Bacillus pumilus P2-7 and application thereof in disease prevention and control in prawn culture

By utilizing the phage activity of heat-resistant Bacillus simulans P2-7, the application of Gram-positive phage probiotics in shrimp farming has been insufficient. This approach effectively inhibits various pathogenic bacteria and controls multiple diseases, thereby improving the survival rate of shrimp.

CN119662452BActive Publication Date: 2026-05-01SHANDONG ACAD OF MARINE SCI (QINGDAO NAT MARINE SCI RES CENT) +1
5 Cites 0 Cited by

Patent Information

Application Number
CN202411650751.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-11-19
Publication Date
2026-05-01
Estimated Expiration
2044-11-19

AI Technical Summary

Technical Problem

In the existing technology, Gram-negative phage probiotics are widely used in the prevention and control of diseases in shrimp farming, but research and application of Gram-positive phage probiotics are relatively limited, and existing methods are difficult to effectively control a variety of pathogenic bacteria in water and common diseases in shrimp farming.

Method used

Thermoresistant Bacillus simulans P2-7 is used to eliminate pathogenic bacteria in the water through phage, including Pseudomonas aeruginosa and Shewanella algae, to control Shewanella disease and other common diseases in shrimp, such as septicemia, acute hepatopancreatic necrosis, and white spot syndrome.

Benefits of technology

It significantly inhibits multiple pathogenic bacteria in the water, increases the protection rate of shrimp against Shevavirus disease by 82%, and prevents multiple shrimp farming diseases, with a survival rate of 96%.

✦ Generated by Eureka AI based on patent content.
Patent Text Reader

Abstract

This invention provides a thermoresistant Bacillus pumilus P2-7 strain and its application in the prevention and control of diseases in shrimp farming, belonging to the field of bioengineering technology. The thermoresistant Bacillus pumilus P2-7 strain provided by this invention was deposited at the Guangdong Provincial Microbial Culture Collection Center on November 4, 2024, with accession number GDMCC NO.65408. This strain differs from traditional antibacterial Bacillus strains in its antagonistic mechanism; it does not secrete metabolites with antibacterial activity, but rather exerts its effects through phage therapy. It can significantly eliminate / inhibit pathogenic bacteria in water and effectively control Shevax disease in shrimp. It also shows good efficacy in simultaneously preventing septicemia, acute hepatopancreatic necrosis, white spot syndrome, and infectious hypodermal and hematopoietic tissue necrosis in shrimp farming.
Need to check novelty before this filing date? Find Prior Art