Phosphorus-Oxygen Lyases TRIZ Cases
- GUCY2C-CD3 Antigen-Binding Molecule for Targeted T-Cell Tumor Killing
A dual-target GUCY2C-CD3 binder improves T-cell synapse formation and tumor cell killing in gastrointestinal cancers.
- C-Terminal OaPAC Truncation for Low-Light Photoactivation
Deleting 1-18 C-terminal residues from OaPAC boosts photoactivation efficiency, enabling lower light use and reducing photodamage risk.
- Immune Cell Targeting Probe for Pre-Targeted Drug Delivery
A pre-targeting probe binds immune cells before payload delivery, helping reduce off-target toxicity and support flexible drug loading.
- Pyripyropene Biosynthetic Gene Cluster Isolation and Expression
Isolating the pyripyropene biosynthetic gene cluster resolves low productivity bottlenecks by enabling targeted genetic transformation of host strains.
- VHH Binding Antibodies Neutralizing Anthrax and Botulinum Toxins
Recombinant VHH binding proteins neutralize anthrax and botulinum toxins through specific molecular recognition.
- Butelase 1 Enzyme for Peptide Cyclization
Butelase 1 enzyme recognizes Asx-His-Val motifs to cleave sorting sequences and ligate residues, eliminating slow overnight incubation times.
- Adenylate Cyclase Regulation for Fine Chemical Production
Deletions in adenylate cyclase regulatory domains boost cAMP levels to drive fine chemical synthesis.
- Mutated Squalene-Hopene Cyclase for Terpene Cyclization
Targeted mutations in squalene-hopene cyclase resolve the contradiction between cyclization efficiency and stereospecificity during terpene processing.
- Adenylate Cyclase-Calmodulin Protein Interaction Detection
Reduced AC-CaM affinity enables high-sensitivity detection of toxic proteins by minimizing background noise while maintaining selectable traits.