Method for increasing intradermal retention amount of polypeptide in cosmetic product, and Anti-aging cosmetic product

By forming a viscous reverse micelle structure in cosmetics to transport peptides, the problem of peptides' inability to penetrate the stratum corneum is solved, achieving efficient retention of peptides in the skin and enhancing anti-aging effects, while avoiding skin damage and providing safety.

WO2026124206A1 Publication Date: 2026-06-18GUANGDONG MARUBI BIOLOGICAL TECH CO LTD
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
GUANGDONG MARUBI BIOLOGICAL TECH CO LTD
Filing Date
2025-11-25
Publication Date
2026-06-18

AI Technical Summary

⚠Technical Problem

Peptides in existing cosmetics have difficulty penetrating the natural lipid barrier of the stratum corneum, resulting in limited intradermal retention and poor anti-aging effects. Furthermore, the use of oil-soluble surfactants in existing methods may damage the skin and has low biocompatibility.

⚗Method used

Aqueous mixtures are prepared by mixing peptides with water, and oil-phase mixtures are prepared by mixing peptides with phospholipids, oils and antioxidants to form viscous reverse micelle structures. This allows peptides to be transported below the stratum corneum. The viscous reverse micelle structure is used as a transporter for peptides to increase intradermal retention.

🎯Benefits of technology

It effectively increases the amount of peptides retained in the skin, enhances the anti-aging effects of anti-aging cosmetics, avoids damage to the skin, and improves biosafety.

✦ Generated by Eureka AI based on patent content.

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Abstract

A method for increasing the intradermal retention amount of a polypeptide in a cosmetic product, and an anti-aging cosmetic product. The method for increasing the intradermal retention amount of a polypeptide in a cosmetic product comprises: mixing a polypeptide with water to prepare an aqueous phase mixture; mixing a phospholipid, grease and an antioxidant to prepare an oil phase mixture; and dropwise adding the aqueous phase mixture to the oil phase mixture to form a viscous reverse micelle structure. The anti-aging cosmetic product comprises the viscous reverse micelle structure formed from a polypeptide raw material.
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