Composition suitable for skin care
The combination of saccharides, plant proteins, polyglutamic acid, diols, and chelating agents in a cosmetic composition addresses the issues of stickiness and skin affinity, resulting in a smooth, effective skin care product.
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- LOREAL SA
- Filing Date
- 2025-11-27
- Publication Date
- 2026-06-11
Smart Images
Figure IMGF000016_0001_TABLE
Abstract
Description
DESCRIPTIONTITLE OF INVENTION COMPOSITION SUITABLE FOR SKIN CARE TECHNICAL FIELDThe present invention relates to a composition, preferably a cosmetic composition, and more preferably a skin cosmetic composition, which can show a comfortable texture and good skin affinity.BACKGROUND ARTImparting a comfortable texture to skin is one of the key features of cosmetic products, in particular skin care cosmetic products. In order to provide cosmetic products with a comfortable texture, for example, reducing stickiness of the cosmetic products is useful in some cases.Cosmetic products with less stickiness can provide a comfortable texture such as smooth feeling to use.On the other hand, skin affinity is also another key feature of cosmetic products. A good skin affinity of cosmetic products can be linked to the effects of the cosmetic products on the skin. Thus, there remains a need for cosmetic products, in particular skin care cosmetic products, which has a comfortable texture and good skin affinity, while also providing cosmetic effects such as skin care effects.DISCLOSURE OF INVENTIONAn objective of the present invention is to provide a composition which can show a comfortable texture and good skin affinity, while providing cosmetic effects such as skin care effects.The above objective of the present invention can be achieved by a composition, preferably a cosmetic composition, and more preferably a skin cosmetic composition, comprising:(a) at least one skin care active ingredient selected from the group consisting of (al) saccharides, (a2) proteins derived from plants, and mixtures thereof;(b) at least one polyglutamic acid or a salt thereof;(c) at least one diol having at least one carbon chain comprising 7 or more carbon atoms; and (d) at least one chelating agent.The (al) saccharide may be selected from disaccharides, preferably selected from the group consisting of sucrose, lactulose, lactose, maltose, trehalose, cellobiose and a mixture thereof, and more preferably the (al) saccharide is trehalose.The amount of the (al) saccharide(s) in the composition according to the present invention may range from 0.1% to 15% by weight, preferably from 0.5% to 10% by weight, and more preferably from 1% to 5% by weight, relative to the total weight of the composition.The (a2) protein derived from plant may be selected from hydrolyzed plant proteins, preferably selected from the group consisting of hydrolyzed pea protein, hydrolyzed soy protein, hydrolyzed wheat protein, hydrolyzed rice protein, hydrolyzed com protein, recombinant silk protein derived fromplants and mixtures thereof, and more preferably the (a2) protein derived from plant is hydrolyzed rice protein.The amount of the (a2) protein(s) derived from plant(s) in the composition according to the present invention may range from 0.01% to 15% by weight, preferably from 0.05% to 10% by weight, and more preferably from 0.1% to 5% by weight, relative to the total weight of the composition.The (b) polyglutamic acid or a salt thereof may be selected from the group consisting of polyglutamic acid, sodium polyglutamate, and a mixture thereof.The amount of the (b) polyglutamic acid(s) or salt(s) thereof in the composition according to the present invention may range from 0.001% to 3% by weight, preferably from 0.005% to 1% by weight, and more preferably from 0.01% to 0.5% by weight, relative to the total weight of the composition.The (c) diol may have at least one carbon chain comprising from 7 to 14 carbon atoms, preferably from 7 to 12 carbon atoms, more preferably 7 to 10 carbon atoms, and even more preferably 7 or 8 carbon atoms.The (c) diol may have 1 to 3 carbon chains, preferably 1 or 2 carbon chains, and more preferably 1 carbon chain, each carbon chain comprising from 7 to 14 carbon atoms, preferably from 7 to 12 carbon atoms, more preferably 7 to 10 carbon atoms, and even more preferably 7 or 8 carbon atoms.The (c) diol may be selected from the group consisting of 1,8-octanediol, 2-ethyl-1,3-hexanediol, caprylyl glycol, and a mixture thereof, and preferably the (d) diol is caprylyl glycol.The amount of the (c) diol(s) in the composition according to the present invention may range from 0.01% to 15% by weight, preferably from 0.05% to 10% by weight, and more preferably from 0.1% to 5% by weight, relative to the total weight of the composition.The (d) chelating agent may be selected from (poly)amino(poly)carboxylic acids, preferably selected from the group consisting of trisodium ethylenediamine disuccinate, trisodium NTA, pentasodium pentetate, and a mixture thereof, and more preferably the (c) chelating agent is trisodium ethylenediamine disuccinate.The amount of the (d) chelating agent(s) in the composition according to the present invention may range from 0.01% to 5% by weight, preferably from 0.05% to 3% by weight, and more preferably from 0.1% to 1% by weight, relative to the total weight of the composition.The composition according to the present invention may further comprise (e) water.The present invention also relates to a cosmetic process for a keratin material such as skin, comprising applying to the keratin material the composition according to the present invention.BEST MODE FOR CARRYING OUT THE INVENTIONAfter diligent research, the inventors have discovered that it is possible to provide a composition which can show a comfortable texture and good skin affinity, while providing cosmetic effects such as skin care effects.Thus, one aspect of the present invention is a composition comprising:(a) at least one skin care active ingredient selected from the group consisting of (al) saccharides, (a2) proteins derived from plants, and mixtures thereof;(b) at least one polyglutamic acid or a salt thereof;(c) at least one diol having at least one carbon chain comprising 7 or more carbon atoms; and (d) at least one chelating agentThe composition according to the present invention can provide a comfortable texture and good skin affinity, while providing cosmetic effects such as skin care effects.The composition according to the present invention can have a comfortable texture, such as a smooth feeling to use, by reducing the stickiness of the composition. The term “stickiness” here means a property which provides a tacky feeling to the skin.Thus, the composition according to the present invention can provide a comfortable texture during and / or after being applied onto the skin.The composition according to the present invention can also have good skin affinity.The term “skin affinity” here means suitability or compatibility to the skin. Good skin affinity of the composition according to the present invention means that the composition according to the present invention can be suitable well for or compatible well with the surface of the skin.The surface of skin is slightly hydrophobic. The (c) diol having at least one carbon chain comprising 7 or more carbon atoms included in the composition according to the present invention is also slightly hydrophobic, due to a relatively long carbon chain. Thus, it is believed that the (c) diol can contribute to good skin affinity of the composition according to the present invention.Good skin affinity of the composition according to the present invention can contribute to good spreadabillity of the composition during the application of the composition onto the skin and / or smoothness on the skin after the application of the composition onto the skin.The composition according to the present invention is suitable for skin care, because it includes (a) at least one skin care ingredient.Thus, the composition according to the present invention can also provide cosmetic effects such as skin care effects.As a result, the composition according to the present invention can provide good skin finish. Hereinafter, the present invention will be explained in a more detailed manner.[Composition]The composition according to the present invention comprises:(a) at least one skin care active ingredient selected from the group consisting of (al) saccharides, (a2) proteins derived from plants, and mixtures thereof;(b) at least one polyglutamic acid or a salt thereof;(c) at least one diol having at least one carbon chain comprising 7 or more carbon atoms; and (d) at least one chelating agent.(Skin Care Active Ingredient)The composition according to the present invention comprises (a) at least one skin care active ingredient. The (a) skin care active ingredient is selected from the group consisting of (al) saccharides, (a2) proteins derived from plants, and mixtures thereof.< Saccharides>The composition according to the present invention may comprise (al) at least one saccharide. A single type of saccharide may be used, while two or more different types of saccharides may be used in combination.The term “saccharide” here means a polyalcohol composed of one or more glucidic units, and may have at least one carbonyl group. The derivative of a saccharide includes a sugar alcohol which is obtained by reducing one or more carbonyl groups of a saccharide, as well as a saccharide or a sugar alcohol in which the hydrogen atom or atoms in one or more hydroxy groups thereof has or have been replaced with at least one substituent such as an alkyl group, a hydroxyalkyl group, an alkoxy group, an acyl group or a carbonyl group.The saccharide may be selected from the group consisting of monosaccharides, disaccharides, oligosaccharides, polysaccharides, and mixtures thereof.The monosaccharide may be selected from the group consisting of aldoses, ketoses and mixtures thereof.Examples of the aldoses include tetroses such as erythrose, threose; pentoses such as ribose, arabinose, xylose, lyxose; hexoses such as allose, altrose, glucose, mannose, gulose, idose, galactose, and talose; and mixtures thereof.Examples of the ketoses include tetroses such as eiythrulose; pentoses such as xylulose and ribulose; hexoses such as psicose, fructose, sorbose and tagatose; and mixtures thereof.The disaccharide may be selected from reducing sugars and non-reducing sugars.Examples of the disaccharide include sucrose, lactulose, lactose, maltose, trehalose and cellobiose. The oligosaccharides may be composed of 3 to 10 monosaccharides.Examples of the oligosaccharide include flucto-oligosaccharide, malto-oligosaccharide, isomaltooligosaccharide, dextrin, cyclodextrin and mixtures thereof.The polysaccharide may be selected from alginic acid, guar gum, xanthan gum, gum arabic, arabinogalactan, carrageenan, agar, karaya gum, gum tragacanth, tara gum, pectin, locust bean gum, cardolan, jellan gum, dextran, pullulan, hyaluronic acid, cellulose and its derivatives, and mixtures thereof.The derivative of a saccharide may be selected from the group consisting of erythritol, lactitol,maltitol, mannitol, sorbitol and xylitol, in which at least one hydrogen in the hydroxyl groups thereof may have been replaced with at least one substituent such as an alkyl group, a hydroxyalkyl group, an alkoxy group, an acyl group or a carbonyl group.The above saccharides can exist in the form of L or D isomers.The amount of the (al) saccharide(s) in the composition according to the present invention may be 0.1% by weight or more, preferably 0.5% by weight or more, and more preferably 1% by weight or more, relative to the total weight of the composition.The amount of the (al) saccharide(s) in the composition according to the present invention may be 15% by weight or less, preferably 10% by weight or less, and more preferably 5% by weight or less, relative to the total weight of the composition.The amount of the (al) saccharide(s) in the composition according to the present invention may be from 0.1% to 15% by weight, preferably from 0.5% to 10% by weight, and more preferably from 1% to 5% by weight, relative to the total weight of the composition.< Plant Proteins>The composition according to the present invention may comprise (a2) at least one protein derived from plant(s). A single type of such a protein may be used, while two or more different types of such proteins may be used in combination.The protein derived from plant(s) may be polypeptides which can be obtained from plant(s) such as soy beans, peas, wheat, rice, coms and sesame. The protein may be subjected to hydrolysis. The hydrolysis can be performed by conventionally known processes using, for example, acids or enzymes. The protein derived from plant(s) may also be polypeptides which can be obtained via industrial biotechnology process such as gene recombination and fermentation for natural potent carbon-sources such as com starch.It is preferable that the (a2) protein derived from plant(s) be selected from hydrolyzed plant proteins.It is more preferable that the (a2) protein derived from plant(s) be selected from the group consisting of hydrolyzed pea protein, hydrolyzed soy protein, hydrolyzed wheat protein, hydrolyzed rice protein, hydrolyzed com protein, recombinant silk protein derived from plant(s), and a mixture thereof.It is even more preferable that the (a2) protein derived from plant(s) be hydrolyzed rice protein. The proteins may comprise acidic amino acid such as aspartic acid and glutamic acid, and basic amino acid such as arginine, histidine and lysine.The hydrolyzed pea protein can be prepared by hydrolysis of peas (Pisum sativum L.). As the hydrolyzed pea protein, a commercial product such as Promois® WJ or Promois® WJ-SP from Seiwa Kasei Co., Ltd., which is an aqueous solution of pea protein or powdered pea protein, respectively with an average molecular weight of about 500, may be used. The hydrolyzed soy protein can be prepared by hydrolysis of soys (Glycine max). As the hydrolyzed soy protein, a commercial product such as Promois® WS or Promois® WS-HSP from Seiwa Kasei Co., Ltd.,which is an aqueous solution of soy protein or powdered soy protein, respectively with an average molecular weight of about 700, may be used. The hydrolyzed wheat protein can be prepared by hydrolysis of wheats (Triticum). As the hydrolyzed wheat protein, a commercial product such as Promois® WG or Promois® WG-SP from Seiwa Kasei Co., Ltd., which is an aqueous solution of wheat protein or powdered wheat protein, respectively with an average molecular weight of about 700, may be used. The hydrolyzed rice protein can be prepared by hydrolysis of rice (Oryza sativa). As the hydrolyzed rice protein, a commercial product such as Nutripeptides® from Silab., which is an aqueous solution of rice protein, may be used. As the mixture of hydrolyzed wheat protein, hydrolyzed com protein, and hydrolyzed soy protein, a commercial product such as Keraplant from TRI-K, which is an aqueous solution of wheat protein, corn protein, and soy protein, may be used. As the plant origin silk, a commercial product such as Silkgel Neo® from Givaudan, which is an aqueous gel of silk produced by industrial biotechnology processes with fermentation may be used.The amount of the (a2) protein(s) derived from plant(s) in the composition according to the present invention may be 0.01% by weight or more, preferably 0.05% by weight or more, and more preferably 0.1% by weight or more, relative to the total weight of the composition.The amount of the (a2) protein(s) derived from plant(s) in the composition according to the present invention may be 15% by weight or less, preferably 10% by weight or less, and more preferably 5% by weight or less, relative to the total weight of the composition.The amount of the (a2) protein(s) derived from plant(s) in the composition according to the present invention may be from 0.01% to 15% by weight, preferably from 0.05% to 10% by weight, and more preferably from 0.1% to 5% by weight, relative to the total weight of the composition.(Polyglutamic Acid or Salt Thereof)The composition according to the present invention comprises (b) at least one polyglutamic acid or a salt thereof. A single type of polyglutamic acid or a salt thereof may be used, while two or more different types of polyglutamic acids or salts thereof may be used in combination.The (b) polyglutamic acid or a salt thereof may have a chemical structure represented by the following chemical formula (1):ROOC-CH2CH2-CH(-COOR)-NH-[CO-CH2CH2-CH(-COOR)-NH-]n-CO-CH2CH2-CH(-COOR)-NH2(1)in which R independently denotes a hydrogen atom, an alkali metal atom such as sodium atom and potassium atom, or an ammonium group such as tetramethylammoium group and tetraethylammonium group, andn is an integer of 2 or more, preferably 4 or more, and more preferably 6 or more.The polyglutamic acid or a salt thereof represented by the above chemical formula (1) may be referred to as y-polyglutamic acid or a salt thereof, because the carboxylic group at the y-position and the amino group at the a-position form a peptide bond.It may be preferable that the molecular weight of the (b) polyglutamic acid or a salt thereof be 1000 or more, and that the degree of polymerization be 8 or more (“n” in the above chemicalformula (1) is 6 or more).It may be more preferable that the molecular weight of the (b) polyglutamic acid or a salt thereof be 100,000 or more, and that the polymerization degree be 770 or more (“n” in the above chemical formula (1) is 768 or more).It may be even more preferable that the molecular weight of the (b) polyglutamic acid or a salt thereof be 500,000 or more, and that the polymerization degree be 3840 or more (“n” in the above chemical formula (1) is 3838 or more).There is no upper limit for the molecular weight of the (b) polyglutamic acid or a salt thereof. However, the molecular weight of the (b) polyglutamic acid or a salt thereof may be 5000000 or less, and the degree of polymerization may be 38500 or less (“n” in the above chemical formula (1) is 38498 or less), and preferably the molecular weight the (b) polyglutamic acid or a salt thereof may be 3000000 or less, and the degree of polymerization may be 23080 or less (“n” in the above chemical formula (1) is 23078 or less).The glutamic acid that is a constituent amino acid of the (b) polyglutamic acid or a salt thereof may be D-form, L-form or a racemic form. However, in consideration of the availability in the market, biocompatibility and biodegradability, the use of polyglutamic acid composed only of L-form glutamic acids or polyglutamic acid composed of a mixture of L- and D- form glutamic acids may be preferable. However, polyglutamic acid composed of D-form glutamic acids having the same effect and low degradability can also be used.The production method of the (b) polyglutamic acid or a salt thereof is not particularly limited. For example, an organic synthesis method using a peptide synthesizer, an organic synthesis method by polymerization reaction of glutamate N-carboxylic anhydride, an organic synthesis by polymerization reaction of N-benzyloxycarbonyl glutamic anhydride. On the other hand, microorganisms belonging to the genus Bacillus having the ability to produce y-polyglutamic acid (particularly Bacillus subtilis, Bacillus anthracis, Bacillus licheniformis, Bacillus licheniformis, Bacillus megaterium having the ability to produce y-polyglutamic acid) can also be used for fermentation methods for producing the (b) polyglutamic acid or a salt thereof.As a medium used in the fermentation method, in addition to a natural medium composed of natural products such as shochu distillation waste liquid medium and soybean extract medium, any synthetic medium or any semi-synthetic medium constituted by any one of the following ingredients:carbon sources such as glucose, fructose, galactose, sucrose, maltose, mannose, lactose, glycerol, and starch;inorganic nitrogen sources such as ammonium sulfate, ammonium phosphate and ammonium hydrochloride;organic nitrogen sources such as glutamic acid or salts thereof, aspartic acid or salts thereof major inorganic salts such as sodium chloride, magnesium sulfate, monopotassium phosphate, phosphorus and disodium phosphate;trace inorganic salts containing atoms such as iron, copper, zinc, cobalt, nickel, boron, manganese, molybdenum, tin, selenium, silicon, arsenic, vanadium, chromium, and fluorine;vitamins such as biotin, nicotinic acid amide, calcium pantothenate, thiamine, riboflavin and pyridoxine hydrochloride;organic acids such as citric acid, tartaric acid, malic acid, and glycolic acid, andnatural product extracts such as yeast extract, meat extract, potato extract, tomato extract, and soybean peptide,at any concentration may be used.The culture conditions of the microorganism may be set in the range of from 20°C to 37°C with respect to the temperature, and may be further controlled during the microorganism growth process and polyglutamic acid production process. The pH may be set in the range of from 5.0 to 8.0, and may be further controlled during the microorganism growth process and polyglutamic acid production process.As a method for extracting and purifying the (b) polyglutamic acid or a salt thereof from the culture solution after completion of the culture, known methods such as an acid precipitation method, a solvent precipitation method, and a membrane purification method can be arbitrarily selected.It is preferable, as the (b) polyglutamic acid or a salt thereof, to use polyglutamic acid or an alkaline metal salt thereof such as sodium polyglutamate.Thus, it is preferable that the (b) polyglutamic acid or a salt thereof be selected from the group consisting of polyglutamic acid, sodium polyglutamate, and a mixture thereof.As the (b) polyglutamic acid or a salt thereof, a commercially available product may be used. As examples of the (b) polyglutamic acid or a salt thereof, mention may be made of, Hyafactor™-PGA-HM sold by Bloomage Biotechnology Co., Ltd. in China, and Bio-PGA Solution HE, HB, LB and LE, and Bio PGA Na powder, sold by Ichimaru Pharcos in Japan.The amount of the (b) polyglutamic acid(s) or salt(s) thereof in the composition according to the present invention may be 0.001% by weight or more, preferably 0.005% by weight or more, and more preferably 0.01% by weight or more, relative to the total weight of the composition.The amount of the (b) polyglutamic acid(s) or salt(s) thereof in the composition according to the present invention may be 3% by weight or less, preferably 2% by weight or less, and more preferably 1% by weight or less, relative to the total weight of the composition.The amount of the (b) polyglutamic acid(s) or salt(s) thereof in the composition according to the present invention may range from 0.001% to 3% by weight, preferably from 0.005% to 2% by weight, and more preferably from 0.01% to 1% by weight, relative to the total weight of the composition.(Diol)The composition according to the present invention comprises (c) at least one diol having at least one carbon chain comprising 7 or more carbon atoms. Two or more such (c) diols may be used in combination. Thus, a single type of such (c) diol or a combination of different types of such (c) diols may be used.Hereafter, (c) at least one diol having at least one carbon chain comprising 7 or more carbon atoms may be simply referred to as “(c) diol”.The term “diol” here means a compound which has two alcohol functions. In other words, diolis an alcohol having two hydroxy groups.The number of carbon atoms in the carbon chain in the (c) diol is 7 or more, and preferably 8 or more. On the other hand, the number of carbon atoms in the carbon chain in the (c) diol may be 14 or less, preferably 12 or less, and more preferably 10 or less. Thus, the (c) diol may have at least one carbon chain comprising from 7 to 14 carbon atoms, preferably from 7 to 12 carbon atoms, and more preferably 7 to 10 carbon atoms. It may be even more preferable that the number of carbon atoms in the carbon chain in the (c) diol be 7 or 8.The carbon chain comprising 7 or more carbon atoms in the (c) diol may be straight or branched, preferably straight. The carbon chain may not be interrupted by a heteroatom such as an oxygen atom, a sulfur atom and a nitrogen atom. Thus, the carbon chain may comprise consecutive carbon atoms.The number of the carbon chain comprising 7 or more carbon atoms in the (c) diol is not limited. It may be preferable that the number of the carbon chain comprising 7 or more carbon atoms in the (c) diol be 1 to 3, more preferably 1 or 2, and even more preferable 1.The total number of carbon atoms in the (c) diol may be 7 or more, and preferably 8 or more. On the other hand, the total number of carbon atoms in the (c) diol may be 14 or less, preferably 12 or less, and more preferably 10 or less. Thus, the total number of carbon atoms in the (c) diol may be from 7 to 14, preferably from 7 to 12, and more preferably from 7 to 10. It may be even more preferable that the total number of carbon atoms in the (c) diol be 7 or 8.The (c) diol(s) having at least one carbon chain comprising 7 or more carbon atoms may have a divalent straight or branched hydrocarbon group. The divalent straight or branched hydrocarbon group which may be present in the (c) diol may be saturated or unsaturated. It is preferable that the (c) diol comprise a divalent straight or branched saturated hydrocarbon group, and more preferably a straight or branched alkylene group, such as a heptylene group, and an octylene group.The (c) diol(s) having at least one carbon chain comprising 7 or more carbon atoms may have a linear, branched or cyclic molecular structure, as long as it has the carbon chain comprising 7 or more carbon atoms.The (c) diol(s) having at least one carbon chain comprising 7 or more carbon atoms may be a C7-10 diol, preferably C7-9 diol, and more preferably C7-8 diol, comprising 2 hydroxy groups.It is preferable that the (c) diol having at least one carbon chain comprising 7 or more carbon atoms be selected from the group consisting of 1,8-octanediol, 2-ethyl-1,3-hexanediol, caprylyl glycol, and a mixture thereof.It is more preferable that the (c) diol having at least one carbon chain comprising 7 or more carbon atoms be caprylyl glycol.The amount of the (c) diol(s) in the composition according to the present invention is more than 0.01% by weight, preferably 0.05% by weight or more, and more preferably 0.1% by weight or more, relative to the total weight of the composition.The amount of the (c) diol(s) in the composition according to the present invention may be 15%by weight or less, preferably 10% by weight or less, and more preferably 5% by weight or less, relative to the total weight of the composition.The amount of the (c) diol(s) in the composition according to the present invention may be more than 0.01% weight and 15% by weight or less, preferably from 0.05% to 10% by weight, and more preferably from 0.1% to 5% by weight, relative to the total weight of the composition.(Chelating Agent)The composition according to the present invention comprises (d) at least one chelating agent. A single type of a chelating agent may be used, but two or more different types of chelating agents may be used in combination.As the (d) chelating agent, mention may be made of(i) aminocarboxylic acids such as the compounds having the following INCI name:diethylenetriaminepentaacetic acid (DTPA), ethylenediaminedisuccinic acid (EDDS) and trisodium ethylenediamine disuccinate such as Octaquest E30 from Octel, ethylenediaminetetraacetic acid (EDTA), ethylenediamine-N, N'-diglutaric acid (EDDG), glycinamide-N, N'-disuccinic acid (GADS), 2-hydroxypropylenediamine-N, N'-disuccinic acid (HPDDS), ethylenediamine-N, N'-bis(ortho-hydroxyphenylacetic acid) (EDDHA), N, N'-bis(2-hydroxybenzyl)ethylenediamine-N, N'-diacetic acid (EfBED), nitrilotriacetic acid (NTA), methylglycine diacetic acid (MGDA), N-2-hydroxyethyl-N, N-diacetic acid and glyceryl imino diacetic acid (as described in documents EP-A-317542 and EP-A- 399 133), iminodiacetic acid-N-2-hydroxypropyl sulfonic acid and aspartic acidN- carboxymethyl N-2-hydroxypropyl-3-sulfonic acid (as described in EP-A-516 102), beta- alanine-N, N'-diacetic acid, aspartic acid-N, N'-diacetic acid and aspartic acid-N- monoacetic acid (described in EP-A-509382), chelating agents based on iminodisuccinic acid (IDSA) (as described in EP-A-509382), ethanoldiglycine acid, phosphonobutane tricarboxylic acid, such as the compound sold by Bayer under the reference Bayhibit AM, tetrasodium glutamate diacetate (GLDA) such as Dissolvine GL38 or 45 S from Akzo Nobel,(ii) chelating agents based on mono- or polyphosphonic acid, such as the compounds having the following INCI name: diethylenetriaminepenta(methylenephosphonic acid) (DTPMP), ethane- 1 -hydroxy- 1,1,2-triphosphonic acid (E1HTP),
[0263] ethane-2- hydroxy-l,l,2-triphosphonic acid (E2HTP), ethane- 1 -hydroxy- 1,1-diphosphonic acid (EHDP), ethane- 1,1,2-triphosphonic acid (ETP), ethylenediaminetetramethylenephosphonic acid (EDTMP), and hydroxyethane- 1,1- diphosphonic acid (HEDP), and(iii) chelating agents based on polyphosphoric acid, such as the compounds having the following INCI name: sodium tripolyphosphate (STP), tetrasodium diphosphate, hexametaphosphoric acid, sodium metaphosphate, phytic acid, salts and derivatives thereof,andmixtures thereof.It is preferable that the (d) chelating agent be biodegradable. In this sense, EDTA which is not biodegradable, is not preferable as the (d) chelating agent. Thus, it is preferable not to use EDTA as the (d) chelating agent. Furthermore, it is preferable that the composition according to the present invention is free from EDTA.The term “free from” here means that the composition according to the present invention may contain a limited amount of EDTA. However, it is preferable that the amount of EDTA be limited such that it is less than 1% by weight, more preferably less than 0.1% by weight, and even more preferably less than 0.01 % by weight, relative to the total weight of the composition. It is most preferable that the composition according to the present invention comprise no EDTA. It is preferable that the (d) chelating agent be selected from (poly)amino(poly)carboxylic acids, i.e., aminocarboxylic acids with one or more amino moieties and / or one or more carboxy moieties.It is more preferable that the (d) chelating agent be selected from the group consisting of trisodium ethylenediamine disuccinate, trisodium NTA, pentasodium pentetate, and a mixture thereof. It is even more preferable that the (d) chelating agent be trisodium ethylenediamine disuccinate. The amount of the (d) chelating agent(s) in the composition according to the present invention may be 0.01% by weight or more, preferably 0.05% by weight or more, and more preferably 0.1% by weight or more, relative to the total weight of the composition.The amount of the (d) chelating agent(s) in the composition according to the present invention may be 5% by weight or less, preferably 3% by weight or less, and more preferably 1% by weight or less, relative to the total weight of the composition.The amount of the (d) chelating agent(s) in the composition according to the present invention may range from 0.01% to 5% by weight, preferably from 0.05% to 3% by weight, more preferably from 0.1% to 1% by weight, relative to the total weight of the composition.(Water)The composition according to the present invention may comprise (e) water.The amount of (e) water in the composition according to the present invention may be 50% by weight or more, preferably 60% by weight or more, and more preferably 70% by weight or more, relative to the total weight of the composition.The amount of (e) water in the composition according to the present invention may be 95% by weight or less, preferably 90% by weight or less, and more preferably 85% by weight or less, relative to the total weight of the composition.The amount of (e) water in the composition according to the present invention may range from 50% to 95% by weight, preferably from 60% to 90% by weight, more preferably from 70% to 85% by weight, relative to the total weight of the composition.(pH)The pH of the composition according to the present invention may be less than 7.0, preferably less than 6.5, and more preferably less than 6.3.The pH of the composition according to the present invention may be 3.0 or more, preferably 3.5 or more, and more preferably 4.0 or more.For example, the pH of the composition according to the present invention may be from 3.0 to less than 7.0, preferably from 3.5 to less than 6.5, and more preferably from 4.0 to less than 6.3.The pH of the composition according to the present invention may be adjusted by adding at least one alkaline agent and / or at least one acid or a salt thereof. The pH of the composition according to the present invention may also be adjusted by adding at least one buffering agent.(Embodiments)According to a preferred embodiment, the composition according to the present invention comprises, relative to the total weight of the composition:(a) at least one skin care active ingredient selected from the group consisting of (al) saccharides, (a2) proteins derived from plants, and mixtures thereof;0.001% to 3% by weight of (b) at least one polyglutamic acid or a salt thereof;0.01% to 15% by weight of (c) at least one diol having at least one carbon chain comprising 7 or more carbon atoms; and0.01% to 5% by weight of (d) at least one chelating agent,whereinthe amount of the (al) saccharide(s) is 0.1% to 15% by weight, andthe amount of the (a2) protein(s) derived from plant(s) is 0.01% to 15% by weight.According to a more preferred embodiment, the composition according to the present invention comprises, relative to the total weight of the composition:(a’) at least one skin care active ingredient selected from the group consisting of (al ’) disaccharides, (a2’) hydrolyzed plant proteins, and mixtures thereof;0.005% to 2% by weight of (b’) at least one polyglutamic acid or an alkaline metal salt thereof;0.05% to 10% by weight of (c’) at least one diol having at least one carbon chain comprising 7 or more carbon atoms, selected from the group consisting of 1,8-octanediol, 2-ethyl-1,3-hexanediol, caprylyl glycol, and a mixture thereof; and0.05% to 3% by weight of (d’) at least one chelating agent selected from (poly)amino(poly)carboxylic acids,whereinthe amount of the (al ’) disaccharide(s) is 0.5% to 10% by weight, andthe amount of the (a2’) protein(s) derived from plant(s) is 0.05% to 10% by weight.According to an even more preferred embodiment, the composition according to the present invention comprises, relative to the total weight of the composition:(a”) at least one skin care active ingredient selected from the group consisting of (al ”) trehalose, (a2”) proteins derived from plants, selected from the group consisting of hydrolyzed pea protein, hydrolyzed soy protein, hydrolyzed wheat protein, hydrolyzed rice protein, hydrolyzed corn protein, recombinant silk protein derived from plants and mixtures thereof, and mixtures thereof;0.01 % to 1 % by weight of (b”) at least one polyglutamic acid or a salt thereof, selected from the group consisting of polyglutamic acid, sodium polyglutamate, and a mixture thereof;0.1% to 5% by weight of (c”) at least one diol having at least one carbon chain comprising 7 or more carbon atoms, being caprylyl glycol; and0.1% to 1% by weight of (d”) at least one chelating agent, being trisodium ethylenediamine disuccinate,whereinthe amount of the (al ”) trehalose is 1% to 5% by weight, andthe amount of the (a2”) protein(s) derived from plant(s) is 0.1% to 5% by weight.(Additional Optional Ingredient)The composition according to the present invention may comprise, in addition to the aforementioned ingredients, optional ingredient(s) typically employed in cosmetics, specifically, polyols other than the ingredient (c); organic or inorganic UV filters; surfactants or emulsifiers, hydrophilic or lipophilic thickeners; coloring agents; cationic polymers, anionic polymers, amphoteric polymers and nonionic polymers; silicones and silicone derivatives; natural extracts derived from animals or vegetables; oils; preservatives; and the like, within a range which does not impair the effects of the present invention. The composition according to the present invention may further comprise at least one organic solvent. The organic solvent is preferably water miscible. As the organic solvent, there may be mentioned, for example, C1-C4 alkanols, such as ethanol and isopropanol; aromatic alcohols such as benzyl alcohol and phenoxyethanol; analogous products; and mixtures thereof.The organic solvents may be present in an amount ranging from 0.01% by weight or more, preferably 0.1% by weight or more, and more preferably 1% by weight or more, relative to the total weight of the composition according to the present invention.The organic solvents may be present in an amount ranging from 15% by weight or less, preferably 10% by weight or less, and more preferably 5% by weight or less, relative to the total weight of the composition according to the present invention.The organic solvents may be present in an amount ranging from 0.01% to 15% by weight, preferably from 0.1% to 10% by weight, and more preferably from 1% to 5% by weight, relative to the total weight of the composition according to the present invention.The composition according to the present invention may include a limited amount of oil(s).The amount of oil(s) in the composition according to the present invention may be 1% by weight or less, preferably 0.5% by weight or less, and more preferably 0.1% by weight or less, relative to the total weight of the composition. It may be particularly preferable that the composition according to the present invention include 0.01% by weight or less of oil, relative to the total weight of the composition.Preferably, the composition according to the present invention includes a very limited amount of silicone(s).Preferably, the amount of silicone(s), such as organopolysiloxanes, in the composition according to the present invention is 1% by weight or less, preferably 0.1% by weight or less, and more preferably 0.01% by weight or less, relative to the total weight of the composition. It is particularly preferable that the composition according to the present invention include no silicone. (Preparation)The composition according to the present invention can be prepared by mixing the essential ingredient(s) as explained above, and optional ingredient(s), if necessary, as explained above. The method and means to mix the above essential and optional ingredients are not limited. Anyconventional method and means can be used to mix the above essential and optional ingredients to prepare the composition according to the present invention. The conventional method and means include a homogenizer, for example, a turbine mixer.(Cosmetic Application)The composition according to the present invention may be intended to be used as a cosmetic composition. Thus, the cosmetic composition according to the present invention may be intended for application onto a keratin material.Keratin material here means a material containing keratin as a main constituent element, and examples thereof include the skin, scalp, nails, lips, hair, and the like. Thus, it is preferable that the cosmetic composition according to the present invention be used as a cosmetic composition for a keratin material, such as skin.Thus, the cosmetic composition according to the present invention may be a skin cosmetic composition, preferably a skin care composition or a skin makeup composition, and more preferably a skin care composition.The composition according to the present invention is suitable as a skin care cosmetic composition, because the composition comprises the (a) skin care active ingredient(s). For example, the composition according to the present invention can be used for moisturizing the skin. It is preferable that the composition according to the present invention be a leave-on type. In other words, it is preferable that the composition according to the present invention be used, on a keratin material such as skin, without being rinsing off. Thus, it is preferable that the composition according to the present invention is not a cleansing composition.(Form)The composition according to the present invention may be in various forms. For example, the composition according to the present invention can be in the form of a solution, an emulsion, a dispersion and the like.The composition according to the present invention can be in the form of a fluid such as a liquid at an ambient temperature (25°C) and under atmospheric pressure (760 mm Hg).The composition according to the present invention may be transparent or translucent.[Cosmetic Process and Use]The present invention also relates to a cosmetic process for a keratin material such as skin, comprising: applying to the keratin material the composition according to the present invention. The cosmetic process here means a non-therapeutic cosmetic method for caring for and / or making up the surface of a keratin material such as skin.The present invention may also relate to a use of a combination of:(a) at least one skin care active ingredient selected from the group consisting of (al) saccharides, (a2) proteins derived from plants, and mixtures thereof;(b) at least one polyglutamic acid or a salt thereof;(c) at least one diol having at least one carbon chain comprising 7 or more carbon atoms; and (d) at least one chelating agent,in a compositionin order for the composition to show reduced stickiness and improved skin affinity.The composition recited in the above use may include any of the optional ingredients explained above, such as (e) water.The above explanations regarding the (a) skin care active ingredient, the (b) polyglutamic acid or a salt thereof, the (c) diol having at least one carbon chain comprising 7 or more carbon atoms, and the (d) chelating agent, as well as optional ingredients such as the (e) water, for the composition according to the present invention, can apply to those in the above use according to the present invention.EXAMPLESThe present invention will be described in more detail by way of examples, which however should not be construed as limiting the scope of the present invention.Examples 1-2 and Comparative Examples 1-8[Preparation]The following compositions according to Examples 1-2 and Comparative Examples 1-8, shown in Table 1, were prepared by mixing the ingredients shown in Table 1. The symbols such as (al ) and (a2) in Table 1 correspond to those in the claims.The numerical values for the amounts of the components shown in Table 1 are all based on “% by weight” as raw materials. The term “0.1AM” in Table 1 means that the amount of the raw material including the ingredient (c) was such that the amount of the active material (hydrolyzed soy protein) in the composition was 0.1% by weight, relative to the total weight of the composition.Table 1Comp. Comp. Comp. Comp. Comp. Comp. Comp. Comp. Ingredient Ex. 1 Ex.2Ex. 1 Ex. 2 Ex. 3 Ex. 4 Ex. 5 Ex. 6 Ex. 7 Ex. 8 qsp qsp qsp qsp qsp qsp qsp qsp qsp qsp (e) Water100 100 100 100 100 100 100 100 100 100 Glycerin 5 5 5 5 5 5 5 5 5 5 Butylene Glycol 3 3 3 3 3 3 3 3 3 3 (0 Caprylyl Glycol 0.2 0.2 0.2 ** 0.2 0.2 0.2 0.2 Chlorphenesin 0.27 0.27 0.27 0.27 0.27 0.27 0.27 0.27 0.27 0.27 Propanediol 10 10 10 10 10 10 10 10 10 10 Trisodium Ethylenediamine(d) 0.25 0.25 0.25 0.25 - 0.25 0.25 - 0.25 - Disuccinate(b) Sodium Polyglutamate*10.01 0.01 0.01 0.01 - 0.01 0.01 0.01(al) Trehalose*23 3 3 3 *» •* * *• (a2) Hydrolyzed Rice Protein*3* 0.1AM * - • 0.1AM 0.1AM 0.1AM * pH adjuster qs qs qs qs qs qs qs qs qs qs Contact Angle (°) 58.9 46.3 59.9 93.3 64.8 61.6 72.4 60.3 65.5 94.3 Skin Affinity Good Good Good Poor Fair Fair Poor Fair Fair PoorStickiness Good Good Fair Fail* Good Poor Good Good Poor Good AM: Active Material*1: sold by Bloomage Biotechnology Co., Ltd. under the commercial name of Hyafactor™-PGA Sodium Polyglutamate (PGA-HM)*2: sold by Nagase Vita Co., Ltd. under the commercial name of Trehalose 100*3: sold by Silab under the commercial name of Nutripeptides®[Evaluations](Contact Angle)The same amount of each of the compositions according to Examples 1-2 and Comparative Examples 1-8 was dropped on the surface of an artificial skin plate (Bioskin plate with smooth surface from Beaulax) The contact angle of the droplet on the artificial skin plate was measured.. The measurement and analysis was conducted with DATAPHYSICS OCA 15 PLUS Optical Contact Angle Measuring Device with SCA20 software. The measurement was repeated 3 times, and the measured 6 values were averaged.The results are shown in Table 1.(Skin Affinity)Based on the values of the contact angle measured as above, the skin affinity of each of the compositions according to Examples 1-2 and Comparative Examples 1-8 was evaluated in accordance with the following criteria.Good: less than 60°Fair: 60° or more and less than 70°Poor: 70° or moreThe results are shown in Table 1.(Stickiness)Four panelists evaluated the texture, in terms of stickiness, of each of the compositions according to Examples 1-2 and Comparative Examples 1-8 at the timing of after application of the composition. Specifically, each panelist applied each composition on his or her hand and spread it to evaluated stickiness, and scored from 1 (low) to 3 (high). The scores were averaged. The averaged score was then classified in the following three categories based on the average of the score.Good: from 2.5 to 3Fair: from 2.0 to less than 2.5Poor: from 1.0 to less than 2.0The results are shown in Table 1.(Summary)As is clear from Table 1, the compositions according to Examples 1 and 2, which included the ingredients (al) or (a2) as well as the ingredients (b) to (d), provided good skin affinity and less stickiness.On the other hand, the compositions according to Comparative Examples 1-8, which did not include at least one of the ingredients (a) to (d), could not provide good skin affinity and showed more stickiness.
Claims
CLAIMS1. A composition, preferably a cosmetic composition, and more preferably a skin cosmetic composition, comprising:(a) at least one skin care active ingredient selected from the group consisting of (a 1 ) saccharides, (a2) proteins derived from plants, and mixtures thereof;(b) at least one polyglutamic acid or a salt thereof;(c) at least one diol having at least one carbon chain comprising 7 or more carbon atoms; and(d) at least one chelating agent.
2. The composition according to Claim 1, wherein the (al) saccharide is selected from disaccharides, preferably selected from the group consisting of sucrose, lactulose, lactose, maltose, trehalose, cellobiose and a mixture thereof, and more preferably is trehalose.
3. The composition according to Claim 1 or 2, wherein the amount of the (al) saccharide(s) in the composition ranges from 0.1 % to 15% by weight, preferably from 0.5% to 10% by weight, and more preferably from 1% to 5% by weight, relative to the total weight of the composition.
4. The composition according to any one of Claims 1 to 3, wherein the (a2) protein derived from plant is selected from hydrolyzed plant proteins, preferably selected from the group consisting of hydrolyzed pea protein, hydrolyzed soy protein, hydrolyzed wheat protein, hydrolyzed rice protein, hydrolyzed com protein, recombinant silk protein derived from plants and mixtures thereof, and more preferably is hydrolyzed rice protein.
5. The composition according to any one of Claims 1 to 4, wherein the amount of the (a2) protein(s) derived from plant(s) in the composition ranges from 0.01% to 15% by weight, preferably from 0.05% to 10% by weight, and more preferably from 0.1% to 5% by weight, relative to the total weight of the composition.
6. The composition according to any one of Claims 1 to 5, wherein the (b) polyglutamic acid or a salt thereof is selected from the group consisting of polyglutamic acid, sodium polyglutamate, and a mixture thereof.
7. The composition according to any one of Claims 1 to 6, wherein the amount of the (b) polyglutamic acid(s) or salt(s) thereof in the composition ranges from 0.001% to 3% by weight, preferably from 0.005% to 2% by weight, and more preferably from 0.01% to 1% by weight, relative to the total weight of the composition.
8. The composition according to any one of Claims 1 to 7, wherein the (c) diol has at least one carbon chain comprising from 7 to 14 carbon atoms, preferably from 7 to 12 carbon atoms, more preferably 7 to 10 carbon atoms, and even more preferably 7 or 8 carbon atoms.
9. The composition according to any one of Claims 1 to 8, wherein the (c) diol has 1 to 3 carbon chains, preferably 1 or 2 carbon chains, and more preferably 1 carbon chain, each carbon chain comprising from 7 to 14 carbon atoms, preferably from 7 to 12 carbon atoms, more preferably 7 to 10 carbon atoms, and even more preferably 7 or 8 carbon atoms.
10. The composition according to any one of Claims 1 to 9, wherein the (c) diol is selected from the group consisting of 1,8-octanediol, 2-ethyl-1,3-hexanediol, caprylyl glycol, and a mixture thereof, and preferably is caprylyl glycol.
11. The composition according to any one of Claims 1 to 10, wherein the amount of the (c) diol(s) in the composition ranges from 0.01% to 15% by weight, preferably from 0.05% to 10% by weight, and more preferably from 0.1% to 5% by weight, relative to the total weight of the composition.
12. The composition according to any one of Claims 1 to 11, wherein the (d) chelating agent is selected from (poly)amino(poly)carboxylic acids, preferably selected from the group consisting of trisodium ethylenediamine disuccinate, trisodium NTA, pentasodium pentetate, and a mixture thereof, and more preferably is trisodium ethylenediamine disuccinate.
13. The composition according to any one of Claims 1 to 12, wherein the amount of the (d) chelating agent(s) in the composition ranges from 0.01% to 5% by weight, preferably from 0.05% to 3% by weight, and more preferably from 0.1% to 1% by weight, relative to the total weight of the composition.
14. The composition according to any one of Claims 1 to 13, wherein the composition further comprises (e) water.
15. A cosmetic process for a keratin material such as skin, comprising applying to the keratin material the composition according to any one of Claims 1 to 14.