Heating Or Cooling Apparatus TRIZ Cases

Elastic PDMS upper plate seals micro-channels under pressure, preventing fluid evaporation during PCR analysis.

Modular automated system isolates and amplifies nucleic acids via magnetic separation and thermal cycling for rapid pathogen detection.

A PCR system uses reversible electrowetting to reshape liquid samples between thin films and droplets.

Passively tunable porosity in a selective venting element prevents liquid leakage while maintaining gas flow for accurate biological assay detection.

A paper chip structure with reaction and channel pads enables isothermal nucleic acid amplification.

A portable nucleic acid sequencing kit houses DNA extraction, preparation, and sequencer systems within a single enclosure.

Integrated microfluidic platform couples bacterial identification with antibiotic susceptibility testing using digital PCR.

Segmented flow in a serpentine channel reduces pressure loss and accelerates annealing, resolving air bubble formation that stalls continuous PCR reactions.

Disposable microfluidic chips use glass substrates to resolve cross-contamination risks from reusable designs while maintaining thermal stability.

Insulation partitions restrict heat transfer between place holders, reducing cross-contamination risks during automated nucleic acid extraction.

Stacked fluidics layers integrate a CMOS biosensor to preserve the active detection area while membrane valves seal PCR regions against microbubble expansion.

A thermal cycler uses annular conveying and pressing blocks to ensure uniform contact between slide plates and heating elements.

Segmented droplets flow through temperature-controlled zones, scaling PCR volume without increasing device complexity.

Variable local resistance in the conductive layer compensates for edge heat loss, resolving temperature non-uniformity in dPCR chips.

A solid fluorescence standard uses quantum dots in a curable adhesive matrix for instrument calibration.

Multi-level storage uses flat springs to hold containers, reducing reloading frequency while maintaining stability during pipette lid penetration.

Segmented breaking features allow multi-well plates to divide manually into strips, preventing sharp edges and reagent wastage.

Segmenting samples into microfluidic emulsion droplets isolates rare targets, resolving detection limits caused by high copy number dominance.

Hydrophobic chamber walls separate bubbles from the optical path to maintain signal sensitivity during simultaneous nucleic acid amplification.

Segmenting the loading spaces with a transparent window maintains 37°C for reactions and 25°C for laser diodes, resolving conflicting thermal requirements.

Integrated microfluidic cartridges paired with automated control units resolve reproducibility issues in decentralized molecular diagnostics.

Integrated fluidic channels and plungers enable parallel sample processing, reducing reagent consumption and contamination risks.

A cartridge interface module integrates fluidics, PCR assembly, high voltage electrodes, and detection optics within a microfluidic cartridge.

An integrated electrophoresis cartridge engages a system to automate sample preparation and analysis.

Spatially separated pores in a porous matrix prevent target interference, enabling accurate multiplex detection.

A syringe plunger incorporates a porous sintered polymer filter layer that swells upon contact with liquid to block air movement.

Optical reflection from a rotating test bar measures rotational angle changes, resolving measurement precision versus position stability contradictions.

Electric fields disrupt immiscible label interfaces in microfluidic channels to prevent cross-contamination between sequentially introduced reagents.

Mechanical filtration separates circulating tumor cells by size, enabling viable retrieval and multiplexed analysis without antibody-induced damage.

Electromagnetic heating layers transform energy into heat within compressed sample layers, reducing evaporation during rapid PCR cycles.

Segmenting the cover into a base plate, hinged lid, and removable insert resolves the contradiction between structural stability and ease of cleaning.

Movable thermal zones and wiper elements divide samples for rapid cycling, reducing contamination risks in multiplex diagnostic assays.

A portable molecular diagnostic device performs sample preparation and nucleic acid amplification via single-step actuation.

Silicon microfluidic substrate bonded to a CMOS lid propagates fluid samples via capillary action without external pumps.

An extendable sampling tube enveloped by a continuous immiscible fluid flow prevents gas introduction, eliminating system downtime and re-equilibration needs.

Segmented microfluidic chips concentrate aflatoxin twenty-fold in under twenty minutes, enabling source tracing without complex laboratory chromatography.

A disposable reaction cartridge integrates sample collection, filtration, and nucleic acid amplification into a single unit.

Segmentation isolates rare targets from excess backgrounds, improving assay fidelity and reducing reagent costs.

Splitting samples into nanoliter volumes eliminates calibration curve variability to ensure accurate quantification.

A movable support element accommodates microarray thermal expansion during PCR cycling, preventing mechanical stress and cartridge breakage.

Continuous droplet flow microfluidic system generates nanoliter sample plugs for multiplexed genetic detection assays.

Processor manipulates reagents in a closed cassette to deposit amplified DNA on a microarray, reducing contamination risks during rapid diagnostic testing.

An integrated microfluidic device automates viral RNA extraction and amplification using a dedicated flow control module.

Laser scattering identifies transparent microorganisms via attractant binding, reducing sample volume requirements.