Component Separation TRIZ Cases
- Mass Spectrometric Assay for Low-Abundance Proteins Without Standards
Parent-daughter ion transition monitoring identifies proteolytic fragments to quantify low-abundance proteins without standard samples.
- Immunochromatographic Assay Signal Amplification via Indicator Size Control
A method for immunochromatographic assays uses differential indicator particle sizes to control flow rates and amplify detection signals.
- Retention Time Prediction Model for LC-MS Peptide Analysis
Computational model predicts analyte retention times using amino acid sequences and physicochemical properties.
- Ion Source Liquid Sample Introduction System with Dual-Function Gas
Atomization-promoting gas supplies and nebulizes liquid samples through a switching unit, eliminating separate gas sources and reducing unnecessary consumption.
- Residual Host Cell Protein Detection via LC-MS/MS
Protease digestion and sodium deoxycholate treatment prepare protein samples for highly sensitive LC-MS/MS analysis.
- Natural Substance Complexation for Food Flavor Stability
IMAC isolates natural substances that complex with Ni2+, Cu2+, and Fe2+ ions, preventing oxidative degradation without removing essential minerals.
- Ammonia Generation Device for GC/CI-MS/MS Safety
On-demand ammonia generation via thermal decomposition and amine absorption eliminates compressed gas safety hazards in mass spectrometry.
- Chromatograph Mass Spectrometer Data Acquisition Consistency
Segmenting the analysis period allows dynamic MSn scheduling, maintaining constant data acquisition intervals despite varying analysis counts.
- Low Melting Agarose Matrix for Stable Expansion Microscopy
Low melting agarose reinforces hydrogel matrices, resolving sample instability during expansion microscopy of large organs.
- Platinum-Labeled Probes for Mass Cytometry Channel Expansion
Platinum-conjugated reagents expand detection channels in mass cytometry while avoiding xenon and barium contamination.
- Multiplexed Analyte Characterization Using Dye-Tagged Affinity Molecules
Integrating multiple detectors into a single liquid chromatography platform reduces assay time and reagent consumption while maintaining measurement precision.
- Chromatograph Mass Spectrometer Precursor Ion Exclusion
Dynamic m/z range exclusion prevents repetitive precursor ion selection in chromatograph mass spectrometers, ensuring broader component coverage.
- Integrated Nanospray Package for LC-MS Assembly
An integrated nanospray package merges the emitter, column, and high-voltage contact into a single disposable unit.
- Sealed Sampling Cartridge for Pollutant Extraction
A sealed sampling cartridge uses pierceable silicone and aluminum caps to maintain sample integrity during passive or active fluid extraction.
- SARS-CoV-2 Spike Protein Binding Molecule for Specific Infection Blockade
Tailored CDR sequences in the binding molecule block ACE2 receptor interaction, resolving limited therapeutic effects of broad-spectrum antivirals.
- Variable Thickness Membrane for Gas Analyzer Vapor Pressure Contradiction
A variable thickness membrane separates analyte molecules from carrier gas in a mass spectrometer interface.
- Batch Chemical Analyzer Valve Segmentation for Clogging Prevention
Segmenting the closed loop isolates the multi-port valve from circulation, preventing foreign substance accumulation and clogging.
- Mobile Phase Tare Weight Determination for Liquid Chromatography
A control device determines mobile phase container tare weight using initial gross weight and volume data.
- Galacto-oligosaccharide Quantification via C30 Chromatography
Derivatizing reagents and C30 reverse-phase chromatography resolve overlapping peaks between 4'-GL and maltotriose, ensuring precise measurement.
- Supercritical Fluid Chromatography for Rapid Infection Diagnosis
Supercritical fluid chromatography separates quorum sensing molecules to identify pathogens, bypassing 48-hour culture delays for rapid clinical diagnosis.
- Piston Movement Compensation for Thermal Expansion in Metering Devices
Superposing corrective piston movements to counteract thermal expansion and contraction effects during fluid compression.