REDOX-LABELED OLIGONUCLEOTIDE PROBES AND THEIR USE
DE602017088401T2Active Publication Date: 2025-03-19ABBOTT DIAGNOSTICS SCARBOROUGH INC
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Patent Information
- Application Number
- DE602017088401
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2016-02-26
- Filing Date
- 2017-02-24
- Publication Date
- 2025-03-19
- Estimated Expiration
- 2037-02-24
AI Technical Summary
Technical Problem
Current methods for detecting trace levels of target nucleic acids are not sufficiently sensitive, accurate, or reproducible for point-of-care testing and rapid diagnostics.
Method used
Development of oligonucleotide probes with modified residues conjugated to redox moieties and a 3' blocking group, which are used in conjunction with nucleic acid amplification methods and nucleases for electrochemical detection of target nucleic acid sequences.
Benefits of technology
The described approach provides a sensitive, accurate, and reproducible platform for detecting and quantifying target nucleic acid sequences, enabling rapid and effective diagnostics.
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