Pig lactation-related snp molecular marker and application thereof

By screening for the SNP site rs331986593 in the HS6ST2 gene, developing a reagent kit and detection method, the problem of measuring sow lactation capacity was solved, enabling early selection and efficient breeding of sows, and improving sow lactation performance.

CN118957096BActive Publication Date: 2026-04-21HUAZHONG AGRI UNIV
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Patent Information

Application Number
CN202411240393.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-09-04
Publication Date
2026-04-21
Estimated Expiration
2044-09-04

AI Technical Summary

Technical Problem

Existing technologies cannot effectively measure sow lactation performance, and the direct link between genes affecting milk composition and sow lactation capacity traits has not been determined, resulting in low breeding efficiency.

Method used

The SNP site rs331986593 was screened in the HS6ST2 gene, and corresponding kits and detection methods were developed. The lactation capacity of sows was predicted by detecting their genotypes, and the SNP marker was used for early selection to optimize breeding.

Benefits of technology

It enables accurate and efficient prediction of sow lactation capacity, shortens generation intervals, increases selection intensity and breeding efficiency, and improves sow lactation performance.

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Abstract

This invention discloses a porcine lactation-related SNP molecular marker and its application. The SNP site of the molecular marker is located on the X chromosome, with RS number rs331986593. Compared to sows carrying the CC genotype, sows carrying the CT or TT genotypes have higher lactation capacity. This molecular marker can accurately predict differences in lactation trait among sows of different genotypes, enabling accurate and efficient selection of superior pig breeds with excellent lactation performance. It has outstanding advantages such as simplicity, speed, high sensitivity, and good specificity. In pig breeding, this molecular marker can serve as a reliable marker for lactation trait, facilitating early selection, thereby shortening the generation interval, increasing selection intensity, and improving selection efficiency and accuracy.
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