In-Vivo Testing Preparations TRIZ Cases
- Porous Matrix Hyperpolarization for Stronger NMR Signal Transfer
A nanoporous matrix co-confines parahydrogen and target molecules to boost spin polarization without cryogenic DNP or microwave hardware.
- Combination Cancer Therapy Using Autophagy Inhibition Against Drug Resistance
Combining anti-parasitic agents with autophagy inhibitors helps overcome rapid drug resistance and improve chemotherapy response in pancreatic and liver cancers.
- A38C Near-IR Imaging Composition for Microscopic Carcinoma Detection
A low-endotoxin A38C-ALEXA647 probe boosts tumor signal-to-noise ratio, enabling detection of microscopic carcinoma nodules during surgery.
- Zwitterionic Disease-Targeted NIR Imaging Agents for Low Background
Zwitterionic fluorophores pair antigen-specific vectors with charge balance to reduce background uptake and improve NIR target-to-background ratio.
- Biogenic Hemin MRI Contrast Agents for Safer T1 Imaging
Replacing gadolinium or manganese, iron-containing hemin agents enhance T1 relaxation while supporting biodegradability and improved biosafety.
- Radicaloid TTFtt Bimetallic Complexes for Bright NIR-II Imaging
Low-PLQY NIR-II dyes limit biological imaging; redox-switchable TTFtt bimetallic complexes offer bright, air- and water-stable emission.