Production of microneedles for transdermal drug delivery by dynamic light processing

EP4539918A4Pending Publication Date: 2026-06-03KAZLI CESME DERI UERUENLERI ARASTIRMA GELISTIRMESANAYI & TICARET LTD SIRKETI

Patent Information

Authority / Receiving Office
EP · EP
Patent Type
Applications
Current Assignee / Owner
KAZLI CESME DERI UERUENLERI ARASTIRMA GELISTIRMESANAYI & TICARET LTD SIRKETI
Filing Date
2023-06-16
Publication Date
2026-06-03

AI Technical Summary

Technical Problem

Conventional methods for producing microneedle patches for transdermal drug delivery are labor-intensive, costly, and limited in producing microneedles with desired size and geometry, lacking the efficiency and accessibility required for fast and low-cost production.

Method used

The use of vat photopolymerization 3D printing techniques, specifically DLP, with Gelatin Methacrylate (GelMA) or a mixture of GelMA and Keratin Methacrylate (KerMA) or other methacrylated polymers, allowing for the design and production of hydrogel microneedles with precise geometry and high resolution, enabling rapid, cost-effective, and biocompatible microneedle patch manufacturing.

Benefits of technology

This method enables the production of hydrogel microneedles with high mechanical strength, adjustable drug release rates, and enhanced bioavailability, overcoming the limitations of conventional methods by providing a fast, easy, and low-cost solution for transdermal drug delivery with improved microneedle properties and patient convenience.

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Abstract

The invention relates to a method of manufacturing microneedle patches for transdermal drug delivery using dynamic light processing (DLP) technique using Gelatin Methacrylate (GelMA) or a mixture of Gelatin Methacrylate (GelMA) + Keratin Methacrylate (KerMA) or a blend with different methacrylated natural or synthetic polymers.
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