Bacteria TRIZ Cases

A fermented composition of fruits, vegetables, and cereals promotes beneficial intestinal bacteria growth.

Assigning agro/micro-pedoclimate values to soil samples enables targeted formation of endogenous azotobacterial consortia.

Targeted mutations in amino acid dehydrogenase expand substrate spectrum and increase reaction activity over 50 times, reducing industrial production costs.

Faecalibacterium butyricigenerans strain AF52-21 produces short-chain fatty acids to restore intestinal microflora balance.

Adapted microorganism consortium ferments protein monosubstrates to produce methane, overcoming ammonia inhibition that reduces yield.

Reducing homolanthionine accumulation by tuning MetB and MetC expression resolves production efficiency bottlenecks.

Amino acid substitutions at positions 183, 301, and 382 stabilize the enzyme against thermal denaturation, sustaining photosynthesis during heat stress.

Engineered recombinant microbial cells degrade organophosphates and generate electrochemical signals for sensitive product detection.

Recoded bacterial genomes prevent phage infection during manufacturing, sustaining continuous polypeptide production without efficiency loss.

A homologous system for producing D-xylonate in coryneform bacteria utilizes enhanced endogenous enzyme expression.

Nutrient-fed microbial plugs reduce channel permeability, forcing injection liquid into unswept oil zones and improving recovery degree.

Mannheimia succiniciproducens PALK mutant produces high succinic acid concentrations.

Co-expressing Bacillus-derived PonA, OppA, and SppA factors in recombinant protein production systems.

Reduced Tsp protease activity preserves protein integrity while DsbC mediates folding to sustain cell viability.

Granulated activated carbon supports biofilm to adsorb hydrophobic pollutants, resolving low bioavailability that slows in situ remediation.

Amino acid mutations in fungal terpene synthases improve activity and selectivity, resolving insufficient enzyme performance.

A composite material of straw biochar and Bacillus subtilis ASD05 reduces soil cadmium levels by 40 to 60 percent.

Novel Bacillus subtilis mutant strains enhance secretory productivity of cellulase and protease through targeted genomic deletions.

Oscillospiraceae sp. LBM10036 synthesizes caproic acid from diverse substrates including starch and lactic acid.

Photosynthetic microbes convert light into mechanical force to create micron-scale tunable sensors.

Harnessing endogenous Type I-F CRISPR-Cas machinery minimizes cytotoxicity while enabling precise, multi-site genome editing in Zymomonas mobilis.

Extrusion transforms dried bacterial biomass into digestible meat analogues, eliminating endotoxin risks while replicating texture.

Single-vessel culture design using defined media profiles controls microbial community composition while reducing production costs and labor.

Bacillus velezensis HL-5 degrades fats and proteins in shellfish homogenate to increase heparin extraction rates.

Mutated ImpE1 and ImpE2 proteins boost Corynebacterium IMP export, resolving low yield bottlenecks from inefficient microbial fermentation.

Serratia plymuthica I-4604 converts sucrose to turanose in one step, bypassing complex multi-enzyme processes and reducing industrial production costs.

Nonsolvent addition induces spherical L-threonine crystallization, resolving low yield and poor flowability caused by needle-shaped crystals.

Engineered E. coli converts O-phosphoserine into cysteine using sulfhydrylase, bypassing toxic intermediates and improving production efficiency.

Nutrient-regulated metabolic pathways in cyanobacteria transform CO2 into biofuels, eliminating sugar dependency and reducing water consumption.

Engineered microorganisms secrete fatty acids via thioesterase expression, bypassing slow plant oil extraction cycles.

Engineered methanotrophic bacteria express exogenous nucleic acids encoding multi-carbon substrate utilization pathways for growth on glucose and acetate.

Bacillus pumilus strain XH195 ferments glucose to 63 g/L acetoin, avoiding chemical catalysts and harsh conditions.

Suppressing cell wall binding proteins in cyanobacteria enables extracellular protein secretion, eliminating cell disruption and reducing production costs.

Co-culturing segmented filamentous bacteria with eukaryotic host cells overcomes fifty-year culturing barriers.

Dissolving un-film-form chitosan with cells creates a co-crosslinked membranous product, avoiding toxic reagents and high-temperature processes.

Deleting the arginine repressor gene in Corynebacterium removes feedback inhibition to boost L-arginine yield.

Inert atmosphere spray freezing preserves strict anaerobic bacteria viability without oxidative stress.

A probiotic composition comprising specific Lactobacillus and Pediococcus strains modulates the immune system to produce antibodies.

Bifidobacterium bifidum HEM972 increases beneficial short chain fatty acids while inhibiting isobutyrate to resolve intestinal flora imbalance.

Deleting relA and spoT genes reduces (p)ppGpp accumulation, enabling efficient butanol fermentation despite host toxicity.

Modified promoter and ribosome binding site sequences control expression levels to boost biosynthetic product yield without increasing system complexity.

Engineered host cells channel HMG-CoA through the mevalonate pathway to prevent toxicity while boosting isoprenoid yields.

Dynamic promoter control balances glycolic acid yield with strain stability across generations.

A microbial expression system uses extrachromosomal DNA with glycerine-3-phosphate dehydrogenase genes to produce polypeptides without antibiotic selection markers.

Myomegalin variant 8 maintains Golgi integrity during microtubule depolymerization cycles to prevent fragmentation.

Modified bacterial spores employ thymine starvation to eliminate environmental persistence risks while maintaining safe genetic modification capabilities.

Engineered anti-TIM-3 antibody resolves insufficient cytotoxicity by modifying Fc regions to enhance ADCC activity via optimized NK cell binding.

Lactobacillus paracasei K71 adheres to polished white rice surfaces through natural fermentation processes.