Methods for labeling eukaryotic cells from multicellular organisms and treating and / or diagnosing cancer using modified monosaccharide compounds - Patents.com
By developing modified monosaccharide compounds and combining these compounds with eukaryotic cells using click chemistry reactions, the cytotoxicity and lack of selectivity problems of carbohydrate/monosaccharide click chemistry methods in the prior art are solved, and efficient labeling and detection of cancer cells is achieved.
JP7653360B2Active Publication Date: 2025-03-28ダイアミデックス
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Patent Information
- Application Number
- JP2021549192
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2019-02-20
- Filing Date
- 2020-02-20
- Publication Date
- 2025-03-28
- Estimated Expiration
- 2040-02-20
AI Technical Summary
Technical Problem
In the prior art, carbohydrate/monosaccharide click chemical methods have cytotoxicity and lack selectivity for specific cells, especially for cancer cells.
Method used
A modified monosaccharide compound was developed to bind these compounds to eukaryotic cells through click chemical reactions, leveraging the specific properties of these compounds to show higher accumulation and binding efficiency in cancer cells.
Benefits of technology
The efficient labeling and detection of eukaryotic cells, especially cancer cells, provides a potential method for identification, isolation and treatment of cancer cells while avoiding cytotoxic problems.
✦ Generated by Eureka AI based on patent content.
Abstract
The present invention relates to modified monosaccharide compounds embodied in methods for labeling and / or detecting eukaryotic cells from multicellular organisms. The present invention also relates to such modified monosaccharide compounds embodied in methods for identifying or isolating cancer cells, diagnosing cancer, or for cell therapy.
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