Therapeutic use of fibroblasts for adhesive bandage wound healing
By integrating non-live fibroblasts and fibroblast-derived materials into bandages, the limitations of traditional wound care are overcome, resulting in accelerated and improved wound healing through direct delivery of therapeutic agents.
WO2025058798A1 Publication Date: 2025-03-20FIBROBIOLOGICS INC
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Patent Information
- Application Number
- PCT/US2024/042875
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2023-09-15
- Filing Date
- 2024-08-19
- Publication Date
- 2025-03-20
AI Technical Summary
Technical Problem
Traditional bandages lack the ability to actively contribute to the wound healing process, failing to provide a sufficiently moist environment or additional therapeutic benefits.
Method used
Incorporating non-live fibroblasts and/or fibroblast-derived materials such as exosomes, lysates, membranes, apoptotic bodies, growth factors, cytokines, and chemokines onto a bandage to create an advanced wound care solution.
Benefits of technology
The use of fibroblast-containing bandages enhances wound healing by delivering therapeutic factors directly to the wound site, promoting faster tissue regeneration and improved wound closure.
✦ Generated by Eureka AI based on patent content.
Abstract
Embodiments of the disclosure include methods, compositions, and systems for wound care utilizing a wound coverage substrate utilizing dehydrated or lyophilized non-live fibroblasts and / or dehydrated or lyophilized fibroblast-derived materials. In particular embodiments, the wound coverage substrate comprises the dehydrated or lyophilized non-live fibroblasts and / or dehydrated or lyophilized fibroblast-derived materials and upon delivery to the wound, the moisture of the wound re-hydrates the dehydrated or lyophilized non-live fibroblasts and / or dehydrated or lyophilized fibroblast-derived materials.
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