Streptomyces gilvosporeus ZY8 as well as fermentation seeds and application thereof
The S. thyroid thyroid ZY8 obtained through complex physicochemical mutagenesis screening can efficiently respond to the signal of Streptococcus neonatalis, significantly improve the synthetic yield of natamycin, solve the problem of low yield of existing strains, and achieve more efficient production of natamycin.
CN119776231APending Publication Date: 2025-04-08HUAIBEI NORMAL UNIVERSITY
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Patent Information
- Application Number
- CN202510105651.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-01-23
- Publication Date
- 2025-04-08
AI Technical Summary
Technical Problem
The current synthesis yield of natamycin of Streptococcus ATCC 13326 is relatively low, making it difficult to meet the needs of large-scale industrial production.
Method used
Through the screening of complex physicochemical mutagenesis, Streptococcus thoracicum ZY8 was obtained. This strain can efficiently respond to Streptococcus signal, strengthen natamycin synthesis, and improve its yield.
Benefits of technology
The yield of natamycin of Streptococcus thoracicum ZY8 is 1.57 times that of ATCC 13326, and under the influence of Streptococcus signal, the yield can reach 2.35 times, and even in a mixed fermentation system, the yield can reach 3.52 times.
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Abstract
The invention relates to the technical field of industrial biology, in particular to streptomyces gilvosporeus ZY8 and a fermentation seed and application thereof, the streptomyces gilvosporeus ZY8 is preserved in the China General Microbiological Culture Collection Center (CGMCC) on November 13, 2024, the preservation number is CGMCC No.32603, and the classification name is streptomyces gilvosporeus. The streptomyces gilvosporeus ZY8 is named as streptomyces gilvosporeus. The streptomyces gilvosporeus ZY8 provided by the invention has a better promoting effect in the aspects of mediating a streptomyces albidosus signal and enhancing the synthesis of natamycin.
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