Wee1 inhibitors and methods for treating cancer

Novel WEE1 inhibitors and degraders, represented by compounds of Formula (I), address the inadequacies of existing treatments by targeting cancer cells to induce mitotic catastrophe and enhance tumor sensitivity to DNA-damaging agents, offering a broad spectrum of cancer treatment options.

WO2026128433A1PCT designated stage Publication Date: 2026-06-18RECURIUM IP HLDG LLC

Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
RECURIUM IP HLDG LLC
Filing Date
2025-12-09
Publication Date
2026-06-18

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Abstract

Compounds of general Formula (I) are provided herein. Such compounds, as well as pharmaceutically acceptable salts and compositions thereof, are useful for treating diseases or conditions, including conditions characterized by excessive cellular proliferation, such as breast cancer.
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