Polysaccharide with antioxidant activity, cytotoxic activity against different types of cancer cells, and healing activity
A polysaccharide from Bovistella utriformis addresses the need for naturally derived treatments by demonstrating cytotoxicity against cancer cells and wound-healing properties, with low toxicity to healthy cells, while providing antioxidant benefits.
Patent Information
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- UNIV DE MAGALLANES
- Filing Date
- 2026-01-08
- Publication Date
- 2026-07-23
AI Technical Summary
Existing treatments for cancer, such as chemotherapy and radiotherapy, cause significant side effects, and there is a need for naturally derived formulations that exhibit cytotoxic activity against various types of cancer cells, antioxidant properties, and wound-healing properties.
A polysaccharide extracted from the fungus Bovistella utriformis, specifically from Chilean Patagonia, is obtained through a process involving depigmentation with ethanol, removal of phenolic compounds with polyvinylpolypyrrolidone, and precipitation with cold absolute ethanol, demonstrating cytotoxic activity against human colon cancer, lung cancer, melanoma, and leukemia cells, as well as antioxidant and wound-healing properties.
The polysaccharide shows high specificity against tumor cells with low toxicity to healthy cells, exhibiting significant cytotoxic and antioxidant activities, and effective wound-healing capabilities.
Smart Images
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