Compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity

Abstract

The present invention relates to a compound of general formula I wherein Q is a group of formula Q1, Q2, Q3, Q4, Q5 or Q6 Z is H or OH; Y, G, M, O, R1, R2, R3, R4, are as defined; the compoound acting both as muscarinic receptor antagonist and beta2 adrenergic receptor agonist, to composition comprising them, to therapeutic use and combination with other pharmaceutical active ingredients among which are, for instance, those currently used in the treatment of respiratory disorders, e.g. corticosteroids, P38 MAP kinase inhibitors, IKK2, HNE inhibitors, PDE4 inhibitors, leukotriene modulators, NSAIDs and mucus regulator.