Method for producing l-valine

WO2026124644A1PCT designated stage Publication Date: 2026-06-18MEIHUA BIOTECH LANGFANG CO LTD
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
MEIHUA BIOTECH LANGFANG CO LTD
Filing Date
2025-12-12
Publication Date
2026-06-18

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  • Figure PCTCN2025142124-FTAPPB-I100001
    Figure PCTCN2025142124-FTAPPB-I100001
  • Figure PCTCN2025142124-FTAPPB-I100002
    Figure PCTCN2025142124-FTAPPB-I100002
  • Figure PCTCN2025142124-FTAPPB-I100003
    Figure PCTCN2025142124-FTAPPB-I100003
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Abstract

Provided is a modified bacterium for producing L-valine. Compared with a non-modified bacterium, a genome comprises one or more modifications having enhanced activity of LrpP139L, and / or LeuDHV22I, and / or ilvC, ilvD, and / or ilvE, and the modified bacterium can be produced under anaerobic and aerobic conditions. In addition, also provided is a method for increasing L-valine production using the modified bacterium.
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