AUTOMATIC SAMPLER AND LIQUID ROMATOGRE
Patent Information
- Application Number
- DE602017088599
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- Filing Date
- 2017-07-04
- Publication Date
- 2025-03-26
- Estimated Expiration
- 2037-07-04
AI Technical Summary
The existing autosampler technologies face challenges in suppressing pressure fluctuations and ensuring reproducibility during the switching of the injection valve from the sample filling state to the sample injection state, leading to pressure shocks that affect the analysis results and column life, particularly in high-pressure supercritical fluid chromatography.
The autosampler employs a staged switching mechanism where the injection valve transitions from the sample filling state to an intermediate state and then to the sample injection state, ensuring one end of the sample loop is always connected to the liquid delivery channel and analysis channel before the other, and includes a control mechanism to manage the rotor's drive speed and pressure recovery, thereby stabilizing the flow rate and composition of the mobile phase.
This staged approach effectively suppresses pressure fluctuations, improves analysis reproducibility, and extends the life of the analysis column by ensuring consistent pressure and flow conditions during sample injection.