly arranged, and on the bottom of the locking posts (152) are anti-slip pads (153).
4. The nanobody isothermal shaker capable of fixing multiple types of containers according to claim 3, characterized in that: The top of the support frame (12) is uniformly provided with grooves, and the top of the support frame (12) is uniformly provided with guide holes, which are connected to the through holes and threaded holes of the support frame (12).
5. A nanobody isothermal shaker capable of fixing multiple types of containers according to claim 4, characterized in that: The concave pull plate (15) is located at the top of the support frame (12), the spring (151) is set in the groove of the support frame (12), the locking post (152) is set in the guide hole of the support frame (12), and the bottom of the anti-slip pad (153) is in contact with the top of the bidirectional lead screw (132) and the screw (18).