An electric pipetting device and method based on a pressure sensor

By using an electric pipetting device based on a pressure sensor, the problems of cumbersome operation and poor sealing at the connection of manual pipettes have been solved, realizing automated and precise control and cleaning functions, and improving pipetting efficiency and connection stability.

CN118022876BActive Publication Date: 2025-10-28UNIV OF SCI & TECH OF CHINA
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Patent Information

Application Number
CN202410383736.5
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-04-01
Publication Date
2025-10-28
Estimated Expiration
2044-04-01

AI Technical Summary

Technical Problem

Existing manual pipettes require frequent manual pressing during large-volume pipetting operations, making it difficult to simulate the dispensing method of manual operation. The connection points have poor sealing performance and are prone to liquid contamination.

Method used

An electric pipetting device based on a pressure sensor is used, including a fixing component, a clamping component, and a cleaning component. The pressure sensor detects the resistance of the suction and discharge rods to control the movement of the pusher, thereby achieving automated operation. The clamping component fixes the connection, and the cleaning component removes residual liquid.

Benefits of technology

It enables precise control of pipetting volume, reduces liquid loss, improves connection stability, and cleans manual pipette tips to prevent liquid contamination.

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Abstract

This invention relates to an electric pipetting device and method based on a pressure sensor. The device includes a manual pipette with a suction / dissipation rod pressing part, a tap tube pressing part, and a pipette tip, and a disposable pipette tube that engages with the manual pipette tip. It also includes a fixing assembly for supporting and fixing the manual pipette. The fixing assembly has two pushing parts: a first pushing part and a second pushing part. The telescopic end of the first pushing part is sequentially equipped with a pressure sensor mounting bracket and a pressure sensor. This invention uses the pressure sensor to detect that the resistance encountered by the suction / dissipation rod pressing part is within a target value range. The first pushing part pauses and then continues to extend, simulating manual operation. It first presses to the first position, pauses for a period of time to allow the remaining liquid to accumulate, and then presses to the second position to expel all the remaining liquid. This method better expels all the liquid, thereby achieving precise control of the pipetting volume and reducing liquid loss during the pipetting process.
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