Method and system for improving stimulation of excitable tissue

The method optimizes DBS electrode stimulation patterns by selecting a subset based on patient feedback and reducing energy consumption, addressing specificity and biocompatibility issues, thus improving therapeutic efficacy and battery life.

CA2987936CActive Publication Date: 2026-09-22NEURONANO AB
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Patent Information

Application Number
CA2987936
Authority / Receiving Office
CA · CA
Patent Type
Patents
Current Assignee / Owner
Priority Date
2015-07-10
Filing Date
2016-06-03
Publication Date
2026-09-22
Estimated Expiration
2036-06-03

AI Technical Summary

Technical Problem

Existing deep brain stimulation (DBS) probes face limitations in stimulation specificity, biocompatibility, and energy efficiency due to large electrode surfaces, unpredictable optimal stimulation sites, and glial scarring, leading to side effects and reduced therapeutic efficacy.

Method used

A method and system for optimizing the stimulation pattern of implanted electrodes by selecting a subset of electrodes based on patient feedback, assigning values to each electrode, and reducing energy consumption through parameter optimization, using microelectrodes and focused current distribution.

Benefits of technology

This approach enables time-efficient identification of electrodes providing therapeutic effects while minimizing side effects and energy consumption, enhancing stimulation specificity and battery life.

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Abstract

A method for optimization of the stimula- tion pattern of a set of implanted electrodes in excitable tis- sue of a patient is disclosed, wherein it comprises the steps of: (a) choosing a first group of a certain number of from said set of implanted electrodes, (b) stimulating the excit- able tissue electrically by said first group of electrodes, (c) registering information provided by the patient, (d) assign- ing each electrode of said first group of electrodes a value related to said information, wherein these steps are repeated for one or more further groups of said certain number of electrodes chosen from said set of implanted electrodes, wherein each electrode may be included in one or several groups, wherein the total assigned value for each electrode is calculated, and wherein electrodes having a total as- signed value exceeding a predetermined value or a prede- termined number of the electrodes having the highest total assigned value are chosen to be included in said stimulation pattern, as well as a method for treatment or alleviation of a disease or condition by use of a set of electrodes whose stimulation pattern has been optimized with said method, and a system for optimization of the stimulation pattern.
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