Nebulization assistant device and nebulization system

Abstract

The present application relates to the technical field of nebulizer therapy, and in particular, to a nebulization assistant device and a nebulization system. The nebulization assistant device comprises an assistant respirator and an information processing module, and can be used in cooperation with an inhalation administration module for providing a patient with a drug for respiratory administration via nebulization, so as to constitute the nebulization system. The information processing module acquires a respiratory frequency of the patient on the basis of a time series of respiratory sounds collected by a respiratory sound collection unit, and determines a start time of an inflatable garment according to a matching condition between the respiratory frequency of the patient and a drug supply frequency of the inhalation administration module. On the basis of the correlation analysis between respiratory sound / lung sound signals collected by the assistant respirator and drug flow data, the information processing module generates an adjustment instruction regarding the nebulization position, respiratory mode, and / or nebulization drug proportions.

Description

Atomization auxiliary device and atomization system Technical Field

[0001] This invention relates to the field of nebulization therapy technology, and in particular to a nebulization auxiliary device and nebulization system. Background Technology

[0002] Nebulization therapy is an important clinical intervention in the fields of respiratory diseases and otolaryngology. The treatment process mainly involves core medical equipment such as jet nebulizers, ultrasonic nebulizers, and oxygen-driven nebulization systems. Current technologies suffer from delayed response times in nebulization parameter adjustment, typically requiring parameter correction only after clinical indications or adverse reactions have manifested. For pediatric patients, due to a mismatch between respiratory rhythm and equipment operating cycles, overdose of medication is often necessary to achieve the desired therapeutic effect.

[0003] In the prior art concerning respiratory rate and nebulized drug delivery frequency, CN116212177A discloses a nebulized drug delivery system and its control method. The control method includes: acquiring a respiratory signal detected by a respiratory sensor located on a first ventilation duct; determining the respiratory state through the respiratory signal; if the respiratory state is inhalation, adjusting the frequency of the nebulizing device in the nebulizer through the main unit of the nebulizer to control the nebulizing device to nebulize the stored drug and deliver the nebulized drug to the first ventilation duct; if the respiratory state is exhalation, adjusting the frequency of the nebulizing device through the main unit to control the nebulizing device to stop nebulizing the drug; acquiring the exhaled gas through a pulmonary function testing instrument located on a second ventilation duct and calculating the vital capacity parameter based on the gas.

[0004] The aforementioned disclosed technical solutions focus on respiratory synchronization control but lack a dynamic monitoring module for nebulization efficacy. While existing solutions can alleviate the problem of respiratory-nebulization airflow interference, they lack a real-time assessment mechanism for nebulization deposition efficiency and do not integrate multi-dimensional control parameters affecting nebulization delivery efficiency. Current clinical assessment systems generally suffer from time lag, typically requiring several days of observation combined with cough symptom scores and pulmonary function retesting to determine treatment effectiveness. There is an urgent need to develop a closed-loop management system that integrates real-time nebulization effect monitoring and intelligent control. Summary of the Invention

[0005] Existing technologies have developed solutions that adaptively adjust the oxygen supply flow rate and the nebulized drug delivery airflow rate based on the patient's respiratory rate and other physiological parameters to balance inhalation and exhalation volumes, ensuring adequate drug absorption. For example, CN116920229A discloses a nebulizer for elderly respiratory patients, including a nebulizing mask, an oxygen source, a nebulizer, a gas supply chamber, a respiratory monitoring instrument, and a controller. One side of the nebulizer is connected to a high-pressure air pump to disperse the solution contained within through the input airflow, and the other side is connected to a spray valve to output the dispersed drug mist. The spray valve is equipped with a nebulization flow meter to detect the real-time dispersed particle size of the drug mist and the nebulized airflow rate. This technology adjusts the initial airflow rate based on the rate of change between the real-time respiratory rate and a second standard respiratory rate to ensure that the oxygen supply during nebulization is consistent with the respiratory rate. That is, a faster respiratory rate requires a higher gas flow rate to produce a higher spray volume, allowing the drug to be better inhaled by the user. The controller further adjusts the drug particle size and spray rate to improve drug utilization. However, the process of subtracting the gas flow rate from the measured exhaled gas in this technical solution essentially yields the difference between the human body's exhaled gas flow rate and the gas flow rate input to the mask. For a specific human body, the gas inhaled and the gas exhaled are not equivalent, that is, the gas flow rates are not equivalent. Therefore, it is impossible to correlate the amount of medication inhaled into the respiratory tract by measuring the exhaled gas flow rate alone, and thus it is impossible to obtain an accurate flow adjustment strategy that matches the patient's real-time physiological state.

[0006] This application provides a nebulization system, comprising: an inhalation drug delivery module configured to deliver a drug to a patient via the respiratory tract in a nebulization manner, the module being equipped with a flow detection device to acquire time-related drug flow data during patient use; an auxiliary ventilator configured to be attached to the surface of the patient's respiratory tract area to collect time-related breath sound / lung sound signals during patient use; and an information processing module that generates instructions to adjust the inhalation drug delivery module based on the information collected by the auxiliary ventilator.

[0007] Based on the correlation analysis between the breath sound / lung sound signals collected by the ventilator and the drug flow data, the information processing module generates adjustment instructions regarding nebulization position, breathing mode, and / or nebulized drug ratio.

[0008] Compared with the prior art, the information processing module of the present invention can perform correlation analysis between the respiratory sound / lung sound signals collected by the ventilator and the drug flow data, and generate adjustment instructions for the inhalation drug delivery module regarding nebulization position, breathing mode, and / or nebulized drug ratio. Based on the above distinguishing technical features, the problem to be solved by the present invention may include: how to adjust the implementation parameters of nebulization therapy according to the patient's real-time physiological state, so as to respond in a timely manner to changes in the patient's physiological state and improve the efficiency of nebulization therapy.

[0009] This application uses breath sound / lung sound signals to assess the patient's respiratory status during nebulization and obtains the patient's effect on the nebulization process in real time through the respiratory status, such as the relief of phlegm and dampness. On the one hand, it can confirm whether the nebulization procedure can deliver the drug to the desired area through the patient's nebulization effect; on the other hand, it can also confirm whether the nebulized drug is effective for the patient through the relief or no change in the patient's respiratory / lung symptoms represented by breath sound / lung sound signals.

[0010] This adjustment process relies on breath sound / lung sound signals. The data fed back by these signals represents the response produced in the area where the nebulized drug directly acts. Compared to existing methods that rely on patient cooperation during nebulization to improve nebulization efficiency, this application can generate adjustment commands for the nebulization device in real time based on the feedback generated in the area where the nebulized drug directly acts.

[0011] According to a preferred embodiment, the information processing module is configured to generate a nebulization flow rate adjustment command related to the patient's respiratory rate adjustment based on the frequency of the breath sound / lung sound signal collected by the ventilator.

[0012] Existing technologies have developed solutions for achieving efficient drug inhalation in the upper respiratory tract or lungs by synchronizing the patient's respiratory rate with the respiratory process. For example, CN115569275A discloses a medical micro-mesh nebulization method and system for synchronizing respiratory rate. This system includes an electrocardiogram and respiratory monitoring unit, a nebulization control unit, a nebulization drive unit, and a micro-mesh nebulizer. The electrocardiogram and respiratory monitoring unit monitors the patient's respiratory state in real time, transmitting the real-time data to the nebulization control unit. The nebulization control unit extracts real-time characteristic parameters of the respiratory state based on the monitored data and controls and adjusts the peak driving voltage and vibration frequency of the micro-mesh nebulizer through the boost control and frequency modulation control circuits of the nebulization drive unit. This ensures that the peak driving voltage and vibration frequency change with the real-time characteristic parameters of the respiratory state, achieving real-time synchronization between the nebulization system's mist output and rate of mist emission and the respiratory rhythm. The nebulization system of this technology can synchronize the change cycle of the mist output and mist output rate with the patient's breathing rhythm in real time. This solves the technical problem that the existing nebulization system cannot adapt to the patient's breathing, resulting in the inefficient inhalation of the drug into the upper respiratory tract or lungs and the inability to monitor the patient's safe nebulization status.

[0013] This application includes an auxiliary ventilator that prompts the patient to exhale or inhale. The information processing module controls the auxiliary ventilator to generate corresponding breathing prompts at a preset time (e.g., 0.5s) ahead of the drug delivery rhythm of the inhalation module, in order to correct for the time error caused by the coordination of the patient's inhalation action and the nebulizer's drug delivery action due to nebulization delivery.

[0014] In existing technologies, the matching of respiratory rate and drug administration rate mostly relies on the patient's self-regulation of breathing rhythm, but ignores the transmission delay caused by the drug administration route, which makes the coordination between the two affected by objective factors such as tubing resistance.

[0015] This application addresses the problem of transmission lag in the drug delivery pathway, ensuring that the coordination between the device's drug delivery frequency and respiratory rate is only affected by the patient's compliance, thus eliminating interference from objective factors such as tubing resistance.

[0016] According to a preferred embodiment, the information processing module is configured as follows:

[0017] Based on the intensity of breath sound / lung sound signals collected by the ventilator, nebulized particle adjustment instructions are generated in relation to changes in the patient's sputum-dampness symptoms.

[0018] According to a preferred embodiment, the information processing module is configured to generate adjustment instructions to alleviate abnormal symptoms caused by nebulization in patients based on abnormal changes in breath sound / lung sound signals collected by the ventilator.

[0019] Compared with the prior art, the information processing module of the present invention can generate nebulized particle adjustment instructions related to changes in the patient's phlegm-dampness symptoms based on the intensity of the breath sound / lung sound signals collected by the ventilator. Based on the above distinguishing technical features, the problem to be solved by the present invention may include: how to adjust the site of drug action under phlegm-dampness symptoms to improve the effectiveness of the corresponding drug in treating specific diseases.

[0020] The diameter of nebulized particles is a crucial factor influencing drug deposition in different parts of the respiratory tract. Existing technologies, such as the personalized, precise positioning, and intelligent control nebulization system disclosed in CN117224786A, adjust the size of nebulized particles by inverting and calculating the inhalation parameters deposited at that location. Numerical simulation combined with nebulization experiments is used to study the deposition patterns of novel compound nebulized drug particles in the human airway, establishing a database of different drug inhalation parameters to evaluate the matching degree between nebulized particle diameter and patients.

[0021] In practice, due to significant individual differences, the calculation model can be affected by these differences (e.g., patients with complications, patients with congenital airway stenosis), leading to increased errors in nebulized particle adjustment and causing the adjusted parameters to be unsuitable for the patient. Unlike the aforementioned prior art, this application uses real-time detected dynamic changes in lung / breath sounds to determine whether the current nebulized particle size matches the intended deposition site. Specifically, by comparing lung / breath sounds generated at various locations before and during nebulization for the same patient, the information processing module can exclude lung / breath sounds generated during normal breathing in the audio during nebulization and obtain the audio generated by the nebulized airflow within the lung / breath sounds. The location where this audio is generated indicates the endpoint of the nebulized airflow, thus confirming the effectiveness of the current nebulization.

[0022] According to a preferred embodiment, the information processing module is configured to connect to a remote medical care terminal, and when the remote medical care terminal receives one or more respiratory sound / lung sound signals collected by the patient from the ventilator, control the inhalation drug delivery module to adjust the drug ratio of the patient's nebulization based on the drug ratio instruction sent by the remote medical care terminal.

[0023] The drug formulation adjustments involved in this application are applicable to patients with chronic diseases who require long-term or high-frequency home nebulization, such as COPD patients. These patients have limited mobility and are easily affected by environmental factors, leading to lung disease symptoms that impact their quality of life, such as coughing and wheezing with excessive phlegm during smoggy weather. However, due to their limited mobility, going to the hospital for examination when disease symptoms appear reduces their motivation to use nebulization or to change medications to minimize the impact of disease symptoms on their quality of life.

[0024] The system involved in this application can remotely communicate with medical staff responsible for the diagnosis and treatment of patients with chronic diseases, provided that the hospital's HIS (Hospital Information System) is authorized, and adjust the nebulized drug ratio under the guidance of medical staff within the permitted permissions (such as sending the patient's affected symptoms to the medical staff or sending the patient's medical history to the medical staff with mutual consent).

[0025] This application takes into account both the patient's adaptability during drug use and the drug ratio for each nebulization in a course of treatment. This allows the entire nebulization course to change according to changes in the patient's body (such as the development of respiratory diseases or changes caused by environmental influences). These changes occur not only during nebulization but also before and after each nebulization. This makes the system involved in this application fit the patient's condition and improve the nebulization effect.

[0026] According to a preferred embodiment, the ventilator includes a breath sound collection unit capable of collecting breath sounds from the patient's upper respiratory tract and lungs.

[0027] According to a preferred embodiment, the ventilator further includes an inflatable garment for assisting the patient in adjusting their breathing rate, wherein the inflatable garment is configured to be worn on the patient's body, the garment including a front, a back, and an inflatable bladder at least incorporated in or on the front, the front and / or back including recesses configured to press against the patient's body surface for placing a breath sound collecting unit.

[0028] According to a preferred embodiment, when the inflatable bladder is inflated so that the worn clothing presses against the patient's body surface, the breath sound collection unit placed in the recess is able to collect at least the patient's bronchial breath sounds, vesicular breath sounds, and / or bronchovesicular breath sounds.

[0029] According to a preferred embodiment, the inhalation drug delivery module includes a drive unit, a drug container regulated by the drive unit, and an atomizing unit that turns the drug into an aerosol. The drive unit includes a connector assembly disposed between the drug container and the atomizing unit. The connector assembly includes a needle and a suction pump. Regulated by an information processing module, the needle can pierce a drug bottle engaged in the drug container and, under the action of the suction pump, cause the drug in the drug bottle to flow into the atomizing unit.

[0030] According to a preferred embodiment, the medicine container includes a first medicine container and a second medicine container, and the first medicine container and the second medicine container can be individually adjusted by the drive unit to administer the medicine.

[0031] This application also provides a nebulization aid device that can be used in conjunction with an inhalation drug delivery module for administering drugs to a patient via nebulization. The device includes an auxiliary ventilator and an information processing module. The auxiliary ventilator is configured to adhere to the surface of a patient's airway region and collect time-related respiratory / lung sound signals during patient use. The auxiliary ventilator includes an inflatable garment worn on the patient's body to assist in regulating the patient's respiratory rate and a respiratory sound collection unit disposed on the inflatable garment for collecting the patient's lung / breath sounds. The information processing module analyzes and processes the information collected by the auxiliary ventilator to generate adjustment commands. The information processing module obtains the patient's respiratory rate based on the time-series data of respiratory sounds collected by the respiratory sound collection unit and determines the activation time of the inflatable garment based on the matching between the patient's respiratory rate and the drug delivery frequency of the inhalation drug delivery module.

[0032] According to a preferred embodiment, when the information processing module determines that the patient's respiratory rate does not match the drug delivery frequency of the inhalation drug delivery module, the inflatable garment is activated to assist the patient in adjusting their respiratory rate.

[0033] According to a preferred embodiment, when the inflatable garment is in operation, the fluid supply unit can inflate and deflate the inflatable bladder of the garment at the same frequency as the drug delivery frequency of the inhalation drug delivery module. Attached Figure Description

[0034] Figure 1 is a diagram showing the usage status of the atomization system provided by the present invention;

[0035] Figure 2 is a hardware connection diagram of the atomization system provided by the present invention;

[0036] Figure 3 is a schematic diagram of information interaction among the functional modules of the atomization system provided by the present invention.

[0037] Figure 4 is a flowchart of the detection process provided by the present invention.

[0038] List of reference numerals: 100: Assisted respirator; 110: Breath sound collection unit; 120: Inflatable garment; 121: Clothing; 1211: Front of clothing; 1212: Back of clothing; 122: Inflatable airbag; 123: Fluid supply unit; 200: Information processing module; 300: Inhalation drug delivery module; 310: Drive unit; 320: Nebulizer unit; 330: Drug container; 331: First drug container; 332: Second drug container; 340: Scanning lens. Detailed Implementation

[0039] The following is a detailed explanation with reference to the accompanying drawings.

[0040] Example 1

[0041] This embodiment provides a nebulization system, and more particularly a system for evaluating the real-time therapeutic effect of nebulization speed, nebulized particles, and nebulized drug ratio in children based on feedback from children's breath sounds / lung sounds during nebulization, and the matching degree between these parameters and the patient.

[0042] This embodiment provides a nebulization system, particularly a system for evaluating the real-time therapeutic effect of nebulization speed, nebulized particles, and nebulized drug ratio in adult patients with respiratory diseases, based on feedback from the adult patient's breath / lung sound signals, to assess the compatibility of these parameters with the patient. Specifically, the system described in this application is suitable for elderly individuals with a long history of home nebulization.

[0043] Figure 2 shows the functional structure diagram of this system. In this application, the ventilator 100, the information processing module 200, and the inhalation drug delivery module 300 can establish a communication connection via a wireless network (e.g., Bluetooth, WIFI, NFC, infrared technology, etc.) to exchange data, signals, and / or control signals.

[0044] This application relates to an assistive ventilator 100. The assistive ventilator 100 includes a respiratory sound collection unit 110 for collecting lung sounds / breath sounds from a patient, and an inflatable garment 120 for assisting the patient in adjusting their respiratory rate. Preferably, the assistive ventilator 100 further includes a power supply unit for providing power to the respiratory sound collection unit 110 and the inflatable garment 120, a communication module for receiving instructions sent by an information processing module 200, and a microprocessor for converting the data collected by the respiratory sound collection unit 110 to increase the speed at which the communication module presents data to the information processing module 200. The communication module can transmit the collected information to the information processing module 200 via a cable port, a wireless transmitter, or a combination of the above signal transmission methods. Preferably, the information processing module 200 is integrated into an inhalation drug delivery module 300, or integrated into a patient's handheld terminal, so that the patient can adjust the inhalation drug delivery module 300 via a handheld terminal such as a mobile phone.

[0045] The breath sound collection unit 110 is equipped with an auscultation acquisition circuit and a differential amplifier circuit. The auscultation acquisition circuit and the differential amplifier circuit can be configured as disclosed in the acquisition circuit of CN217904638U.

[0046] As shown in Figure 1, the inflatable garment 120 is configured to be worn on the patient's body as clothing 121. Clothing 121 includes a front garment 1211, a back garment 1212, and an inflatable air bladder 122 incorporated in or on the front garment 1211. The front garment 1211 and / or the back garment 1212 include recesses configured to press against the patient's body surface for placing a breath sound collecting unit 110.

[0047] The garment 121 can be configured as an inflatable vest or other clothing that can be worn over the chest to create a feeling of compression on the patient's chest. The inflatable airbag 122 located on the garment 121 can generate corresponding inflation or deflation programs in response to the patient's inhalation or exhalation. When the patient needs to maintain an inhalation, the inflatable airbag 122 is in a deflated state, allowing the patient to expand their chest and / or abdomen. When the patient needs to maintain an exhalation, the inflatable airbag 122 is inflated, allowing the patient to contract their chest and / or abdomen.

[0048] Specifically, the inflatable airbag 122 installed on the clothing 121 needs to compress the patient's chest cavity when inflated so that the patient feels a sense of compression in the chest cavity, or the patient feels a sense of relaxation in the chest cavity through the deflation of the inflatable airbag 122, thereby ensuring that the patient can regulate the breathing rate through perception.

[0049] When the inflatable airbag 122 is inflated, causing the worn garment 121 to press against the patient's body surface, the breath sound collecting unit 110 placed in the recess is able to collect at least the patient's bronchial breath sounds, vesicular breath sounds, and / or bronchovesicular breath sounds. Preferably, the garment 121 has recesses corresponding to the upper, middle, and lower parts of the patient's midclavicular line; the upper and lower parts of the anterior axillary line; and the upper and lower parts of the midaxillary line, or recesses corresponding to the auscultatory array disclosed in CN217904638U are provided on the garment 121. Preferably, one or more breath sound collecting units 110 are placed in one recess. The breath sound collecting unit 110 is flush with the surface of the garment 121. The recess is provided with a connector for detachably connecting the breath sound collecting unit 110 to the garment 121. The connector can be a button, hook, magnetic button, frame, Velcro, etc.

[0050] This application also relates to an inhalation drug delivery module 300. As shown in Figures 1 and 2, the inhalation drug delivery module 300 includes a drive unit 310, a drug liquid container 330 regulated by the drive unit 310, and an atomizing unit 320 that turns the drug liquid into an aerosol.

[0051] The medication container 330 is connected to the nebulizer unit 320 via the drive unit 310, and the amount and type of medication flowing into the nebulizer unit 320 are adjusted by the drive unit 310. Preferably, the medication container 330 includes a first medication container 331 and a second medication container 332, which can be individually adjusted by the drive unit 310 to administer medication. Preferably, when mixed administration is required, the drive unit 310 can simultaneously control the flow of medication from the first medication container 331 and the second medication container 332 into the nebulizer unit 320. It should be noted that the number of medication containers 330 is not limited. The first medication container 331 and the second medication container 332 are merely preferred embodiments. The number of medication containers 330 in this application can be set to two or more, and each can be independently controlled by the drive unit 310.

[0052] The atomizing unit 320 is a device that alters the physical form of a liquid medicine using ultrasonic or high-speed jet methods, enabling the incoming liquid medicine to be ejected in the form of an aerosol. Preferably, the atomizing unit 320 is an ultrasonic device. The power of the atomizing unit 320 can be controlled and adjusted.

[0053] When the drive unit 310 receives an instruction transmitted by the communication module and sent by the information processing module 200, it generates a corresponding liquid adjustment action.

[0054] When the liquid medicine container 330 is a manual dispensing container as shown in the prior art, the drive unit 310 can be configured as a pump, which can select the amount of liquid medicine drawn by adjusting its power. When there are two or more liquid medicine containers 330, the pump of the drive unit 310 can be configured for each liquid medicine container 330, or a controlled valve can be configured between each liquid medicine container 330 and the atomizing unit 320. The liquid medicine transfer speed / transfer volume of different liquid medicine containers 330 can be adjusted by adjusting the power of the pump and the opening and closing of the valve.

[0055] Furthermore, considering that nebulization therapy is a course of treatment, and patients need to clean the medication container 330 each time they use nebulization, this application provides a disposable medication bottle and an inhalation delivery module 300 used in conjunction with the medication bottle.

[0056] As shown in Figure 1, the drive unit 310 includes a connector assembly disposed between the medicine container 330 and the atomizing unit 320. The medicine container 330 is shaped to hold a medicine bottle. The connector assembly is fitted onto the liquid outlet of the medicine bottle, and an opening is made at the liquid outlet by means of twisting, pricking, etc. Preferably, the connector assembly includes a needle and a suction pump. Under the regulation of the information processing module 200, the needle can pierce the medicine bottle held in the medicine container 330, and the liquid in the medicine bottle flows into the atomizing unit 320 under the action of the suction pump. The medicine obtained by this method can avoid contamination caused by contact with air.

[0057] According to a preferred embodiment, a scanning lens 340 is provided at the position corresponding to the bottle body in the medicine container 330. When the medicine bottle is engaged in the medicine container 330, the scanning lens 340 confirms whether the medicine has been correctly selected by acquiring information about the bottle body or other information present on the bottle body (such as a QR code).

[0058] This application also relates to an information processing module 200. The information processing module 200 can be a smartphone, smartwatch, or other wearable device, tablet, computer, cloud server, or other intelligent device with a CPU and communication module, and can be worn by the patient's caregiver. When the caregiver is not present, a conscious adult patient can wear the nebulizer independently and confirm whether the medication has been correctly added based on the scanning lens 340. When the operating procedure is correct, the caregiver can remotely control the system to start. The CPU receives detection signals from the ventilator 100 via the communication module and converts the detection signals into processable data for further generating signals to control the inhalation drug delivery module 300.

[0059] Alternatively, the information processing module 200 can be integrated into the ventilator 100 or the inhalation drug delivery module 300. The patient can adjust the nebulization process based on lung sound / breath sound feedback by operating the ventilator 100 or the inhalation drug delivery module 300.

[0060] In this embodiment, the ventilator 100 is an example of an inflatable vest, as shown in Figure 1. After the patient wears the ventilator 100, the ventilator 100 is wrapped around the patient's chest cavity through the connecting components such as buttons and zippers on the front.

[0061] After the system is awakened by external input information, the breath sound collection unit 110 begins to collect the patient's initial lung sounds / breath sounds before nebulization.

[0062] After confirmation of external input information and the patient correctly wearing the inhalation drug delivery module 300, the inhalation drug delivery module 300 starts working based on a preset program (such as interferon and saline being mixed and introduced into the drug container 330, and starting to work with 4μm atomized particles and a spray speed of 0.8mL / min).

[0063] The breath sound collection unit 110 processes the collected data through the microprocessor of the ventilator 100 and presents it to the communication module of the ventilator 100, which then sends it to the communication module of the information processing module 200. The CPU of the information processing module 200 processes relevant information, namely, generating information such as the patient's respiratory rate and sputum moisture status based on the tonal and other waveform characteristics of breath sounds / lung sounds. The CPU generates at least three judgments by comparing the breath sounds / lung sounds sent at different time periods, including whether there is a situation where nebulization needs to be stopped and a warning broadcast command should be sent through the set voice broadcast unit; the synergy between the patient's respiratory rate and the drug delivery frequency of the inhalation drug delivery module 300; and whether the breath sounds / lung sounds of the patient's deteriorating tendency have been relieved (e.g., whether the duration of wheezing has decreased).

[0064] Simultaneously, based on the drug delivery frequency of the inhalation drug delivery module 300, the CPU can control the inflatable garment 120 to expand (inflate) or contract (deflat) in tandem with the communication module of the ventilator 100 at preset time values. The ventilator 100 can regulate the inflation and deflation of the inflatable garment 120 by controlling the fluid supply unit 123. For example, when the inhalation drug delivery module 300 sprays medication into the patient's mouth and nose, based on the drug's transport time in the tubing, the CPU controls the inflatable garment 120 to relax with a 0.5-second delay. This corrects for the time error caused by the nebulizer's delivery action during the coordination of the patient's inhalation and the nebulizer's drug delivery action, ensuring that the patient's inhalation and drug delivery are synchronized. Furthermore, the relaxation time of the inflatable garment 120 is the drug delivery time of the inhalation drug delivery module 300. For example, if the inhalation drug delivery module 300 sprays medication for 3 seconds, the inflatable garment 120 relaxes for 3 seconds and continues to inflate for 3 seconds during the 3 seconds after the inhalation drug delivery module 300 stops delivering medication, the patient can exhale continuously during the 3-second inflation period of the inflatable garment 120.

[0065] According to a preferred embodiment, this application also relates to a nebulization aid device, which includes the above-mentioned ventilator 100 and the above-mentioned information processing module 200, wherein the nebulization aid device can be used in conjunction with the above-mentioned inhalation drug delivery module 300 for delivering drugs to patients via the respiratory tract in a nebulization manner.

[0066] Example 2

[0067] This embodiment provides a nebulized drug delivery method for adjusting respiratory rate, as shown in Figure 4. This nebulized drug delivery method can be used with the nebulization auxiliary equipment and / or nebulization system described in previous embodiments. In this embodiment, except for the control method of the information processing module 200 on the inhalation drug delivery module 300, the other hardware is the same as in previous embodiments.

[0068] Based on the correlation analysis between the breath sound / lung sound signals collected by the ventilator 100 and the drug flow data, the information processing module 200 generates adjustment instructions for the breathing mode, as shown in Figure 3.

[0069] Based on the frequency of the breath sound / lung sound signals collected by the ventilator 100, a nebulization flow rate adjustment command related to the patient's respiratory rate adjustment is generated, as shown in Figure 3.

[0070] Specifically, the information processing module 200 obtains the patient's respiratory rate based on the time-series data of respiratory sounds collected by the respiratory sound collection unit 110, and matches it with the drug delivery frequency of the inhalation drug delivery module 300.

[0071] When the patient's respiratory rate does not match the medication delivery rate, the inflatable garment 120 is activated.

[0072] The fluid supply unit 123 inflates and deflates the air bladder 122 of the garment 121 at the same frequency as the drug delivery frequency. When the patient wearing the garment 121 feels the compression and relaxation of the garment 121, they can synchronously adjust their breathing rate, so that the patient's breathing can be coordinated with the drug delivery frequency, thereby achieving the optimal drug delivery effect.

[0073] Meanwhile, considering that the inhalation drug delivery module 300 delivers medication to the patient via tubing, synchronizing the drug delivery frequency with the respiratory frequency in time will cause an error in the drug flow time through the tubing and the airflow time during the patient's breathing, resulting in a mismatch between the patient's inhalation and the drug delivery actions of the inhalation drug delivery module 300. The information processing module 200 can control the ventilator 100 to generate corresponding breathing prompts at a preset time earlier than the drug delivery rhythm of the inhalation drug delivery module 300, in order to correct the time error caused by the coordination between the patient's inhalation and the nebulizer's drug delivery actions due to nebulization delivery. Preferably, the preset time can be automatically adjusted during device use, that is, the preset time will change with the change in the flow rate of the nebulized drug. Generally speaking, the faster the flow rate, the shorter the preset time in the same tubing.

[0074] Example 3

[0075] This embodiment provides a nebulized drug delivery method for adjusting the nebulized drug ratio, as shown in Figure 4. This nebulized drug delivery method can be used with the nebulization auxiliary equipment and / or nebulization system described in previous embodiments. In this embodiment, except for the control method of the information processing module 200 on the inhalation drug delivery module 300, the other hardware is the same as in previous embodiments.

[0076] Based on the correlation analysis between the breath sound / lung sound signals collected by the ventilator 100 and the drug flow data, the information processing module 200 generates an adjustment instruction for the nebulized drug ratio, as shown in Figure 3.

[0077] For patients with chronic obstructive pulmonary disease or other conditions requiring long-term nebulization, the information processing module 200 involved in this application can connect to the hospital information system to provide medical staff with the patient's lung sounds / breath sounds or to provide medical staff with nebulization drug adjustment plans based on the lung sounds / breath sounds generated during different nebulization sessions.

[0078] The information processing module 200 can confirm the nebulization effect on the patient by analyzing the time-series data of the collected lung sounds / breath sounds.

[0079] The information processing module 200 uses two mechanisms, a and b, to determine the drug compatibility during nebulizer treatment:

[0080] a. After obtaining the breath sounds / lung sounds collected by the breath sound collection unit 110, the information processing module 200 confirms whether the patient has symptoms other than those that can be treated with nebulized drugs based on the preset standard parameters of the breath sounds / lung sounds.

[0081] b. After obtaining the breath sounds / lung sounds collected by the breath sound collection unit 110, the CPU of the information processing module 200 sends a query request to the database of the information processing module 200 to obtain the breath sound / lung sound data of the patient in the most recent nebulization process in time with the current nebulization number.

[0082] By comparing historical breath / lung sound data with the breath / lung sound data produced during the current nebulization session, and combining this with the therapeutic capacity of the nebulized medication, it can be determined whether the patient's symptoms related to the therapeutic capacity of the nebulized medication have been relieved.

[0083] Preferably, considering the time-limited effect of nebulization on patients, the CPU can obtain respiratory sound / lung sound data of three patients during nebulization.

[0084] For example, after the patient completes the fourth nebulization, the information processing module 200 uses the breath sound / lung sound data collected by the breath sound collection unit 110 to determine program a and program b respectively.

[0085] Procedure a is for the judgment of new symptoms. When the duration or frequency response value of the disease-related breath sounds / lung sounds collected by the breath sound collection unit 110 is higher than the preset duration or frequency response value of the disease-related breath sounds / lung sounds, and the symptoms corresponding to this feature (e.g., bronchospasm, airway stenosis) are not within the treatment range of nebulized drugs (e.g., ambroxol hydrochloride injection with mucus discharge promotion effect), the information processing module 200 generates a plan to supplement the nebulized drugs related to the above symptoms (e.g., terbutaline sulfate nebulized solution that can dilate the bronchi and relieve bronchospasm) and submits it to the HIS system through the communication module. Medical staff confirm the feasibility of the plan through the HIS system and provide feedback to the information processing module 200. At the same time, medical staff can also notify the patient or their guardian (the contact person stored in the HIS system) to go to the designated hospital to pick up the medication through the HIS system. After the information processing module 200 obtains authorization from the medical staff, it can send relevant drug adjustment instructions to the inhalation drug delivery module 300. That is, during the next nebulization, after the adjusted nebulization drugs (ambroxol hydrochloride injection and terbutaline sulfate nebulization solution) are successfully scanned by the scanning lens 340 of the inhalation drug delivery module 300, the inhalation drug delivery module 300 provides nebulization treatment to the patient based on the drug ratio sent by the information processing module 200.

[0086] Program b is for assessing the progression of existing symptoms. After obtaining breath sounds / lung sounds collected by the breath sound collection unit 110, the CPU of the information processing module 200 sends a query request to the database of the information processing module 200 to obtain breath sound / lung sound data from at least the most recent nebulization session for the patient. By comparing historical breath sound / lung sound data with the breath sound / lung sound data generated during the current nebulization session, and considering the therapeutic ability of the nebulized medication, it is determined whether the patient's symptoms related to the therapeutic ability of the nebulized medication have been relieved. When the frequency response value of the moist rales in the current nebulization session is higher than that in the previous nebulization session, based on the association between moist rales and sputum accumulation in the lungs or respiratory tract, the information processing module 200 generates a plan to replace the medication with one that promotes mucus discharge or to increase the dosage of ambroxol hydrochloride injection, which also promotes mucus discharge. This plan is then submitted to the HIS system via the communication module. Medical staff confirm the feasibility of the plan through the HIS system and provide feedback to the information processing module 200. When the implementation plan is confirmed to involve changing medication, healthcare professionals can also notify the patient or their guardian (a contact person registered in the HIS system) to pick up the medication at a designated hospital via the HIS system. After obtaining authorization from the healthcare professional, the information processing module 200 can send relevant medication adjustment instructions to the inhalation drug delivery module 300. That is, during the next nebulization session, after the adjusted nebulized medication (e.g., ambroxol hydrochloride injection dosage changed from 1 mL to 2 mL) is successfully scanned by the scanning lens 340 of the inhalation drug delivery module 300, the inhalation drug delivery module 300 provides nebulization treatment to the patient based on the medication ratio sent by the information processing module 200.

[0087] Example 4

[0088] This embodiment provides a nebulized drug delivery method for adjusting the nebulized drug ratio, as shown in Figure 4. This nebulized drug delivery method can be used with the nebulization auxiliary equipment and / or nebulization system described in previous embodiments. In this embodiment, except for the control method of the information processing module 200 on the inhalation drug delivery module 300, the other hardware is the same as in previous embodiments.

[0089] Based on the correlation analysis between the breath sound / lung sound signals collected by the ventilator 100 and the drug flow data, the information processing module 200 generates adjustment instructions for the nebulization position, as shown in Figure 3.

[0090] Existing technology indicates that the size of atomized particles is the main factor affecting the adhesion site of nebulized drugs: atomized particles with a diameter greater than 10 μm can only accumulate in the oral cavity; atomized particles with a diameter of 5–10 μm can flow into the patient's throat; atomized particles with a diameter of 3–5 μm can flow into the patient's lung parenchyma and bronchi; atomized particles with a diameter of 1–3 μm can flow into the depths of the patient's lungs; and atomized particles with a diameter of less than 1 μm will be expelled with respiration.

[0091] The breath sound collection unit 110 involved in this application can acquire breath sounds from the patient's airway and lung sounds from the lungs based on auscultation acquisition circuits respectively installed in the patient's upper respiratory tract and lungs. More specifically, the auscultation acquisition circuits can also acquire breath sounds and lung sounds from the patient at different locations on the patient's anterior chest and posterior back. For example, auscultation acquisition circuits can be installed in the supraclavicular fossa, suprasternal fossa, larynx, and / or C6-C7 vertebrae to acquire breath sounds from different segments of the airway.

[0092] Even when using nebulized particles with a diameter of 3–5 μm, the depth to which the drug reaches can vary depending on individual differences (such as the condition of the respiratory mucosa and the diameter of the respiratory tract). This application utilizes collected lung sounds / breath sounds to provide timely information on the depth of the nebulized drug in the patient's respiratory tract and lungs during nebulization, enabling the inhalation drug delivery module 300 to be more precisely adjusted within a preset nebulized particle size range. The adjustment method includes changing the operating power of the nebulization unit 320.

[0093] When a patient undergoes nebulization, the airflow noise from the nebulizer causes the breath sounds and lung sounds collected by the breath sound collection unit 110 to include additional frequency characteristics. Based on these frequency characteristics collected at different locations, the information processing module 200 can determine the depth of the nebulized medication. Based on the patient's pre-set medication depth (lung parenchyma), and when sound matching the nebulizer airflow frequency characteristics is detected only in the lower bronchus, the information processing module 200 can control the nebulizer unit 320 to adjust its operating power, reducing the size of the nebulized particles by one unit. Preferably, one unit is a preset value, which can be equivalent to a change of 0.5 μm in the diameter of the nebulized particles.

[0094] Example 5

[0095] During repeated nebulization sessions, a patient's lung sounds may change (e.g., increase or decrease in intensity). This change can be reflected in the duration and frequency of wheezing. When there are partial changes in the trachea, which includes the bronchi, bronchioles, or small bronchioles (e.g., obstruction or worsening of phlegm symptoms), the resistance to airflow through these areas increases, leading to an increase in the duration and pitch of wheezing in the lung sounds.

[0096] According to a preferred embodiment, the breath sound collection units 110 are respectively disposed at the locations corresponding to the patient's main trachea, left bronchus, left lung, right lung, and right bronchus. When abnormal changes occur in the lung sound information collected by the breath sound collection units 110 at some locations, the information processing module 200 can control the breath sound collection units 110 at other locations to stop collecting information, thereby increasing the accuracy of information collection.

[0097] For example, when the pitch of the wheezing sound collected by the breath sound collection unit 110 set in the left bronchus increases during the patient's nebulization process, the information processing module 200 adjusts the nebulized particle size or nebulization flow rate based on this data, which indicates that the sputum and dampness in the left bronchus has worsened.

[0098] When the size of the atomized particles is within the range that can be delivered to the bronchi, the information processing module 200 increases the atomization flow rate according to a preset threshold.

[0099] When the size of the atomized particles does not match the particle size to be delivered to the bronchi, the information processing module 200 adjusts the power of the atomizing unit 320 so that the size of the atomized particles matches the particle size to be delivered to the bronchi.

[0100] The system and equipment involved in this application open specific acquisition channels for different symptoms in order to obtain more accurate adjustment effects and prevent interference from signals from other parts of the body.

[0101] Example 6

[0102] This embodiment is a further improvement on the foregoing embodiment, and repeated content will not be described again.

[0103] This embodiment provides a method for implementing a nebulization system based on dynamic coupling of respiration and drug delivery, which is particularly suitable for drug delivery control in patients with chronic respiratory diseases. The hardware architecture of the nebulization system is shown in Figures 1 and 2, and includes three parts working together: a ventilator 100, an information processing module 200, and an inhalation drug delivery module 300. The ventilator 100 includes a six-channel respiratory sound collection unit 110 (as part of a respiratory sound acquisition array) deployed on the patient's chest and abdomen, and an inflatable pressure garment 120 (including a garment 121, an inflatable air bag 122, and a fluid supply unit 123). The inhalation drug delivery module 300 integrates a nebulization unit 320 with a dual-drug cartridge structure (including a first drug cartridge 331 and a second drug cartridge 332). The information processing module 200 connects to the respiratory sound sensor via a built-in Bluetooth communication unit and establishes a data interaction channel with a cloud-based medical information system via a Wi-Fi module.

[0104] The system's operational characteristic lies in establishing a dynamic coupling mechanism between respiratory phase monitoring and drug administration timing control. The implementation method includes the following steps:

[0105] S1, Respiratory-Drug Delivery Synchronization Initialization

[0106] [Amended according to Rule 26, March 2024] In the patient's resting state, a 30-second breath sound signal is collected by the breath sound collection unit 110, based on the baseline value T of the respiratory cycle collected in the patient's resting state. b (0) Calculate the initial respiratory rate f d (0):

[0107] Wherein, parameter T b (0) The baseline value of the respiratory cycle in the patient's resting state is used to convert the initial respiratory rate f to 60 times its reciprocal. d (0), this parameter serves as the core input for system initialization. For example, if a patient's baseline respiratory cycle at rest is 3.2 seconds, then their initial respiratory rate is 18.75 breaths / min.

[0108] Then based on the initial respiratory rate f d (0) and the synchronization coefficient α are used to calculate the initial drug delivery frequency f. d (0): f d (0)=α·f b (0),

[0109] The synchronization coefficient α, ranging from 0.9 to 1.1, defines the dynamic matching range between the drug delivery frequency and the respiratory rate. Its engineering significance lies in balancing treatment safety and drug delivery efficiency. For example, when the synchronization coefficient α is 1.05, the initial drug delivery frequency for the aforementioned patients is 19.69 times / min.

[0110] Simultaneously, the periodic inflation frequency and real-time drug delivery frequency f of the inflatable suit 120 are set. d (t) are equal, and the tubing delay compensation Δt is calculated based on the nebulization tubing length and airflow velocity to ensure that the nebulized particles reach the airway in the early stage of the patient's inspiratory phase. For example, for a nebulization tubing length of 1.2m and an airflow velocity of 0.8m / s, the tubing delay compensation Δt is the quotient of the two, i.e., 1.5s.

[0111] S2, Dynamically adjust atomization flow rate and particle size.

[0112] During the dynamic adjustment phase, a multi-parameter closed-loop control strategy can be adopted, and the information processing module 200 analyzes the breath sound intensity signal S in the right middle lobe of the lung in real time. lung (t), and the current atomization output flow rate can be calculated through the flow control equation: Q(t)=β·S lung (t)·f d (t),

[0113] Where β is the system's preset sensitivity coefficient, which can be 0.1 mL / (s·mV); f d (t) represents the real-time drug delivery frequency. When t = 0, it represents the initial drug delivery frequency. For example, when the initial intensity of breath sounds in the right middle lobe of the above patient was monitored to be 120 mV, the initial nebulizer output flow rate was calculated to be 236.3 mL / min.

[0114] To address the deposition characteristics of particles with different sizes, the system established a constraint equation between the real-time drug delivery frequency and the target particle size:

[0115] Where k1 is the particle dynamics coefficient, which physically reflects the delivery capability of particles of a specific size per unit time, and can be taken as 200 μm. 2 / times; d p (t) represents the target particle size.

[0116] Preferably, when the selected target particle size is 5 μm, a frequency allocation command is generated. Dual-channel coordinated control is performed with a weight of γ1 = 0.6 for the bronchial region and γ1 = 0.4 for the alveolar region to meet local drug concentration requirements and overall respiratory rhythm synchronization. For example, when the current target particle size is 5 μm, the real-time drug delivery frequency is 8 times / min, which conflicts with the initial drug delivery frequency of 19.69 times / min, triggering weight allocation. The specific regional frequency allocation scheme is as follows:

[0117] Among them, f d,bronchi For the frequency of drug delivery to the bronchial region; f d,alveoli The frequency of drug delivery to the alveolar region.

[0118] S3, Abnormal Status Intervention

[0119] [Revised from Rule 26 to 24.03.2026] A wheezing sound recognition algorithm was designed for the abnormal intervention phase. When the amplitude of bronchial breath sounds exceeds the threshold, a frequency adjustment equation is activated to generate a correction instruction:

[0120] Among them, A wheeze Abnormal bronchial breath sound amplitude; A normal For normal bronchial breath sound amplitude, the differential term df d The negative sign of / dt indicates the system's inhibitory response mechanism to abnormal states.

[0121] Furthermore, the inflatable garment 120 can activate a high-frequency vibration mode in response to a correction command to assist in expectoration, such as by achieving forced exhalation at twice the drug delivery frequency.

[0122] S4, Remote Medical Collaboration

[0123] In the remote medical collaboration phase, controllable updates of treatment parameters are achieved. The information processing module 200 uploads the historical drug supply frequency sequence to the hospital information system (HIS), performs frequency iteration calculations after receiving the medical order parameters, and implements output limiting protection in combination with the maximum safe frequency threshold.

[0124] Preferably, the key operating parameters of the system include the synchronization coefficient α (0.9–1.1), the pipeline delay compensation Δt (0.3–1.5), and the target particle size d. p (1~10μm) and bronchial drug delivery weight γ1 (0.4~0.7). This embodiment fully realizes the technical effects of "precise timing control" and "multimodal adjustment" by constructing a three-layer control architecture of respiratory signal feature extraction, dynamic matching of nebulization parameters and remote command fusion.

Claims

1. A nebulization aid device, which can be used in conjunction with an inhalation delivery module (300) for delivering a drug to a patient via nebulization, characterized in that, It includes: An auxiliary ventilator (100) is configured to be attached to the surface of a patient’s airway region to collect time-related breath sounds / lung sounds during patient use. The auxiliary ventilator (100) includes an inflatable garment (120) worn on the patient’s body to assist the patient in regulating their respiratory rate and a breath sound collection unit (110) disposed on the inflatable garment (120) to collect the patient’s lung sounds / breath sounds. The information processing module (200) is used to analyze and process the information collected by the ventilator (100) to generate adjustment commands, wherein... The information processing module (200) obtains the patient's respiratory rate based on the time-series data of respiratory sounds collected by the respiratory sound collection unit (110), and determines the start time of the inflatable garment (120) according to the matching of the patient's respiratory rate with the drug delivery frequency of the inhalation drug delivery module (300).

2. The atomization auxiliary device according to claim 1, characterized in that, When the information processing module (200) determines that the patient's respiratory rate does not match the drug delivery frequency of the inhalation drug delivery module (300), the inflatable garment (120) is activated to assist the patient in adjusting their respiratory rate.

3. The atomization auxiliary device according to claim 1 or 2, characterized in that, The inflatable garment (120) is configured to be worn on the body of a patient as an outfit (121), the outfit (121) including a front (1211), a back (1212) and an inflatable airbag (122) incorporated in or on the front (1211), the inflatable airbag (122) being in communication with a fluid supply unit (123).

4. The atomizing auxiliary device according to any one of claims 1 to 3, characterized in that, When the inflatable garment (120) is activated, the fluid supply unit (123) can inflate and deflate the inflatable airbag (122) of the garment (121) at the same frequency as the drug delivery frequency of the inhalation drug delivery module (300).

5. The atomizing auxiliary device according to any one of claims 1 to 4, characterized in that, The front (1211) and / or the back (1212) of the garment include a recess configured to press against the patient’s body surface for placing the breath sound collection unit (110).

6. An atomization system, characterized in that, It includes: The inhalation drug delivery module (300) is configured to deliver drugs to patients via the respiratory tract in a nebulized manner, and is equipped with a flow detection device to acquire time-related drug flow data during patient use; A ventilator (100) is configured to be attached to the surface of the patient’s airway region to collect time-related breath sound / lung sound signals when the patient is using it; An information processing module (200) generates instructions to adjust the inhalation drug delivery module (300) based on information collected by the ventilator (100). Based on the correlation analysis between the respiratory sound / lung sound signals collected by the ventilator (100) and the drug flow data, the information processing module (200) generates adjustment instructions regarding the nebulization position, breathing mode, and / or nebulized drug ratio.

7. The atomization system according to claim 6, characterized in that, The information processing module (200) is configured as follows: Based on the frequency of the breath sound / lung sound signals collected by the ventilator (100), a nebulization flow rate adjustment command related to the patient's respiratory rate adjustment is generated.

8. The atomizing system according to claim 6 or 7, characterized in that, The information processing module (200) is configured as follows: Based on the intensity of the breath sound / lung sound signals collected by the ventilator (100), an nebulized particle adjustment command related to the changes in the patient's sputum and dampness symptoms is generated.

9. The atomizing system according to any one of claims 6 to 8, characterized in that, The information processing module (200) is configured as follows: Based on the abnormal changes in the breath sound / lung sound signals collected by the ventilator (100), adjustment instructions are generated to alleviate the abnormal symptoms caused by nebulization in the patient.

10. The atomizing system according to any one of claims 6 to 9, characterized in that, The information processing module (200) is configured as follows: When connected to a remote medical care terminal, the remote medical care terminal receives one or more respiratory sound / lung sound signals collected by the ventilator (100) from the patient, and controls the inhalation drug delivery module (300) to adjust the drug ratio of the patient's nebulization based on the drug ratio instruction sent by the remote medical care terminal.

11. The atomizing system according to any one of claims 6 to 10, characterized in that, The ventilator (100) includes a breath sound collection unit (110) capable of collecting breath sounds from the patient’s upper respiratory tract and lungs.

12. The atomizing system according to any one of claims 6 to 11, characterized in that, The ventilator (100) further includes an inflatable garment (120) for assisting the patient in adjusting their breathing rate, wherein the inflatable garment (120) is configured to be worn on the patient's body as clothing (121), the clothing (121) including a front (1211), a back (1212) and an inflatable bladder (122) at least incorporated in or on the back (1212), the front (1211) and / or the back (1212) including a recess configured to press against the patient's body surface for placing the breath sound collecting unit (110).

13. The atomizing system according to any one of claims 6 to 12, characterized in that, When the inflatable bladder (122) is inflated so that the clothing (121) being worn presses against the patient's body surface, the breath sound collection unit (110) placed in the recess is able to collect at least the patient's bronchial breath sounds, vesicular breath sounds and / or bronchovesicular breath sounds.

14. The atomizing system according to any one of claims 6 to 13, characterized in that, The inhalation drug delivery module (300) includes a drive unit (310), a drug container (330) regulated by the drive unit (310), and an atomizing unit (320) that turns the drug into an aerosol. The drive unit (310) includes a connector assembly disposed between the drug container (330) and the atomizing unit (320). The connector assembly includes a needle and a suction pump, which are regulated by the information processing module (200). The needle can pierce the drug bottle that is engaged in the drug container (330) and, under the action of the suction pump, cause the drug in the drug bottle to flow into the atomizing unit (320).

15. The atomizing system according to any one of claims 6 to 14, characterized in that, The medication cartridge (330) includes a first medication cartridge (331) and a second medication cartridge (332), which can be individually regulated by the drive unit (310) to administer medication.

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