A multi-stage fine filtration device for pharmaceutical powder formulations

Abstract

This utility model discloses a multi-stage fine filtration device for pharmaceutical powder preparations, relating to the field of pharmaceutical powder preparation fine filtration technology. It includes a tank, inside which is a multi-stage sieving assembly for fine filtration of pharmaceutical powder; the tank also includes a dispersing assembly to facilitate uniform fine filtration of the pharmaceutical powder. The rotational motion of the dispersing assembly drives the multi-stage sieving assembly to vibrate and sieve up and down. A feed pipe is fixedly connected to the top outer wall of the tank, and a support base is fixedly connected to the bottom outer wall of the tank. This utility model achieves gradual fine filtration of pharmaceutical powder from coarse to fine through the multi-stage sieving assembly to improve filtration accuracy. The dispersing assembly uniformly disperses the powder and drives the sieving assembly to vibrate, thereby improving sieving efficiency. Furthermore, the structure is rationally designed, combining practicality and stability.

Description

Technical Field

[0001] This utility model relates to the field of fine filtration technology for pharmaceutical powder preparations, and in particular to a multi-stage fine filtration device for pharmaceutical powder preparations. Background Technology

[0002] In the production of pharmaceutical powder formulations, the fine filtration process plays a decisive role in drug quality. With the development of the pharmaceutical industry, the requirements for indicators such as the purity and particle size distribution of drug powders are becoming increasingly stringent. Ensuring that the powder is free of impurities and has a precise particle size is essential to guaranteeing the efficacy and safety of the drugs.

[0003] Currently, traditional pharmaceutical powder filtration devices have the following shortcomings: some devices can only achieve simple single-stage filtration, failing to effectively remove impurities of different particle sizes, resulting in filtration precision that cannot meet the needs of modern pharmaceutical manufacturing; some existing technologies rely on only a single filter screen, making it difficult to perform fine classification and screening of powders. Therefore, there is an urgent need for a multi-stage pharmaceutical powder filtration device to solve the above problems. Utility Model Content

[0004] The purpose of this invention is to address the shortcomings of existing technologies by proposing a multi-stage fine filtration device for pharmaceutical powder preparations. Its advantages include: achieving progressive fine filtration of pharmaceutical powder from coarse to fine through multi-stage sieving components to improve filtration accuracy; uniformly dispersing the powder with the aid of a dispersing component and driving the sieving components to vibrate to enhance sieving efficiency; and a reasonable structural design that combines practicality and stability.

[0005] To achieve the above objectives, the present invention adopts the following technical solution: A multi-stage fine filtration device for pharmaceutical powder formulations includes a tank, the interior of which is provided with a multi-stage sieving assembly for fine filtration of pharmaceutical powder. The tank is equipped with a dispersion component that facilitates uniform and fine filtration of drug powder. The rotation of the dispersion component drives the multi-stage sieving component to vibrate and sieve up and down.

[0006] Through the above technical solutions, the multi-stage sieving component can perform progressive fine filtration of drug powder from coarse to fine, improving filtration accuracy. Meanwhile, the dispersing component can not only uniformly disperse the drug powder during rotation, but also drive the multi-stage sieving component to vibrate up and down, improving sieving efficiency. The three components work together to achieve highly efficient fine filtration of drug powder formulations.

[0007] Preferably, a feed pipe is fixedly connected to the top outer wall of the tank, and a support base is fixedly connected to the bottom outer wall of the tank.

[0008] Through the above technical solutions, the support base provides support to the tank, ensuring the stability of the tank during operation and preventing the tank from shifting or tipping over due to vibration or other factors.

[0009] Preferably, the multi-stage screening assembly includes an annular plate fixedly connected to the inner circumference of the tank body, a spring fixedly connected to the top outer wall of the annular plate, a filter screen hopper fixedly connected to the top of the spring, and multiple filter screen hoppers distributed at equal distances inside the tank body. The outer circumference of each filter screen hopper is in contact with the inner circumference of the tank body, and the filter screen hoppers are fixedly connected to each other by support columns.

[0010] Through the above technical solution, multiple equally spaced filter hoppers form a multi-stage sieving structure, which can gradually filter the drug powder. The outer circumference of the filter hopper is in contact with the inner circumference of the tank, which can prevent the powder from leaking out from the gaps. At the same time, the support column fixes the multiple filter hoppers into a whole, so that they can perform vibration sieving synchronously.

[0011] Preferably, the bottom of the multiple filter hoppers is fixedly connected to a first discharge pipe, a second discharge pipe, and a third discharge pipe, respectively. The second discharge pipe is sleeved outside the first discharge pipe, and the second discharge pipe is sleeved outside the second discharge pipe. A discharge trough is opened at the bottom of the tank, and the first discharge pipe, the second discharge pipe, and the third discharge pipe all pass through the inside of the discharge trough.

[0012] The above technical solution involves using the first, second, and third feed pipes to discharge drug powders of different particle sizes after being sieved by multiple filter screens.

[0013] Preferably, the outer circumferential walls of the first, second, and third feeding pipes are all fixedly connected to feeding hoppers, and the feeding hoppers are inclined.

[0014] The above technical solutions can guide the screened powder to be discharged smoothly, avoid the powder from accumulating at the pipe opening, and ensure the smoothness of the feeding process.

[0015] Preferably, the dispersing component includes a motor fixedly connected to the outer circumferential wall of the tank body, a second rotating column fixedly connected to the output end of the motor, a second helical gear fixedly connected to the outer circumferential wall of the second rotating column, a first helical gear meshing with the outer circumferential wall of the second helical gear, a first rotating column fixedly connected to the top outer wall of the first helical gear, and dispersing rods evenly spaced and circularly distributed fixedly connected to the outer circumferential wall of the first rotating column.

[0016] Through the above technical solution: the dispersing rod on the first rotating column can evenly disperse the falling drug powder as it rotates, avoiding powder accumulation and allowing the powder to enter the sieving stage more evenly.

[0017] Preferably, the interior of the tank is provided with a protective shell for protecting the first helical gear and the second helical gear. A diagonal rod is fixedly connected to the outer circumferential wall of the protective shell, and the other end of the diagonal rod is fixedly connected to the inner circumferential wall of the tank.

[0018] Through the above technical solutions, the protective shell can prevent the drug powder from contacting the first helical gear and the second helical gear, prevent the powder from adhering to the gear surface and causing the gears to jam, and play a role in protecting the gear set.

[0019] Preferably, a rotating seat is fixedly connected to the inner circumferential wall of the tank, and the first rotating column is rotatably connected to the rotating seat.

[0020] The above technical solutions provide support and limit the first rotating column, ensuring greater stability and reducing swaying during rotation.

[0021] Preferably, a fixed cylinder is fixedly connected to the outer circumference of the second rotating column, a swing rod is fixedly connected to the outer circumference of the fixed cylinder, and a pressing column is fixedly connected to one end of the swing rod.

[0022] Through the above technical solution: the pressing column will periodically press the filter screen bucket during rotation, and in conjunction with the elasticity of the spring, the filter screen bucket will vibrate up and down, preventing powder from clogging the filter screen and improving screening efficiency.

[0023] Preferably, the inner circumferential wall of the filter hopper is fixedly connected to a dispersing hopper, which facilitates the full passage of drug powder through the filter hopper for sieving. The dispersing hopper is mountain-shaped, and the outer circumferential wall of the dispersing hopper is provided with a discharge trough to facilitate the falling of drug powder.

[0024] Through the above technical solutions: the dispersing hopper is shaped like a mountain peak, which can guide the falling drug powder to all sides, avoiding the situation where the powder is concentrated in the center of the filter hopper and discharged from the pipeline without being filtered. The material leakage trough can make the powder fall evenly onto the surface of the filter screen in the filter hopper, ensuring that the powder fully contacts the filter screen for filtration.

[0025] The beneficial effects of this utility model are as follows: This invention utilizes a multi-stage sieving assembly, forming a multi-stage sieving structure from coarse to fine by using multiple equally spaced filter hoppers connected by support columns. This allows for gradual fine filtration of drug powders, significantly improving filtration accuracy and meeting the stringent fineness requirements of drug powder formulations. Simultaneously, the mountain-shaped dispersing hoppers within the filter hoppers guide the powder in all directions, and the discharge trough ensures the powder falls evenly onto the filter screen, guaranteeing thorough sieving and avoiding incomplete sieving caused by localized accumulation.

[0026] This invention achieves efficient screening by combining a dispersing component with a vibration drive structure. When the dispersing rod rotates under the drive of the motor, it can evenly disperse the falling powder, avoiding accumulation that affects efficiency and allowing the powder to contact the screening structure more evenly. Meanwhile, the periodic pressing of the pressing column, combined with the elasticity of the spring, causes the filter screen to vibrate up and down, effectively preventing powder from clogging the filter screen, accelerating the screening speed, improving the overall fine filtration efficiency, and solving the problems of easy clogging and low efficiency in traditional screening devices.

[0027] This utility model saves space and avoids mixing of materials of different specifications by nesting the first, second and third feeding pipes. The inclined feeding hopper facilitates material discharge, and the protective shell protects the gear set, preventing the gears from jamming due to the accumulation of powder on the surface, thus extending the service life of the equipment. The rotating seat ensures the stable rotation of the first rotating column, while the support seat ensures the overall stability of the tank, enabling the device to maintain a good working condition during long-term operation and improving the reliability and practicality of the equipment. Attached Figure Description

[0028] Figure 1 This is a front structural diagram of a multi-stage fine filtration device for pharmaceutical powder preparations proposed in this utility model; Figure 2 This is a schematic diagram of the overall semi-sectional structure of a multi-stage fine filtration device for pharmaceutical powder preparations proposed in this utility model; Figure 3 This utility model proposes a multi-stage fine filtration device for pharmaceutical powder formulations. Figure 2 Enlarged structural diagram at point A; Figure 4 This utility model proposes a multi-stage fine filtration device for pharmaceutical powder formulations. Figure 2 A magnified structural diagram at point B in the middle.

[0029] In the diagram: 1. Tank body; 2. Motor; 3. Feed pipe; 4. Discharge hopper; 5. First rotating column; 6. Rotating seat; 7. Dispersing rod; 8. Protective shell; 9. First helical gear; 10. Second helical gear; 11. Second rotating column; 12. Fixed cylinder; 13. Pressing column; 14. Swing rod; 15. Filter screen hopper; 16. Support column; 17. Dispersing hopper; 18. Leakage trough; 20. First discharge pipe; 21. Second discharge pipe; 22. Third discharge pipe; 23. Discharge trough; 24. Ring plate; 25. Spring. Detailed Implementation

[0030] The technical solution of this patent will be further described in detail below with reference to specific embodiments.

[0031] Reference Figures 1-4A multi-stage fine filtration device for pharmaceutical powder formulations includes a tank 1, the inside of which is provided with a multi-stage sieving component for fine filtration of pharmaceutical powder. The tank 1 is equipped with a dispersion component that facilitates uniform and fine filtration of drug powder. The rotation of the dispersion component drives the multi-stage sieving component to vibrate and sieve up and down. As the main structure of the entire device, the tank 1 provides installation and working space for the multi-stage sieving component and the dispersion component. The multi-stage sieving component can perform progressive fine filtration of drug powder from coarse to fine, improving filtration accuracy. During rotation, the dispersion component can both uniformly disperse the drug powder and drive the multi-stage sieving component to vibrate up and down, improving sieving efficiency. The three components work together to achieve efficient fine filtration of drug powder formulations.

[0032] To ensure the stability of the entire tank 1, refer to the appendix. Figure 1 The top outer wall of the tank 1 is fixedly connected to the feed pipe 3, and the bottom outer wall of the tank 1 is fixedly connected to the support base. The feed pipe 3 is used to transport the drug powder to be filtered into the tank 1 and is the channel for the powder to enter the device. The support base supports the tank 1, ensuring the stability of the tank 1 during operation and preventing the tank 1 from shifting or tipping over due to vibration or other factors.

[0033] To achieve multi-stage sieving and fine filtration of drug powders, refer to the appendix. Figures 2-4 The multi-stage screening assembly includes an annular plate 24 fixedly connected to the inner circumference of the tank 1. A spring 25 is fixedly connected to the top outer wall of the annular plate 24. A filter screen hopper 15 is fixedly connected to the top of the spring 25. Multiple filter screen hoppers 15 are evenly distributed inside the tank 1. The outer circumference of the filter screen hopper 15 contacts the inner circumference of the tank 1. The filter screen hoppers 15 are fixedly connected by support columns 16. The annular plate 24 provides a fixed support point for the spring 25. Spring 25 is elastic and deforms when subjected to external force. It can return to its original shape when the external force is removed, thereby driving the filter screen 15 to vibrate up and down. Multiple filter screens 15 distributed at equal distances form a multi-stage sieving structure, which can gradually filter the drug powder. The outer circumference of the filter screen 15 is in contact with the inner circumference of the tank 1, which can prevent the powder from leaking out from the gaps. At the same time, the support column 16 fixes multiple filter screens 15 into a whole, so that they can vibrate and sieve synchronously.

[0034] To facilitate the discharge of powder from tank 1, please refer to the appendix. Figures 2-4The bottom of multiple filter hoppers 15 is fixedly connected to a first discharge pipe 20, a second discharge pipe 21, and a third discharge pipe 22, respectively. The second discharge pipe 21 is sleeved outside the first discharge pipe 20, and the third discharge pipe 22 is sleeved outside the second discharge pipe 21. A discharge trough 23 is opened at the bottom of the tank body 1. The first discharge pipe 20, the second discharge pipe 21, and the third discharge pipe 22 all pass through the inside of the discharge trough 23. The first discharge pipe 20, the second discharge pipe 21, and the third discharge pipe 22 are used to discharge the drug powder of different particle sizes after being screened by multiple filter hoppers 15. The nested arrangement of the second discharge pipe 21 sleeved outside the first discharge pipe 20 and the third discharge pipe 22 sleeved outside the second discharge pipe 21 saves space and avoids mixing of powders of different particle sizes during the discharge process. The discharge trough 23 provides a channel for multiple discharge pipes to pass through the bottom of the tank body 1, which facilitates the discharge of powder from the tank body 1.

[0035] To prevent powder from accumulating at the nozzle and ensure smooth material feeding, please refer to the attached document. Figure 4 The outer circumference of the first discharge pipe 20, the second discharge pipe 21 and the third discharge pipe 22 are all fixedly connected to the discharge hopper 4. The discharge hopper 4 is set at an inclination so as to guide the sieved powder to be discharged smoothly.

[0036] To ensure the falling drug powder is evenly dispersed, preventing powder accumulation and allowing it to enter the sieving process more uniformly, refer to the appendix. Figures 2-3 The dispersion component includes a motor 2 fixedly connected to the outer circumference of the tank 1. A second rotating column 11 is fixedly connected to the output end of the motor 2. A second helical gear 10 is fixedly connected to the outer circumference of the second rotating column 11. A first helical gear 9 meshes with the outer circumference of the second helical gear 10. A first rotating column 5 is fixedly connected to the top outer wall of the first helical gear 9. Dispersion rods 7, evenly spaced and circularly distributed, are fixedly connected to the outer circumference of the first rotating column 5. The motor 2 provides power to the dispersion component, driving the second rotating column 11 to rotate. The second rotating column 11 drives the first rotating column 5 to rotate through the meshing transmission between the second helical gear 10 and the first helical gear 9. At the same time, the dispersion rods 7 on the first rotating column 5 rotate with it, which can evenly disperse the falling drug powder, avoid powder accumulation, and make the powder enter the sieving stage more evenly.

[0037] To prevent powder from adhering to the gear surface and causing gear jamming, please refer to the attached... Figure 2 The canister 1 is equipped with a protective shell 8 for protecting the first helical gear 9 and the second helical gear 10. A diagonal rod is fixedly connected to the outer circumferential wall of the protective shell 8, and the other end of the diagonal rod is fixedly connected to the inner circumferential wall of the canister 1. The protective shell 8 can prevent the drug powder from contacting the first helical gear 9 and the second helical gear 10, and prevent the powder from adhering to the gear surface and causing the gears to jam, thus protecting the gear set. At the same time, the diagonal rod fixes the protective shell 8 to the inner circumferential wall of the canister 1 to ensure the stability of the protective shell 8.

[0038] To ensure that the dispersing rod 7 can perform its dispersing function smoothly, refer to the attached document. Figure 3 A rotating seat 6 is fixedly connected to the inner circumference of the tank body 1. The first rotating column 5 is rotatably connected to the rotating seat 6. The rotating seat 6 is fixed to the inner circumference of the tank body 1, which supports and limits the first rotating column 5, ensuring that the first rotating column 5 is more stable and reduces shaking during rotation.

[0039] To prevent powder from clogging the filter screen and improve screening efficiency, please refer to the attached document. Figures 2-3 A fixed cylinder 12 is fixedly connected to the outer circumference of the second rotating column 11. A swing rod 14 is fixedly connected to the outer circumference of the fixed cylinder 12. A pressing column 13 is fixedly connected to one end of the swing rod 14. The fixed cylinder 12 rotates with the second rotating column 11, which drives the swing rod 14 and the pressing column 13 to rotate. At the same time, the pressing column 13 will periodically press the filter screen hopper 15 during the rotation process. With the elasticity of the spring 25, the filter screen hopper 15 will vibrate up and down to prevent powder from clogging the filter screen and improve the screening efficiency.

[0040] To ensure that the powder fully contacts the filter screen for filtration, please refer to the attached document. Figure 2 The inner circumference of the filter hopper 15 is fixedly connected to a dispersing hopper 17, which facilitates the full passage of drug powder through the filter hopper 15 for sieving. The dispersing hopper 17 is mountain-shaped, and the outer circumference of the dispersing hopper 17 is provided with a material leakage groove 18 to facilitate the falling of drug powder. The mountain-shaped dispersing hopper 17 can guide the falling drug powder to all sides, avoiding the situation where the powder is concentrated in the center of the filter hopper 15 and discharged from the pipe without being filtered. The material leakage groove 18 can make the powder fall evenly onto the filter screen surface of the filter hopper 15, ensuring that the powder fully contacts the filter screen for filtration.

[0041] Working principle: After the drug powder enters from the feed pipe 3 at the top of the tank 1, it is first dispersed by the dispersion component. During this process, the motor 2 drives the second rotating column 11 to rotate. Through the meshing transmission of the second helical gear 10 and the first helical gear 9, the first rotating column 5 is driven to rotate, causing the dispersion rod 7 on the first rotating column 5 to rotate, so that the falling powder is evenly dispersed, avoiding the accumulation of powder and affecting the screening efficiency. At the same time, this dispersion method allows the powder to contact the subsequent screening structure more evenly, improving the fine filtration effect. While the dispersing component is working, the fixed cylinder 12 on the second rotating column 11 drives the swing rod 14 and the pressing column 13 to rotate. The pressing column 13 periodically applies pressure to the filter screen hopper 15. Combined with the elastic action of the spring 25 on the ring plate 24, the multiple filter screen hoppers 15 connected by the support column 16 vibrate up and down. This vibration design can effectively prevent powder from clogging the filter screen and speed up the screening speed. The multiple filter screen hoppers 15 distributed at equal distances form a multi-stage screening structure due to the different mesh sizes, which can gradually finely filter the powder from coarse to fine, greatly improving the filtration accuracy. The mountain-shaped dispersing hopper 17 in each filter hopper 15 guides the powder to all sides, and then it falls evenly onto the filter screen through the discharge trough 18, further ensuring the sieving is sufficient. The powder after each stage of screening is discharged through the corresponding first discharge pipe 20, second discharge pipe 21, third discharge pipe 22 (the three are nested, which not only saves space but also effectively avoids the mixing of materials of different specifications) and the inclined discharge hopper 4. Throughout the process, the protective shell 8 protects the gear set, the rotating seat 6 ensures the stable rotation of the first rotating column 5, and the support seat ensures the overall stability of the tank 1, thus achieving efficient, accurate, and uniform multi-stage fine filtration of drug powder.

[0042] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A multi-stage fine filtration device for pharmaceutical powder formulations, comprising a tank (1), characterized in that, The interior of the tank (1) is equipped with a multi-stage sieving assembly for fine filtration of drug powder; The tank (1) is equipped with a dispersion component that facilitates uniform and fine filtration of drug powder. The rotation of the dispersion component drives the multi-stage sieving component to vibrate and sieve up and down.

2. The multi-stage fine filtration device for pharmaceutical powder formulations according to claim 1, characterized in that, The top outer wall of the tank (1) is fixedly connected to a feed pipe (3), and the bottom outer wall of the tank (1) is fixedly connected to a support base.

3. The multi-stage fine filtration device for pharmaceutical powder formulations according to claim 2, characterized in that, The multi-stage screening assembly includes an annular plate (24) fixedly connected to the inner circumference of the tank (1). A spring (25) is fixedly connected to the top outer wall of the annular plate (24). A filter screen hopper (15) is fixedly connected to the top of the spring (25). There are multiple filter screen hoppers (15), which are evenly distributed inside the tank (1). The outer circumference of the filter screen hopper (15) is in contact with the inner circumference of the tank (1). The filter screen hoppers (15) are fixedly connected to each other by a support column (16).

4. The multi-stage fine filtration device for pharmaceutical powder formulations according to claim 3, characterized in that, The bottom of multiple filter hoppers (15) is fixedly connected to a first discharge pipe (20), a second discharge pipe (21), and a third discharge pipe (22). The second discharge pipe (21) is sleeved outside the first discharge pipe (20), and the second discharge pipe (21) is sleeved outside the second discharge pipe (21). The bottom of the tank body (1) is provided with a discharge trough (23). The first discharge pipe (20), the second discharge pipe (21), and the third discharge pipe (22) all pass through the inside of the discharge trough (23).

5. The multi-stage fine filtration device for pharmaceutical powder formulations according to claim 4, characterized in that, The outer circumferential walls of the first discharge pipe (20), the second discharge pipe (21) and the third discharge pipe (22) are all fixedly connected with discharge hoppers (4), and the discharge hoppers (4) are inclined.

6. The multi-stage fine filtration device for pharmaceutical powder formulations according to claim 5, characterized in that, The dispersing assembly includes a motor (2) fixedly connected to the outer circumference of the tank (1). The output end of the motor (2) is fixedly connected to a second rotating column (11). The outer circumference of the second rotating column (11) is fixedly connected to a second helical gear (10). The outer circumference of the second helical gear (10) meshes with a first helical gear (9). The top outer wall of the first helical gear (9) is fixedly connected to a first rotating column (5). The outer circumference of the first rotating column (5) is fixedly connected to dispersing rods (7) that are evenly spaced and distributed in a circular pattern.

7. The multi-stage fine filtration device for pharmaceutical powder formulations according to claim 6, characterized in that, The tank (1) is provided with a protective shell (8) for protecting the first helical gear (9) and the second helical gear (10). The outer circumferential wall of the protective shell (8) is fixedly connected with a diagonal rod, and the other end of the diagonal rod is fixedly connected to the inner circumferential wall of the tank (1).

8. The multi-stage fine filtration device for pharmaceutical powder formulations according to claim 7, characterized in that, A rotating seat (6) is fixedly connected to the inner circumference of the tank (1), and the first rotating column (5) is rotatably connected to the rotating seat (6).

9. A multi-stage fine filtration device for pharmaceutical powder formulations according to claim 8, characterized in that, A fixed cylinder (12) is fixedly connected to the outer circumference of the second rotating column (11), and a swing rod (14) is fixedly connected to the outer circumference of the fixed cylinder (12), and a pressing column (13) is fixedly connected to one end of the swing rod (14).

10. A multi-stage fine filtration device for pharmaceutical powder formulations according to claim 9, characterized in that, The inner circumference of the filter hopper (15) is fixedly connected to a dispersing hopper (17) that facilitates the full passage of drug powder through the filter hopper (15) for sieving. The dispersing hopper (17) is mountain-shaped, and the outer circumference of the dispersing hopper (17) is provided with a discharge trough (18) that facilitates the falling of drug powder.

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