Emulsifier composition for personal care formulations

Abstract

An emulsifier composition useful for preparing personal care formulations comprising microcrystalline cellulose, at least one biogum of microbial origin, and optionally at least one cellulose ether or derivative thereof. The emulsifier composition has beneficial effects on the stability, rheology, and consumer acceptability of the formulation. The invention extends to emulsions and personal care formulations comprising the emulsifier composition, as well as methods for preparing them. The invention also extends to the use of the emulsifier composition to stabilize emulsions comprising an oil phase and an aqueous phase.

Description

Technical Field

[0001] The present invention relates to an emulsifier composition suitable for use in the preparation of personal care formulations comprising an aqueous phase and an oil phase. In particular, the emulsifier composition can be used for formulating personal care formulations comprising emulsions such as skin care and hair care preparations. The emulsifier composition has beneficial effects on the stability, rheology, and consumer acceptability of the formulations. The present invention extends to emulsions and personal care formulations comprising the emulsifier composition, and methods for preparing them. The present invention also extends to the use of an emulsifier composition for stabilizing emulsions comprising an oil phase and an aqueous phase.

Background Art

[0002] Emulsions are one of the most common types of formulations used in cosmetics / personal care formulations. An emulsion is a heterogeneous system that is a mixture of two or more liquids that do not normally mix, that is, it is a mixture of two or more liquids that are immiscible or have limited miscibility. One of the liquids is distributed in the form of fine droplets in the other liquid. These droplets form the dispersed phase in the other liquid. The other liquid is called the continuous phase.

[0003] Emulsions include oil-in-water (O / W) or water-in-oil (W / O) emulsions. An oil-in-water (O / W) emulsion has water as the continuous phase and oil as the dispersed phase. A water-in-oil (W / O) emulsion has oil as the continuous phase and water as the dispersed phase.

[0004] Emulsions can act as vehicles to provide the skin with large amounts of lipids and lipid-soluble components, making the skin feel pleasant and offering advantages such as smoothness, softness, and / or moisturizing. However, emulsions are thermodynamically unstable systems and require stabilization, such as surfactants or polymers, to prevent phase separation over long periods. However, most stabilizing components are synthetic or surfactant molecules and can therefore disrupt the skin barrier. Furthermore, there is growing interest in the use of biodegradable and environmentally friendly ingredients in consumer products, especially personal care products.

[0005] The use of biopolymers in the personal care industry is well known. For example, natural polysaccharides can be used as rheological modifiers to adjust the viscosity of formulations.

[0006] Cellulose is the main component of the primary cell walls of green plants and some algae, and is the most abundant natural polymer in the world. It is widely used, for example, in the preparation of paper, food, pharmaceuticals, and cosmetics. Cellulose is a polysaccharide consisting of linear chains of hundreds to thousands of glucose units.

[0007] Cellulose has four different forms depending on its source and processing. Naturally occurring cellulose is known as cellulose I and is found in the cell walls of most plants. Cellulose II is used in textiles and can be obtained by heating natural cellulose in the presence of a strong alkali. Cellulose III and cellulose IV are less common and usually exist in combination with types I and II. Cellulose III is amorphous and can be obtained by treating cellulose I or cellulose II with ammonia or amines. Cellulose IV can be obtained by treating cellulose III with glycerol at high temperatures. When cellulose contains both crystalline and amorphous domains, it is known as microfibrillated cellulose (MFC) and is sometimes called nanofibrillated cellulose (NFC). The amorphous domains can be removed by using different processes such as reactive extrusion, enzymatic reactions, mechanical grinding, sonication, steam explosion, and acid hydrolysis with mineral acids such as sulfuric acid, hydrochloric acid, or hydrobromic acid. When this amorphous domain is removed, the product has properties different from those of natural cellulose and microcrystalline cellulose (MCC) (also known as nanocrystalline cellulose (NCC)).

[0008] MCC is well-known in the cosmetics and pharmaceutical industries. It is commonly used as an aqueous thickener, stabilizer, abrasive, absorbent, anti-caking agent, binder, or filler. MCC has also been proposed as an emulsion stabilizer in emulsions stabilized by solid microparticles [Fukisawa et al. "Nanocellulose-stabilized Pickering emulsions and their applications" Science and Technology of Advanced Materials, 2017 vol.18, no.1, 959-971]. This type of emulsion is called a Pickering emulsion. Nevertheless, MCC alone as an emulsion stabilizer has several drawbacks. For example, high shear forces are required, applied using sonication or microfluidization, to reduce the size of the oil droplets necessary to obtain a stable emulsion. In emulsions, the size of the oil droplets is a crucial factor in emulsion stability; smaller particle sizes result in better stability. Furthermore, high concentrations of MCC are required.

[0009] Kalashivikova et al. have disclosed Pickering emulsions stabilized by bacterial cellulose nanocrystals (BCN) [Kalashivikova et al. "New Pickering Emulsions Stabilized by Bacterial Cellulose Nanocrystals" (2011) Langmuir, 27, 2471-7479]. Bacterial cellulose nanocrystals are prepared by hydrochloric acid hydrolysis of bacterial cellulose. Kalashivikova et al. disclose a Pickering emulsion formulated in a 30 / 70 ratio (O / W) using a 5 g / L suspension of BCN in the aqueous phase. The application of shear using sonication is required, which makes scaling up this process extremely difficult. Furthermore, at BCN concentrations below 2 g / L, the oil and aqueous phases separate, and coalescence occurs due to compression during the centrifugation process. Therefore, high concentrations of BCN are required.

[0010] Capron et al. found that a sonication process is also required to stabilize Pickering 10 / 90 O / W emulsions containing cellulose nanocrystals and NaCl [Capron et al. "Surfactant-Free High Internal Phase Emulsions Stabilized by Cellulose Nanocrystals" (2013), Biomacromolecules, 14, 291-296]. Cellulose nanocrystals are obtained from cotton fibers by acid hydrolysis with sulfuric acid.

[0011] MCC is also attracting attention as an intermediate material for generating cellulose nanocrystals (CNCs) by microfluidization, and cellulose nanocrystals are modified with sodium carboxymethylcellulose (CNCC) to prepare redispersible camellia oil pickering emulsion powder (CO-PEP) [J.Xie, et al. "Redispersible Pickering emulsion powder stabilized by nanocrystalline cellulose combining with cellulosic derivatives" (2019) Carbohydrate Polymers, 213, 128-137].

[0012] Oza et al. have disclosed the use of Avicel RC591 MCC in 1:4 O / W emulsions [Oza et al. "Microcrystalline cellulose stabilized emulsions" (1986) J. Dispersion Science and Technology, 7(5), 533-561]. However, at an MMC concentration of 0.5% (w / w), oil droplets coalesce (as a result of insufficient Avicel in the system). Therefore, higher concentrations of MCC, such as 1% (w / w) or higher, are required. High concentrations of cellulose can result in high residue levels on the skin, which can lead to unpleasant sensory effects due to the balling up of the residue. Furthermore, MCC has poor compatibility with conventional surfactants such as Tween® 80. For these reasons, MCC is not entirely satisfactory as an emulsifying stabilizer.

[0013] German Patent Application Publication No. 10351859(A1) provides a preparation for use with an insect repellent containing an O / W emulsion containing MCC and xanthan gum. German Patent Application Publication No. 10351859(A1) discloses that the concentration of MCC in the preparation is 0.1 to 5% by weight based on the total weight of the preparation. German Patent Application Publication No. 10351859(A1) discloses that the concentration of xanthan gum in the preparation is 0.05 to 2.5% by weight based on the total weight of the preparation. German Patent Application Publication No. 10351859(A1) discloses an insect repellent in oil form at a concentration of 2 to 60% by weight based on the total weight of the preparation.

[0014] Other polysaccharides besides cellulose have also been proposed as coemulsifiers in surfactant systems.

[0015] Xu et al. have disclosed the effect of diutan microbial polysaccharide on the stability and rheological properties of oil-in-water nanoemulsions formed with a blend of Span®20-Tween®20 [Xu et al, "Effect of diutan microbial polysaccharide on the stability of O / W nanoemulsions formed with a blend of Span20Tween20", Journal of Dispersion Science and Technology, 2018, Vol.39, No.11, 1644-1654]. All nanoemulsions prepared using diutan gum (concentrations ranging from 70 to 700 mg L-1 (0.007 to 0.07%, w / w)) were more stable after 30 days and showed no apparent creaming. As the emulsifier content increases from 6.0% to 10%, the polydispersity index (PDI) obtained in the diameter distribution measurement of nanoemulsions increases, meaning that the droplet diameters of the nanoemulsions become closer together. However, the amount of surfactant required is high (i.e., at least 6%, w / w), and the maximum amount of water in the emulsion is 80% (w / w). High amounts of surfactant affect the skin barrier function and have harmful environmental impacts. In the food industry, diutan gum has also been proposed as a stabilizer for lemongrass essential oil emulsions containing Appyclean 6552 as a surfactant [Santos et al. "A comparison of microfluidization and sonication to obtain lemongrass submicron emulsions. Effect of diutan gum concentration as stabilizer" (2019). LWT-Food Science and Technology 114]. The emulsion provided contains 5% (w / w) oil, 0.5% (w / w) Applyclean 6652 (tension-active surfactant), and 0.2% (w / w) diutan gum, and is prepared by using high-energy methods such as sonication or microfluidization. The emulsion system requires a surfactant (i.e., a tension-active substance) and is therefore a different emulsion system from Pickering emulsions. Furthermore, there is no disclosure for stabilizing O / W emulsions with high concentrations of oil. Therefore, there is a need to find a new emulsion system that is stable and suitable for use in personal care formulations. There is a need to provide an alternative to conventional emulsifiers used in personal care formulations. There is a need to find a new emulsion system that exhibits improved stability over longer periods than other known emulsion systems. There is also a need to provide a naturally derived emulsifier. The present invention aims to satisfy some or all of these needs and solve some or all of the problems identified above. [Prior art documents] [Patent Documents]

[0016] [Patent Document 1] German Patent Application Publication No. 10351859 [Non-patent literature]

[0017] [Non-Patent Document 1] Fukisawa et al.”Nanocellulose-stabilized Pickering emulsions and their applications”Science and Technology of Advanced Materials,2017 vol.18,no.1,959-971 [Non-Patent Document 2] "New Pickering Emulsions Stabilized by Bacterial Cellulose Nanocrystals" (2011) Langmuir, 27, 2471-7479 [Non-Patent Document 3] "Surfactant-Free High Internal Phase Emulsions Stabilized by Cellulose Nanocrystals" (2013), Biomacromolecules, 14, 291-296 [Non-Patent Document 4] J.Xie, et al. “Redispersible Pickering emulsion powder stabilized by nanocrystalline cellulose combining with cellulosic derivatives” (2019) Carbohydrate Polymers, 213, 128-137 [Non-Patent Document 5] "Microcrystalline cellulose stabilized emulsions" (1986) J.Dispersion Science and Technology,7(5),533-561 [Non-Patent Document 6] Santos et al「A comparison of microfluidization and sonication to obtain lemongrass submicron emulsions. Effect of diutan gum concentration as stabilizer」(2019). LWT - Food Science and Technology 114

Summary of the Invention

Means for Solving the Problems

[0018] The present invention provides a) microcrystalline cellulose, and b) at least one biogum of microbial origin, and optionally c) at least one cellulose ether or its derivative, and provides an emulsifier composition containing the same.

[0019] Preferably, the emulsifier composition contains about 20 to about 90% by weight of microcrystalline cellulose, about 10 to about 80% by weight of at least one biogum produced by microbial fermentation, and about 0 to about 20% by weight of at least one cellulose ether or its derivative. The weight percentages are based on the total weight of the composition. It has been found that the emulsifier composition of the present invention can be used to provide very stable oil - in - water and water - in - oil emulsions. The high stability is considered to be due to the synergistic effect resulting from the combination of microcrystalline cellulose, at least one biogum, and, if present, at least one cellulose ether derivative. Furthermore, the emulsifier composition of the present invention has the advantages of low irritation to the skin and containing natural ingredients. The emulsifier composition of the present invention can be used to produce emulsions that can be used particularly in personal care formulations.

[0020] Therefore, in another aspect, the present invention provides i) an aqueous phase, and ii) an oil phase, and iii) providing an emulsion or a personal care formulation comprising the emulsifier composition of the present invention.

[0021] In another aspect, the present invention provides a method for preparing an emulsion or a personal care formulation comprising an oil phase and an aqueous phase, the method comprising the step of mixing the emulsifier composition of the present invention with the oil phase and the aqueous phase. The method for preparing an emulsion or a personal care formulation i) dispersing the emulsifier composition of the present invention in the aqueous phase; ii) stirring the oil phase into the aqueous phase to form an emulsion; and iii) adjusting the pH of the emulsion to less than 7.

[0022] In another aspect, the present invention provides a method for stabilizing an emulsion comprising an oil phase and an aqueous phase, the method comprising the step of mixing the emulsifier composition of the first aspect of the present invention with the oil phase and the aqueous phase. The emulsion can be a personal care formulation as described above.

[0023] In a further aspect, the present invention provides the use of the emulsifier composition of the first aspect of the present invention for stabilizing an emulsion comprising an oil phase and an aqueous phase. The emulsion can be a personal care formulation as described above. The present invention provides, for example, the following items: (Item 1) a) Approximately 20-90% by weight, or approximately 30-75% by weight, or approximately 40-70% by weight of microcrystalline cellulose, b) A biogum of at least one microbial origin in an amount of approximately 10 to approximately 80% by weight, or approximately 20 to approximately 75% by weight, or approximately 25 to 45% by weight, c) An emulsifier composition comprising 0 to about 20% by weight, or about 5 to about 15% by weight, or about 8 to 12% by weight, of at least one cellulose ether or its derivative, all of which are based on the weight of the total composition. (Item 2) The emulsifier composition described in item 1, wherein the weight ratio of (a):(b):(c) is approximately 2 to approximately 8(a), approximately 1 to approximately 20(b), and (c) is 1. (Item 3) The emulsifier composition according to item 1 or 2, wherein the at least one biogum of microbial origin is selected from xanthan gum, pullulan gum, sphinganexopolysaccharide, and mixtures thereof. (Item 4) The emulsifier composition according to any one of items 1 to 3, wherein the at least one cellulose ether or derivative thereof is selected from methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxyethylmethylcellulose, methylhydroxyethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, carboxymethylcellulose, sodium carboxymethylcellulose, and mixtures thereof. (Item 5) The emulsifier composition according to any one of items 1 to 4, wherein the at least one biogum of microbial origin comprises a biogum produced by aerobic microbial fermentation. (Item 6) The emulsifier composition according to any one of items 1 to 5, wherein the biogum of at least one microbial origin comprises a sphingan exopolysaccharide. (Item 7) The emulsifier composition according to any one of items 1 to 6, wherein the at least one biogum of microbial origin comprises dieutan gum. (Item 8) The emulsifier composition according to any one of items 1 to 7, wherein the at least one cellulose ether or derivative thereof comprises sodium carboxymethylcellulose. (Item 9) i) Aqueous phase and, ii) Oil phase and iii) A personal care formulation comprising an emulsifier composition described in any one of items 1 to 8. (Item 10) The personal care formulation according to item 9, wherein the formulation is an emulsion and the aqueous phase is a continuous phase. (Item 11) The personal care formulation according to item 9, wherein the formulation is an emulsion and the oil phase is a continuous phase. (Item 12) A personal care formulation according to any one of items 9 to 11, further comprising personal care active ingredients, pharmaceutical active ingredients, and mixtures thereof. (Item 13) A personal care formulation according to any one of items 9 to 12, further comprising fatty alcohols, glyceryl caprylate, polyglyceryl-3 laurate, glyceryl stearate, glyceryl citrate stearate, cetearyl olivate, sorbitan olivate, sodium stearate or potassium stearate, sucrose esters of fatty acids, lactate, and a coemulsifier selected from the group consisting of mixtures thereof. (Item 14) A personal care formulation as described in any one of items 9 to 13, further comprising a starch derivative. (Item 15) A personal care formulation according to any one of items 9 to 14, wherein the emulsifier composition is present in an amount of about 0.1 to about 5% by weight or about 0.2 to 1.5% by weight, based on the weight of the total composition. (Item 16) A personal care formulation according to any one of items 9 to 15, wherein the oil phase is present in an amount of about 5 to about 50% by weight based on the total weight of the composition. (Item 17) A method for preparing a personal care formulation as defined in any one of items 9 to 16, (i) Dispersing the emulsifier composition described in any one of items 1 to 8 in the aqueous phase, (ii) Stirring the oil phase in the aqueous phase to form an emulsion, and optionally, (iii) A method comprising adjusting the pH of the emulsion to less than 7. (Item 18) A method for stabilizing a composition comprising an oil phase and an aqueous phase, comprising the step of mixing an emulsifier composition according to any one of items 1 to 8 with the oil phase and the aqueous phase. (Item 19) Use of any one of the compositions described in item 1 to 8 for stabilizing an emulsion containing an oil phase and an aqueous phase. [Modes for carrying out the invention]

[0024] As used herein, the term “comprising” is intended to be comprehensive or unrestrictive and not exclude additional unlisted elements or method steps, and to encompass the phrases “consisting essentially of” and “consisting of” as alternative embodiments, where “consisting of” excludes any elements or steps not specified, and “consisting essentially of” allows for the inclusion of additional unlisted elements or steps that do not substantially affect the essential or basic and novel features of the composition or method under consideration.

[0025] When the concentrations of components in a composition are provided in the form of percentages, it should be understood that the sum of the concentrations in the composition does not exceed 100%.

[0026] Emulsifier composition As used herein, the terms “emulsifier composition” or “emulsifier system” refer to a mixture or combination of components that can stabilize or improve the stability of an emulsion. Emulsion stability can be defined as the ability of an emulsion to resist changes in its physicochemical properties over time. An emulsion is generally considered stable if it is resistant to physical changes over a practical length of time. The stability of an emulsion can be tested by several methods, including centrifugation, filtration, shaking or stirring, low-intensity ultrasonic vibration, heating, or simply by observing an emulsion that has been left standing for a period of time. Instability in an emulsion results in the suspension of dispersed phases to the surface of droplets, creaming precipitation, accretion between droplets, droplet fusion, and ultimately phase separation. To prevent droplet fusion and achieve reasonable droplet stability, it is necessary to form an energy barrier at the oil-water interface in the emulsion. Emulsifiers provide this energy barrier by forming a stabilizing layer, such as a polymer or solid particles, that adsorbs at the oil-water interface. The emulsifier reduces interfacial tension, preventing emulsion droplets from adhering to or from adhering to each other.

[0027] The emulsifier composition of the present invention, a) Microcrystalline cellulose and, b) A biogum of at least one microbial origin, and optionally, c) To provide an emulsifier composition comprising at least one cellulose ether or a derivative thereof.

[0028] Typically, microcrystalline cellulose is present in an amount of about 20 to about 90% by weight based on the total weight of the composition. Typically, at least one biogum of microbial origin is present in the composition in an amount of about 10 to about 80% by weight based on the total weight of the composition. "At least one" means "one or two or more." Therefore, the emulsifier composition contains one biogum of microbial origin or two or more biogums of microbial origin. Typically, at least one cellulose ether or its derivative is present, if present, in an amount of up to about 20% by weight based on the total weight of the composition. Therefore, the emulsifier composition may contain one or more cellulose ethers or their derivatives in up to about 20% by weight.

[0029] Since the emulsifier composition of the present invention is not surfactant, it does not tend to have adverse effects on the skin such as irritation. Therefore, emulsions produced using the emulsifier composition of the present invention are also unlikely to have adverse effects on the skin such as skin irritation. Furthermore, emulsions produced using the emulsifier composition of the present invention have excellent or improved sensory and rheological properties, possess a quick-break effect (i.e., can spread easily on the skin and leave no residue), and do not require the very small droplet size generally required to obtain a stable emulsion, thus eliminating the need for high-energy emulsification methods to produce the emulsion. This last advantage means that the method for producing emulsions using the emulsifier composition of the present invention is relatively technically simple, and therefore relatively inexpensive, and can be easily scaled up. It is also particularly noteworthy that the emulsifier composition of the present invention contains natural ingredients and is therefore environmentally friendly and more well-received by consumers.

[0030] The emulsifier composition of the present invention, a) Approximately 20 to 90% by weight of microcrystalline cellulose, b) May contain at least one biogum produced by microbial fermentation in an amount of approximately 10 to approximately 80% by weight, Weight percent refers to weight percent based on the total weight of the emulsifier composition.

[0031] Furthermore, the emulsifier composition of the present invention is a) Approximately 20 to 90% by weight of microcrystalline cellulose, b) At least one biogum produced by microbial fermentation, in an amount of approximately 10 to 80% by weight, c) may include at least one cellulose ether or derivative thereof, the at least one cellulose ether or derivative thereof present in an amount of up to about 20% by weight, Weight percent refers to weight percent based on the total weight of the emulsifier composition.

[0032] Component a) The emulsifier composition contains microcrystalline cellulose (MCC). MCC is purified and partially depolymerized cellulose. Naturally occurring cellulose contains both crystalline and amorphous regions. In contrast, MCC corresponds to the isolated crystalline portion of cellulose that lacks amorphous regions. The isolation of MCC from naturally occurring cellulose typically involves the removal of amorphous regions from the purified cellulose material by hydrolysis using a strong acid. Typically, MCC is in the form of particulate aggregates, sometimes called "crystallites," with an average particle size in the range of 1 to 400 microns, more commonly in the range of 10 to 250 microns. The MCC used in this invention may have an average particle size of 10 to 250 microns or 10 to 200 microns as measured by laser diffraction.

[0033] Advantageously, MCC is present in an amount of about 30 to about 75% by weight, or about 40 to about 70% by weight, based on the total amount of the composition.

[0034] component b) The emulsifier composition comprises at least one biogum of microbial origin. A biogum of microbial origin means a biogum produced or that can be produced by microbial fermentation. As used herein, a biogum of microbial origin is a polymer, such as a polysaccharide, obtained or that can be obtained by microbial fermentation. In this context, the term "polymer" is interchangeable with the term "biopolymer." In particular, a biogum of microbial origin is a polymer, such as a polysaccharide, obtained or that can be obtained by microbial fermentation of carbohydrates. The microorganism can be selected from bacteria or fungi. The fermentation may be aerobic fermentation.

[0035] At least one biogum of microbial origin can be selected from xanthan gum, pullulan gum, sphinganexopolysaccharide, and mixtures thereof. Therefore, at least one biogum of microbial origin may be a biogum selected from xanthan gum, pullulan gum, and sphinganexopolysaccharide, or a mixture of biogums selected from xanthan gum, pullulan gum, and sphinganexopolysaccharide.

[0036] Xanthan gum is a biogum that can be produced by fermentation by bacteria of the genus Xanthomonas, such as Xanthomonas campestris. More specifically, xanthan gum is a polysaccharide that can be produced, or obtained, by fermentation of carbohydrates by bacteria of the genus Xanthomonas, such as Xanthomonas campestris. In particular, xanthan gum is produced by fermentation of carbohydrates by bacteria of the species Xanthomonas campestris. Xanthan gum is a water-soluble polysaccharide with a high molecular weight (approximately 1000 kDa). Xanthan gum contains (or mainly consists of) hexose units of D-glucose, D-mannose, and D-glucuronic acid.

[0037] Pullulan gum is a biogum that can be produced by the fermentation of the fungus Aureobasidium pullulans. More specifically, pullulan is a polysaccharide that can be produced, or obtained, by the fermentation of carbohydrates, particularly starch, by the fungus Aureobasidium pullulans. Pullulan is a polysaccharide consisting of maltotriose units (three glucose units linked by α-1,4 glycosidic bonds) linked to each other by α-1,6 glycosidic bonds.

[0038] The terms "sphingan exopolysaccharide" and "sphingan" are used interchangeably herein. Sphingan is a biogum that can be produced by bacteria of the genus Sphingomonas. Sphingan is a structurally closely related bacterial exopolysaccharide produced by members of the genus Sphingomonas. Sphingan exopolysaccharide can be produced, i.e., obtained, by the fermentation of carbohydrates by bacteria of the genus Sphingomonas. The most commonly known sphingan includes jelan, welan, ramsan, and diyutan, which exhibit excellent rheological properties. Sphingan is structurally related by a main chain containing the sugars D-glucose, D-glucuronic acid, and L-rhamnose (or L-mannose), but differs in the properties and position of their side chains, as well as the presence or absence of acyl groups. Detailed structural information on sphingan can be found in the literature, for example, in the book *The Family Sphingomonadaceae* by Glaeser SP, Kampfer P. (2014), and in *The Prokaryotes* by Rosenberg E., DeLong EF, Lory S., Stackebrandt E., Thompson F. (eds), *The Prokaryotes*, Springer, Berlin, Heidelberg. At least one biogum of microbial origin can be selected from the group of sphingan exopolysaccharides consisting of gellan, wellan, dieutan gum, and mixtures thereof. Thus, at least one biogum of microbial origin may be a biogum selected from gellan, wellan, and dieutan gum, or a mixture of biogums selected from gellan, wellan, and dieutan gum.

[0039] Wellan gum is a biogum that can be produced by bacterial fermentation from the genera Alcaligenes or Sphingomonas. More specifically, wellan gum is an exopolysaccharide that can be produced, i.e., obtained, by the fermentation of carbohydrates by bacteria from the genera Alcaligenes or Sphingomonas. Wellan gum is a polymer having a repeating tetrasaccharide backbone containing L-mannose, L-rhamnose, D-glucose, and D-glucuronic acid. In a particular embodiment, wellan gum is obtained by bacterial fermentation of carbohydrates from the genera Sphingomonas.

[0040] Gellan gum is a biogum that can be produced by the fermentation of bacteria of the species Sphingomonas elodea. Gellan gum is a water-soluble anionic polysaccharide produced by Sphingomonas elodea bacteria. More specifically, gellan gum is an exopolysaccharide that can be produced, i.e., obtained, by the fermentation of carbohydrates by bacteria of the species Sphingomonas elodea. It is a polymer having a tetrasaccharide as a repeating unit, consisting of two residues of D-glucose, and one residue each of L-rhamnose and D-glucuronic acid.

[0041] Dieutan gum, also known as the heteropolysaccharide S-657, is a biogum produced by the fermentation of bacterial strains of the genus Shingomonas, such as the Shingomonas strain deposited in the American Type Culture Collection (ATCC) with deposit number ATCC53159. More specifically, dieutan gum is an exopolysaccharide that can be produced, or obtained, by the fermentation of carbohydrates by bacteria of the genus Shingomonas, particularly the Shingomonas strain with deposit number ATCC53159. Dieutan generally exhibits a hexamer repeat unit consisting of four sugars in the main chain (glucose-glucuronic acid-glucose-rhamnose) and side chains of two rhamnose residues bonded to one of the glucose residues. One non-exclusive example of commercially available dieutan gum is Kelcocare® dieutan gum from CP Kelco. Dieutan gum is also commonly referred to as the S-657 polysaccharide.

[0042] Advantageously, at least one biogum of microbial origin may be present in an amount of about 20 to about 75% by weight, or about 25 to about 45% by weight, or about 25 to about 35% by weight, based on the total weight of the composition.

[0043] Surprisingly, dieutan gum was found to provide a synergistic emulsifying effect when combined with MCC, particularly when combined with MCC and at least one cellulose ether. Therefore, in one embodiment, the biogum of at least one microbial origin is or comprises dieutan gum.

[0044] Ingredient c) The emulsifier composition may optionally contain at least one cellulose ether or a derivative thereof.

[0045] Cellulose ethers are cellulose derivatives in which the hydrogen atoms of the hydroxyl groups of the glucopyranose monomer constituting the cellulose main chain are substituted with, for example, alkyl groups, hydroxyalkyl groups, or carboxyalkyl groups. The degree of hydrogen atom substitution varies. The cellulose ethers and their derivatives used in the present invention are water-dispersible. Examples of cellulose ethers include alkylcellulose, hydroxyalkylcellulose, and carboxyalkylcellulose. Typically, each alkyl group is independently C1-C4, C1-C3, C1-C2, or C1 alkyl group. Examples of derivatives of cellulose ethers include salts of carboxyalkylcellulose, such as sodium salts. Therefore, at least one cellulose ether or derivative thereof may be a cellulose ether or derivative thereof selected from alkylcellulose, hydroxyalkylcellulose, carboxyalkylcellulose, and sodium salts of carboxyalkylcellulose, and at least one cellulose ether or derivative thereof may be a mixture of cellulose ethers or derivatives thereof selected from alkylcellulose, hydroxyalkylcellulose, carboxyalkylcellulose, and sodium salts of carboxyalkylcellulose. Preferably, each alkyl group is independently C1-C3, C1-C2, or C1 alkyl group. Non-limiting examples of suitable cellulose ethers and their derivatives include methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxyethylmethylcellulose, methylhydroxyethylcellulose, hydroxypropylcellulose (HPC), hydroxypropylmethylcellulose (HPMC), carboxymethylcellulose (CMC), sodium carboxymethylcellulose (NaCMC), and mixtures thereof. NaCMC is also commonly known as cellulose gum.NaCMC is a cellulose derivative having carboxymethyl groups attached to some of the hydroxyl groups of the glucopyranose monomer that constitutes the cellulose main chain.

[0046] Advantageously, if present, at least one cellulose ether or its derivative may be present in an amount of about 5 to about 20% by weight, about 5 to about 15% by weight, or about 8 to about 12% by weight, based on the total weight of the composition.

[0047] The presence of sodium carboxymethylcellulose (NaCMC) in the emulsifier composition of the present invention has been found to significantly improve the stability of the emulsion and the sensory properties of the personal care formulation (such as improved spreadability, reduced stickiness, no residue left on the skin, and no alteration of oil properties).

[0048] The emulsifier composition of the present invention, a) Approximately 30-75% by weight or approximately 40-70% by weight of microcrystalline cellulose, b) At least one biogum produced by microbial fermentation, in an amount of approximately 20-75% by weight, and optionally, c) May contain at least one cellulose ether or derivative thereof in an amount of approximately 5 to approximately 15% by weight, Weight percent refers to weight percent based on the total weight of the emulsifier composition.

[0049] The emulsifier composition of the present invention, a) Approximately 30-75% by weight or approximately 40-70% by weight of microcrystalline cellulose, b) At least one biogum produced by microbial fermentation, in an amount of approximately 20-75% by weight, and optionally, c) May contain at least one cellulose ether or derivative thereof in an amount of approximately 8 to approximately 12% by weight. Weight percent refers to weight percent based on the total weight of the emulsifier composition.

[0050] The emulsifier composition of the present invention, a) Approximately 30-75% by weight or approximately 40-70% by weight of microcrystalline cellulose, b) At least one biogum produced by microbial fermentation, in an amount of approximately 25-45% by weight, and optionally, c) May contain at least one cellulose ether or derivative thereof in an amount of approximately 5 to approximately 15% by weight, Weight percent refers to weight percent based on the total weight of the emulsifier composition.

[0051] The emulsifier composition of the present invention, a) Approximately 30-75% by weight or approximately 40-70% by weight of microcrystalline cellulose, b) At least one biogum produced by microbial fermentation, in an amount of approximately 25-45% by weight, and optionally, c) May contain at least one cellulose ether or derivative thereof in an amount of approximately 8 to approximately 12% by weight. Weight percent refers to weight percent based on the total weight of the emulsifier composition.

[0052] The emulsifier composition of the present invention, a) Approximately 30-75% by weight or approximately 40-70% by weight of microcrystalline cellulose, b) At least one biogum produced by microbial fermentation, in an amount of approximately 25-35% by weight, and optionally, c) May contain at least one cellulose ether or derivative thereof in an amount of approximately 5 to approximately 15% by weight, Weight percent refers to weight percent based on the total weight of the emulsifier composition.

[0053] The emulsifier composition of the present invention, a) Approximately 30-75% by weight or approximately 40-70% by weight of microcrystalline cellulose, b) At least one biogum produced by microbial fermentation, in an amount of approximately 25-35% by weight, and optionally, c) May contain at least one cellulose ether or derivative thereof in an amount of approximately 8 to approximately 12% by weight. Weight percent refers to weight percent based on the total weight of the emulsifier composition.

[0054] The ratio of components a), b), and c)(c)(if present) may favorably affect the properties of the composition.

[0055] The weight ratio of MCC to microbial biogum can be 1:2 to 4:1. In particular, the concentration of MCC may be higher than that of microbial biogum, and the concentration is expressed as a weight % based on the total weight of the emulsifier composition. For example, the weight ratio of a) to b) can be 2:1 to 4:1.

[0056] The weight ratio of MCC:cellulose ether or its derivatives may be 10 to 2:1, more specifically 9 to 3:1, and more specifically 5 to 3:1.

[0057] The weight ratio of MCC (microorganism-derived biogum) to cellulose ether or its derivative is 2-8 parts MCC, 1-20 parts biogum, and 1 part cellulose ether, i.e., 2-8:1-20:1. Advantageously, the ratio is 3-6 parts MCC, 1-10 parts biogum, and 1 part cellulose ether (3-6:1-10:1), or 4-5.5 parts MCC, 1-3.5 parts biogum, and 1 part cellulose ether (4-5.5:1-3:1), or 4.5-5.5 parts MCC, 1.5-3 parts biogum, and 1 part cellulose ether (4-5.5:1.5-3:1).

[0058] Exemplary embodiments of the emulsifier composition of the present invention include the following: I a) Approximately 40-70% by weight of microcrystalline cellulose, b) At least one biogum produced by microbial fermentation in an amount of approximately 25 to approximately 35% by weight, wherein the at least one biogum is diyutan or contains diyutan, c) An emulsifier composition comprising about 8 to about 12% by weight of at least one cellulose ether or a derivative thereof, An emulsifier composition in which weight % refers to weight % based on the total weight of the emulsifier composition, and the weight ratio of a):b):c) is 2-8:1-20:1 or 3-6:1-10:1. II a) Approximately 40-70% by weight of microcrystalline cellulose, b) A biogum comprising approximately 25 to approximately 35% by weight of at least one biogum produced by microbial fermentation, wherein the at least one biogum is diyutan or contains diyutan, c) An emulsifier composition comprising at least one cellulose ether or derivative thereof in an amount of about 8 to about 12% by weight, wherein the at least one cellulose ether or derivative thereof is or contains carboxymethylcellulose sodium, An emulsifier composition in which weight % refers to weight % based on the total weight of the emulsifier composition, and the weight ratio of a):b):c) is 2-8:1-20:1 or 3-6:1-10:1.

[0059] Other components may be present in the emulsifier composition, including co-emulsifiers, thickeners, dispersants, fragrances or other additives having a fragrance function, pigments, preservatives, and combinations thereof. These may be present in amounts up to 20 or 10% by weight of the emulsifier composition, i.e., if c) is not present, the emulsifier composition contains at least 80 or 90% by weight of components a) and b), and if c) is present, the emulsifier composition contains at least 80 or 90% by weight of components a), b), and c).

[0060] Preferably, the emulsifier composition of the present invention is anhydrous. As used herein, the term “anhydrous” means that the emulsifier composition contains up to 10% by weight of water. In particular, the emulsifier composition contains up to 7% by weight of water based on the total weight of the composition, more specifically, up to 5% by weight or up to 2% by weight of water. The emulsifier composition may contain only residual amounts of water from the raw materials used. The emulsifier composition may essentially consist of components a), b), and c), and any impurities present, for example, are attributable to the raw materials used.

[0061] The emulsifier composition of the present invention is not surfactant; its surfactant nature is defined in Example 3.

[0062] Personal care formulations The emulsifier composition of the present invention is suitable for use in forming and stabilizing emulsions that can be used in personal care formulations. The present invention extends to emulsions comprising the emulsifier composition described herein. The emulsion may include i) an aqueous phase, ii) an oil phase, and iii) the emulsifier composition described herein. The present invention extends to personal care formulations comprising the emulsifier composition described herein. The personal care formulation may include i) an aqueous phase, ii) an oil phase, and iii) the emulsifier composition described herein.

[0063] As used herein, the term “personal care” includes, but is not limited to, cosmetics, toiletries, medicinal cosmetics, beauty aids, insect repellents, personal hygiene and cleansing products applied to the body, including the skin, hair, scalp, and nails of humans and animals.

[0064] The emulsion or personal care formulation of the present invention comprises an oil phase. As used herein, the term "oil" means a compound or mixture of compounds that is insoluble in water and has the appearance of a liquid at a temperature of 25°C. The oil phase is not limited to a specific oil. Any oil suitable for cosmetic or personal care formulations can be used, including but not limited to vegetable oils, petroleum-derived oils (e.g., mineral oil, liquid paraffin), fatty acid esters, etc.

[0065] The oil phase may contain at least one of ester oils, vegetable oils, alcohols, paraffin oils, or silicones. The oil phase may include mineral oils, e.g., paraffin oil, petrolatum, isoparaffin, or white mineral oil; oils of animal origin, e.g., squalene or squalane; vegetable oils, e.g., vegetable squalane, sweet peach oil, coconut oil, castor oil, jojoba oil, olive oil, rapeseed oil, peanut oil, sunflower oil, wheat germ oil, corn germ oil, soybean oil, cottonseed oil, alfalfa oil, poppy oil, pumpkin oil, evening primrose oil, millet oil, barley oil, rye oil, safflower oil, kukui oil, passionflower oil, hazelnut oil, Coconut oil, shea butter, apricot kernel oil, coriander seed oil, beech oil, calophyllum oil, sisinbrium oil, avocado oil, calendula oil, oils derived from flowers or vegetables, ethoxylated vegetable oils; synthetic oils, such as fatty acid esters, such as butyl myristate, propyl myristate, isopropyl myristate, cetyl myristate, isopropyl palmitate, octyl palmitate, butyl stearate, hexadecyl stearate, isopropyl stearate, octyl stearate, The material may contain one or more oils selected from isocetyl stearate, dodecyl oleate, hexyl laurate, propylene glycol dicaprylate, esters derived from lanolin fatty acids, such as isopropyl lanolinate, isocetyl lanolinate, monoglycerides, diglycerides, and triglycerides of fatty acids, such as glycerol triheptanoate, alkyl benzoates, hydrogenated oils, poly(alpha-olefins), polyolefins, such as poly(isobutane), synthetic isoalkanes, such as isohexadecane, isododecane, perfluorinated oils; silicone oils, such as dimethylpolysiloxane, methylphenylpolysiloxane, amine-modified silicones, fatty acid-modified silicones, alcohol-modified silicones, alcohol-modified silicones and fatty acids, silicone-modified silicone polyether groups, modified epoxy silicones, fluoride-modified silicones, cyclic silicones, and alkyl-modified silicones.

[0066] The oil phase may contain, for example, other oil-soluble components. The oil phase may contain one or more oils in an amount of at least 90% by weight, at least 95% by weight, or at least 98% by weight, based on the total weight of the oil phase.

[0067] The emulsion or personal care formulation of the present invention comprises an aqueous phase. The aqueous phase comprises water and may contain, for example, other water-soluble components. The aqueous phase may contain at least 90% by weight, at least 95% by weight, or at least 98% by weight of water, based on the total weight of the aqueous phase.

[0068] Emulsions or personal care formulations may be oil-in-water (O / W) emulsions, water-in-oil (W / O) emulsions, or oil-in-polyol (e.g., glycerol) emulsions. Emulsions or personal care formulations may be multiple emulsions in which O / W and W / O emulsions exist in a single system. In multiple emulsions, the dispersed phase is itself an emulsion containing droplets of another phase. The dispersed phase may be a multiple emulsion such as a water-in-oil-in-water (W / O / W) or an oil-in-water-in-oil (O / W / O) emulsion.

[0069] The emulsion or personal care formulation may be a W / O emulsion, i.e., an emulsion in which the oil phase is a continuous phase and the aqueous phase is a dispersed phase. Typically, in this embodiment, the oil phase has a larger volume than the aqueous phase.

[0070] In particular, emulsions or personal care formulations can be O / W emulsions in which the aqueous phase forms a continuous phase and the oil phase forms a dispersed phase. The emulsifier compositions of the present invention exhibit remarkably improved performance in O / W emulsions compared to other emulsifier compositions or systems. For example, the emulsifier compositions of the present invention can be used to enable the presence of higher concentrations of oil in O / W emulsions and to produce more stable emulsions compared to those obtained using other emulsifier systems, and are effective when present at relatively low concentrations.

[0071] If the emulsion or personal care formulation is an O / W emulsion, the oil phase may be present in an amount of 1 to 50% by weight based on the total weight of the emulsion or personal care formulation. As described above, one of the advantages of the emulsifier composition of the present invention is that it can facilitate the provision of emulsions having a high oil content. Therefore, the oil phase may be present in an amount of 5% or more by weight, particularly 20%, 30%, or 40% or more by weight, based on the total weight of the emulsion or personal care formulation. The oil phase may be present in an amount of 5 to 40% by weight, specifically 10 to 30% by weight, more specifically 20 to 30% by weight, based on the total weight of the emulsion or personal care formulation.

[0072] Preferably, the emulsion or personal care formulation of the present invention contains at least 0.1% by weight of the emulsifier composition of the present invention, based on the total weight of the emulsion or personal care formulation. The emulsifier composition may be present in the emulsion or personal care formulation in an amount of 0.1 to 5% by weight, specifically 0.2 to 1.5% by weight, and more specifically 0.5 to 1% by weight, based on the total weight of the emulsion or personal care formulation. The amount of emulsifier composition present in the emulsion or personal care formulation may be 0.6, 0.7, 0.8, and 0.9% by weight, based on the total weight of the emulsion or personal care formulation. In one embodiment, the emulsifier composition is present in the emulsion or personal care formulation in an amount of 0.7% by weight, based on the total weight of the emulsion or personal care formulation.

[0073] Therefore, the present invention is i) Aqueous phase and, ii) Oil phase and iii) To provide an emulsion or personal care formulation comprising at least 0.1% by weight of the emulsifier composition of the present invention, Weight percentages are based on the total weight of the emulsion or personal care formulation.

[0074] The amount of MCC present in the emulsion or personal care formulation may range from 0.05 to 5.0% by weight based on the total weight of the emulsion or personal care formulation. Advantageously, the MCC may be present at 0.1 to 2.5% by weight, specifically 0.1 to 1.0% by weight, specifically 0.1 to 0.49% by weight, and more specifically 0.35 to 0.45% by weight, based on the total weight of the emulsion or personal care formulation. The MCC concentration may be 0.45, 0.42, 0.40, 0.38, or 0.35% by weight, based on the total weight of the emulsion or personal care formulation.

[0075] The amount of microbial biogum present in the emulsion or personal care formulation may range from 0.02 to 2.5% by weight based on the weight of the emulsion or formulation. Advantageously, the microbial biogum may be present in an amount of 0.05 to 1.5% by weight, specifically 0.05 to 0.5% by weight, and more specifically 0.1 to 0.3% by weight based on the total weight of the emulsion or formulation. Microbial biogum may be present in the personal care formulation in amounts of 0.25, 0.2, or 0.15% by weight based on the total weight of the emulsion or personal care formulation.

[0076] The amount of cellulose ether or its derivative present in the emulsion or personal care formulation may range from 0 to 1% by weight based on the total weight of the emulsion or formulation. Advantageously, the amount of cellulose ether may be 0.01 to 0.5% by weight, particularly 0.05 to 0.2% by weight, or 0.06 to 0.1% by weight based on the total weight of the emulsion or formulation. Cellulose ether or its derivative may be present in the emulsion or personal care formulation in amounts of 0.02, 0.04, 0.05, 0.06, 0.08, 0.12, or 0.14% by weight based on the total weight of the emulsion or formulation.

[0077] Therefore, the present invention is i) Aqueous phase and, ii) Oil phase and iii) 0.05~5.0% by weight of MCC, iv) 0.02-2.5% by weight of biogum of at least one microbial origin, v) Provides an emulsion or personal care formulation comprising 0 to 1% by weight of at least one cellulose ether or a derivative thereof, Weight percentages are based on the total weight of the emulsion or personal care formulation.

[0078] The emulsions and personal care formulations of the present invention can be prepared by common conventional emulsification and mixing methods known to those skilled in the art. One of the advantages of the emulsifier compositions according to the present invention is that, when used to form emulsions, they do not require very small droplet sizes in the dispersed phase, and therefore do not require high-energy emulsification methods in the preparation of emulsions. This results in a formulation process that is technically simpler, less expensive, and easier to scale up.

[0079] The present invention provides a method for preparing an emulsion or personal care formulation comprising an oil phase and an aqueous phase, the method comprising the step of mixing the emulsifier composition of the present invention with the oil phase and the aqueous phase. Preferably, the emulsifier composition is first mixed with the aqueous phase, and then the oil phase is mixed with the mixture of the aqueous phase and the emulsifier composition. The emulsion or personal care formulation may be as described herein.

[0080] A method for preparing an emulsion or personal care formulation is: i) A step of dispersing the emulsifier composition of the present invention in an aqueous phase, ii) A step of stirring the oil phase into the aqueous phase to form an emulsion, iii) The process may include a step of adjusting the pH of the emulsion to less than 7.

[0081] The stirring conditions in step ii) are preferably slow stirring conditions, and may include stirring at a stirring speed of 5,000 to 20,000 rpm, particularly 8,000 to 12,000 rpm. In one embodiment, the stirring speed is less than 12,000 rpm. The emulsion or personal care formulation may be as described herein.

[0082] In step iii), the pH is adjusted, preferably by using an acid, preferably a weak acid such as citric acid. In step iii), the pH can be adjusted to 5.5.

[0083] The present invention provides a method for stabilizing an emulsion comprising an oil phase and an aqueous phase, comprising the step of mixing the emulsifier composition of the present invention with the oil phase and the aqueous phase. Preferably, the emulsifier composition is first mixed with the aqueous phase, and then the oil phase is mixed with the mixture of the aqueous phase and the emulsifier composition. The emulsion may be as described herein or a personal care formulation as described herein.

[0084] The present invention provides the use of the emulsifier composition of the present invention for stabilizing emulsions comprising an oil phase and an aqueous phase. The emulsion may be an emulsion described herein or a personal care formulation described herein.

[0085] The personal care formulation may be in the form of a lotion, cream, or gel cream, or any form of emulsion known in the art.

[0086] The personal care formulations are preferably skincare products, such as sunscreens, cosmetics, antiperspirants, hair removal or dermatological products, or haircare products, such as shampoos, conditioners, hair dyes, or hair relaxer products.

[0087] Personal care formulations may also include fabrics, nonwovens, clothing, medical devices, and means for immobilizing compounds thereon. Preferred fabrics, nonwovens, clothing, and medical devices include belts, gauze, T-shirts, socks, tights, underwear, girdles, gloves, diapers, sanitary napkins, bandages, bed covers, wipes, adhesive patches, non-adhesive patches, occlusive patches, microelectropatch, and / or face masks.

[0088] The personal care formulation of the present invention may contain other components such as co-emulsifiers and rheological modifiers. Preferably, the other components are present in an amount of less than 10% by weight of the personal care formulation, specifically less than 5% by weight, and more specifically less than 1% by weight. In addition, or alternatively, a combination of the aqueous phase, oil phase, and emulsifier composition is present in an amount of more than 90% by weight of the personal care formulation, specifically more than 95% by weight, and more specifically more than 99% by weight.

[0089] Co-emulsifier The addition of further co-emulsifiers to personal care formulations may be advantageous. The term "co-emulsifier" is well known in the art. It generally refers to a compound that is combined with an emulsifier to improve the viscosity and stability of the resulting emulsion.

[0090] The concentration of the coemulsifier may range from 0.1 to 2% by weight, more specifically 0.2 to 1% by weight, and more specifically 0.4 to 0.6% by weight, based on the final weight of the formulation. One of the advantages of the emulsifier composition of the present invention is that, when used to form an emulsion, the concentration of the coemulsifier can be lower than the concentration required for other emulsion systems. This avoids the problem of skin irritation or loss of sensory parameters and consumer acceptability that can occur when surfactants are used as coemulsifiers. Therefore, preferably, the concentration of the coemulsifier is less than 0.6% by weight based on the total weight of the formulation.

[0091] Naturally derived co-emulsifiers are particularly advantageous in the context of the present invention. Examples of natural co-emulsifiers include, but are not limited to, fatty alcohols, glyceryl caprylate, polyglyceryl-3 laurate, glyceryl stearate, glyceryl citrate stearate, cetearyl olivate, sorbitan olivate, potassium cetyl phosphate, sodium or potassium stearate, sucrose, sucrose esters of fatty acids, lactates, and mixtures thereof.

[0092] As used herein, the term “fatty alcohol” refers to long-chain primary alcohols preferably having a chain length of 16 to 26 carbon atoms, and may be derived from natural sources such as fats and oils. Examples of fatty alcohols suitable for the present invention include, but are not limited to, a group selected from the group including cetyl alcohol, cetostearyl alcohol, palmitrail alcohol, stearyl alcohol, isostearyl alcohol, oleyl alcohol, arachidyl alcohol, behenyl alcohol, isobehenyl alcohol, erucyl alcohol, lignceryl alcohol, and serotinyl alcohol. In particular, the fatty alcohol used in the present invention is selected from cetyl alcohol, cetostearyl alcohol (or cetearyl alcohol), stearyl alcohol, isostearyl alcohol, arachidyl alcohol, behenyl alcohol, isobehenyl alcohol, lignceryl alcohol, and serotinyl alcohol. More specifically, the fatty alcohol is cetostearyl alcohol.

[0093] Personal care formulations may also contain alkoxylated fatty alcohols as coemulsifiers. Alkoxylated fatty alcohols are known in the art. As such, their production will be well known to those skilled in the art.

[0094] In particular, glyceryl caprylate and polyglyceryl-3 laurate significantly improve the stability of the emulsion when combined with the emulsifier composition of the present invention. Therefore, in one embodiment, the co-emulsifier is selected from the group consisting of glyceryl caprylate, polyglyceryl-3 laurate, and mixtures thereof. More specifically, the co-emulsifier is polyglyceryl-3 laurate.

[0095] Rheological modifier Personal care formulations may further contain rheological modifiers, such as thickeners and / or gelling agents, to improve the rheology of the formulation depending on the specifications of the product.

[0096] Non-limiting examples include linear, branched, or crosslinked polymer electrolytes, such as partially or completely chlorinated acrylic acid homopolymers, partially or completely chlorinated methacrylic acid homopolymers, partially or completely chlorinated racide-2-methyl-[(1-oxo-2-propenyl)amino]-1-propanesulfonic acid (AMPS) homopolymers, acrylic acid and AMPS copolymers, acrylamide and AMPS copolymers, vinylpyrrolidone and AMPS copolymers, AMPS and 2-hydroxyethyl acrylic acid copolymers, AMPS and 2-hydroxyethyl methacrylic acid copolymers, AMPS and hydroxyethyl acrylamide copolymers, AMPS and N,N-dimethylacrylamide copolymers, and AMPS and tris(hydroxymethyl)acrylamide copolymers. Examples include copolymers of donkey)(THAM), copolymers of acrylic acid or methacrylic acid and (2-hydroxyethyl acrylate), copolymers of acrylic acid or methacrylic acid and (2-hydroxyethyl methacrylate), copolymers of acrylic acid or methacrylic acid and hydroxyethyl acrylamide, copolymers of acrylic acid or methacrylic acid and THAM, copolymers of acrylic acid or methacrylic acid and N,N-dimethylacrylamide, terpolymers of acrylic acid or methacrylic acid, AMPS and (2-hydroxyethyl acrylate), terpolymers of acrylic acid or methacrylic acid, AMPS and (2-hydroxyethyl methacrylate), terpolymers of acrylic acid or methacrylic acid, AMPS and THAM, terpolymers of acrylic acid or methacrylic acid, AMPS and N,N-dimethylacrylamide, terpolymers of acrylic acid or methacrylic acid, AMPS and acrylamide, and copolymers of acrylic acid or methacrylic acid and alkyl acrylate.

[0097] In one embodiment, the thickening agent and / or gelling agent of the present invention is of natural origin. Natural gums are of particular interest. Natural gums are non-cellulose polysaccharides derived from plant sources, seaweed, or produced through bacterial fermentation. Non-exclusive examples of natural plant gums include albidia gum, aloe mucus, beta-glucan, cassia gum, chicle gum, dammar gum, fenugreek gum, glucomannan, guar gum, gum arabic (also called acacia gum), copal gum, gatti gum, tragacanth gum, akega gum, hibiscus gum, American honey locust gum, hupu gum, karaya gum, kaya gum, pepper gum, carob gum, mastic gum, mimosa cabrera gum, mimosa gum, okra gum, plantain seed husk (also called ispacula husk), spruce gum, stercuria foetida gum, tamarind gum, tara gum, and any derivatives of any of the above. Examples of natural gums derived from seaweed include, but are not limited to, alginates or alginic acid, fucoidan, laminarin derived from brown algae, and agar and carrageenan derived from red algae. In a particular embodiment, the natural gum is selected from the group of tara gum or cassi gum.

[0098] The inventors have found that the addition of starch derivatives can be particularly useful in increasing the viscosity of the emulsion system to obtain a gel cream emulsion that may be of interest in certain cosmetic applications. Fluid emulsion lotions can also be obtained without the addition of starch derivatives. Non-limiting examples of starch derivatives include oxidized starch, dialdehyde starch, dextrin, British gum, acetyl starch, phosphate starch, carboxymethyl starch, hydroxyethyl starch, and hydroxypropyl starch. Compared to other emulsifier compositions, starch derivatives exhibit synergistic effects when combined with the MCC, at least one microbial biogum, and at least cellulose ether or its derivatives in the emulsifying composition of the present invention.

[0099] Starch derivatives may be present in personal care formulations in amounts of 0.1–2% by weight, particularly 0.2–1% by weight, based on the total weight of the formulation. More specifically, derivative starch derivatives may be present in personal care formulations in amounts of 0.3, 0.4, 0.5, 0.6, or 0.7% by weight, based on the total weight of the formulation.

[0100] The personal care formulation of the present invention may have a viscosity of 1,000 to 4,000 mPa·s, specifically 2,000 to 3,000 mPa·s, and more specifically 2,500 to 2,000 mPa·s, when the viscosity is determined in mPa·s at 25°C using a Brookfield LVT viscometer with an appropriate spindle depending on the viscosity of the emulsion, and tested at 20 rpm, 24 hours after the emulsion is prepared.

[0101] The personal care formulation of the present invention may contain at least one coemulsifier and at least one starch derivative.

[0102] Other optional components Personal care formulations may contain many different components that may be oil-soluble, water-soluble, or insoluble. Non-limiting examples of such components include preservatives, fragrances, humectants or solvents, e.g., alcohols, polyols, e.g., glycerol and polyethylene glycol, sunscreen or sunscreen components, alpha hydroxy acids, antimicrobial agents, vitamins and their precursors (e.g., vitamins A, B, C, D, F and their precursors), skincare active ingredients or agents, plant extracts, insecticides, essential oils, pigments (e.g., iron oxides and silicates, iron oxides, especially coated iron oxides, and / or titanium dioxide, and ceramic materials, e.g., boron nitride), deodorants or antiperspirants, depilators, hair care products (e.g., conditioners, hair dyes, hair relaxers, etc.), and combinations thereof.

[0103] Personal care formulations may contain preservatives common in personal care, such as, but not limited to, phenoxyethanol, formaldehyde solution, pentanediol, or sorbic acid.

[0104] Personal care compositions can be combined with antioxidants. Non-limiting examples include EDTA and its salts, citric acid, tartaric acid, oxalic acid, BHA (butylated hydroxyanisole), BHT (butylated hydroxytoluene), tocopherol derivatives such as tocopherol acetate, and mixtures thereof.

[0105] The personal care composition may further contain personal care active ingredients or pharmaceutically active agents. In the context of the present invention, as used herein, “personal care active ingredients” refers to ingredients that improve or enhance physical appearance. These are also commonly known as “cosmetic active ingredients.”

[0106] The cosmetically or pharmaceutically acceptable ingredients contained in the personal care formulations described in the present invention include ingredients commonly used in cosmetic or pharmaceutical compositions, for example, but not limited to, (i) anti-wrinkle agents, Botox-like agents, and / or anti-aging agents; (ii) firming agents, skin elasticity agents, and / or reconstructing agents; (iii) moisturizers; (iv) photoaging inhibitors, and / or blue light protectants, DNA protectants, DNA repair agents, and / or stem cell protectants; (v) free radical scavengers, and / or anti-glycation agents, detoxification agents, antioxidants, and / or anti-pollution agents; (v) agents that increase the transdermal absorption of any active compounds present; (vi) antiperspirants; (vii) melanin synthesis stimulants or inhibitors, whitening agents or depigmentants, prepigmentation agents, self-tanning agents; (viii) lipolytic agents or agents that stimulate lipolysis, lipogenic agents, etc.

[0107] In one embodiment, the personal care formulation is a cosmetic or pharmaceutical composition comprising a pharmaceutical or cosmetically effective amount of an adjuvant selected from the group consisting of (i) anti-wrinkle agents, Botox-like agents, and / or anti-aging agents, (ii) firming agents, skin elasticity agents, and / or reconstructing agents, (iii) moisturizers, (iv) photoaging inhibitors, and / or blue light protectants, (v) DNA protectants, DNA repair agents, and / or stem cell protectants, (vi) free radical scavengers, and / or anti-glycation agents, detoxifiers, antioxidants, and / or anti-pollution agents, and / or combinations thereof.

[0108] Anti-wrinkle agents, Botox-like agents, and / or anti-aging agents are marketed by Sederma / Croda and include Matrixyl® [INCI: Palmitoyl Pentapeptide-4], Matrixyl® 3000® [INCI: Palmitoyl Tetrapeptide-7, Palmitoyl Oligopeptide], Matrixyl® Synthe'6 [INCI: Glycerin, Water, Hydroxypropyl Cyclodextrin, Palmitoyl Tripeptide-38], and Matrixyl® Morphomics (trademark) [INCI: Pentylene glycol, Caprylyl glycol], Essenskin (trademark) [INCI: Hydroxymethionine calcium], Renovage [INCI: Teprenone], Dermaxyl (registered trademark) [INCI: Palmitoyl oligopeptide], Calmosensine [INCI: Butylene glycol, Acetyl dipeptide-1 cetyl ester], Volulip [INCI: Cetearyl ethylhexanoate, Sorbitan isostearate, Portulaca] Pilosa extract, coconut fatty acid sucrose, palmitoyl tripeptide-38, Subliskin [INCI: Sinorhizobium meliloti ferment, cetyl hydroxyethylcellulose, lecithin], Biopeptide CL [INCI: palmitoyl oligopeptide], Biopeptide EL [INCI: palmitoyl oligopeptide], Rigin [INCI: palmitoyl tetrapeptide-3], Biobustyl [INCI: polyglyceryl methacrylate, Rahnella / soy protein ferment, palmitoyl oligopeptide], Dynalift [INCI: sodium polystyrene sulfonate, Sorghum bicolor stem juice, glycerin], Idealift [INCI: acetyl dipeptide-1 cetyl ester], Siegesbeckia [INCI: SiegesbeckiaOrientales extract], Ovaliss [INCI: Coco-glucoside, caprylyl glycol, alcohol, glaucine], Juvinity (trademark) [INCI: Geranylgeraniisopropanol], Prolevis [INCI: Hydrolyzed vegetable protein], Idealift (trademark) [INCI: Hydroxyethylcellulose, acetyl dipeptide-1 cetyl ester], Beautifeye (trademark) [INCI: Albizia Julibrissin peel extract, daltoside], Chromocare (trademark) [INCI: Sigesbeckia Orientalis extract, Rabdosia Rubescens extract], or Resistem [Proposed INCI: Globularia Cordifolia ferment]. Vialox® [INCI: Pentapeptide-3], Syn®-Ake® [INCI: Dipeptide Diaminobutyroyl Benzylamide Diacetate], Syn®-Coll [INCI: Palmitoyl Tripeptide-5], Phytaluronate [INCI: Ceratonia Siliqua (Carob) Gum], and Preregen® [INCI: Glycine] are commercially available from Pentapharm / DSM. Soybean protein, oxidoreductase, Pepha-Nutrix [INCI: natural nutritional factors], Pepha-Tight [INCI: algae extract, pullulan], Pentacare-NA [INCI: hydrolyzed wheat gluten, carob mug], Syn(registered trademark)-Tacks [INCI: glycerin, palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine, palmitoyl dipeptide-6 diaminohydroxybutyrate], BeauActiveMTP [INCI: Hydrolyzed Milk Protein], Syn(registered trademark)-TC [INCI: Tetradecylaminobutyroylvalylaminobutyric acid urea trifluoroacetate, palmitoyl tripeptide-5, palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine], Syn(registered trademark)-Hycan [INCI: Tetradecylaminobutyroylvalylaminobutyric acid urea trifluoroacetate], Syn(registered trademark)-Glycan [INCI: Tetradecylaminobutyroylvalylaminobutyric acid urea trifluoroacetate], Regu-Age [INCI: Hydrolyzed Rice Bran Protein, Oxidoreductase, Glycine Soja Protein], Pepha-Timp [INCI: Human Oligopeptide-20], Pepha-Age [INCI: Dunaliella Salina Extract], Colhibin [INCI: Hydrolyzed Rice Protein], Elhibin [INCI: Glycine Soja protein, disodium cocoamphodiacetate, or All-Q(trademark) Plus [INCI: ubiquinone, tocopherol acetate]; Myoxinol(trademark) [INCI: hydrolyzed Hibiscus esculentus extract], Myoxinol(trademark) LS 9736 [INCI: hydrolyzed Hibiscus esculentus extract, dextrin], Syniorage(trademark) [INCI: acetyl tetrapeptide-11], Dermican(trademark) [INCI: acetyl tetrapeptide-9], DN-AGE(registered trademark) LS [INCI: Cassia alata leaf extract], Hyalufix GL [INCI: Alpinia Galanga leaf extract], Neurobiox [INCI: Achillea Millefolium extract], Deliner [INCI: Zea Mays (corn) seed extract], Lys'lastine V [INCI: Peucedanum Graveolens (Dill) Extract], Extracellium [INCI: Hydrolyzed Potato Protein], Proteasyl TP LS 8657 [INCI: Pisum Sativum Extract], FlavagrumPEG [INCI: PEG-6 isostearate, hesperetin laurate], Micromerol [INCI: Pyrus Malus fruit extract], Extracellium [INCI: Hydrolyzed potato protein], Marine Filling Spheres [INCI: Pentaerythrityl tetraisostearate, dimethylsilylated silica, sodium chondroitin sulfate, atelocollagen], Triactigen [INCI: Mannitol, cyclodextrin, yeast extract, disodium succinate], Eterniskin [INCI: Grifola Frondosa fruiting body extract, maltodextrin], Ascotide [INCI: Ascorbyl succinoyl pentapeptide-12 phosphate], Hyalurosmooth [INCI: Cassia Angustifolia seed polysaccharide], Indinyl CA [INCI: Cassia Angustifolia seed polysaccharide], Arganyl [INCI: Argania Spinosa leaf extract, Sphingoceryl Veg [INCI: plant ceramide], Vit-A-Like [INCI: Vigna Acontifolia seed extract], Peptiskin [INCI: arginine / lysine polypeptide], Prodejine [INCI: mannitol, cyclodextrin, yeast extract, disodium succinate], Aqu'activ [INCI: behenyl alcohol, glyceryl oleate, cocamide MIPA, calcium citrate], Elestan [INCI: glycerin, Manilkara leaf extract], Hibiscin HP [INCI: Hibiscus Esculentus seed extract], Collalift (registered trademark) 18 [INCI: Khaya Senegalensis peel], Collrepair (trademark) DG [INCI: hexylene glycol, niacin], or Litchiderm [INCI: Litchi Chinensis]Pericarp extract]; commercially available from Lipotec / Lubrizol: Argireline(registered trademark) [INCI: Acetyl hexapeptide-8], Argireline(registered trademark) Amplified [INCI: Acetyl hexapeptide-8], SNAP-7 [INCI: Acetyl heptapeptide-4], SNAP-8 [INCI: Acetyl octapeptide-3], Leuphasyl(registered trademark) [INCI: Pentapeptide-18], Inyline(registered trademark) [INCI: Acetyl hexapeptide-30], Aldenine(registered trademark) [INCI: Hydrolyzed wheat extract] [Protein, Hydrolyzed Soy Protein, Tripeptide-1], Preventhelia (Registered Trademark) [INCI: Diaminopropionoyl Tripeptide-33], Decorinyl (Registered Trademark) [INCI: Tripeptide-10 Citrulline], Decorinol (Registered Trademark) [INCI: Tripeptide-9 Citrulline], Trylagen (Registered Trademark) [INCI: Pseudoalteromonas Ferment Extract, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Tripeptide-10 Citrulline, Tripeptide-1], Eyeseryl (Registered Trademark) [INCI: Acetyl Tetrapeptide-5], PeptideAC29 [INCI: Acetyl Tripeptide-30 Citrulline], Relistase (Registered Trademark) [INCI: Acetyl Arginyl Tryptophyllid Diphenylglycine], Thermostressine (Registered Trademark) [INCI: Acetyl Tetrapeptide-22], Lipochroman (Trademark) [INCI: Dimethyl Methoxychromanol], Chromabright (Registered Trademark) [INCI: Dimethyl Methoxychromanyl Palminate], Antarcticine (Registered Trademark) [INCI: Pseudoalteromonas [Yeast extract], dGlyage (registered trademark) [INCI: Lysine HCl, Lecithin, Tripeptide-9 Citrulline], Vilastene (trademark) [INCI: Lysine HCl, Lecithin, Tripeptide-10 Citrulline], Hyadisine (registered trademark) [INCI: Pseudoalteromonas fermented extract], Hyanify (trademark) [INCI: Saccharide isomerate], Diffuporine (registered trademark) [INCI: Acetyl hexapeptide-37], Silusyne (registered trademark) [INCI: Soy (Glycine)Soja oil, sorbitan sesquioleate, isohexadecane, sodium hyaluronate, lauryldimonium hydroxypropyl hydrolyzed soy protein, acetyl hexapeptide-39, Adifyline (registered trademark) [INCI: acetyl hexapeptide-38], Delisens (trademark) [INCI: acetyl hexapeptide-46], Telangyn (trademark) [INCI: acetyl tetrapeptide-40], Reproage (trademark) peptide [INCI: acetyl hexapeptide-8], Cellynkage (trademark) marine ingredient [INCI: saccharin] [Lide isomerate], Eyedeline (trademark) marine component [INCI: plankton extract], uplevity (trademark) [INCI: acetyl tetrapeptide-2], Seacode (trademark) marine component [INCI: Pseudoalteromonas ferment extract], or Serilesine (registered trademark) peptide solution [INCI: hexapeptide-10]; commercially available from Lipotrue, Sirtalice (trademark) [INCI: Bacillus ferment], Epitensive (trademark) [INCI: Benthamiana tobacco hexapeptide-40 SH-oligopeptide-1], Scelleye (trademark) [INCI: Benthamiana tobacco SH-oligopeptide-2], Seadermium [INCI: aqua, glycerin, Bacillus ferment], Pauseile [I NCI: Aqua, Glycerin, Bacillus Ferment, or Neoclair pro [INCI: Aqua, Glycerin, Caprylyl Glycol, Acetyl Tetrapeptide-2]; commercially available from Vincience / ISP / Ashland: Collaxyl(Registered Trademark) IS [INCI: Hexapeptide-9], Laminixyl IS(Trademark) [INCI: Heptapeptide], Orsirtine(Trademark) GL [INCI: Oryza sativa (rice) extract], D'Orientine(Trademark) IS [INCI: Phoenix dactylifera (date palm) seed extract], Phytoquintescine(Trademark) [INCI: Einkorn (yellow wheat) extract], Quintescine(Trademark) IS [INCI: Dipeptide-4], Peptide Vinci 01 [INCI: Pentadecapeptide-1], Peptide Vinci 02 (trademark) [INCI: Hexapeptide-3], Aquarize IS (trademark) [INCI: Hydrolyzed Rice Extract], Lanablue [INCI: Algae Extract], Ederline (trademark) [INCI: Pyrus Malus (Apple) Seed Extract], Dynachondrine (trademark) ISR [INCI: Hydrolyzed Soy Protein], Prolixir S20 (trademark) [INCI: Dimer Tripeptide-43], Phytocohesine (trademark) PSP [INCI: Beta-Sitosteryl Sulfate Sodium, Beta-Sitosterol], Perenityl (trademark) IS [INCI: Pyrus Communis (Pear) Seed Extract], Caspaline 14 (trademark) [INCI: Hexapeptide-42], Peptide Q10 (trademark) [INCI: Pentapeptide-34 Trifluoroacetate], Survixyl IS (trademark) [INCI: Pentapeptide-31], ChroNOgen (trademark) [INCI: Tetrapeptide-26], Elixiance [INCI: Schinus Molle extract], Harmoniance (trademark) [INCI: Nelumbo Nucifera flower extract], Serenityl [INCI: Marsdenia Condurango peel extract], NatrianceWrinkle-less [INCI: Hydrolyzed Corn Protein], Phytoneomatrix [INCI: Hydrolyzed Soy Extract], Prolixir ICE [INCI: Hydrolyzed Rice Protein], PhytoRNx Baobab (Trademark) [INCI: Hydrolyzed Adansonia Digitata Extract], Natriance Renovate Extract [INCI: Hydrolyzed Flaxseed Extract], Natriance Autohydrate Extract [INCI: Pisum Sativum Extract], Actopontine YST [INCI: Hydrolyzed Yeast Protein], or Telosense (Trademark) [Proposed INCI: Hydrolyzed Soy Protein, Hydrolyzed Yeast Protein]; BONT-L-Peptide [INCI: Palmitoyl Hexapeptide-19], TIMP Peptide [INCI: Acetyl Hexapeptide-20], ECM, all marketed by Infinitec Activos. Moduline [INCI: Palmitoyl Tripeptide-28], Renaissance [INCI: Hydrolyzed Wheat Protein, Palmitoyl Decapeptide-21, Decapeptide-22, Oligopeptide-78, Zinc Palmitoyl Nonapeptide-14], or X50 Antiaging [INCI: Lactic Acid / Glycolic Acid Copolymer, Polyvinyl Alcohol, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate]; Commercially available from Coletica / Engelhard / BASF, EquiStat [INCI: Pyrus Malus Fruit Extract, Glycine Soja seed extract], Juvenesce [INCI: Ethoxydiglycol and caprylic triglyceride, retinol, ursolic acid, phytonadione, iromat], Ursolisome [INCI: Lecithin, ursolic acid, atelocollagen, xanthan gum, sodium chondroitin sulfate], Basaline [INCI: Hydrolyzed malt extract], Phytokine [INCI: Hydrolyzed soy protein]; Ameliox [INCI: Carnosine, tocopherol, Silybum marianum fruit extract], or PhytoCellTec Malus Domestica [INCI: Malus], all commercially available from Mibelle Biochemistr.The following can be selected: domestica fruit cell culture, Lipobelle soyaglicane [INCI: soy isoflavone], RoyalEpigen P5 [INCI: Butyrospermum Parkii butter, hydrogenated lecithin, maltodextrin, pentapeptide-48, phenethyl alcohol, ethylhexylglycerin, glycerin, aqua], or DermCom [INCI: Crocus Chrysanthus bulb extract, Acacia Senegal gum, aqua / water]; ActiMatrix [INCI: peptide-based mushroom extract], Peptamide 6 [INCI: hexapeptide-11], sold by Active Organics / Arch; and combinations thereof.

[0109] Tightening agents, skin elasticity enhancers, and / or reconstructors are marketed by BASF as Argassential [INCI: C10-16 alkyl glucoside, dicaprylyl ether, glycerin] or Replexium BC [INCI: dimethyl isosorbide, polysorbate 20, aqua, acetyl tetrapeptide-11, acetyl tetrapeptide-9]; marketed by Sederma / Croda as Prolevis [INCI: hydrolyzed vegetable protein] or Poretect [INCI: caprylic / capric triglyceride, sorbitan trioleate, Apium Graveolens seed extract, Linum Usitatissimum seed extract]; marketed by Lipotec / Lubrizol as Actifirm Ultra advanced botanical ingredients [INCI: Centella Asiatica extract, Rosmarinus Officinalis leaf extract, dipropylene glycol, alcohol, Echinacea]. The following can be selected: Angustifolia leaf extract, or Actifcol advanced plant components [INCI: aqua, glycerin, sodium citrate, Lentinus Edodes extract, potassium sorbate, sodium benzoate, phytic acid]; Densorphin (trademark) [INCI: Vitex Agnus Castus extract, aqua, maltodextrin] or PhytoCellTec (trademark) nunatak (registered trademark) [INCI: isomalt, aqua, Saponaria Pumila Callus culture extract, lecithin], sold by Mibelle; and combinations thereof.

[0110] The moisturizers include: qua Shuttle [INCI: sorbitol, Laminaria digita extract, diatomaceous earth], marketed by Infinitec; Aqua-Osmoline (trademark) [INCI: Ceratonia siliqua (locust bean) seed extract], marketed by Vincience / ISP / Ashland; and Hydralphatine (trademark) Asia [INCI: hydrogenated starch hydrolysate, panthenol, Bambusa vulgaris shoot extract, Nelumbo nucifera flower extract, Nymphaea], marketed by Lucas Meyer Cosmetics / Unipex. Alba root extract], or Hydraporine (trademark) [INCI: betaine, hydrogenated lecithin, honey, pectin]; PatcH2O (trademark) [INCI: trehalose, urea, serine, glyceryl polyacrylate, algin, sodium hyaluronate, pullulan], marketed by L.Serobiologiques / Cognis / BASF, Aqu'activ (trademark) [INCI: behenyl alcohol, glyceryl oleate, cocamide MIPA], Irwinol (registered trademark) [INCI: octyldodecanol, Irvingia] Gabonensis kernel butter, hydrogenated coco-glycerides, Lipodermol (registered trademark) [INCI: octyldodecanol, arachidyl propionate, tocopheryl acetate, retinyl palmitate, ethyl linoleate, ethyl linolenate], or Seanamin (registered trademark) SU [INCI: sorbitol, algal extract, Chrondrus Crispus (carrageenan), Fucus Vesiculosus extract, algin]; Snow ice algae powder [INCI: Coenochloris Signiensis extract], marketed by Mibelle; Hyasol BT [INCI: sodium hyaluronate], Syn-Up (trademark) [INCI: benzylsulfonyl D-ceryl homophenylalanine amidinobenzamide acetate], marketed by Pentapharm / DSM, or Pentavitin (registered trademark) [INCI: saccharide isomerate];Commercially available from Sederma / Croda: Aqualance (trademark) [INCI: erythritol, fomarin HCl], Hydraprotectol (trademark) [INCI: polyglyceryl methacrylate, aloylitic acid, yeast extract (Faex), glycoprotein], Moist 24 (trademark) [INCI: Imperata Cylindrica root extract], Optim The following can be selected from the group consisting of Hyal (trademark) [INCI: hydrolyzed yeast extract, cetyl hydroxyethylcellulose, polyglucuronic acid], Osmocide (registered trademark) 4 [INCI: glycerin, acrylic acid / C10-30 alkyl acrylate crosspolymer], or Revidrate (trademark) [INCI: ethylhexyl palmitate, sorbitan oleate, sorbitan laureate, myristylphosphonic acid malate]; Xpertmoist (registered trademark) molecular film [INCI: glycerin, Pseudoalteromonas ferment extract, xanthan gum, proline, alanine, serine, ethylhexylglycerin, caprylyl glycol], sold by Lipotec / Lubrizol; or Actizyme GL advanced plant ingredients [INCI: glycerin, Mucor miehei extract, aqua, sodium citrate, potassium sorbate, sodium benzoate, phytic acid]; and combinations thereof.

[0111] Photoaging inhibitors and / or blue light protectants include Algaktiv Genofix CPD [INCI: Plankton Extract, Aqua, Lecithin], marketed by Greenaltech; Blumilight (Trademark) Biofunctional [Proposed INCI: Water / Aqua (and) Butylene Glycol (and) Theobroma Cacao (Cocoa) [Seed Extract]], marketed by Ashland; Lys'Sun [INCI: Hamamelis Virginiana Leaf Extract, Aqua, Pentylene Glycol, Caprylyl Glycol, Xanthan Gum], marketed by BASF; Vitachelox [INCI: Vitis Vinifera Seed Extract, Camellia Sinensis Leaf Extract, Quercus Robur Wood Extract], marketed by Indena; and Freshine. L-VCG [INCI: Ascorbyl Glucoside], marketed by Bio-technology; Lumicease® Blue Component [INCI: Glycerin, Aqua, Hydrolyzed Pea Protein, Glucose, Sodium Chloride], marketed by Lipotec / Lubrizol; Lightwaves Defense [INCI: Jasminum Sambac Leaf Cell Extract], marketed by Naolys; Blue Oleoactif [INCI: Glycine Soja Oil, Polyglyceryl-3 Diisostearate, Oryza Sativa Germ Extract, Oryza Sativa Extract], marketed by Oleos-Hallstar; Majestem [INCI: Leontopodium Alpinum Callus Culture Extract, Xanthan Gum] or Senestem [INCI: Glycerin, Plantago Lanceolata Leaf Extract, Xanthan Gum], marketed by Sederma; Blueshield [INCI: Glycerin, Capsicum], marketed by Solabias Annuum fruit extract, xanthan gum; and combinations thereof can be selected from this group.

[0112] DNA protectants, DNA repair agents, and / or stem cell protectants are commercially available from Vincience / ISP / Ashland, including GP4G SP [INCI: Aqua, Glycerin, Aretmia Extract], Heliostatine [INCI: Aqua, Glycerin, Pisum Sativum Extract], Orsirtine [INCI: Aqua, Glycerin, Oryza Sativa Extract], Chronogen [INCI: Aqua, Butylene Glycol, Tetrapeptide (Proposed INCI)], Survixyl IS [INCI: Water, Butylene Glycol, Pentapeptide-31], and Chrondricare [INCI: Aqua, Butylene Glycol, Pentapeptide-28]; and Lanacityn® [INCI: Glycerin, Aqua, Alteromonas Ferment Extract, Chysanthellum], commercially available from Atrium Innovations / Lucas Meyer Cosmetics. [Indicum extract] or Melinoil [INCI: Isopropyl palmitate, lecithin, aqua, acetyl hexapeptide-1]; commercially available from CLR; Repair complex [INCI: Bifida fermentation lysate]; commercially available from Codif; Phycojuvenine [INCI: Laminaria digita]; sold by Induchem; Unirepair T-43 [INCI: Butylene glycol, acetyl tyrosine, proline, hydrolyzed vegetable protein, adenosine triphosphate]; commercially available from Symrise; Dragosine [INCI: Carnosine]; commercially available from Laboratories Serobiologiques / Cognis / BASF; DN-Age [INCI: Cassia alata leaf extract];Commercially available from Mibelle Biochemistry are Helioguard [INCI: Porphyra Umbilicalis encapsulated in liposomes], PhytoCellTec Malus Domestica [INCI: PhytoCellTec Malus Domestica], or PhytoCellTec Argan [INCI: Argania Spinosa Sprout cell extract, isomalt, lecithin, sodium benzoate, aqua]; sold by Pentapharm / DSM is Pepha-Protect [INCI: watermelon extract]; and commercially available from Rahn are Celligent [INCI: Helianthus Annuus seed oil, ethyl ferulate, polyglyceryl-5 trioleate, Rosmarinus Officinalis leaf extract, aqua, disodium uridine phosphate], or Defensil [INCI: octyldodecanol, Echium Plantagineum seed oil, Cardiospermum Halicacabum extract, Helianthus [Annuus seed oil unsaponifiables]; Venuceane [INCI: Thermus Thermophilus ferment, glycerin], UV-Soft [INCI: Yeast extract], Renovage [INCI: Caprylic / capric triglyceride, teprenone], Juvinity [INCI: Caprylic / capric triglyceride, geranylgeranylpropanol (suggested)], Phytessence Holyherb [INCI: Butylene glycol, Eriodictyon Californicum (Holyherb) flower / leaf / stem extract], or Resistem [INCI: Glycerin, Globularia Cordifolia ferment]; Infraguard [INCI: Caesalpinia Spinosa fruit pod extract, propylene glycol, aqua, Helianthus Annuus bud extract, sodium benzoate, phenoxyethanol], commercially available from Mibelle;The following can be selected from the group consisting of Heliomoduline [INCI: low molecular weight peptide from cotton] or Stem-C-Guard [hydrolyzed pea], both commercially available from Silab, and combinations thereof.

[0113] Reactive carbonyl species scavengers, free radical scavengers, and / or anti-glycation agents, detoxifiers, antioxidants, and / or anti-pollution agents include, for example, but are not limited to, carnosine and its derivatives; GHK [INCI: tripeptide-1], and its salts and / or derivatives, commercially available from Vincience / ISP / Ashland; or Quintescine IS [INCI: dipeptide-4]; Preregen [INCI: Glycine Soja (soybean) protein, oxidoreductase], Edelweiss GC [INCI: Leontopodium Alpinum extract], Lipogard [INCI: squalane, ubiquinone], Nectapure [INCI: Buddleja Davidii extract, Thymus Vulgaris extract], Alpaflor Nectapure [INCI: Buddleja Davidii extract, Thymus Vulgaris extract]. Vulgaris extract, glycerin, water], or Dismutin-BT [INCI: SOD highly purified from natural yeast strain of Saccharomyces cerevisiae]; Preventhelia (registered trademark) [INCI: diaminopropionoyl tripeptide-33], Aldenine (registered trademark) [INCI: hydrolyzed wheat protein, hydrolyzed soy protein, tripeptide-1], Lipotec / Lubrizol-marketed ingredients, Lipochroman (trademark) [INCI: dimethylmethoxychromanol], Thermostressine (registered trademark) [INCI: acetyl tetrapeptide-22], Pollushield (trademark) functional ingredients [INCI: diisopropyl adipate, lecithin, acrylic acid / acrylamide methylpropanesulfonic acid copolymer, dimethylmethoxychromanol, xanthan gum], or Bodyfensine (registered trademark) [INCI: acetyl dipeptide-3 aminohexanoate];unactyl [INCI: mannitol, Pisum Sativum extract, histidine HCl, arginine, cyclodextrin, dextrin, yeast extract, acetyltrypsin, pyridoxine HCl, Khaya Senegalensis peel extract, nicotinamide, adenine dinucleotide, disodium succinate, aspartic acid], Imidinyl [INCI: Tamarindus Indica seed polysaccharide], Phystrogene [INCI: butylene glycol, Malva Sylvestris (mallow) extract, xanthan gum], or Purisoft [INCI: Moringa Pterogysperma seed extract], all commercially available from Laboratoires Serobiologiques / Cognis / BASF; AquaCacteen [INCI: glycerin, Opuntia Ficus], all commercially available from Mibelle Biochemistry. Indica stem extract, phenoxyethanol, aqua], Trimoist (KMF) [INCI: Sodium stearoyl lactylate, cetyl alcohol, Olus vegetable oil, tocopheryl acetate, glycerin, Glycine soja sterol, sodium lactate, barboxymethyl beta-glucan sodium, carnosine, lactic acid], MelanoBronze [INCI: Vitex Agnus Castus extract (monk pepper fruit extract (phytoendorphin)), acetyl tyrosine], CM-glucan [INCI: Sodium carboxymethyl beta-glucan sodium, phenoxyethanol, SunActin [INCI: Helianthus Annuus (sunflower) sprout extract], tocopherol, glycerin, lecithin, phenoxyethanol, aqua], GSP-T skin [INCI: Glycerin, alcohol, aqua, PEG-40 hydrogenated castor oil, Vitis Vinifera (grape) seed extract, or Detoxophane [INCI: Lepidium Sativum bud extract, lecithin, phenoxyethanol, glycerin, water];Bacocalmine [INCI: PEG-8, Bacopa Monniera extract, water (aqua), hydroxyethylcellulose], Kombuchka [INCI: Saccharomyces / Xylinum black tea ferment, glycerin, hydroxyethylcellulose], Citystem [INCI: glycerin, Marrubium Vulgare extract], or Prodizia [INCI: Albizia Julibrissin extract, glycerin], sold by Sederma / Croda; Extramel C [INCI: hydroxypropyltrimonium maltodextrin crosspolymer, Cucumis Melo (melon)] fruit extract, sold by Seppic; Defensine [INCI: Triticum Vulgare germ extract], Apolluskin® [INCI: Taraxacum officinale (dandelion) extract], Detoxyl® [INCI: water, butylene glycol, Butyrospermum], sold by Silab [Shea Parkii (shea butter) seed cake extract], or Antiglyskin [INCI: Aqua, Helianthus Annuus seed extract; and combinations thereof can be selected from the group formed therefrom.]

[0114] Personal care formulations may contain agents that increase the transdermal absorption of any active compounds present therein. Such agents include, but are not limited to, dimethyl sulfoxide, dimethylacetamide, dimethylformamide, surfactants, azone (1-dodecyl azacycloheptan-2-one), alcohol, urea, ethoxydiglycol, acetone, propylene glycol, or polyethylene glycol.

[0115] The personal care formulation according to the present invention is also suitable for sunscreen or sun care products. Therefore, the personal care formulation may contain ingredients typically used for sunscreen purposes. Non-limiting examples include: benzoic acid derivatives, para-aminobenzoic acid (PABA), especially monoglycerol esters of PABA, ethyl esters of N,N-propoxy PABA, ethyl esters of N,N-diethoxy PABA, ethyl esters of N,N-dimethyl PABA, methyl esters, butyl esters of N,N-dimethyl PABA, anthranilic acid derivatives such as homomenthyl-N-acetyl anthranilate; amyl salicylate, homomenthyl salicylate, ethylhexyl salicylate, phenyl salicylate, benzyl salicylate (salicy Salicylic acid derivatives such as p-isopropanolphenyl cinnamate; ethylhexyl cinnamate, ethyl-4-isopropyl cinnamate, methyl-2,5-diisopropyl cinnamate, p-methoxypropyl cinnamate, p-methoxyisopropyl cinnamate, p-methylisoamyl cinnamate, p-methoxyoctyl cinnamate, p-methoxy-2-ethylhexyl cinnamic acid, p-methoxy-2-ethoxyethyl cinnamic acid, p-methoxycyclohexyl cinnamic acid, ethyl-o-cyano-3-phenyl cinnamate, 2-ethylhexyl cinnamic acid-o-ethylhexyl cinnamic acid Cinnamic acid derivatives such as cyano-3-phenyl and glyceryl cinnamate diparamethoxymono-2-ethylhexanoyl; a family of benzophenone derivatives such as 2,4-dihydroxybenzophenone, 2,2'-dihydroxy-4-methoxybenzophenone, 2,2',4,4'-tetrahydroxybenzophenone, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, (2-ethylhexyl)-4'-phenylbenzophenone-2-carboxylate, 2-hydroxy-4-(n-octyloxy)benzophenone, and 4-hydroxy-3-carboxybenzophenone; 3-(4'-methylbenzylidene)d,l-camphor, 3-(benzylidene)d,l-camphor, and benzalkonium methosulfate camphor;Urocanic acid, ethyl urocanate; sulfonic acid derivatives such as 2-phenylbenzimidazole-5 sulfonic acid and its salts; hydroxyphenyl triazine, (ethylhexyloxy)(hydroxyphenyl)(4-methoxyphenyl) triazine, 2,4,6-trianilino-(p-carbo-2'-ethylhexyl-1'-oxy)-1,3,5-triazine, 4,4-((6-((((1,1-dimethylethyl)amino)carbonyl)phenyl)amino)-1,3,5-triazine-2,4-diyldiimino)bis(2-ethylhexyl) ester of benzoic acid, 2-phenyl-5-methylbenzoxazole, 2-(2'-hydroxy-5'-methylphenyl)benzotriazole, 2-(2'-hydroxy-5' Examples include the family of triazine derivatives such as -t-octylphenyl)benzotriazole and 2-(2'-hydroxy-5'-methylphenyl)benzotriazole; dibenzazine; dianisioylmethane, 4-methoxy-4"-t-butylbenzoylmethane; 5-(3,3-dimethyl2-norbornylidene)-3-pentan-2-one; diphenylacrylic acid derivatives such as (2-ethylhexyl)2-cyano3,3-diphenyl2-propenoate and ethyl-2-cyano3,3-diphenyl2-propenoate; polysiloxanes such as benzylidenesiloxane malonate; and inorganic solar filters, also known as "mineral screens," made from titanium dioxide, zinc oxide, cerium oxide, zirconium oxide, yellow, red, or black iron oxides, and chromium oxide.

[0116] The personal care formulations of the present invention may include, but are not limited to, alkali silicate, zinc sulfate, zinc gluconate, zinc chloride, zinc lactate, and other zinc salts; quaternary ammonium salts, such as cetyltrimethylammonium salt and cetylpyridinium salt; sodium bicarbonate; cyclodextrin; metal zeolites; and deodorants such as aluminum hydrobromide, aluminum hydrochloride, aluminum chloride, aluminum sulfate, aluminum hydrochloride and zirconium, aluminum hydrochloride and zirconium, aluminum tetrachloride and zirconium, aluminum pentachloride and zirconium, aluminum octachloride and zirconium, aluminum sulfate, sodium lactate and aluminum; aluminum hydrochloride and glycol complexes, such as aluminum hydrochloride and propylene glycol, aluminum dihydrochloride and propylene glycol complexes, aluminum sesquichloride and propylene glycol complexes, aluminum hydrochloride and polyethylene glycol complexes, aluminum dihydrochloride complex and polyethylene glycol, and complexes of aluminum sesquichloride and polyethylene glycol.

[0117] The personal care formulations of the present invention may include, for example, but are not limited to, film-forming components such as chitosan, microcrystalline chitosan, quaternary chitosan, polyvinylpyrrolidone, vinylpyrrolidone / vinyl acetate copolymer, acrylic acid polymers, quaternary cellulose derivatives, collagen, hyaluronic acid and its salts, and similar compounds.

[0118] The personal care formulation of the present invention may include, for example, but not limited to, insect repellents such as N,N-diethyl-m-toluamide, pentane-1,2-diol, ethyl butylacetylaminopropionate, essential oils, and similar compounds.

[0119] The present invention will be explained by the following non-limiting embodiments. [Examples]

[0120] Example 1 Stability of emulsions containing MCC and natural gum To test the effectiveness of natural polymer emulsifiers, different emulsions were prepared by combining MCC, NaCMC, and / or natural gum. Phenoxyethanol, MCC, NaCMC, and natural gum were added to water, and then the oil phase was slowly added to the aqueous phase under stirring.

[0121] Subsequently, the shear force was increased to 10,000 rpm for 1 minute using an ultra-turrax. The pH was adjusted to 5.5. This process was carried out under both low-temperature and high-temperature conditions (heated to 70°C during the emulsification process).

[0122] [Table 1]

[0123] [Table 2]

[0124] Viscosity was measured at 25°C using a Brookfield LVT viscometer with an appropriate spindle depending on the emulsion viscosity. The emulsion was tested at 20 rpm, and viscosity was determined 24 hours after emulsion preparation. Results are shown in mPa·s.

[0125] The yield value is generally defined as the initial resistance to flow under applied stress. In the case of Bingham and Ellis plastic flow, a minimum shear stress is required to initiate flow. This minimum stress is known as the yield value or yield index. Yield is measured by the Brookfield-Viscomet method, which determines the viscosity at 0.5 and 1 rpm at 25°C. The Brookfield yield value is calculated as Brookfield yield value = (apparent viscosity at 0.5 rpm - apparent viscosity at 1 rpm) / 100, and is expressed as dyn / cm 2 It is measured at [location / location].

[0126] Cohesion is a measure of emulsion stability. Cohesion is measured by visual inspection, and the result is a value from 0 to 5 (5 being the best result with no cohesion, and 0 being the worst result with complete phase separation). A value of 0 represents the appearance of a thick film layer of oil on the surface (i.e., a broken emulsion). 1 indicates a slight film layer, 2 indicates oil retention, 3 indicates numerous small and large droplets, 4 indicates a few small droplets, and 5 indicates no visible droplets.

[0127] In Tables 1 and 2 above, "fail" means the emulsion was not stable at 50°C after one month, and "pass" means it was stable at 50°C after one month.

[0128] The results show a remarkable synergistic effect between MCC and diutan gum when combined with NaCMC, both in terms of viscosity and yield. Furthermore, the emulsion stability is higher, as emulsions containing a mixture of MCC, NaCMC, and diutan gum yielded better results in bonding after 24 hours at 50°C for higher viscosity and yield. None of the other natural gums provided satisfactory results, as they were not stable after a period of one month at 50°C.

[0129] Example 2 Determination of polymer ratio and the effect of concentration O / W emulsions were prepared as in Example 1, but components at different concentrations were tested.

[0130] [Table 3]

[0131] Emulsions with three or more compounding results were considered to be the best-performing emulsions. Based on the same component ratios as the best-performing emulsions, the effects of the total concentrations of diutane, MCC, and NaCMC were tested.

[0132] [Table 4]

[0133] The higher the total concentration of the combination, the higher the viscosity at both room temperature and 50°C. Regarding the combination, the optimal concentration of the emulsifier composition containing dieutan gum, MCC, and NaCMC was 0.7% by weight, based on the total weight of the composition.

[0134] Example 3 surface tension measurement A batch of 600 grams of water containing either dieutan gum or MCC in combination with 0.01% by weight of NaCMC was prepared in an 800 mL beaker using a 2-inch marine blade. The batch was mixed at 300 rpm for 1 hour (to avoid splashing).

[0135] Viscosity was recorded 24 hours later using a Brookfield viscometer and spindle #1. The sample was run on a Kruss tensiometer for 60 minutes, with data points taken every 30 seconds.

[0136] The definition of "surfactant" is found in the World Customs Organization's notes, which can be found in the chapter notes of Chapter 34 of the Customs Act. Under heading 34.02 of the relevant chapter, "organic surfactants" are defined as those that, when mixed with water at a concentration of 0.5 percent at 20°C and left standing at the same temperature for 1 hour, (a) Provide a clear or translucent liquid or a stable emulsion without separating insoluble matter, (b) A product that reduces the surface tension of water to 45 mN / m (45 dyne / cm) or less.

[0137] The surface tension is obtained as follows: The concentration of 0.01% by weight of diutan gum in water was 62.069 mN / m, and the first value was 57.51 mN / m. The MCC+CMC concentration of 0.01 wt% was 60.033 mN / m, and the first value was 52.56 mN / m.

[0138] Because their surface tension was higher than 45 mN / m, these components were not considered as surfactants.

[0139] Example 4 Co-emulsifier effect The effect of co-emulsifiers was investigated. Glyceryl caprylate and polyglyceryl-3 laurate were each added to the emulsion in an amount of 0.5% by weight. In both cases, there was a slight increase in emulsion stability, particularly with polyglyceryl-3 laurate (giving an emulsion with a co-emulsification value of 5 after 4 weeks at 50°C). When each co-emulsifier was used alone in the emulsion, i.e., in the absence of MCC, NaCMC, and dieutan gum, complete separation occurred after 24 hours. This indicates that the use of at least MCC and dieutan gum is essential for good stability.

[0140] [Table 5]

[0141] Example 5 Shear impact in polymer properties The effects of shear were investigated. Some polymers are affected by shear by losing some of their properties. For this reason, it is important to understand whether the application of shear can alter the properties of the emulsifier composition of the present invention. A viscous mixture containing 0.2 wt% dieutan gum, 0.42 wt% MCC, and 0.08 wt% CMC was stirred at different speeds for 10 minutes using an ultraturrax. Viscosity and yield were measured after 24 hours, and the results are shown in this table.

[0142] [Table 6]

[0143] Shearing does not affect the effectiveness of the emulsifier system of the present invention in any way.

[0144] Example 6 pH compatibility Different emulsions were prepared at different pH levels, and their properties were analyzed.

[0145] [Table 7]

[0146] The emulsion was stable at all pH levels after 24 hours, and yielding decreased slightly as the pH increased.

[0147] Example 7 Increased viscosity The addition of starch derivatives to increase emulsion viscosity was also investigated. A drawback of biopolymers is that they do not provide a thick emulsion. A thick emulsion is necessary to obtain a gel cream or cream product.

[0148] As detailed below, four formulations labeled A, B, C, and D were prepared, and the viscosity and yield of each formulation were measured.

[0149] [Table 8]

[0150] The addition of starch derivatives allows for the preparation of gel-cream emulsions or cream emulsions, but in the absence of starch derivatives, only fluid emulsions (lotions) are obtained.

[0151] Example 8 Performance in high-oil O / W emulsions O / W emulsions were prepared using emulsifiers and oils of different concentrations. The emulsion compositions were as follows:

[0152] [Table 9]

[0153] Table 10 summarizes the viscosity results in mPa·s of the formulations after 24 hours at 25°C and 20 rpm.

[0154] [Table 10]

[0155] The emulsifier containing MCC + NaCMC + dieutan gum exhibits low viscosity and good stability at all tested concentrations, including high concentrations of oil. Good stability means that the viscosity does not differ by more than 30% compared to the initial time, the pH does not differ by more than 1 point, and the compounding ratio is acceptable (greater than 3 on a scale of 0 to 5).

[0156] Example 9 Stability over time at different pH values An emulsion containing the following components was prepared.

[0157] [Table 11]

[0158] Citric acid was added to adjust the pH to a range of 3-6, and sodium hydroxide was added to adjust the pH to 7 or 8.

[0159] The viscosity results are summarized below.

[0160] [Table 12]

[0161] After one month at 50°C, the viscosity was maintained within a very small fluctuation range of less than 30%, the pH did not differ by more than 1 point, and the compounding ratio was acceptable (greater than 3 over a range of 0-5), allowing compounders to work with different pH levels.

[0162] Example 10 Ethanol resistance The use of ethanol in cosmetic products is common because it provides consumers with a fresh feeling, speeds up drying time, and allows for faster absorption of the product on the skin. Nevertheless, some natural ingredients are not tolerant to ethanol.

[0163] The following formulations containing ethanol were prepared, and their viscosity was determined at 20 rpm.

[0164] [Table 13]

[0165] When an emulsifier containing MCC + NaCMC + dieutan gum was used, there were no significant changes in viscosity, pH, and compounding ratio, indicating that the emulsion was stable. In contrast, when tara gum was used, the viscosity was very high at 5% and 10% (w / w) ethanol concentrations, and the appearance of the gel at 10% ethanol was unsatisfactory.

[0166] Example 11 Purifying serum for oily skin In a clean beaker, mix the components of phase A together under stirring. Next, add B under stirring (dispersion blade) until a homogeneous blend is obtained. Next, C is prepared in a separate beaker and gradually added to the batch while stirring vigorously. Then, the emulsion is homogenized using a rotor stator at 10,000 rpm for 1 minute. Next, the components of phase D are added to the batch one by one under stirring.

[0167] [Table 14]

[0168] Example 12 Diaper rash lotion Mix the components of phase A in a clean beaker with stirring. Then, add B while stirring (using a dispersion blade) until homogenized. Next, add C to the batch under homogenization with a rotor stator until the pigment is completely dispersed. Next, prepare D in a separate beaker and add it little by little to the batch while stirring vigorously. Then, homogenize the emulsion using a rotor stator at 10,000 rpm for 1 minute. Finally, add phase E with stirring.

[0169] [Table 15]

[0170] Mix the components of phase A in a clean beaker under stirring. Next, add B under stirring (using a dispersion blade) until homogenized. Then, add C to the batch under homogenization with a rotor stator until the pigment is completely dispersed. Next, prepare D in a separate beaker and add it little by little to the batch while stirring vigorously, then homogenize the emulsion using a rotor stator at 10,000 rpm for 1 minute. Then, add phase E under stirring.

[0171] Example 13 Sun Care Lotion SPF50 Mix the components of phase A in a clean beaker while stirring.

[0172] Next, B is added under stirring (using a dispersion blade) while heating to 75°C until homogeneously dispersed. Then C is added to the batch. Next, D is prepared in a separate beaker by mixing the components together and heating to 75°C, and then D is added little by little to the batch under vigorous stirring. Subsequently, the emulsion is homogenized for 1 minute at 10,000 rpm using a rotor stator. Finally, the emulsion is cooled to 30°C under stirring in order to add E.

[0173] [Table 16]

Claims

1. a) 40-70% by weight of microcrystalline cellulose, b) 25–45% by weight of at least one biogum of microbial origin, c) comprising 8 to 12% by weight of at least one cellulose ether or its derivative, all weight percentages are based on the weight of the total composition. An emulsifier composition comprising at least one biogum of microbial origin containing sphinganexopolysaccharide.

2. The emulsifier composition according to claim 1, wherein the weight ratio of (a):(b):(c) is 2 to 8 (a), 1 to 20 (b), and (c) is 1.

3. The emulsifier composition according to claim 1, wherein the at least one cellulose ether or derivative thereof is selected from methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxyethylmethylcellulose, methylhydroxyethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, carboxymethylcellulose, sodium carboxymethylcellulose, and mixtures thereof.

4. The emulsifier composition according to claim 1, wherein the at least one biogum of microbial origin comprises dieutan gum.

5. The emulsifier composition according to claim 1, wherein the at least one cellulose ether or derivative thereof comprises sodium carboxymethylcellulose.

6. i) Aqueous phase and, ii) Oil phase and iii) A personal care formulation comprising the emulsifier composition according to any one of claims 1 to 5.

7. The personal care formulation according to claim 6, wherein the formulation is an emulsion and the aqueous phase is a continuous phase.

8. The personal care formulation according to claim 6, wherein the formulation is an emulsion and the oil phase is a continuous phase.

9. The personal care formulation according to claim 6, further comprising a personal care active ingredient, a pharmaceutical active ingredient, and a mixture thereof.

10. The personal care formulation according to claim 6, further comprising fatty alcohols, glyceryl caprylate, polyglyceryl-3 laurate, glyceryl stearate, glyceryl citrate stearate, cetearyl olivate, sorbitan olivate, sodium stearate or potassium stearate, sucrose, sucrose esters of fatty acids, lactate, and a coemulsifier selected from the group consisting of mixtures thereof.

11. The personal care formulation according to claim 6, further comprising a starch derivative.

12. The personal care formulation according to claim 6, wherein the emulsifier composition is present in an amount of 0.1 to 5% by weight based on the total weight of the composition.

13. The personal care formulation according to claim 6, wherein the oil phase is present in an amount of 5 to 50% by weight based on the total weight of the composition.

14. A method for preparing a personal care formulation as defined in claim 6, (i) Dispersing the emulsifier composition according to any one of claims 1 to 5 in an aqueous phase, (ii) Stirring the oil phase in the aqueous phase to form an emulsion, and optionally, (iii) A method comprising adjusting the pH of the emulsion to less than 7.

15. A method for stabilizing a composition comprising an oil phase and an aqueous phase, comprising the step of mixing the emulsifier composition according to any one of claims 1 to 5 with the oil phase and the aqueous phase.

16. Use of the composition according to any one of claims 1 to 5 for stabilizing an emulsion containing an oil phase and an aqueous phase.

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