A rs338618851 site snp molecular marker related to pork production efficiency of pigs and application thereof

By discovering the rs338618851 SNP molecular marker in the promoter region of the pig FHL3 gene, the problem of low breeding efficiency of pig meat production traits in existing technologies has been solved, realizing efficient and precise molecular marker-assisted selection, and improving the growth performance and meat quality characteristics of pigs.

CN119120723BActive Publication Date: 2026-07-07HUAZHONG AGRI UNIV
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Patent Information

Application Number
CN202411329471.7
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-09-23
Publication Date
2026-07-07
Estimated Expiration
2044-09-23

AI Technical Summary

Technical Problem

Existing technologies lack effective molecular marker-assisted selection methods when selecting complex traits in pigs, such as meat production traits, resulting in low breeding efficiency and difficulty in accurately improving pig growth performance and meat quality characteristics.

Method used

The SNP molecular marker rs338618851, located in the promoter region of the porcine FHL3 gene, was discovered and validated. The association between this SNP site and the meat production trait in pigs was detected by direct sequencing. This marker was used for marker-assisted selection to screen for breeding pigs with excellent growth performance and meat quality characteristics.

Benefits of technology

It has significantly improved the efficiency of pig breeding, shortened the breeding cycle, optimized the genetic structure of pigs, and enhanced the competitiveness of the pork industry.

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Abstract

The application discloses a SNP molecular marker of a site rs338618851 related to pork production efficiency of pigs and application. The genetic marker is cloned from a 93991071 site of a chromosome 6 of pigs. American Landrace pigs are selected as test materials, whole genome DNA is extracted from blood of the pigs, and a primer is designed according to a pig genome sequence NC_010448.4 published in an NCBI database. A base substitution of T or C exists at a 172th position of a primer amplification sequence, the substitution causes polymorphism at the position. The SNP site is typed through a direct sequencing technology, and correlation analysis shows that, compared with other gene individuals, a TT genotype individual at the 172th position is large in birth weight, large in eye muscle area and short in time to reach 100 kg at a certain age. The application provides a new marker for molecular breeding of pork production traits of pigs.
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