A chromatography column uses gamma-irradiated resin to capture recombinant proteins in closed manufacturing systems.
Recovering excess mRNA nucleotide caps via filtration and ion exchange reduces production costs by recycling valuable reagents with purities exceeding 90%.
Mixed mode cation exchange chromatography separates full from empty adeno-associated virus capsids, resolving low purity issues in gene therapy manufacturing.
Dispersion polymerization of crosslinkable monomers in aqueous media yields spheroid polymer particles with controlled diameter ratios.
Cation-exchange resins recover cobalt and tungstic acid from spent catalytic waters, reducing disposal costs.
Weakly basic anion exchangers remove free fatty acids to prevent thermal decomposition during distillation.
Thiol-functionalized silane networks bind perfluoroalkyl substances, reducing concentrations below 80 parts-per-trillion for cost-effective filtration.
A fluidic sample immobilization method uses a gel matrix to hold the sample in place during waiting periods.
Supersaturating allantoin co-precipitates endotoxins before void exclusion chromatography purifies protein samples.
Weak-base anionic ion exchange resins in a mixed bed remove ionic contaminants to 0.1 ppb without inducing hydrolysis reactions.
Mixed-mode ligands separate monomeric antibodies from aggregates through controlled buffer conditions.
A fermentation broth separation method uses base compounds to react ethyl acetate and adsorbents to capture thiols before distillation.
Replacing toxic hexamethyleneimine with cycloalkylamines reduces synthesis hazards while maintaining structural integrity through seeded crystallization.
Adding alkylglycoside detergent during anion exchange chromatography reduces endotoxin contamination below 30 EU/mg in plasmid DNA purification.
Selective leaching with sulfuric acid and chlorine extracts precious metal ions while preserving the crystal structure integrity of the molecular sieve support.
A terminal-block ionomer cathode catalyst layer with aggregated hydrophilic blocks retains water effectively.
Compacting alpha-hydrous tin dioxide allows low pressure 82Rb delivery, resolving flow control constraints in 3D PET cardiac imaging systems.
A chromatographic sequential simulated moving bed system uses active and inactive flow paths to fractionate feedstock into enriched product streams.
A secondary circuit removes calcium from plasma water to enable regional anticoagulation in extracorporeal circulation.