Process for the purification of perfluoroalkyl acids

The described process for converting PFAS mixtures into isomerically pure n-isomers addresses the challenge of achieving high purity PFAS, facilitating accurate analysis and potentially reducing toxicity risks.

WO2025061960A1 Publication Date: 2025-03-27CHIRON AS
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Patent Information

Application Number
PCT/EP2024/076455
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-09-20
Filing Date
2024-09-20
Publication Date
2025-03-27

AI Technical Summary

Technical Problem

Current methods for purifying poly- and perfluoroalkyl acids (PFAS) fail to achieve isomerically pure compounds, leading to challenges in accurate quantification and potential differences in toxicity among isomers.

Method used

A process involving the conversion of PFAS mixtures into aryl esters or ammonium salts, followed by recrystallization and subsequent hydrogenation or acidification to obtain isomerically pure n-isomers of poly- and perfluoroalkyl sulfonic acids or carboxylic acids.

Benefits of technology

This process achieves isomerically pure PFAS with chromatographic purities of at least 97%, enabling accurate analysis and potentially reducing toxicity risks associated with impure isomers.

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Abstract

The present invention is directed to poly- and perfluoroalkyl sulfonic acids and poly- and perfluoroalkyl acids and processes for the purification and isolation of isomers from mixtures as well as highly pure poly- and perfluoroalkyl sulfonic acids and poly- and perfluoroalkyl acids and the corresponding uses.
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